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A/Prof

Bryony Nayagam

Associate Professor In Auditory Physiology
Audiology and Speech Pathology
Auditory neuroscience
Cell transplantation
Regeneration
Cochlear Implants
Hearing and Hearing Loss
Stem Cells
Neuroimaging
Audiology
Bioinformatics
Bryony Nayagam's Profile Picture
A/Prof

Bryony Nayagam

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Stem Cells and Regenerative Medicine
Bryony Nayagam's Profile Picture
A/Prof

Bryony Nayagam

 
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Projects

Displaying the 10 most recent projects from 11 for Bryony Nayagam.

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Understanding platinum dissolution in biomedical stimulating electrodes

2020 - 2025
Active
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University of Melbourne - University of Toronto Joint Research Program

Completed
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Regenerative therapies for the treatment of hearing loss

2015 - 2019
Completed
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Can stem cells make functional connections?

A major challenge in treating neurodegenerative conditions with stem cells, is to generate a population of donor cells which are capable of ..

2012 - 2017
Completed
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RESTORING HEARING IN THE DEAF COCHLEA USING STEM CELLS AND ELECTRICAL STIMULATION

2010 - 2014
Completed
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Cell transplantation into the deaf mammalian cochlea

2011 - 2014
Completed
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ASCC Postgraduate Supplementary Scholarship

2011 - 2014
Completed
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Restoring hearing using stem cells

One in four Australians is predicted to experience some form of hearing loss by 2050. Hearing loss is irreversible and the chief clinical tr..

2009 - 2014
Completed
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Combined treatment for hearing loss using stem cells and electrical stimulation

2011 - 2012
Completed
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Can human stem cells make functional contacts in vitro

2010 - 2011
Completed

11

Projects

Project Types

9

Research Grant

2

Internal Research Grant

Additional Information

Scholarly Works

Displaying the 10 most recent scholarly works from 69 for Bryony Nayagam.

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ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death (vol 100, pg 797, 2022)

Jacqueline M Ogier, Yujing Gao, Eileen M Dunne, Michael A Wilson, Sarath C Ranganathan, Gregory H Tesch, David J Nikolic Paterson, Alain Dabdoub, Rachel A Burt, Bryony A Nayagam, Paul J Lockhart

Journal article  |  2022  |  JOURNAL OF MOLECULAR MEDICINE-JMM

The numbers 432 and 433 found in the 6th paragraph of the Discussion section is not included in this paper and should be removed. ..

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ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death

Jacqueline M Ogier, Yujing Gao, Eileen M Dunne, Michael A Wilson, Sarath C Ranganathan, Gregory H Tesch, David JNikolic Paterson, Alain Dabdoub, Rachel A Burt, Bryony A Nayagam, Paul J Lockhart

Journal article  |  2022  |  JOURNAL OF MOLECULAR MEDICINE-JMM

Aminoglycoside antibiotics are lifesaving medicines, crucial for the treatment of chronic or drug resistant infections. However, a..

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Expression and Physiology of Voltage-Gated Sodium Channels in Developing Human Inner Ear

Rikki K Quinn, Hannah R Drury, Ethan T Cresswell, Melissa A Tadros, Bryony A Nayagam, Robert J Callister, Alan M Brichta, Rebecca Lim

Journal article  |  2021  |  FRONTIERS IN NEUROSCIENCE

Sodium channel expression in inner ear afferents is essential for the transmission of vestibular and auditory information to the c..

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Response of primary auditory neurons to stimulation with infrared light in vitro

William GA Brown, Karina Needham, James M Begeng, Alexander C Thompson, Bryony A Nayagam, Tatiana Kameneva, Paul R Stoddart

Journal article  |  2021  |  JOURNAL OF NEURAL ENGINEERING

Objective.Infrared light can be used to modulate the activity of neuronal cells through thermally-evoked capacitive currents and t..

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Response of primary auditory neurons to stimulation with infrared light in vitro.

William GA Brown, Karina Needham, James M Begeng, Alexander C Thompson, Bryony A Nayagam, Tatiana Kameneva, Paul R Stoddart

Journal article  |  2021  |  J Neural Eng

OBJECTIVE: Infrared light can be used to modulate the activity of neuronal cells through thermally-evoked capacitive currents and ..

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Fiber-Specific Changes in White Matter Microstructure in Individuals With X-Linked Auditory Neuropathy

Julien Zanin, Thijs Dhollander, Gary Rance, Lan Yu, Lan Lan, Hongyang Wang, Xin Lou, Alan Connelly, Bryony Nayagam, Qiuju Wang

Journal article  |  2020  |  EAR AND HEARING

OBJECTIVES: Auditory neuropathy (AN) is the term used to describe a group of hearing disorders, in which the hearing impairment oc..

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Electrochemical and biological characterization of thin-film platinum-iridium alloy electrode coatings: a chronic in vivo study

Ashley N Dalrymple, Mario Huynh, Bryony A Nayagam, Curtis D Lee, Greg R Weiland, Artin Petrossians, J John, III Whalen, James B Fallon, Robert K Shepherd

Journal article  |  2020  |  JOURNAL OF NEURAL ENGINEERING

OBJECTIVE: To evaluate the electrochemical properties, biological response, and surface characterization of an electrodeposited Pl..

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Electrochemical and biological performance of chronically stimulated conductive hydrogel electrodes

Ashley N Dalrymple, Ulises A Robles, Mario Huynh, Bryony A Nayagam, Rylie A Green, Laura A Poole-Warren, James B Fallon, Robert K Shepherd

Journal article  |  2020  |  JOURNAL OF NEURAL ENGINEERING

OBJECTIVE: Evaluate electrochemical properties, biological response, and surface characterization of a conductive hydrogel (CH) co..

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Thermal damage threshold of neurons during infrared stimulation

WGA Brown, K Needham, JM Begeng, AC Thompson, BA Nayagam, T Kameneva, PR Stoddart

Journal article  |  2020  |  Biomedical Optics Express

In infrared neural stimulation (INS), laser-evoked thermal transients are used to generate small depolarising currents in neurons...

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ASK1 inhibition: a therapeutic strategy with multi-system benefits

Jacqueline M Ogier, Bryony A Nayagam, Paul J Lockhart

Journal article  |  2020  |  JOURNAL OF MOLECULAR MEDICINE-JMM

p38 mitogen-activated protein kinases (P38α and β) and c-Jun N-terminal kinases (JNK1, 2, and 3) are key mediators of the cellular..

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Scholarly Works

Keyword Analysis

Neurosciences
Clinical Sciences
Clinical Health
Expanding Knowledge
Medical Biotechnology
Biomedical Engineering
Cognitive and Computational Psychology
Genetics
Biochemistry and Cell Biology
Medicinal and Biomolecular Chemistry

Honours, Awards and Fellowships

2008

Dean's Award for Excellence in a PhD Thesis

University of Melbourne
2007

Victoria Fellowship

Victorian Government
2006

Wagstaff Fellow in Otolaryngology

Royal Victorian Eye and Ear Hospital
2004

Melbourne Postgraduate Research Scholarship (MRS)

University of Melbourne
2000

Dean's Honour Roll

University of Tasmania
2020

University of Melbourne MDHS Faculty Fellowship

2014

Garnett Passe and Rodney Williams Memorial Foundation Research Fellowship (2015-2019)

2009

NH&MRC Australian-Based Biomedical Research Fellowship

2007

Victoria Fellowship

2006

Junior Wagstaff Fellowship in Otolaryngology

10

Awards

Credentials

Positions

Associate Professor In Auditory Physiology

Audiology and Speech Pathology

Honorary

Ophthalmology Eye and Ear Hospital

Member

Australasian Society for Stem Cell Research

Executive Committee Member

Australian-French Association for Science and Technology

Education

Melbourne Teaching Certificate

University of Melbourne

Biomedical Research Management

University of Melbourne

PhD (Auditory Neuroscience & Stem Cell Molecular Biology)

University of Melbourne

Doctor of Philosophy

University of Melbourne

Links

International Linkages

Harvard Medical School

United States

Johns Hopkins University

United States