Bryony Nayagam

Response of primary auditory neurons to stimulation with infrared light in vitro

William GA Brown, Karina Needham, James M Begeng, Alexander C Thompson, Bryony A Nayagam, Tatiana Kameneva, Paul R Stoddart

Journal article  |  2021  |  JOURNAL OF NEURAL ENGINEERING

Objective.Infrared light can be used to modulate the activity of neuronal cells through thermally-evoked capacitive currents and t..

Fiber-Specific Changes in White Matter Microstructure in Individuals With X-Linked Auditory Neuropathy

Julien Zanin, Thijs Dhollander, Gary Rance, Lan Yu, Lan Lan, Hongyang Wang, Xin Lou, Alan Connelly, Bryony Nayagam, Qiuju Wang

Journal article  |  2020  |  EAR AND HEARING

OBJECTIVES: Auditory neuropathy (AN) is the term used to describe a group of hearing disorders, in which the hearing impairment oc..

Electrochemical and biological characterization of thin-film platinum-iridium alloy electrode coatings: a chronic in vivo study

Ashley N Dalrymple, Mario Huynh, Bryony A Nayagam, Curtis D Lee, Greg R Weiland, Artin Petrossians, J John, III Whalen, James B Fallon, Robert K Shepherd

Journal article  |  2020  |  JOURNAL OF NEURAL ENGINEERING

OBJECTIVE: To evaluate the electrochemical properties, biological response, and surface characterization of an electrodeposited Pl..

Thermal damage threshold of neurons during infrared stimulation

WGA Brown, K Needham, JM Begeng, AC Thompson, BA Nayagam, T Kameneva, PR Stoddart

Journal article  |  2020  |  Biomedical Optics Express

In infrared neural stimulation (INS), laser-evoked thermal transients are used to generate small depolarising currents in neurons...

Electrochemical and biological performance of chronically stimulated conductive hydrogel electrodes

Ashley N Dalrymple, Ulises A Robles, Mario Huynh, Bryony A Nayagam, Rylie A Green, Laura A Poole-Warren, James B Fallon, Robert K Shepherd

Journal article  |  2020  |  JOURNAL OF NEURAL ENGINEERING

OBJECTIVE: Evaluate electrochemical properties, biological response, and surface characterization of a conductive hydrogel (CH) co..

ASK1 inhibition: a therapeutic strategy with multi-system benefits

Jacqueline M Ogier, Bryony A Nayagam, Paul J Lockhart

Journal article  |  2020  |  JOURNAL OF MOLECULAR MEDICINE-JMM

p38 mitogen-activated protein kinases (P38α and β) and c-Jun N-terminal kinases (JNK1, 2, and 3) are key mediators of the cellular..

Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices

Tomoko Hyakumura, Stuart McDougall, Sue Finch, Karina Needham, Mirella Dottori, Bryony A Nayagam

Journal article  |  2019  |  Stem Cells International

Stem cells have been touted as a source of potential replacement neurons for inner ear degeneration for almost two decades now; ye..

A Comparison of Electrical Stimulation Levels Across Ears for Children With Sequential Bilateral Cochlear Implants

Karyn L Galvin, Roghayeh Abdi, Richard C Dowell, Bryony Nayagam

Journal article  |  2019  |  EAR AND HEARING

OBJECTIVES: To compare threshold and comfortable levels between a first and second cochlear implant (CI) for children, and to cons..

Review: Using diffusion-weighted magnetic resonance imaging techniques to explore the microstructure and connectivity of subcortical white matter tracts in the human auditory system

Julien Zanin, Thijs Dhollander, Shawna Farquharson, Gary Rance, Alan Connelly, Bryony A Nayagam

Journal article  |  2019  |  HEARING RESEARCH

Since its inception 30 years ago, diffusion-weighted magnetic resonance imaging (dMRI) has advanced to become a common component o..

Organotypic Culture of Neonatal Murine Inner Ear Explants

Jacqueline M Ogier, Rachel A Burt, Hannah R Drury, Rebecca Lim, Bryony A Nayagam

Journal article  |  2019  |  FRONTIERS IN CELLULAR NEUROSCIENCE

The inner ear is a complex organ containing highly specialised cell types and structures that are critical for sensing sound and m..