Garrett Ng

Effect of MUC1 length polymorphisms on the NLRP3 inflammasome response of human macrophages

Poshmaal Dhar, Sohinee Sarkar, Garrett Z Ng, Paul Kalitsis, Muhammad A Saeed, Michael A McGuckin, Justine A Ellis, Philip Sutton

Journal article  |  2019  |  Human Immunology

Mucin 1 is a cell-membrane associated mucin, expressed on epithelial and immune cells that helps protect against pathogenic infect..

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

Bethany M Anderson, Daniel P Poole, Luigi Aurelio, Garrett Z Ng, Markus Fleischmann, Paulina Kasperkiewicz, Celine Morissette, Marcin Drag, Ian R van Driel, Brian L Schmidt, Stephen J Vanner, Nigel W Bunnett, Laura E Edgington-Mitchell

Journal article  |  2019  |  Scientific Reports

Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations

Jon N Buzzelli, Louise O'Connor, Michelle Scurr, Sharleen Chung Nien Chin, Angelique Catubig, Garrett Z Ng, Masanobu Oshima, Hiroko Oshima, Andrew S Giraud, Philip Sutton, Louise M Judd, Trevelyan R Menheniott

Journal article  |  2019  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

The Mouse as a Model for Pulmonary Legionella Infection.

Garrett Z Ng, Anastasia Solomatina, Ian R van Driel, Elizabeth L Hartland

Book Chapter  |  2019  |  Methods in Molecular Biology

Infection of C57BL/6 mice with wild-type Legionella pneumophila typically results in very mild disease. However, in mice where the..

NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells

Le Son Tran, Darren Tran, Amanda De Paoli, Kimberley D'Costa, Sarah J Creed, Garrett Z Ng, Lena Le, Philip Sutton, J Silke, U Nachbur, Richard L Ferrero

Journal article  |  2018  |  Cellular Microbiology

Superoxide dismutase from Helicobacter pylori suppresses the production of pro-inflammatory cytokines during in vivo infection

Andrew Stent, Alison L Every, Yok T Chionh, Garrett Z Ng, Philip Sutton

Journal article  |  2018  |  Helicobacter

Reduced PU.1 expression underlies aberrant neutrophil maturation and function in beta-thalassemia mice and patients

Panjaree Siwaponanan, Jurre Ynze Siegers, Razi Ghazali, Thian Ng, Bradley McColl, Garrett Zhen-Wei Ng, Philip Sutton, Nancy Wang, Isabelle Ooi, Chayada Thiengtavor, Suthat Fucharoen, Pornthip Chaichompoo, Saovaros Svasti, Odilia Wijburg, Jim Vadolas

Journal article  |  2017  |  Blood

No evidence of a role for mitochondrial complex I in Helicobacter pylori pathogenesis

Garrett Z Ng, Bi-Xia Ke, Adrienne Laskowski, David R Thorburn, Philip Sutton

Journal article  |  2017  |  Helicobacter

Protease-activated Receptor 1 Plays a Proinflammatory Role in Colitis by Promoting Th17-related Immunity

Muhammad A Saeed, Garrett Z Ng, Jan Dabritz, Josef Wagner, Louise Judd, Jia-Xi Han, Poshmaal Dhar, Carl D Kirkwood, Philip Sutton

Journal article  |  2017  |  Inflammatory Bowel Diseases

Mucin 1 protects against severe Streptococcus pneumoniae infection

Poshmaal Dhar, Garrett Z Ng, Eileen M Dunne, Philip Sutton

Journal article  |  2017  |  VIRULENCE

How host regulation of Helicobacter pylori-induced gastritis protects against peptic ulcer disease and gastric cancer

Poshmaal Dhar, Garrett Z Ng, Philip Sutton

Journal article  |  2016  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome

Garrett Z Ng, Trevelyan R Menheniott, Alison L Every, Andrew Stent, Louise M Judd, Yok Teng Chionh, Poshmaal Dhar, Jasper C Komen, Andrew S Giraud, Timothy C Wang, Michael A McGuckin, Philip Sutton

Journal article  |  2016  |  GUT

The MUC1 mucin specifically inhibits activation of the NLRP3 inflammasome

GZ Ng, P Sutton

Journal article  |  2016  |  GENES AND IMMUNITY

Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression

Trevelyan R Menheniott, Louise O'Connor, Yok Teng Chionh, Jan Daebritz, Michelle Scurr, Benjamin N Rollo, Garrett Z Ng, Shelley Jacobs, Angelique Catubig, Bayzar Kurklu, Stephen Mercer, Toshinari Minamoto, David E Ong, Richard L Ferrero, James G Fox, Timothy C Wang, Philip Sutton, Louise M Judd, Andrew S Giraud

Journal article  |  2016  |  JOURNAL OF CLINICAL INVESTIGATION

Heat shock protein complex vaccines induce antibodies against Neisseria meningitidis via a MyD88-independent mechanism

Jia Xi Han, Garrett Z Ng, Paola Cecchini, Yok Teng Chionh, Muhammad A Saeed, Lisbeth M Naess, Michael Joachim, Lucy E Blandford, Richard A Strugnell, Camilo A Colaco, Philip Sutton

Journal article  |  2016  |  VACCINE

Activation of TRIF-dependent and independent immune responses by neisserial heat shock protein complex vaccines

Garrett Z Ng, Jia-Xi Han, Camilo A Colaco, Philip Sutton

Journal article  |  2016  |  HUMAN VACCINES & IMMUNOTHERAPEUTICS

An optimised perfusion technique for extracting murine gastric leukocytes

Garrett Z Ng, Philip Sutton

Journal article  |  2015  |  JOURNAL OF IMMUNOLOGICAL METHODS

Protease-activated receptor 1 suppresses Helicobacter pylori gastritis via the inhibition of macrophage cytokine secretion and interferon regulatory factor 5

Y-T Chionh, GZ Ng, L Ong, A Arulmuruganar, A Stent, MA Saeed, JLK Wee, P Sutton

Journal article  |  2015  |  MUCOSAL IMMUNOLOGY

Heat shock protein complex vaccination induces protection against Helicobacter pylori without exogenous adjuvant

Yok Teng Chionh, Arthi Arulmuruganar, Elena Venditti, Garrett Z Ng, Jia-Xi Han, Claire Entwisle, Ching-Seng Ang, Camilo A Colaco, Shaun McNulty, Philip Sutton

Journal article  |  2014  |  Vaccine

Vaccine-Mediated Protection against Helicobacter pylori is not Associated with Increased Salivary Cytokine or Mucin Expression

Garrett Z Ng, Yok-Teng Chionh, Philip Sutton

Journal article  |  2014  |  Helicobacter

Helicobacter pylori thiolperoxidase as a protective antigen in single- and multi-component vaccines

Andrew Stent, Alison L Every, Garrett Z Ng, Yok T Chionh, Lynette S Ong, Stirling J Edwards, Philip Sutton

Journal article  |  2012  |  Vaccine

Localized Suppression of Inflammation at Sites of Helicobacter pylori Colonization

Alison L Every, Garrett Z Ng, Caroline D Skene, Stacey N Harbour, Anna K Walduck, Michael A McGuckin, Philip Sutton

Journal article  |  2011  |  Infection and Immunity

Evaluation of superoxide dismutase from Helicobacter pylori as a protective vaccine antigen

Alison L Every, Andrew Stent, Margaret B Moloney, Garrett Z Ng, Caroline D Skene, Stirling J Edwards, Philip Sutton

Journal article  |  2011  |  Vaccine

Increased Helicobacter felis colonization in male 129/Sv mice fails to suppress gastritis (vol 2, pg 358, 2011)

Garrett Z Ng, Alison L Every, Michael A McGuckin, Philip Sutton

Journal article  |  2011  |  Gut Microbes

Development of the pathologies associated with Helicobacter pylori infection, most seriously gastric adenocarcinoma, are a consequ..

Protease-Activated Receptor-1 Down-regulates the Murine Inflammatory and Humoral Response to Helicobacter pylori

Janet LK Wee, Yok-Teng Chionh, Garrett Z Ng, Stacey N Harbour, Cody Allison, Charles N Pagel, Eleanor J Mackie, Hazel M Mitchell, Richard L Ferrero, Philip Sutton

Journal article  |  2010  |  Gastroenterology

M-Cell Targeting of Whole Killed Bacteria Induces Protective Immunity against Gastrointestinal Pathogens

Yok-Teng Chionh, Janet LK Wee, Alison L Every, Garrett Z Ng, Philip Sutton

Journal article  |  2009  |  Infection and Immunity