Christopher Armstrong

Systematic Review of NMR-Based Metabolomics Practices in Human Disease Research

Katherine Huang, Natalie Thomas, Paul R Gooley, Christopher W Armstrong

Journal article  |  2022  |  METABOLITES

Nuclear magnetic resonance (NMR) spectroscopy is one of the principal analytical techniques for metabolomics. It has the advantage..

The underlying sex differences in neuroendocrine adaptations relevant to Myalgic Encephalomyelitis Chronic Fatigue Syndrome

Natalie Thomas, Caroline Gurvich, Katherine Huang, Paul R Gooley, Christopher W Armstrong

Journal article  |  2022  |  FRONTIERS IN NEUROENDOCRINOLOGY

INTRODUCTION: Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) is a complex multisystem disease characterised by sever..

A network meta-analysis of stress mediators in suicide behaviour

Natalie Thomas, Christopher W Armstrong, Abdul-Rahman Hudaib, Jayashri Kulkarni, Caroline Gurvich

Journal article  |  2021  |  FRONTIERS IN NEUROENDOCRINOLOGY

UNLABELLED: Stress homeostatic mediators are the most consistently anomalous biomarkers observed in suicide and may therefore poin..

Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases

Neil R McGregor, Christopher W Armstrong, Donald P Lewis, Paul R Gooley

Journal article  |  2019  |  DIAGNOSTICS

Post-exertional malaise (PEM) is a cardinal predictive symptom in the definition of Myalgic Encephalomyelitis/Chronic Fatigue Synd..

CD24 Expression and B Cell Maturation Shows a Novel Link With Energy Metabolism: Potential Implications for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Fane FK Mensah, Christopher W Armstrong, Venkat Reddy, Amolak S Bansal, Saul Berkovitz, Maria J Leandro, Geraldine Cambridge

Journal article  |  2018  |  FRONTIERS IN IMMUNOLOGY

CD24 expression on pro-B cells plays a role in B cell selection and development in the bone marrow. We previously detected higher ..

The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome

Christopher W Armstrong, Neil R McGregor, Donald P Lewis, Henry L Butt, Paul R Gooley

Journal article  |  2017  |  Metabolomics

Introduction: The human gut microbiota has the ability to modulate host metabolism. Metabolic profiling of the microbiota and the ..

Widespread pain and altered renal function in ME/CFS patients

Neil R McGregor, Christopher W Armstrong, Donald P Lewis, Henry L Butt, Paul R Gooley

Journal article  |  2016  |  FATIGUE-BIOMEDICINE HEALTH AND BEHAVIOR

Background: Widespread pain is noted in many patients with chronic fatigue syndrome (ME/CFS), fibromyalgia and temporomandibular d..

Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients

Christopher W Armstrong, Neil R McGregor, Donald P Lewis, Henry L Butt, Paul R Gooley

Journal article  |  2015  |  METABOLOMICS

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating long-term multisystem disorder with a central and in..

Metabolism in Chronic Fatigue Syndrome

Christopher W Armstrong, Neil R McGregor, Henry L Butt, Paul R Gooley

Book Chapter  |  2014  |  Advances in Clinical Chemistry

Chronic fatigue syndrome (CFS) is a poorly understood condition that presents as long-term physical and mental fatigue with associ..

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome

Christopher W Armstrong, Neil R McGregor, John R Sheedy, Ian Buttfield, Henry L Butt, Paul R Gooley

Journal article  |  2012  |  CLINICA CHIMICA ACTA

Chronic fatigue syndrome (CFS) is a debilitating multisystem disorder characterised by long-term fatigue with a variety of other s..