Zhi Ling Teo

Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade

Imran G House, Peter Savas, Junyun Lai, Amanda XY Chen, Amanda J Oliver, Zhi L Teo, Kirsten L Todd, Melissa A Henderson, Lauren Giuffrida, Emma V Petley, Kevin Sek, Sherly Mardiana, Tuba N Gide, Camelia Quek, Richard A Scolyer, Georgina V Long, James S Wilmott, Sherene Loi, Phillip K Darcy, Paul A Beavis

Journal article  |  2020  |  Clinical Cancer Research

PURPOSE: Response rates to immune checkpoint blockade (ICB; anti-PD-1/anti-CTLA-4) correlate with the extent of tumor immune infil..

Characterization of high TIL breast cancers reveals a prognostic and functionally distinct tissue-resident memory subpopulation

P Savas, B Virassamy, C Ye, A Salim, CP Mintoff, F Caramia, R Salgado, ZL Teo, S Dushyanthen, A Byrne, SJ Luen, SB Fox, TP Speed, LK Mackay, PJ Neeson, S Loi

Conference Proceedings  |  2019  |  Poster Discussion Abstracts

Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

Peter Savas, Balaji Virassamy, Chengzhong Ye, Agus Salim, Christopher P Mintoff, Franco Caramia, Roberto Salgado, David J Byrne, Zhi L Teo, Sathana Dushyanthen, Ann Byrne, Lironne Wein, Stephen J Luen, Catherine Poliness, Sophie S Nightingale, Anita S Skandarajah, David E Gyorki, Chantel M Thornton, Paul A Beavis, Stephen B Fox, et al.

Journal article  |  2018  |  Nature Medicine

Is RNASEL:p.Glu265*a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

Tu Nguyen-Dumont, Zhi L Teo, Fleur Hammet, Alexis Roberge, Maryam Mahmoodi, Helen Tsimiklis, Daniel J Park, Bernard J Pope, Andrew Lonie, Miroslav K Kapuscinski, Khalid Mahmood, David E Goldgar, Graham G Giles, Ingrid Winship, John L Hopper, Melissa C Southey

Journal article  |  2018  |  BMC Cancer

Combined CDK4/6 and PI3K alpha Inhibition Is Synergistic and Immunogenic in Triple-Negative Breast Cancer

Zhi Ling Teo, Stephanie Versaci, Sathana Dushyanthen, Franco Caramia, Peter Savas, Chris P Mintoff, Magnus Zethoven, Balaji Virassamy, Stephen J Luen, Grant A McArthur, Wayne A Phillips, Phillip K Darcy, Sherene Loi

Journal article  |  2017  |  Cancer Research

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

Sathana Dushyanthen, Zhi Ling Teo, Franco Caramia, Peter Savas, Christopher P Mintoff, Balaji Virassamy, Melissa A Henderson, Stephen J Luen, Mariam Mansour, Michael H Kershaw, Joseph A Trapani, Paul J Neeson, Roberto Salgado, Grant A McArthur, Justin M Balko, Paul A Beavis, Phillip K Darcy, Sherene Loi

Journal article  |  2017  |  Nature Communications

Advancing Immunotherapy in Metastatic Breast Cancer

Mariam Mansour, Zhi Ling Teo, Stephen J Luen, Sherene Loi

Journal article  |  2017  |  Current Treatment Options in Oncology

Gene expression analysis: Current methods

ZL Teo, P Savas, S Loi

Book Chapter  |  2017

Gene expression analysis: Applications

P Savas, ZL Teo, S Loi

Book Chapter  |  2017

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Melissa C Southey, David E Goldgar, Robert Winqvist, Katri Pylkas, Fergus Couch, Marc Tischkowitz, William D Foulkes, Joe Dennis, Kyriaki Michailidou, Elizabeth J van Rensburg, Tuomas Heikkinen, Heli Nevanlinna, John L Hopper, Thilo Doerk, Kathleen BM Claes, Jorge Reis-Filho, Zhi Ling Teo, Paolo Radice, Irene Catucci, Paolo Peterlongo, et al.

Journal article  |  2016  |  Journal of Medical Genetics

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE"

Peter Savas, Zhi Ling Teo, Christophe Lefevre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi

Journal article  |  2016  |  PLOS Medicine

A community-based model of rapid autopsy in end-stage cancer patients

Kathryn Alsop, Heather Thorne, Shahneen Sandhu, Anne Hamilton, Christopher Mintoff, Elizabeth Christie, Odette Spruyt, Scott Williams, Orla McNally, Linda Mileshkin, Sumitra Ananda, Julene Hallo, Sherene Loi, Clare Scott, Peter Savas, Lisa Devereux, Patricia O'Brien, Sameera Gunawardena, Clare Hampson, Kate Strachan, et al.

Journal article  |  2016  |  Nature Biotechnology

Molecular segmentation of luminal breast: Reality in 2015?

Zhi Ling Teo, Sherene Loi

Journal article  |  2015  |  The Breast

Relevance of tumor-infiltrating lymphocytes in breast cancer

Sathana Dushyanthen, Paul A Beavis, Peter Savas, Zhi Ling Teo, Chenhao Zhou, Mariam Mansour, Phillip K Darcy, Sherene Loi

Journal article  |  2015  |  BMC Medicine

Mutation screening of PALB2 in clinically ascertained families from the Breast Cancer Family Registry

Nguyen-Dumont Tu, Fleur Hammet, Maryam Mahmoodi, Helen Tsimiklis, Zhi L Teo, Roger Li, Bernard J Pope, Mary Beth Terry, Saundra S Buys, Mary Daly, John L Hopper, Ingrid Winship, David E Goldgar, Daniel J Park, Melissa C Southey

Journal article  |  2015  |  Breast Cancer Research and Treatment

Oncogene addiction and immunity: clinical implications of tumour infiltrating lymphocytes in breast cancers overexpressing the HER2/neu oncogene

Peter Savas, Franco Caramia, Zhi Ling Teo, Sherene Loi

Journal article  |  2014  |  Current Opinion in Oncology

Breast-Cancer Risk in Families with Mutations in PALB2

AC Antoniou, S Casadei, T Heikkinen, D Barrowdale, K Pylkaes, J Roberts, A Lee, D Subramanian, K De Leeneer, F Fostira, E Tomiak, SL Neuhausen, ZL Teo, S Khan, K Aittomaeki, JS Moilanen, C Turnbull, S Seal, A Mannermaa, A Kallioniemi, et al.

Journal article  |  2014  |  New England Journal of Medicine

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation

Zhi Ling Teo, Lachlan McQueen-Miscamble, Kirsty Turner, Gemma Martinez, Bhavani Madakashira, Shoukat Dedhar, Michael L Robinson, Robb U de Longh

Journal article  |  2014  |  EXPERIMENTAL EYE RESEARCH

The incidence of PALB2 c.3113G > A in women with a strong family history of breast and ovarian cancer attending familial cancer centres in Australia

Zhi L Teo, Sarah D Sawyer, Paul A James, Gillian Mitchell, Alison H Trainer, Geoffrey J Lindeman, Kylie Shackleton, Linda Cicciarelli, Melissa C Southey

Journal article  |  2013  |  FAMILIAL CANCER

Hi-Plex for high-throughput mutation screening: application to the breast cancer susceptibility gene PALB2

Nguyen-Dumont Tu, Zhi L Teo, Bernard J Pope, Fleur Hammet, Maryam Mahmoodi, Helen Tsimiklis, Nelly Sabbaghian, Marc Tischkowitz, William D Foulkes, Graham G Giles, John L Hopper, Melissa C Southey, Daniel J Park

Journal article  |  2013  |  BMC MEDICAL GENOMICS

Tumour morphology predicts PALB2 germline mutation status

ZL Teo, E Provenzano, GS Dite, DJ Park, C Apicella, SD Sawyer, PA James, G Mitchell, AH Trainer, GJ Lindeman, K Shackleton, L Cicciarelli, SS Buys, IL Andrulis, AM Mulligan, G Glendon, EM John, MB Terry, M Daly, FA Odefrey, et al.

Journal article  |  2013  |  BRITISH JOURNAL OF CANCER

Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families

Zhi L Teo, Daniel J Park, Elena Provenzano, Catherine A Chatfield, Fabrice A Odefrey, Nguyen-Dumont Tu, James G Dowty, John L Hopper, Ingrid Winship, David E Goldgar, Melissa C Southey

Journal article  |  2013  |  Breast Cancer Research

PALB2 and breast cancer: ready for clinical translation!

Melissa C Southey, Zhi L Teo, Ingrid Winship

Journal article  |  2013  |  Appl Clin Genet

For almost two decades, breast cancer clinical genetics has operated in an environment where a heritable cause of breast cancer su..

Are PALB2 mutations associated with increased risk of male breast cancer?

A Sauty de Chalon, Z Teo, DJ Park, FA Odefrey, JL Hopper, MC Southey

Journal article  |  2010  |  Breast Cancer Research and Treatment

A PALB2 mutation associated with high risk of breast cancer

Melissa C Southey, Zhi L Teo, James G Dowty, Fabrice A Odefrey, Daniel J Park, Marc Tischkowitz, Nelly Sabbaghian, Carmel Apicella, Graham B Byrnes, Ingrid Winship, Laura Baglietto, Graham G Giles, David E Goldgar, William D Foulkes, John L Hopper

Journal article  |  2010  |  Breast Cancer Research