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Dr

Sarah Russell

Honorary
The Sir Peter Maccallum Department of Oncology
science & technology
life sciences & biomedicine
animals
humans
mice
cell polarity
cell biology
immunology
biochemistry & molecular biology
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Dr

Sarah Russell

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Oncology
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Dr

Sarah Russell

 
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Projects

Displaying the 10 most recent projects from 17 for Sarah Russell.

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ELUCIDATING IMMUNE RESPONSES BY SINGLE CELL PEDIGREE AND TRACING ANALYSIS

To develop vaccines and to combat autoimmunity, we need to understand how initial immune activation influences the fate of immune cells and ..

2016 - 2020
Completed
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ESTABLISHMENT OF ACRF ADVANCED CENTRE FOR CANCER CELL ISOLATION AND IMAGING

2013 - 2020
Completed
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SPATIAL CONTROL OF SIGNALLING IN IMMUNITY AND CANCER

Major breakthroughs in cancer and autoimmunity require understanding the molecular basis of by which cell behaviour is controlled. We now kn..

2014 - 2016
Completed
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DECIPHERING THE ROLE OF SCRIBBLE IN DEVELOPMENT AND DISEASE

Scribble is a protein that controls the orientation and organization of all cells within our body. Mutations in the Scribble gene are found ..

2016 - 2016
Completed
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CHARACTERISATION OF A FEEDBACK LOOP IN T CELLS

T cells play a central role in the immune response. The primary event in T cell activation is the triggering of a specific T cell receptor (..

2013 - 2015
Completed
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ASYMMETRIC CELL DIVISION IN T CELL DEVELOPMENT: CONSEQUENCES FOR IMMUNITY AND CANCER

Human health depends upon the development of an immune system that can effectively control infection without damaging normal tissue. In this..

2012 - 2014
Completed
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THE ROLE OF AP2A2 IN SELF-RENEWAL OF HAEMATOPOIETIC AND LEUKEMIC STEM CELLS.

The daily replenishment of the blood system is dependent on the blood stem cell. A unique property of these stem cells is self-renewal where..

2011 - 2013
Completed
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The effect of competing signals on immune cell function

Following an infection, our immune system generates a large and diverse repertoire of cells required to mount and regulate an appropriate im..

2011 - 2013
Completed
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A new mechanism for determining cell fate and function in T cells

Immune reactions are mediated by the expansion of white blood cells, and the progeny of this expansion is steered down different development..

2008 - 2010
Completed
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TESTING THE ROLE OF CELL POLARITY DURING THYMOCYTE DEVELOPMENT

2007 - 2010
Completed

17

Projects

Project Types

17

Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works from 56 for Sarah Russell.

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Developing T cells form an immunological synapse for passage through the beta-selection checkpoint

Amr H Allam, Mirren Charnley, Kim Pham, Sarah M Russell

Journal article  |  2021  |  JOURNAL OF CELL BIOLOGY

The β-selection checkpoint of T cell development tests whether the cell has recombined its genomic DNA to produce a functional T c..

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Prevalence of dementia in the Torres Strait

Sarah G Russell, Rachel Quigley, Fintan Thompson, Betty Sagigi, Dina LoGiudice, Kate Smith, Nancy Pachana, Gavin Miller, Edward Strivens

Journal article  |  2020  |  AUSTRALASIAN JOURNAL ON AGEING

OBJECTIVE: To examine the prevalence of dementia and problems associated with ageing in the Torres Strait. METHODS: The study was ..

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Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 CD29/CD49fhi in mice

Genevieve Dall, Jessica Vieusseux, Yashar Seyed-Razavi, Nathan Godde, Mandy Ludford-Menting, Sarah M Russell, Alan Ashworth, Robin L Anderson, Gail P Risbridger, Mark Shackleton, Kara L Britt

Journal article  |  2020  |  BREAST CANCER RESEARCH AND TREATMENT

BACKGROUND: Breast cancer (BCa) mortality is decreasing with early detection and improvement in therapies. The incidence of BCa, h..

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Nanoscale magnetic imaging enabled by nitrogen vacancy centres in nanodiamonds labelled by iron-oxide nanoparticles

Martina Barbiero, Stefania Castelletto, Qiming Zhang, Ye Chen, Mirren Charnley, Sarah Russell, Min Gu

Journal article  |  2020  |  NANOSCALE

Nanodiamonds containing the nitrogen vacancy centre (NV) have a significant role in biosensing, bioimaging, drug delivery, and as ..

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A new role for Notch in the control of polarity and asymmetric cell division of developing T cells

Mirren Charnley, Mandy Ludford-Menting, Pham Kim, Sarah M Russell

Journal article  |  2020  |  JOURNAL OF CELL SCIENCE

A fundamental question in biology is how single cells can reliably produce progeny of different cell types. Notch signalling frequ..

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Estrogen receptor positive luminal progenitors the cancer cell origin for Estrogen receptor positive breast cancer

Genevieve Dall, Serene Yeow, Jessica Vieusseux, Yashar Seyed-Razavi, Nathan Godde, Mandy Ludford-Menting, Sarah M Russell, Alan Ashworth, Robin Anderson, Kelly Phillips, Gail Risbridger, Mark Shackleton, Kara Britt

Conference Proceedings  |  2019  |  Oncology Abstracts

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An integrated transcriptional switch at the beta-selection checkpoint determines T cell survival, development and leukaemogenesis

Anchi S Chann, Sarah M Russell

Journal article  |  2019  |  BIOCHEMICAL SOCIETY TRANSACTIONS

In T cell development, a pivotal decision-making stage, termed β-selection, integrates a TCRβ checkpoint to coordinate survival, p..

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Developing T cells form an immunological synapse for passage through the β−selection checkpoint

Amr Allam, Mirren Charnley, Kim Pham, Sarah Russell

Journal article  |  2019

The β-selection checkpoint of T cell development tests whether the cell has recombined its genomic DNA to produce a functional T C..

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Maps of variability in cell lineage trees

Damien Hicks, Terence Speed, Mohammed Yassin, Sarah Russell

Journal article  |  2019  |  PLoS Computational Biology

New approaches to lineage tracking allow the study of cell differentiation over many generations of cells during development in mu..

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Context-Specific Mechanisms of Cell Polarity Regulation

Amr H Allam, Mirren Charnley, Sarah M Russell

Journal article  |  2018  |  JOURNAL OF MOLECULAR BIOLOGY

Cell polarity is an essential process shared by almost all animal tissues. Moreover, cell polarity enables cells to sense and resp..

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Scholarly Works

Keyword Analysis

Expanding Knowledge
Biochemistry and Cell Biology
Immunology
Clinical Health
Genetics
Oncology and Carcinogenesis
Cardiovascular Medicine and Haematology
Applied Computing
Biomedical Engineering
Analytical Chemistry

Honours, Awards and Fellowships

1999

Wellcome Senior Research Fellowship
1996

R D Wright Postdoctoral Fellowship
1993

Fogarty Visiting Fellowship (USA)
1991

TSANZ President's Award

4

Awards

Credentials

Positions

Honorary

The Sir Peter Maccallum Department of Oncology

Honorary

Clinical Pathology

Education

PhD

University of Melbourne

Bachelor of Science (Hons)

University of Melbourne

Links