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Dr

Sarah Russell

Honorary
The Sir Peter Maccallum Department of Oncology
science & technology
life sciences & biomedicine
1.1 normal biological development and functioning
1 underpinning research
immunology
generic health relevance
cell biology
2.1 biological and endogenous factors
2 aetiology
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Dr

Sarah Russell

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Oncology
Sarah Russell's Profile Picture
Dr

Sarah Russell

 
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Projects

Displaying the 10 most recent projects from 17 for Sarah Russell.

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ELUCIDATING IMMUNE RESPONSES BY SINGLE CELL PEDIGREE AND TRACING ANALYSIS

To develop vaccines and to combat autoimmunity, we need to understand how initial immune activation influences the fate of immune cells and ..

2016 - 2020
Completed
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ESTABLISHMENT OF ACRF ADVANCED CENTRE FOR CANCER CELL ISOLATION AND IMAGING

2013 - 2020
Completed
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SPATIAL CONTROL OF SIGNALLING IN IMMUNITY AND CANCER

Major breakthroughs in cancer and autoimmunity require understanding the molecular basis of by which cell behaviour is controlled. We now kn..

2014 - 2016
Completed
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DECIPHERING THE ROLE OF SCRIBBLE IN DEVELOPMENT AND DISEASE

Scribble is a protein that controls the orientation and organization of all cells within our body. Mutations in the Scribble gene are found ..

2016 - 2016
Completed
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CHARACTERISATION OF A FEEDBACK LOOP IN T CELLS

T cells play a central role in the immune response. The primary event in T cell activation is the triggering of a specific T cell receptor (..

2013 - 2015
Completed
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ASYMMETRIC CELL DIVISION IN T CELL DEVELOPMENT: CONSEQUENCES FOR IMMUNITY AND CANCER

Human health depends upon the development of an immune system that can effectively control infection without damaging normal tissue. In this..

2012 - 2014
Completed
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THE ROLE OF AP2A2 IN SELF-RENEWAL OF HAEMATOPOIETIC AND LEUKEMIC STEM CELLS.

The daily replenishment of the blood system is dependent on the blood stem cell. A unique property of these stem cells is self-renewal where..

2011 - 2013
Completed
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The effect of competing signals on immune cell function

Following an infection, our immune system generates a large and diverse repertoire of cells required to mount and regulate an appropriate im..

2011 - 2013
Completed
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A new mechanism for determining cell fate and function in T cells

Immune reactions are mediated by the expansion of white blood cells, and the progeny of this expansion is steered down different development..

2008 - 2010
Completed
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TESTING THE ROLE OF CELL POLARITY DURING THYMOCYTE DEVELOPMENT

2007 - 2010
Completed

17

Projects

Project Types

17

Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works from 104 for Sarah Russell.

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E-cadherin in developing murine T cells controls spindle alignment and progression through β-selection.

Mirren Charnley, Amr H Allam, Lucas M Newton, Patrick O Humbert, Sarah M Russell

Journal article  |  2023  |  Sci Adv

A critical stage of T cell development is β-selection; at this stage, the T cell receptor β (TCRβ) chain is generated, and the dev..

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Scribble and E-cadherin cooperate to control symmetric daughter cell positioning by multiple mechanisms

Anchi S Chann, Ye Chen, Tanja Kinwel, Patrick O Humbert, Sarah M Russell

Journal article  |  2023  |  JOURNAL OF CELL SCIENCE

The fate of the two daughter cells is intimately connected to their positioning, which is in turn regulated by cell junction remod..

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Stepwise progression of β-selection during T cell development involves histone deacetylation.

Anchi S Chann, Mirren Charnley, Lucas M Newton, Andrea Newbold, Florian Wiede, Tony Tiganis, Patrick O Humbert, Ricky W Johnstone, Sarah M Russell

Journal article  |  2023  |  Life Sci Alliance

During T cell development, the first step in creating a unique T cell receptor (TCR) is genetic recombination of the TCRβ chain. T..

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Establishing a multiplex imaging panel to study T cell development in the thymus in mouse.

Amr H Allam, Sarah M Russell

Journal article  |  2022  |  STAR Protoc

Multiplexed immunohistochemistry enables analysis of cellular and signaling events in the context of an intact organ. Here, we des..

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Developing T cells form an immunological synapse for passage through the beta-selection checkpoint

Amr H Allam, Mirren Charnley, Kim Pham, Sarah M Russell

Journal article  |  2021  |  JOURNAL OF CELL BIOLOGY

The β-selection checkpoint of T cell development tests whether the cell has recombined its genomic DNA to produce a functional T c..

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Prevalence of dementia in the Torres Strait

Sarah G Russell, Rachel Quigley, Fintan Thompson, Betty Sagigi, Dina LoGiudice, Kate Smith, Nancy Pachana, Gavin Miller, Edward Strivens

Journal article  |  2020  |  AUSTRALASIAN JOURNAL ON AGEING

OBJECTIVE: To examine the prevalence of dementia and problems associated with ageing in the Torres Strait. METHODS: The study was ..

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Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 CD29/CD49fhi in mice

Genevieve Dall, Jessica Vieusseux, Yashar Seyed-Razavi, Nathan Godde, Mandy Ludford-Menting, Sarah M Russell, Alan Ashworth, Robin L Anderson, Gail P Risbridger, Mark Shackleton, Kara L Britt

Journal article  |  2020  |  BREAST CANCER RESEARCH AND TREATMENT

BACKGROUND: Breast cancer (BCa) mortality is decreasing with early detection and improvement in therapies. The incidence of BCa, h..

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Nanoscale magnetic imaging enabled by nitrogen vacancy centres in nanodiamonds labelled by iron-oxide nanoparticles

Martina Barbiero, Stefania Castelletto, Qiming Zhang, Ye Chen, Mirren Charnley, Sarah Russell, Min Gu

Journal article  |  2020  |  NANOSCALE

Nanodiamonds containing the nitrogen vacancy centre (NV) have a significant role in biosensing, bioimaging, drug delivery, and as ..

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A new role for Notch in the control of polarity and asymmetric cell division of developing T cells

Mirren Charnley, Mandy Ludford-Menting, Pham Kim, Sarah M Russell

Journal article  |  2020  |  JOURNAL OF CELL SCIENCE

A fundamental question in biology is how single cells can reliably produce progeny of different cell types. Notch signalling frequ..

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Estrogen receptor positive luminal progenitors the cancer cell origin for Estrogen receptor positive breast cancer

Genevieve Dall, Serene Yeow, Jessica Vieusseux, Yashar Seyed-Razavi, Nathan Godde, Mandy Ludford-Menting, Sarah M Russell, Alan Ashworth, Robin Anderson, Kelly Phillips, Gail Risbridger, Mark Shackleton, Kara Britt

Conference Proceedings  |  2019  |  Oncology Abstracts

104

Scholarly Works

Keyword Analysis

Expanding Knowledge
Biochemistry and Cell Biology
Immunology
Clinical Health
Oncology and Carcinogenesis
Genetics
Cardiovascular Medicine and Haematology
Applied Computing
Biomedical Engineering
Analytical Chemistry

Honours, Awards and Fellowships

1999

Wellcome Senior Research Fellowship
1996

R D Wright Postdoctoral Fellowship
1993

Fogarty Visiting Fellowship (USA)
1991

TSANZ President's Award

4

Awards

Credentials

Positions

Honorary

The Sir Peter Maccallum Department of Oncology

Education

PhD

University of Melbourne

Bachelor of Science (Hons)

University of Melbourne

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