Clare Parish

Ischemic Injury Does Not Stimulate Striatal Neuron Replacement Even during Periods of Active Striatal Neurogenesis.

Charlotte M Ermine, Jordan L Wright, Davor Stanic, Clare L Parish, Lachlan H Thompson

Journal article  |  2020  |  iScience

Ischemic damage to the adult rodent forebrain has been widely used as a model system to study injury-induced neurogenesis, resulti..

Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease

Carlos W Gantner, Isabelle R de Luzy, Jessica A Kauhausen, Niamh Moriarty, Jonathan C Niclis, Christopher R Bye, Vanessa Penna, Cameron PJ Hunt, Charlotte M Ermine, Colin W Pouton, Deniz Kirik, Lachlan H Thompson, Clare L Parish

Journal article  |  2020  |  Cell Stem Cell

Dopaminergic neurons (DAns), generated from human pluripotent stem cells (hPSCs), are capable of functionally integrating followin..

The application of human pluripotent stem cells to model the neuronal and glial components of neurodevelopmental disorders

KM Lee, ZH Hawi, HC Parkington, CL Parish, PV Kumar, JM Polo, MA Bellgrove, J Tong

Journal article  |  2020  |  Molecular Psychiatry

Cellular models of neurodevelopmental disorders provide a valuable experimental system to uncover disease mechanisms and novel the..

Biomimetic Materials and Their Utility in Modeling the 3-Dimensional Neural Environment

Arianna Cembran, Kiara F Bruggeman, Richard J Williams, Clare L Parish, David R Nisbet

Journal article  |  2020  |  iScience

The brain is a complex 3-dimensional structure, the organization of which provides a local environment that directly influences th..

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

Charlotte M Ermine, Fahad Somaa, Ting-Yi Wang, Brett J Kagan, Clare L Parish, Lachlan H Thompson

Journal article  |  2019  |  Frontiers in Cellular Neuroscience

Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease

Isabelle R de Luzy, Jonathan C Niclis, Carlos W Gantner, Jessica A Kauhausen, Cameron PJ Hunt, Charlotte Ermine, Colin W Pouton, Lachlan H Thompson, Clare L Parish

Journal article  |  2019  |  The Journal of Neuroscience

Human pluripotent stem cells (hPSCs) are a promising resource for the replacement of degenerated ventral midbrain dopaminergic (vm..

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

Christopher R Bye, Vanessa Penna, Isabelle R de Luzy, Carlos W Gantner, Cameron PJ Hunt, Lachlan H Thompson, Clare L Parish

Journal article  |  2019  |  Stem Cell Reports

Human pluripotent stem cells are a valuable resource for transplantation, yet our ability to profile xenografts is largely limited..

Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy

Ibrahim Javed, Guotao Peng, Yanting Xing, Tianyu Yu, Mei Zhao, Aleksandr Kakinen, Ava Faridi, Clare L Parish, Feng Ding, Thomas P Davis, Pu Chun Ke, Sijie Lin

Journal article  |  2019  |  Nature Communications

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins

Christopher R Bye, Valeria Rytova, Walaa F Alsanie, Clare L Parish, Lachlan H Thompson

Journal article  |  2019  |  The Journal of Neuroscience

The growth of axons corresponding to different neuronal subtypes is governed by unique expression profiles of molecules on the gro..

Harnessing stem cells and biomaterials to promote neural repair

KF Bruggeman, N Moriarty, E Dowd, DR Nisbet, CL Parish

Journal article  |  2019  |  British Journal of Pharmacology

Primary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterials

Niamh Moriarty, Clare L Parish, Eilis Dowd

Journal article  |  2019  |  European Journal of Neuroscience

Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian family

Janette Tong, Kyung Min Lee, Xiaodong Liu, Christian M Nefzger, Prasidhee Vijayakumar, Ziarih Hawi, Ken C Pang, Clare L Parish, Jose M Polo, Mark A Bellgrove

Journal article  |  2019  |  Stem Cell Research

Local Injection of Endothelin-1 in the Early Neonatal Rat Brain Models Ischemic Damage Associated with Motor Impairment and Diffuse Loss in Brain Volume

Jordan L Wright, Hannah X Chu, Brett J Kagan, Charlotte M Ermine, Jessica A Kauhausen, Clare L Parish, Christopher G Sobey, Lachlan H Thompson

Journal article  |  2018  |  Neuroscience

Shear Containment of BDNF within Molecular Hydrogels Promotes Human Stem Cell Engraftment and Pos infarc ion Remodeling in Stroke

DR Nisbet, TY Wang, KF Bruggeman, JC Niclis, FA Somaa, V Penna, CPJ Hunt, Y Wang, JA Kauhausen, RJ Williams, LH Thompson, CL Parish

Journal article  |  2018  |  Advanced Biosystems

Modelling the dopamine and noradrenergic cell loss that occurs in Parkinson's disease and the impact on hippocampal neurogenesis

Charlotte M Ermine, Jordan L Wright, Stefano Frausin, Jessica A Kauhausen, Clare L Parish, Davor Stanic, Lachlan H Thompson

Journal article  |  2018  |  Hippocampus

Using minimalist self-assembling peptides as hierarchical scaffolds to stabilise growth factors and promote stem cell integration in the injured brain

AL Rodriguez, KF Bruggeman, Y Wang, TY Wang, RJ Williams, CL Parish, DR Nisbet

Journal article  |  2018  |  Journal of Tissue Engineering and Regenerative Medicine

BIOMATERIALS SUPPORT THE INTEGRATION OF HUMAN EMBRYONIC STEM CELL-DERIVED CORTICAL GRAFTS TO PROMOTE FUNCTIONAL REPAIR IN A MODEL OF FOCAL ISCHEMIA

FA Somaa, TY Wang, JC Niclis, KF Bruggman, JA Kauhausen, H Guo, S McDougall, RJ Williams, DR Nisbet, LH Thompson, CL Parish

Conference Proceedings  |  2018  |  JOURNAL OF GENE MEDICINE

COMPARISON OF THERAPEUTIC EFFICACY OF NEURAL PROGENITORS TO UMBILICAL CORD STEM CELLS IN A RODENT MODEL OF NEONATAL BRAIN DAMAGE

Brett J Kagan, Laura J Tatnell, Jennifer Durnall, Pei Tian, Ngaire Elwood, Clare L Parish, Lachlan H Thompson

Conference Proceedings  |  2018  |  JOURNAL OF GENE MEDICINE

Specification of murine ground state pluripotent stem cells to regional neuronal populations

Walaa F Alsanie, Jonathan C Niclis, Cameron P Hunt, Isabelle R De Luzy, Vanessa Penna, Christopher R Bye, Colin W Pouton, John Haynes, Jaber Firas, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  Scientific Reports

Temporally controlled growth factor delivery from a self-assembling peptide hydrogel and electrospun nanofibre composite scaffold

Kiara F Bruggeman, Yi Wang, Francesca L Maclean, Clare L Parish, Richard J Williams, David R Nisbet

Journal article  |  2017  |  Nanoscale

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

Jonathan C Niclis, Carlos W Gantner, Cameron PJ Hunt, Jessica A Kauhausen, Jennifer C Durnall, John M Haynes, Colin W Pouton, Clare L Parish, Lachlan H Thompson

Journal article  |  2017  |  Stem Cell Reports

Homophilic binding of the neural cell adhesion molecule CHL1 regulates development of ventral midbrain dopaminergic pathways

WF Alsanie, V Penna, M Schachner, LH Thompson, CL Parish

Journal article  |  2017  |  Scientific Reports

Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke

Fahad A Somaa, Ting-Yi Wang, Jonathan C Niclis, Kiara F Bruggeman, Jessica A Kauhausen, Haoyao Guo, Stuart McDougall, Richard J Williams, David R Nisbet, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  Cell Reports

Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived from Human Induced Pluripotent Stem Cells After Intracerebral Transplantation

Jonathan C Niclis, Christopher Turner, Jennifer Durnall, Stuart McDougal, Jessica A Kauhausen, Bryan Leaw, Mirella Dottori, Clare L Parish, Lachlan H Thompson

Journal article  |  2017  |  STEM CELLS Translational Medicine

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

Yasmin M Ramdzan, Mikhail M Trubetskov, Angelique R Ormsby, Estella A Newcombe, Xiaojing Sui, Mark J Tobin, Marie N Bongiovanni, Sally L Gras, Grant Dewson, Jason ML Miller, Steven Finkbeiner, Nagaraj S Moily, Jonathan Niclis, Clare L Parish, Anthony W Purcell, Michael J Baker, Jacqueline A Wilce, Saboora Waris, Diana Stojanovski, Till Bocking, et al.

Journal article  |  2017  |  Cell reports

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents

Jonathan C Niclis, Carlos W Gantner, Walaa F Alsanie, Stuart J McDougall, Chris R Bye, Andrew G Elefanty, Edouard G Stanley, John M Haynes, Colin W Pouton, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  STEM CELLS Translational Medicine

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

Jonathan C Niclis, Carlos W Gantner, Walaa F Alsanie, Stuart J McDougall, Chris R Bye, Andrew G Elefanty, Edouard G Stanley, John M Haynes, Colin W Pouton, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  Stem Cells Transl Med

Recent studies have shown evidence for the functional integration of human pluripotent stem cell (hPSC)-derived ventral midbrain d..

Temporally controlled release of multiple growth factors from a self-assembling peptide hydrogel

Kiara F Bruggeman, Alexandra L Rodriguez, Clare L Parish, Richard J Williams, David R Nisbet

Journal article  |  2016  |  Nanotechnology

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

Tim Kao, Tanya Labonne, Jonathan C Niclis, Ritu Chaurasia, Zerina Lokmic, Elizabeth Qian, Freya F Bruveris, Sara E Howden, Ali Motazedian, Jacqueline V Schiesser, Magdaline Costa, Koula Sourris, Elizabeth Ng, David Anderson, Antonietta Giudice, Peter Farlie, Michael Cheung, Shireen R Lamande, Anthony J Penington, Clare L Parish, et al.

Journal article  |  2016  |  Stem Cell Reports

Over-Expression of Meteorin Drives Gliogenesis Following Striatal Injury

Jordan L Wright, Charlotte M Ermine, Jesper R Jorgensen, Clare L Parish, Lachlan H Thompson

Journal article  |  2016  |  Frontiers in Cellular Neuroscience

Combined immunohistochemical and retrograde tracing reveals little evidence of innervation of the rat dentate gyrus by midbrain dopamine neurons

CM Ermine, JL Wright, CL Parish, D Stanic, LH Thompson

Journal article  |  2016  |  Frontiers in Biology

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors

Eva Hedlund, Laure Belnoue, Spyridon Theofilopoulos, Carmen Salto, Chris Bye, Clare Parish, Qiaolin Deng, Banafsheh Kadkhodaei, Johan Ericson, Ernest Arenas, Thomas Perlmann, Andras Simon

Journal article  |  2016  |  Scientific Reports

Tailoring minimalist self-assembling peptides for localized viral vector gene delivery

Alexandra L Rodriguez, Ting-Yi Wang, Kiara F Bruggeman, Rui Li, Richard J Williams, Clare L Parish, David R Nisbet

Journal article  |  2016  |  Nano Research

Integrating Biomaterials and Stem Cells for Neural Regeneration

Francesca L Maclean, Alexandra L Rodriguez, Clare L Parish, Richard J Williams, David R Nisbet

Journal article  |  2016  |  Stem Cells and Development

Functionalized composite scaffolds improve the engraftment of transplanted dopaminergic progenitors in a mouse model of Parkinson's disease

Ting-Yi Wang, Kiara F Bruggeman, Jessica A Kauhausen, Alexandra L Rodriguez, David R Nisbet, Clare L Parish

Journal article  |  2016  |  Biomaterials

Chondroitinase improves midbrain pathway reconstruction by transplanted dopamine progenitors in Parkinsonian mice

Jessica A Kauhausen, Lachlan H Thompson, Clare L Parish

Journal article  |  2015  |  Molecular and Cellular Neuroscience

14-3-3 zeta deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders

Xiangjun Xu, Emily J Jaehne, Zarina Greenberg, Peter McCarthy, Eiman Saleh, Clare L Parish, Daria Camera, Julian Heng, Matilda Haas, Bernhard T Baune, Udani Ratnayake, Maarten van den Buuse, Angel F Lopez, Hayley S Ramshaw, Quenten Schwarz

Journal article  |  2015  |  Scientific Reports

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

Kelan Chen, Jiang Hu, Darcy L Moore, Ruijie Liu, Sarah A Kessans, Kelsey Breslin, Isabelle S Lucet, Andrew Keniry, Huei San Leong, Clare L Parish, Douglas J Hilton, Richard JLF Lemmers, Silvere M van der Maarel, Peter E Czabotar, Renwick CJ Dobson, Matthew E Ritchie, Graham F Kay, James M Murphy, Marnie E Blewitt

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice

Fahad A Somaa, Christopher R Bye, Lachlan H Thompson, Clare L Parish

Journal article  |  2015  |  Experimental Neurology

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors

Chris R Bye, Marie E Jonsson, Anders Bjorklund, Clare L Parish, Lachlan H Thompson

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Motor and behavioral phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cells

Luning Jiang, Claire O'Leary, Hyun Ah Kim, Clare L Parish, Jim Massalas, John L Waddington, Michelle E Ehrlich, Guenter Schuetz, Ilse Gantois, Andrew J Lawrence, John Drago

Journal article  |  2015  |  Neurobiology of Disease

Characterisation of the stability and bio-functionality of tethered proteins on bioengineered scaffolds: Implications for stem cell biology and tissue repair

TY Wang, KAF Bruggeman, RK Sheean, DR Nisbet, CL Parish

Conference Proceedings  |  2015  |  IFMBE Proceedings

© Springer International Publishing Switzerland 2015. In the context of biological applications, the timely delivery of molecules ..

Diverse Roles for Wnt7a in Ventral Midbrain Neurogenesis and Dopaminergic Axon Morphogenesis

Chathurini V Fernando, Julianna Kele, Christopher R Bye, Jonathan C Niclis, Walaa Alsanie, Brette D Blakely, Jan Stenman, Brad J Turner, Clare L Parish

Journal article  |  2014  |  Stem Cells and Development

Functional Characterization of Friedreich Ataxia iPS-Derived Neuronal Progenitors and Their Integration in the Adult Brain

Matthew J Bird, Karina Needham, Ann E Frazier, Jorien van Rooijen, Jessie Leung, Shelley Hough, Mark Denham, Matthew E Thornton, Clare L Parish, Bryony A Nayagam, Martin Pera, David R Thorburn, Lachlan H Thompson, Mirella Dottori

Journal article  |  2014  |  PLoS One

3D Electrospun scaffolds promote a cytotrophic phenotype of cultured primary astrocytes

Chew L Lau, Michelle Kovacevic, Tine S Tingleff, John S Forsythe, Holly S Cate, Daniel Merlo, Cecilia Cederfur, Francesca L Maclean, Clare L Parish, Malcolm K Horne, David R Nisbet, Philip M Beart

Journal article  |  2014  |  Journal of Neurochemistry

Characterization of the Stability and Bio-functionality of Tethered Proteins on Bioengineered Scaffolds IMPLICATIONS FOR STEM CELL BIOLOGY AND TISSUE REPAIR

Ting-Yi Wang, Kiara AF Bruggeman, Rebecca K Sheean, Bradley J Turner, David R Nisbet, Clare L Parish

Journal article  |  2014  |  Journal of Biological Chemistry

Modulating Wnt signaling to improve cell replacement therapy for Parkinsons disease

Clare L Parish, Lachlan H Thompson

Journal article  |  2014  |  Journal of Molecular Cell Biology

Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells

Hyun Ah Kim, Luning Jiang, Heather Madsen, Clare L Parish, Jim Massalas, Arthur Smardencas, Claire O'Leary, Ilse Gantois, Colm O'Tuathaigh, John L Waddington, Michelle E Ehrlich, Andrew J Lawrence, John Drago

Journal article  |  2014  |  Neurobiology of Disease

In vivo assessment of grafted cortical neural progenitor cells and host response to functionalized self-assembling peptide hydrogels and the implications for tissue repair

AL Rodriguez, TY Wang, KF Bruggeman, CC Horgan, R Li, RJ Williams, CL Parish, DR Nisbet

Journal article  |  2014  |  J. Mater. Chem. B

Locomotor hyperactivity in 14-3-3 zeta KO mice is associated with dopamine transporter dysfunction

H Ramshaw, X Xu, EJ Jaehne, P McCarthy, Z Greenberg, E Saleh, B McClure, J Woodcock, S Kabbara, S Wiszniak, Ting-Yi Wang, C Parish, M van den Buuse, BT Baune, A Lopez, Q Schwarz

Journal article  |  2013  |  Translational Psychiatry

Developing stem cell-based therapies for neural repair

Clare L Parish, Lachlan H Thompson

Journal article  |  2013  |  Frontiers in Cellular Neuroscience

Improving cell based therapy for Parkinson's disease

CL Parish

Conference Proceedings  |  2013  |  JOURNAL OF MOLECULAR NEUROSCIENCE

A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYK

Michael M Halford, Maria L Macheda, Clare L Parish, Elena A Takano, Stephen Fox, Daniel Layton, Edouard Nice, Steven A Stacker

Journal article  |  2013  |  PLoS One

Ryk, a Receptor Regulating Wnt5a-Mediated Neurogenesis and Axon Morphogenesis of Ventral Midbrain Dopaminergic Neurons

Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Asheeta A Prasad, R Jeroen Pasterkamp, Maria L Macheda, Steven A Stacker, Clare L Parish

Journal article  |  2013  |  Stem Cells and Development

Cell intrinsic and extrinsic factors contribute to enhance the integration of neural transplants in Parkinsonian mice

CR Bye, JA Kauhausen, LH Thompson, CL Parish

Conference Proceedings  |  2013  |  JOURNAL OF NEUROCHEMISTRY

Transplantation of Fetal Midbrain Dopamine Progenitors into a Rodent Model of Parkinson's Disease

Lachlan H Thompson, Clare L Parish

Journal article  |  2013  |  Methods in Molecular Biology

Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice

Jessica Kauhausen, Lachlan H Thompson, Clare L Parish

Journal article  |  2013  |  Journal of Physiology

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

Diogo Ribeiro, Rocio Laguna Goya, Geeta Ravindran, Romina Vuono, Clare L Parish, Claire Foldi, Tobias Piroth, Shanzheng Yang, Malin Parmar, Guido Nikkhah, Jens Hjerling-Leffler, Olle Lindvall, Roger A Barker, Ernest Arenas

Journal article  |  2013  |  Neurobiology of Disease

Tuning the amino acid sequence of minimalist peptides to present biological signals via charge neutralised self assembly

Alexandra L Rodriguez, Clare L Parish, David R Nisbet, Richard J Williams

Journal article  |  2013  |  Soft Matter

Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffolds

Ting-Yi Wang, John S Forsythe, David R Nisbet, Clare L Parish

Journal article  |  2012  |  Biomaterials

Biofunctionalisation of polymeric scaffolds for neural tissue engineering

TY Wang, JS Forsythe, CL Parish, DR Nisbet

Journal article  |  2012  |  Journal of Biomaterials Applications

Lessons learnt from fetal transplantation for the use of pluripotent stem cells

CL Parish

Conference Proceedings  |  2012  |  JOURNAL OF NEUROCHEMISTRY

Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into Parkinsonian mice

Christopher R Bye, Lachlan H Thompson, Clare L Parish

Journal article  |  2012  |  Experimental Neurology

The human testis-determining factor SRY localizes in midbrain dopamine neurons and regulates multiple components of catecholamine synthesis and metabolism

Daniel P Czech, Joohyung Lee, Helena Sim, Clare L Parish, Eric Vilain, Vincent R Harley

Journal article  |  2012  |  Journal of Neurochemistry

SFRP1 and SFRP2 Dose-Dependently Regulate Midbrain Dopamine Neuron Development In Vivo and in Embryonic Stem Cells

Julianna Kele, Emma R Andersson, J Carlos Villaescusa, Lukas Cajanek, Clare L Parish, Sonia Bonilla, Enrique M Toledo, Vitezslav Bryja, Jeffrey S Rubin, Akihiko Shimono, Ernest Arenas

Journal article  |  2012  |  Stem Cells

Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation

Mark Denham, Clare L Parish, Bryan Leaw, Jordan Wright, Christopher A Reid, Steven Petrou, Mirella Dottori, Lachlan H Thompson

Journal article  |  2012  |  Frontiers in Cellular Neuroscience

The potential of stem cells and tissue engineered scaffolds for repair of the central nervous system

AL Rodriguez, DR Nisbet, CL Parish

Book Chapter  |  2012

WNTS IMPROVES CELL REPLACEMENT THERAPY IN PARKINSON'S DISEASE

CL Parish

Conference Proceedings  |  2011  |  JOURNAL OF NEUROCHEMISTRY

Development of an In Vitro Model to Evaluate the Regenerative Capacity of Adult Brain-Derived Tyrosine Hydroxylase-Expressing Dopaminergic Neurons

Shohreh Majd, Arthur Smardencas, Clare L Parish, John Drago

Journal article  |  2011  |  Neurochemical Research

Wnt5a Regulates Midbrain Dopaminergic Axon Growth and Guidance

Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Malcolm K Horne, Maria L Macheda, Steven A Stacker, Ernest Arenas, Clare L Parish

Journal article  |  2011  |  PLoS One

Cellular Up-regulation of Nedd4 Family Interacting Protein 1 (Ndfip1) using Low Levels of Bioactive Cobalt Complexes

Christine Schieber, Jason Howitt, Ulrich Putz, Jonathan M White, Clare L Parish, Paul S Donnelly, Seong-Seng Tan

Journal article  |  2011  |  Journal of Biological Chemistry

Functional Integration of Grafted Neural Stem Cell-Derived Dopaminergic Neurons Monitored by Optogenetics in an In Vitro Parkinson Model

Jan Tonnesen, Clare L Parish, Andreas T Sorensen, Angelica Andersson, Cecilia Lundberg, Karl Deisseroth, Ernest Arenas, Olle Lindvall, Merab Kokaia

Journal article  |  2011  |  PLoS ONE

CHRONIC COCAINE ADMINISTRATION REDUCES STRIATAL DOPAMINE TERMINAL DENSITY AND STRIATAL DOPAMINE RELEASE WHICH LEADS TO DRUG-SEEKING BEHAVIOUR

J Lee, CL Parish, D Tomas, MK Horne

Journal article  |  2011  |  Neuroscience

Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons

Tim D Aumann, Kate Egan, Jamie Lim, Wah C Boon, Chris R Bye, Hui K Chua, Natalija Baban, Clare L Parish, Larisa Bobrovskaya, Phillip Dickson, Malcolm K Horne

Journal article  |  2011  |  Journal of Neurochemistry

Creating a Ventral Midbrain Stem Cell Niche in an Animal Model for Parkinson's Disease

Chathurini V Fernando, David Moses, Clare L Parish, Doris Tomas, John Drago, Malcolm K Horne

Journal article  |  2010  |  Stem Cells and Development

Y WNT SIGNALING IMPROVES CELL REPLACEMENT THERAPY IN PARKINSON'S DISEASE

CL Parish

Conference Proceedings  |  2010  |  JOURNAL OF NEUROCHEMISTRY

A Small Synthetic Cripto Blocking Peptide Improves Neural Induction, Dopaminergic Differentiation, and Functional Integration of Mouse Embryonic Stem Cells in a Rat Model of Parkinson's Disease

Enza Lonardo, Clare L Parish, Salvatore Ponticelli, Daniela Marasco, Diogo Ribeiro, Menotti Ruvo, Sandro De Falco, Ernest Arenas, Gabriella Minchiotti

Journal article  |  2010  |  Stem Cells

Three-Dimensional Nanofibrous Scaffolds Incorporating Immobilized BDNF Promote Proliferation and Differentiation of Cortical Neural Stem Cells

Malcolm K Horne, David R Nisbet, John S Forsythe, Clare L Parish

Journal article  |  2010  |  Stem Cells and Development

Biomaterials for Brain Tissue Engineering

Jerani TS Pettikiriarachchi, Clare L Parish, Molly S Shoichet, John S Forsythe, David R Nisbet

Journal article  |  2010  |  Australian Journal of Chemistry

Wnt/beta-Catenin Signaling Blockade Promotes Neuronal Induction and Dopaminergic Differentiation in Embryonic Stem Cells

Lukas Cajanek, Diogo Ribeiro, Isabel Liste, Clare L Parish, Vitezslav Bryja, Ernest Arenas

Journal article  |  2009  |  Stem Cells

Enhanced dopaminergic differentiation of neural and embryonic stem cells by Wnt5a

Ernest Arenas, Clare Parish, Isabel Liste, Diogo Ribeiro, Emma Andersson, Carmen Salto, Carmen Ramirez, Vitezslav Bryja

Conference Proceedings  |  2009  |  HUMAN GENE THERAPY

Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem Cells

Paola Sacchetti, Kyle M Sousa, Anita C Hall, Isabel Liste, Knut R Steffensen, Spyridon Theofilopoulos, Clare L Parish, Carin Hazenberg, Lars Ahrlund-Richter, Outti Hovatta, Jan-Ake Gustafsson, Ernest Arenas

Journal article  |  2009  |  Cell Stem Cell

Dopamine D-2 Receptor Knockout Mice Develop Features of Parkinson Disease

Rogan B Tinsley, Chris R Bye, Clare L Parish, Angela Tziotis-Vais, Sonia George, Janetta G Culvenor, Qiao-Xin Li, Colin L Masters, David I Finkelstein, Malcolm K Horne

Journal article  |  2009  |  Annals of Neurology

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

Clare L Parish, Goncalo Castelo-Branco, Nina Rawal, Jan Tonnesen, Andreas Toft Sorensen, Carmen Salto, Merab Kokaia, Olle Lindvall, Ernest Arenas

Journal article  |  2008  |  Journal of Clinical Investigation

Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model

Clare L Parish, Anna Beljajeva, Ernest Arenas, Andras Simon

Journal article  |  2007  |  Development

Inhibition of JNK increases survival of transplanted dopamine neurons in Parkinsonian rats

N Rawal, C Parish, G Castelo-Branco, E Arenas

Journal article  |  2007  |  Cell Death & Differentiation

Stem-cell-based strategies for the treatment of Parkinson's disease

Clare L Parish, Ernest Arenas

Journal article  |  2007  |  Neurodegenerative Diseases

An efficient method for the derivation of mouse embryonic stem cells

Vitezslav Bryja, Sonia Bonilla, Lukas Cajanek, Clare L Parish, Catherine M Schwartz, Yongquan Luo, Mahendra S Rao, Ernest Arenas

Journal article  |  2006  |  STEM CELLS

Mice lacking the alpha 4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and possess impaired dopamine transporter function

CL Parish, J Nunan, DI Finkelstein, FN McNamara, JY Wong, JL Waddington, RM Brown, AJ Lawrence, MK Horne, J Drago

Journal article  |  2005  |  Molecular Pharmacology

Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats

AJ Lawrence, CL Parish, F Chen, DJ Lodge, EV Krstew, K Card, DI Finkelstein, MK Horne

Journal article  |  2005  |  Journal of Neurochemistry

Neurogenesis and functional recovery in Parkinsonian newts

CL Parish, A Beljajeva, E Arenas, A Simon

Conference Proceedings  |  2005  |  MECHANISMS OF DEVELOPMENT

Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's disease

CL Parish, S Parisi, MG Persico, E Arenas, G Minchiotti

Journal article  |  2005  |  Stem Cells

Spontaneous formation of Lewy bodies in a rodent

J Nunan, A Tsiotis-Vais, S George, CL Parish, DK Grandy, DI Finkelstein, J Drago, MK Horne

Conference Proceedings  |  2005  |  BASAL GANGLIA VIII

Quantified assessment of terminal density and innervation.

David I Finkelstein, Davor Stanic, Clare L Parish, John Drago, Malcolm K Horne

Journal article  |  2004  |  Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]

Stereological methods allow for the determination of cell numbers, terminal densities, and, subsequently, the estimation of termin..

Organized development from human embryonic stem cells after injection into immunodeficient mice

K Gertow, S Wolbank, B Rozell, R Sugars, M Andang, CL Parish, MP Imreh, M Wendel, L Ahrlund-Richter

Journal article  |  2004  |  Stem Cells and Development

Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc (vol 86, pg 329, 2003)

D Stanic, CL Parish, WM Zhu, EV Krstew, AJ Lawrence, J Drago, DI Finkelstein, MK Horne

Journal article  |  2003  |  Journal of Neurochemistry

Erratum: Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the Snpc (Journal of Neurochemistry (2003) 86 (329-343)

D Stanic, CL Parish, WM Zhu, EV Krstew, AJ Lawrence, J Drago, DI Finkelstein, MK Horne

Journal article  |  2003  |  Journal of Neurochemistry

Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc

D Stanic, CL Parish, WM Zhu, EV Krstew, AJ Lawrence, J Drago, DI Finkelstein, MK Horne

Journal article  |  2003  |  Journal of Neurochemistry

Macrophages and microglia produce local trophic gradients that stimulate axonal sprouting toward but not beyond the wound edge

PE Batchelor, MJ Porritt, P Martinello, CL Parish, GT Liberatore, GA Donnan, DW Howells

Journal article  |  2002  |  Molecular and Cellular Neuroscience

The role of interleukin-1, interleukin-6, and glia in inducing growth of neuronal terminal arbors in mice

CL Parish, DI Finkelstein, W Tripanichkul, AR Satoskar, J Drago, MK Horne

Journal article  |  2002  |  The Journal of Neuroscience

Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor size

CL Parish, D Stanic, J Drago, E Borrelli, DI Finkelstein, MK Horne

Journal article  |  2002  |  European Journal of Neuroscience

The role of dopamine receptors in regulating the size of axonal arbours

DI Finkelstein, CL Parish, D Stanic, E Borrelli, J Drago, MK Horne

Conference Proceedings  |  2002  |  BASAL GANGLIA VII

The role of dopamine receptors in regulating the size of axonal arbors

CL Parish, DI Finkelstein, J Drago, E Borrelli, MK Horne

Journal article  |  2001  |  The Journal of Neuroscience

Axonal sprouting following lesions of the rat substantia nigra

DI Finkelstein, D Stanic, CL Parish, D Tomas, K Dickson, MK Horne

Journal article  |  2000  |  Neuroscience