Peter Revill

Analysis of Hepatitis B virus haplotype diversity detects striking sequence conservation across genotypes and chronic disease phase.

Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Vithika Suri, Susanna Tan, Becket Feierbach, Anuj Gaggar, Patrick Marcellin, Maria Buti Ferret, Harry LA Janssen, Ed Gane, Henry LY Chan, Danni Colledge, Gillian Rosenberg, Julianne Bayliss, Benjamin P Howden, Stephen A Locarnini, Darren Wong, et al.

Journal article  |  2020  |  Hepatology

BACKGROUND: We conducted haplotype analysis of complete hepatitis B virus (HBV) genomes following deep sequencing from 368 patient..

HBV variants are common in the 'immune-tolerant' phase of chronic hepatitis B

Lilly Yuen, Peter A Revill, Gillian Rosenberg, Josef Wagner, Margaret Littlejohn, Julianne Bayliss, Kathy Jackson, Susanna K Tan, Anuj Gaggar, Kathryn Kitrinos, Mani Subramanian, Ed Gane, Henry LY Chan, Xin Li, Scott Bowden, Stephen Locarnini, Alexander Thompson

Journal article  |  2020  |  Journal of Viral Hepatitis

Nucleos(t)ide analouges (NUC) treatment prevents progression of liver fibrosis in subjects with chronic hepatitis B (CHB). However..

The evolution and clinical impact of hepatitis B virus genome diversity

Peter A Revill, Thomas Tu, Hans J Netter, Lilly KW Yuen, Stephen A Locarnini, Margaret Littlejohn

Journal article  |  2020  |  Nature Reviews Gastroenterology & Hepatology

The global burden of hepatitis B virus (HBV) is enormous, with 257 million persons chronically infected, resulting in more than 88..

Editorial: Strategies and barriers for hepatitis B cure: implications for HIV

Peter A Revill, Sharon R Lewin

Journal article  |  2020  |  Current Opinion in HIV and AIDS

Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference‡.

Markus Cornberg, Anna Suk-Fong Lok, Norah A Terrault, Fabien Zoulim, undefined 2019 EASL-AASLD HBV Treatment Endpoints Conference Faculty

Journal article  |  2020  |  Journal of Hepatology

Representatives from academia, industry, regulatory agencies, and patient groups convened in March 2019 with the primary goal of d..

Analysis of the in vitro replication phenotype of African hepatitis B virus (HBV) genotypes and subgenotypes present in Australia identifies marked differences in DNA and protein expression

E Bannister, V Sozzi, H Mason, S Locarnini, W Hardikar, PA Revill

Journal article  |  2020  |  Virology

Hepatitis B virus infection in Africa is characterised by distinct genotypes with observed differences in natural history and clin..

Analysis of genomic-length HBV sequences to determine genotype and subgenotype reference sequences

Anna L McNaughton, Peter A Revill, Margaret Littlejohn, Philippa C Matthews, M Azim Ansari

Journal article  |  2020  |  Journal of General Virology

Hepatitis B virus (HBV) is a diverse, partially double-stranded DNA virus, with 9 genotypes (A-I), and a putative 10th genotype (J..

A PCR assay to quantify patterns of HBV transcription.

Valentina D'Arienzo, Andrea Magri, James M Harris, Peter AC Wing, Chunkyu Ko, Claudia Orbegozo Rubio, Peter A Revill, Ulrike Protzer, Peter Balfe, Jane A McKeating

Journal article  |  2019  |  Journal of General Virology

Hepatitis B virus (HBV) is the prototype member of the family Hepadnaviridae and replicates via episomal copies of a covalently cl..

Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference.

Markus Cornberg, Anna Suk-Fong Lok, Norah A Terrault, Fabien Zoulim, undefined 2019 EASL-AASLD HBV Treatment Endpoints Conference Faculty

Journal article  |  2019  |  Hepatology

Representatives from academia, industry, regulatory agencies, and patient groups convened in March 2019 with the primary goal of d..

Meeting the Challenge of Eliminating Chronic Hepatitis B Infection

Peter A Revill, Capucine Penicaud, Christian Brechot, Fabien Zoulim

Journal article  |  2019  |  Genes