Peter Revill

Editorial: baseline hepatitis B virus haplotype number may help predict a functional cure in patients with chronic hepatitis B treated with nucleotide analogues-authors' reply.

Josef Wagner, Margaret Littlejohn, Peter A Revill

Journal article  |  2023  |  Aliment Pharmacol Ther

HIV DNA persists in hepatocytes in people with HIV-hepatitis B co-infection on antiretroviral therapy.

Jennifer M Zerbato, Anchalee Avihingsanon, Kasha P Singh, Wei Zhao, Claire Deleage, Elias Rosen, Mackenzie L Cottrell, Ajantha Rhodes, Ashanti Dantanarayana, Carolin Tumpach, Surekha Tennakoon, Megan Crane, David J Price, Sabine Braat, Hugh Mason, Michael Roche, Angela DM Kashuba, Peter A Revill, Jennifer Audsley, Sharon R Lewin

Journal article  |  2023  |  EBioMedicine

BACKGROUND: HIV can infect multiple cells in the liver including hepatocytes, Kupffer cells and infiltrating T cells, but whether ..

Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D HBeAg-positive chronic hepatitis B

Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Ross Martin, Thomas Aeschbacher, Vithika Suri, Susanna K Tan, Becket Feierbach, Anuj Gaggar, Patrick Marcellin, Maria Buti Ferret, Harry LA Janssen, Ed Gane, Niamh Meagher, David J Price, Darren Wong, Alexander T Thompson, Peter A Revill

Journal article  |  2022  |  ALIMENTARY PHARMACOLOGY & THERAPEUTICS

BACKGROUNDS AND AIMS: We investigated associations between hepatitis B virus (HBV) genome-length haplotype number (HN) at baseline..

Exploring the Public Health and Social Implications of Future Curative Hepatitis B Interventions

Jack Wallace, Jacqueline Richmond, Jessica Howell, Behzad Hajarizadeh, Jennifer Power, Carla Treloar, Peter A Revill, Benjamin Cowie, Su Wang, Mark Stoove, Alisa Pedrana, Margaret Hellard

Journal article  |  2022  |  VIRUSES-BASEL

Hepatitis B is a significant global health issue where the 296 million people estimated to live with the infection risk liver dise..

A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook.

Anna Kramvis, Kyong-Mi Chang, Maura Dandri, Patrizia Farci, Dieter Glebe, Jianming Hu, Harry LA Janssen, Daryl TY Lau, Capucine Penicaud, Teresa Pollicino, Barbara Testoni, Florian Van Bömmel, Ourania Andrisani, Maria Beumont-Mauviel, Timothy M Block, Henry LY Chan, Gavin A Cloherty, William E Delaney, Anna Maria Geretti, Adam Gehring, et al.

Journal article  |  2022  |  Nat Rev Gastroenterol Hepatol

Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one million people die annually from HBV..

Hepatitis B Virus Flares After Nucleot(s)ide Analogue Cessation Are Associated With Activation of Toll-Like Receptor Signaling Pathways

Samuel Al Hall, Gareth S Burns, Benjamin J Mooney, Rosemary Millen, Rachel Morris, Sara Vogrin, Vijaya Sundararajan, Dilip Ratnam, Miriam T Levy, John S Lubel, Amanda J Nicoll, Simone Strasser, William Sievert, Paul Desmond, Meng C Ngu, Peter Angus, Marie Sinclair, Christopher Meredith, Gail Matthews, Peter A Revill, et al.

Journal article  |  2022  |  JOURNAL OF INFECTIOUS DISEASES

BACKGROUND: We evaluated the patterns of peripheral Toll-like receptor (TLR) signaling activity and the expression of TLRs and nat..

The in vitro replication phenotype of hepatitis B virus (HBV) splice variant Sp1.

V Sozzi, L McCoullough, H Mason, M Littlejohn, PA Revill

Journal article  |  2022  |  Virology

Although not critical for hepatitis B virus (HBV) replication, splicing of HBV pre-genomic RNA generates multiple HBV splice varia..

Hepatitis B virus splice variants are associated with reduced likelihood of functional cure and differ across phases of chronic hepatitis B infection

Olivia Maslac, Josef Wagner, Vitina Sozzi, Hugh Mason, Evguenia S Svarovskaia, Susanna Tan, Anuj Gaggar, Stephen Locarnini, Lilly Yuen, Margaret Littlejohn, Peter Revill

Journal article  |  2022  |  Journal of Hepatology

Greater sequence diversity during early hepatitis B virus decline on vebicorvir plus entecavir is associated with a lower level of virus rebound following switch to entecavir monotherapy

Lewyn Li, Peter Revill, Ran Yan, Calvin Chan, Hua Tian, Julie Ma, Luisa M Stamm, Man-Fung Yuen, Alexander Thompson, Kathryn M Kitrinos

Journal article  |  2022  |  Journal of Hepatology

Secreted hepatitis B virus splice variants differ by HBV genotype and across phases of chronic hepatitis B infection

Olivia Maslac, Josef Wagner, Vitina Sozzi, Hugh Mason, Jenny Svarovskaia, Susanna Tan, Anuj Gaggar, Stephen Locarnini, Lilly Yuen, Margaret Littlejohn, Peter A Revill

Journal article  |  2022  |  JOURNAL OF VIRAL HEPATITIS

Chronic hepatitis B (CHB) is characterized by progression through different phases of hepatitis B virus (HBV) infection and diseas..