Stuart Berzins

A high-dimensional cytometry atlas of peripheral blood over the human life span

Sedigheh Jalali, Christopher M Harpur, Adam T Piers, Maria Auladell, Louis Perriman, Shuo Li, Kim An, Jeremy Anderson, Stuart P Berzins, Paul Licciardi, Thomas M Ashhurst, Igor E Konstantinov, Daniel G Pellicci

Journal article  |  2022  |  IMMUNOLOGY AND CELL BIOLOGY

Age can profoundly affect susceptibility to a broad range of human diseases. Children are more susceptible to some infectious dise..

Plasma Signaling Factors in Patients With Langerhans Cell Histiocytosis (LCH) Correlate With Relative Frequencies of LCH Cells and T Cells Within Lesions.

Jenée Mitchell, Egle Kvedaraite, Tatiana von Bahr Greenwood, Magda Lourda, Jan-Inge Henter, Stuart P Berzins, George Kannourakis

Journal article  |  2022  |  Front Pediatr

Langerhans cell histiocytosis (LCH) lesions contain an inflammatory infiltrate of immune cells including myeloid-derived LCH cells..

Modulation of TCR signalling components occurs prior to positive selection and lineage commitment in iNKT cells

Xuyen T Dinh, Dragana Stanley, Letitia D Smith, Morgane Moreau, Stuart P Berzins, Adrian Gemiarto, Alan G Baxter, Margaret A Jordan

Journal article  |  2021  |  SCIENTIFIC REPORTS

iNKT cells play a critical role in controlling the strength and character of adaptive and innate immune responses. Their unique fu..

Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes

Maximilien Evrard, Erica Wynne-Jones, Changwei Peng, Yu Kato, Susan N Christo, Raissa Fonseca, Simone L Park, Thomas N Burn, Maleika Osman, Sapna Devi, Jerold Chun, Scott N Mueller, George Kannourakis, Stuart P Berzins, Daniel G Pellicci, William R Heath, Stephen C Jameson, Laura K Mackay

Journal article  |  2021  |  JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-resident memory T (TRM) cells provide long-lasting immune protection. One of the key events controlling TRM cell developmen..

The attributes of plakins in cancer and disease: perspectives on ovarian cancer progression, chemoresistance and recurrence

Tamsin Wesley, Stuart Berzins, George Kannourakis, Nuzhat Ahmed

Journal article  |  2021  |  CELL COMMUNICATION AND SIGNALING

The plakin family of cytoskeletal proteins play an important role in cancer progression yet are under-studied in cancer, especiall..

Thymic development of unconventional T cells: how NKT cells, MAIT cells and gamma delta T cells emerge

Daniel G Pellicci, Hui-Fern Koay, Stuart P Berzins

Journal article  |  2020  |  NATURE REVIEWS IMMUNOLOGY

T cell lineages are defined by specialized functions and differential expression of surface antigens, cytokines and transcription ..

High CD26 and Low CD94 Expression Identifies an IL-23 Responsive V delta 2( ) T Cell Subset with a MAIT Cell-like Transcriptional Profile

Kathleen M Wragg, Hyon-Xhi Tan, Anne B Kristensen, Catriona Nguyen-Robertson, Anthony D Kelleher, Matthew S Parsons, Adam K Wheatley, Stuart P Berzins, Daniel G Pellicci, Stephen J Kent, Jennifer A Juno

Journal article  |  2020  |  CELL REPORTS

Vδ2+ T cells play a critical role in immunity to micro-organisms and cancer but exhibit substantial heterogeneity in humans. Here,..

Foxp3( ) Tregs from Langerhans cell histiocytosis lesions co-express CD56 and have a definitively regulatory capacity

Jenee Mitchell, Jason Kelly, Egle Kvedaraite, Tatiana von Bahr Greenwood, Jan-Inge Henter, Daniel G Pellicci, Stuart P Berzins, George Kannourakis

Journal article  |  2020  |  CLINICAL IMMUNOLOGY

Langerhans cell histiocytosis (LCH) lesions contain myeloid lineage 'LCH' cells. Regulatory T cells (Tregs) are also enriched with..

A Role for MAIT Cells in Colorectal Cancer

Stuart P Berzins, Morgan E Wallace, George Kannourakis, Jason Kelly

Journal article  |  2020  |  FRONTIERS IN IMMUNOLOGY

MAIT cells are MR1-restricted T cells that are well-known for their anti-microbial properties, but they have recently been associa..

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

Hui Fern Koay, Shian Su, Daniela Amann-Zalcenstein, Stephen R Daley, Iain Comerford, Carly E Whyte, Igor E Konstantinov, Yves d'Udekem, Tracey Baldwin, Peter F Hickey, Stuart P Berzins, Jeffrey YW Mak, Axel Kallies, Zhenjun Chen, Simone Nussing, Katherine Kedzierska, Laura K Mackay, Shaun R McColl, Elissa K Deenick, David P Fairlie, et al.

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY