Michael Reade

Delayed tracheoesophageal fistula and refractory respiratory failure caused by inhalation burns and emergency venovenous ECMO to facilitate its management: a case report.

Jayesh Dhanani, Jason Pincus, Shane Townsend, George Pang, Elizabeth Vujcich, Morgan Windsor, Michael C Reade

Journal article  |  2023  |  J Burn Care Res

Acquired tracheoesophageal fistulae are uncommon in burn patients but can occur as a complication of inhalation injury. We report ..

Whose side are you on? Complexities arising from the non-combatant status of military medical personnel.

Michael C Reade

Journal article  |  2023  |  Monash Bioeth Rev

Since the mid-1800s, clergy, doctors, other clinicians, and military personnel who specifically facilitate their work have been de..

Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU study.

Chiara Robba, Francesca Graziano, Angelo Guglielmi, Paola Rebora, Stefania Galimberti, Fabio S Taccone, Giuseppe Citerio, undefined SYNAPSE-ICU Investigators

Journal article  |  2023  |  Intensive Care Med

PURPOSE: Uncertainties remain about the safety and efficacy of therapies for managing intracranial hypertension in acute brain inj..

Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level.

Michael C Reade

Journal article  |  2022  |  Crit Care

BACKGROUND: The Haemorrhage, Airway, Breathing, Circulation, Disability, Exposure/Environmental control approach to individual pat..

Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials)

Michael C Reade, Denese C Marks, Belinda Howe, Shay McGuinness, Rachael Parke, Leanlove Navarra, Richard Charlewood, Lacey Johnson, Zoe McQuilten

Journal article  |  2022  |  BMJ OPEN

INTRODUCTION: Cryopreservation at -80°C in dimethylsulphoxide extends platelet shelf-life from 7 days to 2 years. Only limited com..

Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.

John PR Moore, Yahya Shehabi, Michael C Reade, Michael Bailey, John F Fraser, Lauren Murray, Christopher Anstey, Mervyn Singer

Journal article  |  2022  |  Crit Care

BACKGROUND: Sedative agents may variably impact the stress response. Dexmedetomidine is a sympatholytic alpha2-adrenergic agonist ..

Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III).

Yahya Shehabi, Ary Serpa Neto, Rinaldo Bellomo, Belinda D Howe, Yaseen M Arabi, Michael Bailey, Frances E Bass, Suhaini Bin Kadiman, Colin J McArthur, Michael C Reade, Ian M Seppelt, Jukka Takala, Matt P Wise, Steve A Webb, undefined SPICE III study investigators

Journal article  |  2022  |  Am J Respir Crit Care Med

RATIONALE: Sedation Practice in Intensive Care Evaluation (SPICE-III) trial reported significant heterogeneity in mortality with d..

Level of sedation in critically ill adult patients: a protocol for a systematic review with meta-analysis and trial sequential analysis.

Ameldina Ceric, Johan Holgersson, Teresa May, Markus B Skrifvars, Johanna Hästbacka, Manoj Saxena, Anders Aneman, Anthony Delaney, Michael C Reade, Candice Delcourt, Janus Jakobsen, Niklas Nielsen

Journal article  |  2022  |  BMJ Open

INTRODUCTION: It is standard of care to provide sedation to critically ill patients to reduce anxiety, discomfort and promote tole..

Fingolimod does not prevent syndecan-4 shedding from the endothelial glycocalyx in a cultured human umbilical vein endothelial cell model of vascular injury.

Elissa M Milford, Lara Meital, Anna Kuballa, Michael C Reade, Fraser D Russell

Journal article  |  2022  |  Intensive Care Med Exp

BACKGROUND: Shedding of the endothelial glycocalyx (EG) is associated with poor outcomes in a range of conditions including sepsis..

A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit

J Wiebe, J Lipman, MC Reade

Journal article  |  2022  |  Critical Care and Resuscitation

Medications prescribed for indications or at doses, frequencies or durations not approved by the Australian Therapeutic Goods Admi..