Michaela Petter

Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences

Jingyi Tang, Scott A Chisholm, Lee M Yeoh, Paul R Gilson, Anthony T Papenfuss, Karen P Day, Michaela Petter, Michael F Duffy

Journal article  |  2020  |  EPIGENETICS & CHROMATIN

BACKGROUND: The malaria parasite Plasmodium falciparum has an unusually euchromatic genome with poorly conserved positioning of nu..

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

Anna Bachmann, Ellen Bruske, Ralf Krumkamp, Louise Turners, J Stephan Wichers, Michaels Petter, Jana Held, Michael F Duffy, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Bertrand Lell, Thomas Laystsen, Matthias Frank, Benjamin Mordmueller, Egbert Tannich

Journal article  |  2019  |  PLOS PATHOGENS

The pathogenesis of Plasmodium falciparum malaria is linked to the variant surface antigen PfEMP1, which mediates tethering of inf..

ApiAP2 Transcription Factors in Apicomplexan Parasites

Myriam D Jeninga, Jennifer E Quinn, Michaela Petter

Journal article  |  2019  |  PATHOGENS

Apicomplexan parasites are protozoan organisms that are characterised by complex life cycles and they include medically important ..

Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and mechanisms for liver-stage differentiation in relapsing malaria.

Aaron Jex, Ivo Mueller, Stefan Kappe, Sebastian Mikolajczak, Jetsumon Sattabongkot, Rapatbhorn Patrapuvich, Scott Lindner, Erika Flannery, Cristian Koepfli, Brendan Ansell, Anita Lerch, Samantha Emery, Sarah Charnaud, Jeffrey Smith, Nicholas Merrienne, Kristian Swearingen, Robert Moritz, Michaela Petter, M Duffy, Veruda Chuenchob

Journal article  |  2019  |  International Journal for Parasitology

Plasmodium vivax is the key obstacle to malaria elimination in Asia and Latin America, largely attributed to its ability to form r..

Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and potential mechanisms for liver-stage differentiation

undefined Vivax Sporozoite Consortium, Ivo Muller, Aaron Jex, Stefan I. Kappe, Sebastian Mikolajczak, Jetsumon Sattabongkot, Rapatbhorn Patrapuvich, Scott Lindner, Erika Flannery, Cristian Koepfli, Brendan Ansell, Anita Lerch, Samantha Emery-Corbin, Sarah Charnaud, Jeffrey Smith, Nicolas Merrienne, Kristian Swearingen, Robert Moritz, Michaela Petter, Michael Duffy, et al.

Journal article  |  2017

ABSTRACT Plasmodium vivax is the key obstacle to malaria elimination in Asia and Latin America, largely attributed to its ability ..

Activation and clustering of a Plasmodium falciparum var gene are affected by subtelomeric sequences

Michael F Duffy, Jingyi Tang, Fransisca Sumardy, Hanh HT Nguyen, Shamista A Selvarajah, Gabrielle A Josling, Karen P Day, Michaela Petter, Graham V Brown

Journal article  |  2017  |  FEBS JOURNAL

The Plasmodium falciparum var multigene family encodes the cytoadhesive, variant antigen PfEMP1. P. falciparum antigenic variation..

A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies

Jo-Anne Chan, Katherine B Howell, Christine Langer, Alexander G Maier, Wina Hasang, Stephen J Rogerson, Michaela Petter, Joanne Chesson, Danielle I Stanisic, Michael F Duffy, Brian M Cooke, Peter M Siba, Ivo Mueller, Peter C Bull, Kevin Marsh, Freya JI Fowkes, James G Beeson

Journal article  |  2016  |  CELLULAR AND MOLECULAR LIFE SCIENCES

Antibodies to blood-stage antigens of Plasmodium falciparum play a pivotal role in human immunity to malaria. During parasite deve..

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

Anna Bachmann, Michaela Petter, Ralf Krumkamp, Meral Esen, Jana Held, Judith AM Scholz, Tao Li, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmueller, Michael F Duffy, Egbert Tannich

Journal article  |  2016  |  PLOS PATHOGENS

Virulence of the most deadly malaria parasite Plasmodium falciparum is linked to the variant surface antigen PfEMP1, which is enco..

A comparative study of the localization and membrane topology of members of the RIFIN, STEVOR and PfMC-2TM protein families in Plasmodium falciparum-infected erythrocytes

Anna Bachmann, Judith Anna Marie Scholz, Marthe Janssen, Mo-Quen Klinkert, Egbert Tannich, Iris Bruchhaus, Michaela Petter

Journal article  |  2015  |  MALARIA JOURNAL

BACKGROUND: Variant surface antigens (VSA) exposed on the membrane of Plasmodium falciparum infected erythrocytes mediate immune e..

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

Gabrielle A Josling, Michaela Petter, Sophie C Oehring, Archna P Gupta, Olivier Dietz, Danny W Wilson, Thomas Schubert, Gernot Laengst, Paul R Gilson, Brendan S Crabb, Suzette Moes, Paul Jenoe, Shu Wei Lim, Graham V Brown, Zbynek Bozdech, Till S Voss, Michael F Duffy

Journal article  |  2015  |  CELL HOST & MICROBE

During red-blood-cell-stage infection of Plasmodium falciparum, the parasite undergoes repeated rounds of replication, egress, and..