Gayle Davey obtained her PhD from Monash University followed by a post-doctoral position at the University of Minnesota, USA investigating the development of CD8 T cells in the thymus. Now as a Senior Research Officer in the Heath laboratory, current projects are focussed around peripheral T cell function.
Gayle joined the University of Melbourne in 2008.
Find out more about Gayle Davey's experience
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Gayle Davey's selected work
CD8( ) T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T..
IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blo..
Development of a Novel CD4( ) TCR Transgenic Line That Reveals a Dominant Role for CD8( ) ..
T cell help amplifies innate signals in CD8 DC for optimal CD8 T cell priming
Displaying the most recent project by Gayle Davey.
Displaying the 55 most recent scholarly works by Gayle Davey.
CD8( ) T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver
Lauren E Holz, Julia E Prier, David Freestone, Thiago M Steiner, Kieran English, Darryl N Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M Davey, Dale Godfrey, Katsuyuki Yui, Laura K Mackay, Mireille H Lahoud, Irina Caminschi, Geoffrey McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R Heath
Journal article | 2018 | Cell Reports
IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blood-Stage Plasmodium Infection
Kylie R James, Megan SF Soon, Ismail Sebina, Daniel Fernandez-Ruiz, Gayle Davey, Urijah N Liligeto, Arya Sheela Nair, Lily G Fogg, Chelsea L Edwards, Shannon E Best, Lianne IM Lansink, Kate Schroder, Jane AC Wilson, Rebecca Austin, Andreas Suhrbier, Steven W Lane, Geoffrey R Hill, Christian R Engwerda, William R Heath, Ashraful Haque
Journal article | 2018 | The Journal of Immunology
Development of a Novel CD4( ) TCR Transgenic Line That Reveals a Dominant Role for CD8( ) Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria
Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari, Claerwen M Jones, Wei Yi Ng, Gayle M Davey, Dorothee Berthold, Lauren Holz, Yu Kato, Matthias H Enders, Ganchimeg Bayarsaikhan, Sanne H Hendriks, Lianne IM Lansink, Jessica A Engel, Megan SF Soon, Kylie R James, Anton Cozijnsen, Vanessa Mollard, Alessandro D Uboldi, Christopher J Tonkin, et al.
Journal article | 2017 | The Journal of Immunology
Liver-Resident Memory CD8( ) T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection
Daniel Fernandez-Ruiz, Wei Yi Ng, Lauren E Holz, Joel Z Ma, Ali Zaid, Yik Chun Wong, Lei Shong Lau, Vanessa Mollard, Anton Cozijnsen, Nicholas Collins, Jessica Li, Gayle M Davey, Yu Kato, Sapna Devi, Roghieh Skandari, Michael Pauley, Jonathan H Manton, Dale I Godfrey, Asolina Braun, Szun Szun Tay, et al.
Journal article | 2016 | Immunity
Using a "prime-and-trap" vaccine strategy to generate liver TRM and protect mice form malaria liver-stage infection
WY Ng, D Fernandez-Ruiz, J Ma, A Zaid, YC Wong, LS Lau, V Mollard, A Cozijnsen, N Collins, J Li, GM Davey, L Holz, SS Tay, PS Tan, DG Bowen, F Koch-Nolte, R Bjoern, FR Carbone, BS Crabb, M Lahoud, et al.
Conference Proceedings | 2016 | EUROPEAN JOURNAL OF IMMUNOLOGY
T Cell Help Amplifies Innate Signals in CD8( ) DCs for Optimal CD8( ) T Cell Priming
Marie Greyer, Paul G Whitney, Angus T Stock, Gayle M Davey, Christina Tebartz, Annabell Bachem, Justine D Mintern, Richard A Strugnell, Stephen J Turner, Thomas Gebhardt, Meredith O'Keeffe, William R Heath, Sammy Bedoui
Journal article | 2016 | Cell Reports
Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall
Yu Kato, Ali Zaid, Gayle M Davey, Scott N Mueller, Stephen L Nutt, Dimitra Zotos, David M Tarlinton, Ken Shortman, Mireille H Lahoud, William R Heath, Irina Caminschi
Journal article | 2015 | The Journal of Immunology
CD8( ) T Cells from a Novel T Cell Receptor Transgenic Mouse Induce Liver-Stage Immunity That Can Be Boosted by Blood-Stage Infection in Rodent Malaria
Lei Shong Lau, Daniel Fernandez-Ruiz, Vanessa Mollard, Angelika Sturm, Michelle A Neller, Anton Cozijnsen, Julia L Gregory, Gayle M Davey, Claerwen M Jones, Yi-Hsuan Lin, Ashraful Haque, Christian R Engwerda, Catherine Q Nie, Diana S Hansen, Kenneth M Murphy, Anthony T Papenfuss, John J Miles, Scott R Burrows, Tania de Koning-Ward, Geoffrey I McFadden, et al.
Journal article | 2014 | PLoS Pathogens
Breakdown in Repression of IFN-gamma mRNA Leads to Accumulation of Self-Reactive Effector CD8( ) T Cells
Pheh-Ping Chang, Sau K Lee, Xin Hu, Gayle Davey, Guowen Duan, Jae-Ho Cho, Guna Karupiah, Jonathan Sprent, William R Heath, Edward M Bertram, Carola G Vinuesa
Journal article | 2012 | Journal of Immunology
Proteomic and Metabolomic Analyses of Mitochondrial Complex I-deficient Mouse Model Generated by Spontaneous B2 Short Interspersed Nuclear Element (SINE) Insertion into NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4 (Ndufs4) Gene
Dillon W Leong, Jasper C Komen, Chelsee A Hewitt, Estelle Arnaud, Matthew McKenzie, Belinda Phipson, Melanie Bahlo, Adrienne Laskowski, Sarah A Kinkel, Gayle M Davey, William R Heath, Anne K Voss, Rene P Zahedi, James J Pitt, Roman Chrast, Albert Sickmann, Michael T Ryan, Gordon K Smyth, David R Thorburn, Hamish S Scott
Journal article | 2012 | Journal of Biological Chemistry
Blood-Stage Plasmodium berghei Infection Generates a Potent, Specific CD8( ) T-Cell Response Despite Residence Largely in Cells Lacking MHC I Processing Machinery
Lei Shong Lau, Daniel Fernandez Ruiz, Gayle M Davey, Tania F de Koning-Ward, Anthony T Papenfuss, Francis R Carbone, Andrew G Brooks, Brendan S Crabb, William R Heath
Journal article | 2011 | Journal of Infectious Diseases
Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance
Francois-Xavier Hubert, Sarah A Kinkel, Gayle M Davey, Belinda Phipson, Scott N Mueller, Adrian Liston, Anna I Proietto, Ping ZF Cannon, Simon Forehan, Gordon K Smyth, Li Wu, Christopher C Goodnow, Francis R Carbone, Hamish S Scott, William R Heath
Journal article | 2011 | Blood
Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype
Mireille H Lahoud, Fatma Ahmet, Susie Kitsoulis, Soo San Wan, David Vremec, Chin-Nien Lee, Belinda Phipson, Wei Shi, Gordon K Smyth, Andrew M Lew, Yu Kato, Scott N Mueller, Gayle M Davey, William R Heath, Ken Shortman, Irina Caminschi
Journal article | 2011 | Journal of Immunology
Murine CD8 alpha DCs and human BDCA3 DCs produce large amounts of IFN-lambda in response to poly IC and DNA viruses
Henning Lauterbach, Barbara Bathke, Stefanie Gilles, Claudia Traidl-Hoffmann, Christian Luber, Gyoergy Fejer, Marina Freudenberg, Gayle Davey, David Vremec, Axel Kallies, Li Wu, Ken Shortman, Paul Chaplin, Mark Suter, Meredith O'Keeffe, Hubertus Hochrein
Journal article | 2011 | JOURNAL OF IMMUNOLOGY
Mouse CD8 alpha( ) DCs and human BDCA3( ) DCs are major producers of IFN-lambda in response to poly IC
Henning Lauterbach, Barbara Bathke, Stefanie Gilles, Claudia Traidl-Hoffmann, Christian A Luber, Gyoergy Fejer, Marina A Freudenberg, Gayle M Davey, David Vremec, Axel Kallies, Li Wu, Ken Shortman, Paul Chaplin, Mark Suter, Meredith O'Keeffe, Hubertus Hochrein
Journal article | 2010 | Journal of Experimental Medicine
Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance
Ian A Parish, Jason Waithman, Gayle M Davey, Gabrielle T Belz, Justine D Mintern, Christian Kurts, Robyn M Sutherland, Francis R Carbone, William R Heath
Journal article | 2009 | Proceedings of the National Academy of Sciences of the United States of America
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement
Irina Caminschi, Anna I Proietto, Fatma Ahmet, Susie Kitsoulis, Joo Shin Teh, Jennifer CY Lo, Alexandra Rizzitelli, Li Wu, David Vremec, Serani LH van Dommelen, Ian K Campbell, Eugene Maraskovsky, Hal Braley, Gayle M Davey, Patricia Mottram, Nicholas van De Velde, Kent Jensen, Andrew M Lew, Mark D Wright, William R Heath, et al.
Journal article | 2008 | Blood
Blood-stage Plasmodium infection induces CD8( ) T lymphocytes to parasite-expressed antigens, largely regulated by CD8 alpha( ) dendritic cells
Rachel J Lundie, Tania F de Koning-Ward, Gayle M Davey, Catherine Q Nie, Diana S Hansen, Lei Shong Lau, Justine D Mintern, Gabrielle T Belz, Louis Schofield, Francis R Carbone, Jose A Villadangos, Brendan S Crabb, William R Heath
Journal article | 2008 | Proceedings of the National Academy of Sciences of the United States of America
Induction of antigen-specific T cell responses following blood-stage Plasmodium infection occurs mainly via CD8 alpha dendritic cells but is short-lived.
Rachel J Lundie, Tania F de Koning-Ward, Gayle M Davey, Catherine Q Nie, Diana S Hansen, Louis Schofield, Gabrielle T Belz, Francis R Carbone, Jose A Villadangos, Brendan S Crabb, William R Heath
Conference Proceedings | 2008 | INTERNATIONAL JOURNAL FOR PARASITOLOGY
Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells
Irina Caminschi, Fatma Ahmet, Klaus Heger, Jason Brady, Stephen L Nutt, David Vremec, Suzanne Pietersz, Mireille H Lahoud, Louis Schofi Eld, Diana S Hansen, Meredith O'Keeffe, Mark J Smyth, Sammy Bedoui, Gayle M Davey, Jose A Villadangos, William R Heath, Ken Shortman
Journal article | 2007 | Journal of Experimental Medicine
The dominant role of CD8( ) dendritic cells in cross-presentation is not dictated by antigen capture
Petra Schnorrer, Georg MN Behrens, Nicholas S Wilson, Joanne L Pooley, Christopher M Smith, Dima EI-Sukkari, Gayle Davey, Fiona Kupresanin, Ming Li, Eugene Maraskovsky, Gabrielle T Belz, Francis R Carbone, Ken Shortman, William R Heath, Jose A Villadangos
Journal article | 2006 | Proceedings of the National Academy of Sciences of the United States of America
Loss of Bim increases T cell production and function in interleukin 7 receptor-deficient mice
M Pellegrini, P Bouillet, M Robati, GT Belz, GM Davey, A Strasser
Journal article | 2004 | Journal of Experimental Medicine
Interleukin (IL)-7 receptor (R) signaling is essential for T and B lymphopoiesis by promoting proliferation, differentiation, and ..
Thymic shared antigen-2: a novel cell surface marker associated with T cell differentiation and activation.
SP Berzins, GM Davey, ES Randle-Barrett, MA Malin, BJ Classon, S Fraser, RL Boyd
Journal article | 1999 | Journal of Immunology
Thymic shared Ag-2 (TSA-2) is a 28-kDa, glycophosphatidylinitosol-linked cell surface molecule expressed on various T cell and thy..
Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells
GM Davey, SL Schober, BT Endrizzi, AK Dutcher, SC Jameson, KA Hogquist
Journal article | 1998 | The Journal of Experimental Medicine
During T cell development, thymocytes which are tolerant to self-peptides but reactive to foreign peptides are selected. The curre..
Characterization of the AKR thymic microenvironment and its influence on thymocyte differentiation and lymphoma development.
GM Davey, CL Tucek-Szabo, RL Boyd
Journal article | 1996 | Leukemia Research
The thymic stroma has long been implicated in AKR thymic leukaemia. In this study an extensive panel of monoclonal antibodies was ..
Senior Research Officer
Microbiology And Immunology
Australian Society for Medical Research
Australasian Society for Immunology Inc
DOCTORATE OF PHILOSOPHY
BACHELOR OF SCIENCE (HONS)