Andrew Allen

Use of a physiological reflex to standardize vagal nerve stimulation intensity improves data reproducibility in a memory extinction assay

Andrew G Butler, Erin L O'Callaghan, Allen M Allen, Stuart J McDougall

Journal article  |  2021  |  BRAIN STIMULATION

BACKGROUND: Modulating brainstem activity, via electrical vagus nerve stimulation (VNS), influences cognitive functions, including..

Selective optogenetic stimulation of efferent fi bers in the vagus nerve of a large mammal

Lindsea C Booth, Song T Yao, Alla Korsak, David GS Farmer, Sally G Hood, Daniel McCormick, Quinn Boesley, Angela A Connelly, Stuart J McDougall, Willian S Korim, Sarah-Jane Guild, Svetlana Mastitskaya, Phuong Le, Anja G Teschemacher, Sergey Kasparov, Gareth L Ackland, Simon C Malpas, Robin M McAllen, Andrew M Allen, Clive N May, et al.

Journal article  |  2021  |  BRAIN STIMULATION

BACKGROUND: Electrical stimulation applied to individual organs, peripheral nerves, or specific brain regions has been used to tre..

A Chemogenetic Tool that Enables Functional Neural Circuit Analysis

Hoai Buu Ngo, Mariana R Melo, Sharon Layfield, Angela A Connelly, Jaspreet K Bassi, Lin Xie, Clement Menuet, Stuart J McDougall, Ross AD Bathgate, Andrew M Allen

Journal article  |  2020  |  CELL REPORTS

Chemogenetics enables manipulation of neuronal activity in experimental animals. While providing information about the transduced ..

PreBotzinger complex neurons drive respiratory modulation of blood pressure and heart rate

Clement Menuet, Angela A Connelly, Jaspreet K Bassi, Mariana R Melo, Sheng Le, Jessica Kamar, Natasha N Kumar, Stuart J McDougall, Simon McMullan, Andrew M Allen

Journal article  |  2020  |  ELIFE

Heart rate and blood pressure oscillate in phase with respiratory activity. A component of these oscillations is generated central..

Does glyceryl trinitrate cause central sympatholytic effects? Insights from a case of baroreflex failure

Sarah Tan, Lin Xie, Robert Anderson, Andrew Hammond, Angelina Y Fong, Seok Lim, Andrew M Allen, Stephen B Harrap

Journal article  |  2020  |  INTERNAL MEDICINE JOURNAL

Whether part of the blood pressure lowering effects of glyceryl trinitrate (GTN) is the result of centrally mediated reduction in ..

Extensive Inhibitory Gating of Viscerosensory Signals by a Sparse Network of Somatostatin Neurons

Kimberly R Thek, Sarah JM Ong, David C Carter, Jaspreet K Bassi, Andrew M Allen, Stuart J McDougall

Journal article  |  2019  |  JOURNAL OF NEUROSCIENCE

Integration and modulation of primary afferent sensory information begins at the first terminating sites within the CNS, where cen..

Intrathecal Administration of Losartan Reduces Directly Recorded Cardiac Sympathetic Nerve Activity in Ovine Heart Failure

Simon Leversha, Andrew M Allen, Clive N May, Rohit Ramchandra

Journal article  |  2019  |  HYPERTENSION

Early and preferential activation of cardiac sympathetic nerve activity (CSNA) is one of the strongest prognostic markers of heart..

Neurohumoral interactions contributing to renal vasoconstriction and decreased renal blood flow in heart failure

Rohit Ramchandra, Daniel T Xing, Marcus Matear, Gavin Lambert, Andrew M Allen, G Clive N May

Journal article  |  2019  |  AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

In heart failure (HF), increases in renal sympathetic nerve activity (RSNA), renal norepinephrine spillover, and renin release cau..

Involvement of Phox2B Neurons Located in the Commissural NTs with the Maintenance of Hypertension in SH Rats

Mariana Del Rosso de Melo, Sarah JM Ong, Angela A Connelly, Jaspreet K Bassi, Eduardo Colombari, Andrew M Allen

Journal article  |  2019  |  The FASEB Journal

Respiratory sympathetic modulation is augmented in chronic kidney disease

Manash Saha, Clement Menuet, Qi-Jian Sun, Peter GR Burke, Cara M Hildreth, Andrew M Allen, Jacqueline K Phillips

Journal article  |  2019  |  RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Respiratory modulation of sympathetic nerve activity (respSNA) was studied in a hypertensive rodent model of chronic kidney diseas..