Brent McKenzie

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Ian K Campbell, David Leong, Kirsten M Edwards, Veronika Rayzman, Milica Ng, Gabrielle L Goldberg, Nicholas J Wilson, Karen Scalzo-Inguanti, Charley Mackenzie-Kludas, Kate E Lawlor, Ian P Wicks, Lorena E Brown, Adriana Baz Morelli, Con Panousis, Michael J Wilson, Andrew D Nash, Brent S McKenzie, Arna E Andrews

Journal article  |  2016  |  The Journal of Immunology

GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

Angus T Stock, Jacinta A Hansen, Matthew A Sleeman, Brent S McKenzie, Ian P Wicks

Journal article  |  2016  |  Journal of Experimental Medicine

G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis (vol 186, pg 172, 2016)

Gabrielle L Goldberg, Ann L Cornish, Jane Murphy, Ee Shan Pang, Damian B D'Silva, Lyndell L Lim, Ian K Campbell, Karen Scalzo-Inguanti, Xiangting Chen, Paul G McMenamin, Eugene Maraskovsky, Brent S McKenzie, Ian P Wicks

Journal article  |  2016  |  American Journal Of Pathology

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

Claire Pearson, Emily E Thornton, Brent McKenzie, Anna-Lena Schaupp, Nicky Huskens, Thibault Griseri, Nathaniel West, Sim Tung, Benedict P Seddon, Holm H Uhlig, Fiona Powrie

Journal article  |  2016  |  eLife

G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis

Gabrielle L Goldberg, Ann L Cornish, Jane Murphy, Ee Shan Pang, Lyndell L Lim, Ian K Campbell, Karen Scalzo-Inguanti, Xiangting Chen, Paul G McMenamin, Eugene Maraskovsky, Brent S McKenzie, Ian P Wicks

Journal article  |  2016  |  The American Journal of Pathology

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis

Thibault Griseri, Isabelle C Arnold, Claire Pearson, Thomas Krausgruber, Chris Schiering, Fanny Franchini, Julie Schulthess, Brent S McKenzie, Paul R Crocker, Fiona Powrie

Journal article  |  2015  |  IMMUNITY

Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils

Ian K Campbell, Sylvia Miescher, Donald R Branch, Patrick J Mott, Alan H Lazarus, Dongji Han, Eugene Maraskovsky, Adrian W Zuercher, Anton Neschadim, Danila Leontyev, Brent S McKenzie, Fabian Kaesermann

Journal article  |  2014  |  Journal of Immunology

Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation

Thibault Griseri, Brent S McKenzie, Chris Schiering, Fiona Powrie

Journal article  |  2012  |  Immunity

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

Robert JJ O'Donoghue, Darryl A Knight, Carl D Richards, Cecilia M Prele, Hui Ling Lau, Andrew G Jarnicki, Jessica Jones, Steven Bozinovski, Ross Vlahos, Stefan Thiem, Brent S McKenzie, Bo Wang, Philip Stumbles, Geoffrey J Laurent, Robin J McAnulty, Stefan Rose-John, Hong Jian Zhu, Gary P Anderson, Matthias R Ernst, Steven E Mutsaers

Journal article  |  2012  |  EMBO Molecular Medicine

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease.

Corinne Cayatte, Barbara Joyce-Shaikh, Felix Vega, Katia Boniface, Jeffrey Grein, Erin Murphy, Wendy M Blumenschein, Smiley Chen, Maria-Christina Malinao, Beth Basham, Robert H Pierce, Edward P Bowman, Brent S McKenzie, Charles O Elson, William A Faubion, Rene de Waal Malefyt, Robert A Kastelein, Daniel Cua, Terrill K McClanahan, Maribel Beaumont

Journal article  |  2012  |  Clinical and Translational Gastroenterology

OBJECTIVES: Interleukin-23 (IL-23) has emerged as a new therapeutic target for the treatment of inflammatory bowel disease (IBD). ..