Harry Georgiou

Late/post-term decidual basalis-derived mesenchymal stem/stromal cells show evidence of advanced ageing and downregulation of microRNA-516b-5p

Ramin Khanabdali, Shixuan Zheng, Phillip E Melton, Harry M Georgiou, Eric Moses, Shaun P Brennecke, Bill Kalionis

Journal article  |  2021  |  PLACENTA

INTRODUCTION: The placenta is a short-lived organ, yet it shows signs of progressive ageing in the third trimester. Studies of age..

Postpartum circulating microRNA enhances prediction of future type 2 diabetes in women with previous gestational diabetes

Mugdha V Joglekar, Wilson KM Wong, Fahmida K Ema, Harry M Georgiou, Alexis Shub, Anandwardhan A Hardikar, Martha Lappas

Journal article  |  2021  |  DIABETOLOGIA

AIMS/HYPOTHESIS: Type 2 diabetes mellitus is a major cause of morbidity and death worldwide. Women with gestational diabetes melli..

Ageing in human parturition: impetus of the gestation clock in the decidua

Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Bill Kalionis

Journal article  |  2020  |  BIOLOGY OF REPRODUCTION

Despite sharing many common features, the relationship between ageing and parturition remains poorly understood. The decidua is a ..

Decidual mesenchymal stem/stromal cell-derived extracellular vesicles ameliorate endothelial cell proliferation, inflammation, and oxidative stress in a cell culture model of preeclampsia

Shixuan Zheng, Aiwu Shi, Sophia Hill, Claire Grant, Maria I Kokkinos, Padma Murthi, Harry M Georgiou, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Pregnancy Hypertension

Oxidative stress and endothelial dysfunction contribute substantially to the pathogenesis of preeclampsia (PE). Decidual mesenchym..

Functional changes in decidual mesenchymal stem/stromal cells are associated with spontaneous onset of labour

Joan C Wijaya, Ramin Khanabdali, Harry M Georgiou, Maria Kokkinos, Patrick F James, Shaun P Brennecke, Bill Kalionis

Journal article  |  2020  |  Molecular Human Reproduction

Ageing and parturition share common pathways, but their relationship remains poorly understood. Decidual cells undergo ageing as p..

Preterm birth prediction in asymptomatic women at mid-gestation using a panel of novel protein biomarkers: the Prediction of PreTerm Labor (PPeTaL) study.

San Min Leow, Megan KW Di Quinzio, Zhen Long Ng, Claire Grant, Tal Amitay, Ying Wei, Moshe Hod, Penelope M Sheehan, Shaun P Brennecke, Nir Arbel, Harry M Georgiou

Journal article  |  2020  |  American Journal of Obstetrics and Gynecology MFM

BACKGROUND: Accurate prediction of spontaneous preterm labor/preterm birth in asymptomatic women remains an elusive clinical chall..

The effect of breastfeeding on postpartum glucose tolerance and lipid profiles in women with gestational diabetes mellitus

Alexis Shub, Manisha Miranda, Harry M Georgiou, Elizabeth A McCarthy, Martha Lappas

Journal article  |  2019  |  International Breastfeeding Journal

Background: We aimed to investigate the association of breastfeeding on postpartum glucose levels and lipid profiles in women diag..

A Novel Panel of Mid-trimester Biomarkers to Predict Preterm Labour

M Di Quinzio, S Brennecke, P Sheehan, C Grant, N Arbel, S Leow, Z Ng, T Amitay, Y Wei, H Georgiou

Conference Proceedings  |  2019  |  AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY

Do Postpartum Levels of Apolipoproteins Prospectively Predict the Development of Type 2 Diabetes in Women with Previous Gestational Diabetes Mellitus?

Martha Lappas, Harry M Georgiou, Anida Velagic, Jane C Willcox, Michael Permezel, Alexis Shub

Journal article  |  2019  |  EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

AIMS: The risk of developing type 2 diabetes is greater in women with previous gestational diabetes mellitus (GDM). Apolipoprotein..

Postpartum maternal adipokines and infant weight for length at 1 year in women with gestational diabetes

Alexis Shub, Leonid Churilov, Manisha Miranda, Harry M Georgiou, Martha Lappas

Journal article  |  2019  |  JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE

BACKGROUND: Maternal, cord blood and childhood adipokines have been associated with childhood obesity. We investigated whether pos..