Adrienne Sexton

Young-onset dementia: A systematic review of the psychological and social impact on relatives.

Maddison Wiggins, Alison McEwen, Adrienne Sexton

Journal article  |  2023  |  Patient Educ Couns

OBJECTIVE: Young-onset dementia (YOD) has significant impact for the affected person, but also has far-reaching effects on the fam..

Psychiatric genetic counseling: A survey of Australian genetic counselors' practice and attitudes

Joanne Isbister, Adrienne Sexton, Laura E Forrest, Paul James, James Dowty, Jessica Taylor, Jehannine Austin, Ingrid Winship

Journal article  |  2022  |  JOURNAL OF GENETIC COUNSELING

Genetic counseling plays a critical role in supporting individuals and their families' adaption to psychiatric conditions, address..

Clinical impact of whole-genome sequencing in patients with early-onset dementia

Aamira J Huq, Bryony Thompson, Mark F Bennett, Adam Bournazos, Shobhana Bommireddipalli, Alexandra Gorelik, Joshua Schultz, Adrienne Sexton, Rebecca Purvis, Kirsty West, Megan Cotter, Giulia Valente, Andrew Hughes, Moeen Riaz, Maie Walsh, Sarah Farrand, Samantha M Loi, Trevor Kilpatrick, Amy Brodtmann, David Darby, et al.

Journal article  |  2022  |  JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

BACKGROUND: In the clinical setting, identification of the genetic cause in patients with early-onset dementia (EOD) is challengin..

Real world outcomes and implementation pathways of exome sequencing in an adult genetic department.

Maie Walsh, Kirsty West, Jessica A Taylor, Bryony A Thompson, Adelaide Hopkins, Adrienne Sexton, Abiramy Ragunathan, Kunal P Verma, Julie Panetta, Ebony Matotek, Michael C Fahey, Michael Christie, Ingrid M Winship, Alison H Trainer, Paul A James

Journal article  |  2022  |  Genet Med

PURPOSE: This study aimed to correlate the indications and diagnostic yield of exome sequencing (ES) in adult patients across vari..

Assessing the acceptability, feasibility, and usefulness of a psychosocial screening tool to patients and clinicians in a clinical genetics service in Australia

Katrina Monohan, Rebecca Purvis, Adrienne Sexton, Maira Kentwell, Monica Thet, Lesley Stafford, Laura Forrest

Journal article  |  2021  |  JOURNAL OF GENETIC COUNSELING

Increasing demand for clinical genetic services may impact the resources and quality of genetic counseling, potentially impacting ..

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

Hanla A Park, Sonja Neumeyer, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Adinda Baten, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, et al.

Journal article  |  2021  |  BRITISH JOURNAL OF CANCER

BACKGROUND: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies..

Metaphors and why these are important in all aspects of genetic counseling

Adrienne Sexton, Paul A James

Journal article  |  2021  |  JOURNAL OF GENETIC COUNSELING

Metaphors appear simple but are fundamental schemata allowing expression and processing of complex emotions and information. They ..

Genetic Dominant Variants in STUB1, Segregating in Families with SCA48, Display In Vitro Functional Impairments Indistinctive from Recessive Variants Associated with SCAR16

Yasaman Pakdaman, Siren Berland, Helene J Bustad, Sigrid Erdal, Bryony A Thompson, Paul A James, Kjersti N Power, Stale Ellingsen, Martin Krooni, Line I Berge, Adrienne Sexton, Laurence A Bindoff, Per M Knappskog, Stefan Johansson, Ingvild Aukrust

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Variants in STUB1 cause both autosomal recessive (SCAR16) and dominant (SCA48) spinocerebellar ataxia. Reports from 18 STUB1 varia..

Genetic testing in dementia-A medical genetics perspective

Aamira J Huq, Adrienne Sexton, Paul Lacaze, Colin L Masters, Elsdon Storey, Dennis Velakoulis, Paul A James, Ingrid M Winship

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

OBJECTIVE: When a genetic cause is suspected in a person with dementia, it creates unique diagnostic and management challenges to ..

CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

Nichola Johnson, Sarah Maguire, Anna Morra, Pooja Middha Kapoor, Katarzyna Tomczyk, Michael E Jones, Minouk J Schoemaker, Clare Gilham, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Caroline Baynes, Laura E Beane Freeman, et al.

Journal article  |  2021  |  BRITISH JOURNAL OF CANCER

BACKGROUND: Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cance..