Aung Ko Win

Potential impact of family history-based screening guidelines on the detection of early-onset colorectal cancer

Samir Gupta, Balambal Bharti, Dennis J Ahnen, Daniel D Buchanan, Iona C Cheng, Michelle Cotterchio, Jane C Figueiredo, Steven J Gallinger, Robert W Haile, Mark A Jenkins, Noralane M Lindor, Finlay A Macrae, Loic Le Marchand, Polly A Newcomb, Stephen N Thibodeau, Aung Ko Win, Maria Elena Martinez

Journal article  |  2020  |  Cancer

BACKGROUND: Initiating screening at an earlier age based on cancer family history is one of the primary recommended strategies for..

Cumulative Burden of Colorectal Cancer Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Alexi N Archambault, Yu-Ru Su, Jihyoun Jeon, Minta Thomas, Yi Lin, David V Conti, Aung Ko Win, Lori C Sakoda, Iris Lansdorp-Vogelaar, Elisabeth FP Peterse, Ann G Zauber, David Duggan, Andreana N Holowatyj, Jeroen R Huyghe, Hermann Brenner, Michelle Cotterchio, Stephane Bezieau, Stephanie L Schmit, Christopher K Edlund, Melissa C Southey, et al.

Journal article  |  2020  |  Gastroenterology

BACKGROUND & AIMS: Early-onset colorectal cancer (CRC, in persons younger than 50 years old) is increasing in incidence; yet, in t..

Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk.

Nikhil K Khankari, Barbara L Banbury, Maria C Borges, Philip Haycock, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stéphane Bézieau, Hermann Brenner, Peter T Campbell, Graham Casey, Andrew T Chan, Jenny Chang-Claude, David V Conti, Michelle Cotterchio, Dallas R English, Jane C Figueiredo, Graham G Giles, Edward L Giovannucci, Marc J Gunter, et al.

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: Results from epidemiologic studies examining polyunsaturated fatty acids (PUFA) and colorectal cancer risk are inconsi..

Genetic Predictors of Circulating 25-Hydroxyvitamin D and Prognosis after Colorectal Cancer.

Sonja Neumeyer, Katja Butterbach, Barbara L Banbury, Sonja I Berndt, Peter T Campbell, Rowan T Chlebowski, Andrew T Chan, Edward L Giovannucci, Amit D Joshi, Shuji Ogino, Mingyang Song, Marjorie L McCullough, Haifa Maalmi, JoAnn E Manson, Lori C Sakoda, Robert E Schoen, Martha L Slattery, Emily White, Aung K Win, Jane C Figueiredo, et al.

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

Background: Low serum 25-hydroxyvitamin D [25(OH)D] concentrations in patients with colorectal cancer have been consistently assoc..

A New Comprehensive Colorectal Cancer Risk Prediction Model Incorporating Family History, Personal Characteristics, and Environmental Factors

Yingye Zheng, Xinwei Hua, Aung K Win, Robert J MacInnis, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, John A Baron, John L Hopper, James G Dowty, Antonis C Antoniou, Jiayin Zheng, Mark A Jenkins, Polly A Newcomb

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

PURPOSE: Reducing colorectal cancer incidence and mortality through early detection would improve efficacy if targeted. We develop..

Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

Shimelis Dejene Gemechu, Christine M van Vliet, Aung Ko Win, Jane C Figueiredo, Loic Le Marchand, Steven Gallinger, Polly A Newcomb, John L Hopper, Noralane M Lindor, Mark A Jenkins, James G Dowty

Journal article  |  2020  |  Familial Cancer

Early-Age-of-Onset Colorectal Carcinoma: An Emerging Public Health Issue

Aung K Win, Garrett Friedman, Jose G Guillem

Book Chapter  |  2020

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Mev Dominguez-Valentin, Julian R Sampson, Toni T Seppala, Sanne W ten Broeke, John-Paul Plazzer, Sigve Nakken, Christoph Engel, Stefan Aretz, Mark A Jenkins, Lone Sunde, Inge Bernstein, Gabriel Capella, Francesc Balaguer, Huw Thomas, D Gareth Evans, John Burn, Marc Greenblatt, Eivind Hovig, Wouter H de Vos Tot Nederveen Cappel, Rolf H Sijmons, et al.

Journal article  |  2020  |  Genetics in Medicine

PURPOSE: Pathogenic variants affecting MLH1, MSH2, MSH6, and PMS2 cause Lynch syndrome and result in different but imprecisely kno..

Mortality after breast cancer as a function of time since diagnosis by estrogen receptor status and age at diagnosis

Harindra Jayasekara, Robert J MacInnis, James A Chamberlain, Gillian S Dite, Nicole M Leoce, James G Dowty, Adrian Bickerstaffe, Aung Ko Win, Roger L Milne, Graham G Giles, Mary Beth Terry, Diana M Eccles, Melissa C Southey, John L Hopper

Journal article  |  2019  |  International Journal of Cancer

Our aim was to estimate how long-term mortality following breast cancer diagnosis depends on age at diagnosis, tumor estrogen rece..

Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers

Peter Georgeson, Bernard Pope, Christophe Rosty, Mark Clendenning, Romy Walker, Khalid Mahmood, Jihoon Joo, Ryan Hutchinson, Susan Preston, Julia Como, Sharelle Joseland, Aung Ko Win, Finlay Macrae, John Hopper, Mark Jenkins, Ingrid Winship, Daniel Buchanan

Journal article  |  2019

Objective: Germline pathogenic variants (PVs) in the DNA mismatch repair (MMR) genes and the base excision repair genes NTHL1 and ..

Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome

S Ghazaleh Dashti, Wing Yan Li, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Sheetal Hardikar, Xinwei Hua, Stephen N Thibodeau, Jane C Figueiredo, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Noralane M Lindor, John L Hopper, et al.

Journal article  |  2019  |  British Journal of Cancer

BACKGROUND: Type 2 diabetes mellitus and high total cholesterol and triglycerides are known to be associated with increased colore..

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history

Mark A Jenkins, Aung K Win, James G Dowty, Robert J MacInnis, Enes Makalic, Daniel F Schmidt, Gillian S Dite, Mirosl Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Jon D Emery, Sibel Saya, Finlay A Macrae, Dennis J Ahnen, David Duggan, Jane C Figueiredo, Noralane M Lindor, Robert W Haile, John D Potter, et al.

Journal article  |  2019  |  Familial Cancer

Before SNP-based risk can be incorporated in colorectal cancer (CRC) screening, the ability of these SNPs to estimate CRC risk for..

Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families

Yun-Hee Choi, Lajmi Lakhal-Chaieb, Agnieszka Krol, Bing Yu, Daniel Buchanan, Dennis Ahnen, Loic Le Marchand, Polly A Newcomb, Aung Ko Win, Mark Jenkins, Noralane M Lindor, Laurent Briollais

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Background: The risk of cancers is well characterized in Lynch syndrome (LS) families but has been less studied in familial colore..

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

Philip J Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Aria Timofeeva, Peter Broderick, James Studd, Juan Fernandez-Tajes, Susan Farrington, Victoria Svinti, Claire Palles, Giulia Orlando, Amit Sud, Amy Holroyd, Steven Penegar, Evropi Theodoratou, Peter Vaughan-Shaw, Harry Campbell, Lina Zgaga, Caroline Hayward, Archie Campbell, et al.

Journal article  |  2019  |  Nature Communications

Cancer Risks for PMS2-Associated Lynch Syndrome (vol 29, pg 2961, 2018)

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, Liselotte van Hest, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, et al.

Artefact  |  2019  |  Journal of Clinical Oncology

Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization

Melisa YZ Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline J Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Graham Giles, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Katrina J Allen, Geza Benke, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, et al.

Journal article  |  2019  |  Clinical & Experimental Allergy

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Stephanie L Schmit, Christopher K Edlund, Fredrick R Schumacher, Jian Gong, Tabitha A Harrison, Jeroen R Huyghe, Chenxu Qu, Marilena Melas, David J Van den Berg, Hansong Wang, Stephanie Tring, Sarah J Plummer, Demetrius Albanes, M Henar Alonso, Christopher I Amos, Kristen Anton, Aaron K Aragaki, Volker Arndt, Elizabeth L Barry, Sonja I Berndt, et al.

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Lynch syndrome (hereditary nonpolyposis colorectal cancer): Cancer screening and management

Noralane Lindor, Aung Win

Book Chapter  |  2019

Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen R Huyghe, Stephanie A Bien, Tabitha A Harrison, Hyun Min Kang, Sai Chen, Stephanie L Schmit, David V Conti, Conghui Qu, Jihyoun Jeon, Christopher K Edlund, Peyton Greenside, Michael Wainberg, Fredrick R Schumacher, Joshua D Smith, David M Levine, Sarah C Nelson, Nasa A Sinnott-Armstrong, Demetrius Albanes, M Henar Alonso, Kristin Anderson, et al.

Journal article  |  2019  |  Nature Genetics

Physical activity and the risk of colorectal cancer in Lynch syndrome

S Ghazaleh Dashti, Aung Ko Win, Sheetal S Hardikar, Stephen E Glombicki, Sheila Mallenahalli, Selvi Thirumurthi, Susan K Peterson, Y Nancy You, Daniel D Buchanan, Jane C Figueiredo, Peter T Campbell, Steven Gallinger, Polly A Newcomb, John D Potter, Noralane M Lindor, Loic Le Marchand, Robert W Haile, John L Hopper, Mark A Jenkins, Karen M Basen-Engquist, et al.

Journal article  |  2018  |  International Journal of Cancer

Cancer Risks for PMS2-Associated Lynch Syndrome

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, Tom GW Letteboer, et al.

Journal article  |  2018  |  Journal of Clinical Oncology

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1

Daniel D Buchanan, Jenna R Stewart, Mark Clendenning, Christophe Rosty, Khalid Mahmood, Bernard J Pope, Mark A Jenkins, John L Hopper, Melissa C Southey, Finlay A Macrae, Ingrid M Winship, Aung Ko Win

Journal article  |  2018  |  Genet Med

Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

Sonja Neumeyer, Barbara L Banbury, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Stephanie A Bien, Dan D Buchanan, Katja Butterbach, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Stephen J Chanock, James Y Dai, Steven Gallinger, Edward L Giovannucci, Graham G Giles, William M Grady, Jochen Hampe, Michael Hoffmeister, et al.

Journal article  |  2018  |  British Journal of Cancer

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

Mala Pande, Aron Joon, Abenaa M Brewster, Wei V Chen, John L Hoppers, Cathy Eng, Sanjay Shete, Graham Casey, Fredrick Schumacher, Yi Lin, Tabitha A Harrison, Emily White, Habibul Ahsan, Irene L Andrulis, Alice S Whittemore, Esther M John, Aung Ko Win, Enes Makalic, Daniel F Schmidt, Miroslaw K Kapuscinski, et al.

Journal article  |  2018  |  PLOS ONE

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Mark A Jenkins, Aung Ko Win, Allyson S Templeton, Maggie S Angelakos, Daniel D Buchanan, Michelle Cotterchio, Jane C Figueiredo, Stephen N Thibodeau, John A Baron, John D Potter, John L Hopper, Graham Casey, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, Polly A Newcomb, Robert W Haile

Journal article  |  2018  |  International Journal of Epidemiology

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history

Mark Jenkins, Aung Win, James Dowty, Robert MacInnis, Enes Makalic, Daniel Schmidt, Gillian Dite, Miroslaw Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid Winship, Jon Emery, Sibel Saya, Finlay Macrae, Dennis Ahnen, David Duggan, Jane Figueiredo, Noralane Lindor, Robert Haile, John Potter, et al.

Journal article  |  2018

ABSTRACT Background A number of single nucleotide polymorphisms (SNPs), which are common inherited genetic variants, have been ide..

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

Harsh Sheth, Emma Northwood, Cornelia M Ulrich, Dominique Scherer, Faye Elliott, Jennifer H Barrett, David Forman, C Roland Wolf, Gillian Smith, Michael S Jackson, Mauro Santibanez-Koref, Robert Haile, Graham Casey, Mark Jenkins, Aung Ko Win, John L Hopper, Loic Le Marchand, Noralane M Lindor, Stephen N Thibodeau, John D Potter, et al.

Journal article  |  2018  |  PLOS ONE

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Tomas Tanskanen, Linda van den Berg, Niko Valimaki, Mervi Aavikko, Eivind Ness-Jensen, Kristian Hveem, Yvonne Wettergren, Elinor Bexe Lindskog, Neeme Tonisson, Andres Metspalu, Kaisa Silander, Giulia Orlando, Philip J Law, Sari Tuupanen, Alexandra E Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Johanna Kondelin, Antti-Pekka Sarin, Eero Pukkala, et al.

Journal article  |  2018  |  International Journal of Cancer

Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas

Mark Clendenning, Alvin Huang, Harindra Jayasekara, Marie Lorans, Susan Preston, Neil O'Callaghan, Bernard J Pope, Finlay A Macrae, Ingrid M Winship, Roger L Milne, Graham G Giles, Dallas R English, John L Hopper, Aung K Win, Mark A Jenkins, Melissa C Southey, Christophe Rosty, Daniel D Buchanan

Journal article  |  2018  |  Familial Cancer

The International Mismatch Repair Consortium

Mark A Jenkins, Jeanette C Reece, Aung K Win

Book Chapter  |  2018

Genetic and Environmental Modifiers of Cancer Risk in Lynch Syndrome

Aung K Win, Rodney J Scott

Book Chapter  |  2018

The Colon Cancer Family Registry Cohort

Mark A Jenkins, Aung K Win, Noralane M Lindor

Book Chapter  |  2018

Long-Term Weight Loss After Colorectal Cancer Diagnosis Is Associated With Lower Survival: The Colon Cancer Family Registry

Jonathan M Kocarnik, Xinwei Hua, Sheetal Hardikar, Jamaica Robinson, Noralane M Lindor, Aung Ko Win, John L Hopper, Jane C Figueiredo, John D Potter, Peter T Campbell, Steven Gallinger, Michelle Cotterchio, Scott V Adams, Stacey A Cohen, Amanda I Phipps, Polly A Newcomb

Journal article  |  2017  |  Cancer

Reproductive factors as risk modifiers of breast cancer in BRCA mutation carriers and high-risk non-carriers

Boyoung Park, John L Hopper, Aung K Win, James G Dowty, Ho Kyung Sung, Choonghyun Ahn, Sung-Won Kim, Min Hyuk Lee, Jihyoun Lee, Jong Won Lee, Eunyoung Kang, Jong-Han Yu, Ku Sang Kim, Byung-In Moon, Wonshik Han, Dong-Young Noh, Sue K Park

Journal article  |  2017  |  Oncotarget

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

Sebastian May-Wilson, Amit Sud, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2017  |  European Journal of Cancer

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes

Melissa S DeRycke, Shanaka Gunawardena, Jessica R Balcom, Angela M Pickart, Lindsey A Waltman, Amy J French, Shannon McDonnell, Shaun M Riska, Zachary C Fogarty, Melissa C Larson, Sumit Middha, Bruce W Eckloff, Yan W Asmann, Matthew J Ferber, Robert W Haile, Steven Gallinger, Mark Clendenning, Christophe Rosty, Aung K Win, Daniel D Buchanan, et al.

Journal article  |  2017  |  Molecular Genetics & Genomic Medicine

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Henry Rodriguez-Broadbent, Philip J Law, Amit Sud, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Samuli Ripatti, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Aarno Palotie, et al.

Journal article  |  2017  |  International Journal of Cancer

Findings in young adults at colonoscopy from a hospital service database audit

Stephanie Wong, Ilmars Lidums, Christophe Rosty, Andrew Ruszkiewicz, Susan Parry, Aung Ko Win, Yoko Tomita, Sina Vatandoust, Amanda Townsend, Dainik Patel, Jennifer E Hardingham, David Roder, Eric Smith, Paul Drew, Julie Marker, Wendy Uylaki, Peter Hewett, Daniel L Worthley, Erin Symonds, Graeme P Young, et al.

Journal article  |  2017  |  BMC Gastroenterology

Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer

Gillian S Dite, Robert J MacInnis, Adrian Bickerstaffe, James G Dowty, Roger L Milne, Antonis C Antoniou, Prue Weideman, Carmel Apicella, Graham G Giles, Melissa C Southey, Mark A Jenkins, Kelly-Anne Phillips, Aung Ko Win, Mary Beth Terry, John L Hopper

Journal article  |  2017  |  American Journal of Epidemiology

Prediagnostic Alcohol Consumption and Colorectal Cancer Survival: The Colon Cancer Family Registry

Amanda I Phipps, Jamaica R Robinson, Peter T Campbell, Aung Ko Win, Jane C Figueiredo, Noralane M Lindor, Polly A Newcomb

Journal article  |  2017  |  Cancer

The interaction between farming/rural environment and TLR2, TLR4, TLR6 and CD14 genetic polymorphisms in relation to early- and late-onset asthma

Melisa YZ Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Stephen Morrison, Graham G Giles, John Hopper, Michael J Abramson, E Haydn Walters, Melanie C Matheson

Journal article  |  2017  |  Scientific Reports

Reducing the polyp burden in serrated polyposis by serial colonoscopy: the impact of nationally coordinated community surveillance

Susan Parry, Randall W Burt, Aung Ko Win, Ye Kyaw Aung, Sonja Woodall, Julie Arnold, Mark Clendenning, Daniel D Buchanan, Timothy J Price, Christophe Rosty, Joanne P Young

Journal article  |  2017  |  The New Zealand medical journal

Germline miRNA DNA Variants and the Risk of Colorectal Cancer by Subtype

Noralane M Lindor, Melissa C Larson, Melissa S DeRycke, Shannon K McDonnell, Saurabh Baheti, Zachary C Fogarty, Aung Ko Win, John D Potter, Daniel D Buchanan, Mark Clendenning, Polly A Newcomb, Graham Casey, Steven Gallinger, Loic Le Marchand, John L Hopper, Mark A Jenkins, Ellen L Goode, Stephen N Thibodeau

Journal article  |  2017  |  Genes, Chromosomes and Cancer

Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Dennis J Ahnen, Stephen N Thibodeau, Graham Casey, Steven Gallinger, Loic Le Marchand, Robert W Haile, John D Potter, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Modeling of Successive Cancer Risks in Lynch Syndrome Families in the Presence of Competing Risks Using Copulas

Yun-Hee Choi, Laurent Briollais, Aung K Win, John Hopper, Dan Buchanan, Mark Jenkins, Lajmi Lakhal-Chaieb

Journal article  |  2017  |  Biometrics

Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers

S Ghazaleh Dashti, Daniel D Buchanan, Harindra Jayasekara, Driss Ait Ouakrim, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Susan Parry, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts

Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Stine V Eriksen, Michael D Walsh, Rhiannon J Walters, Stephen N Thibodeau, Jenna Stewart, Susan Preston, Aung Ko Win, Louisa Flander, Driss Ait Ouakrim, Finlay A Macrae, Alex Boussioutas, Ingrid M Winship, Graham G Giles, John L Hopper, Melissa C Southey, Dallas English, Mark A Jenkins

Journal article  |  2017  |  Journal of Gastroenterology and Hepatology

Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Dennis J Ahnen, Susan Parry, Mark A Jenkins, Aung Ko Win

Journal article  |  2017  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

High-risk familial syndromes

B Leggett, N Poplawski, C Rosty, I Norton, C Wright, A Win, F Macrae, undefined Cancer Council Australia Colorectal Cancer Guidelines Working Party

Book Chapter  |  2017

The optimal management of individuals with, or at risk of, a familial colorectal cancer syndrome is dependent upon determining whi..

Primary prevention

F Macrae, T Lockett, J Clarke, J Emery, M Jenkins, J McNeil, A Spigelman, A Win, R Woods, G Young, N Pachter, J Zalcbeg, undefined Cancer Council Australia Colorectal Cancer Guidelines Working Party

Book Chapter  |  2017

Colorectal cancer is the second most common non-skin cancer occurring in men and women in Australia, and the second most common ca..

Lynch syndrome (hereditary nonpolyposis colorectal cancer): Clinical manifestations and diagnosis

Aung Win, Noralane Lindor

Book Chapter  |  2017

SNP rs16906252C > T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer

Joice Kuroiwa-Trzmielina, Fan Wang, Robert W Rapkins, Robyn L Ward, Daniel D Buchanan, Aung Ko Win, Mark Clendenning, Christophe Rosty, Melissa C Southey, Ingrid M Winship, John L Hopper, Mark A Jenkins, Jake Olivier, Nicholas J Hawkins, Megan P Hitchins

Journal article  |  2016  |  Clinical Cancer Research

Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Aung Ko Win, Jeanette C Reece, James G Dowty, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Melissa C Southey, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, Finlay A Macrae, Katherine M Tucker, John A Baron, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer

Baiyu Yang, Aaron P Thrift, Jane C Figueiredo, Mark A Jenkins, Fredrick R Schumacher, David V Conti, Yi Lin, Aung Ko Win, Paul J Limburg, Sonja I Berndt, Hermann Brenner, Andrew T Chan, Jenny Chang-Claude, Michael Hoffmeister, Thomas J Hudson, Loic Le Marchand, Polly A Newcomb, Martha L Slattery, Emily White, Ulrike Peters, et al.

Journal article  |  2016  |  Cancer Epidemiology

Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

Khine Zin Oo, Ye Kyaw Aung, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  Australian & New Zealand Journal of Psychiatry

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Christophe Rosty, S Ghazaleh Dashti, Driss Ait Ouakrim, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Graham G Giles, Dennis J Ahnen, Jan Lowery, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Susan Parry, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status

Jie Shang, Jeanette C Reece, Daniel D Buchanan, Graham G Giles, Jane C Figueiredo, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  International Journal of Colorectal Disease

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

David Jarvis, Jonathan S Mitchell, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, et al.

Journal article  |  2016  |  British Journal of Cancer

The Experience of Extended Bowel Resection in Individuals With a High Metachronous Colorectal Cancer Risk: A Qualitative Study

Emma J Steel, Alison H Trainer, Alexander G Heriot, Craig Lynch, Susan Parry, Aung K Win, Louise A Keogh

Journal article  |  2016  |  Oncology Nursing Forum

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Giulia Orlando, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2016  |  Human Molecular Genetics

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Rowena Chau, Seyedeh Ghazaleh Dashti, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Finlay A Macrae, Alex Boussioutas, Susan Parry, Jane C Figueiredo, A Joan Levine, Dennis J Ahnen, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Determining the familial risk distribution of colorectal cancer: a data mining approach

Rowena Chau, Mark A Jenkins, Daniel D Buchanan, Driss Ait Ouakrim, Graham G Giles, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Aung Ko Win

Journal article  |  2016  |  Familial Cancer

GWASeq: targeted re-sequencing follow up to GWAS

Matthew P Salomon, Wai Lok Sibon Li, Christopher K Edlund, John Morrison, Barbara K Fortini, Aung Ko Win, David V Conti, Duncan C Thomas, David Duggan, Daniel D Buchanan, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Graham Casey, Paul Marjoram

Journal article  |  2016  |  BMC Genomics

Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer

Fay Kastrinos, Rohit P Ojha, Celine Leenen, Carmelita Alvero, Rowena C Mercado, Judith Balmana, Irene Valenzuela, Francesc Balaguer, Roger Green, Noralane M Lindor, Stephen N Thibodeau, Polly Newcomb, Aung Ko Win, Mark Jenkins, Daniel D Buchanan, Lucio Bertario, Paola Sala, Heather Hampel, Sapna Syngal, Ewout W Steyerberg

Journal article  |  2016  |  JNCI: Journal of the National Cancer Institute

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort

Christophe Rosty, Mark Clendenning, Michael D Walsh, Stine V Eriksen, Melissa C Southey, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Nicola K Poplawski, Susan Parry, Julie Arnold, Joanne P Young, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Melissa DeRycke, Noralane M Lindor, et al.

Journal article  |  2016  |  BMJ Open

Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening

Mark A Jenkins, Enes Makalic, James G Dowty, Daniel F Schmidt, Gillian S Dite, Robert J MacInnis, Driss Ait Ouakrim, Mark Clendenning, Louisa B Flander, Oliver K Stanesby, John L Hopper, Aung K Win, Daniel D Buchanan

Journal article  |  2016  |  Future Oncology

PMS2 monoallelic mutation carriers: the known unknown

McKinsey L Goodenberger, Brittany C Thomas, Douglas Riegert-Johnson, C Richard Boland, Sharon E Plon, Mark Clendenning, Aung Ko Win, Leigha Senter, Steven M Lipkin, Zsofia K Stadler, Finlay A Macrae, Henry T Lynch, Jeffrey N Weitzel, Albert de la Chapelle, Sapna Syngal, Patrick Lynch, Susan Parry, Mark A Jenkins, Steven Gallinger, Spring Holter, et al.

Journal article  |  2016  |  Genetics in Medicine

Risk Prediction Models for Colorectal Cancer: A Systematic Review

Juliet A Usher-Smith, Fiona M Walter, Jon D Emery, Aung K Win, Simon J Griffin

Journal article  |  2016  |  Cancer Prevention Research

Lynch syndrome and cervical cancer

Yoland C Antill, James G Dowty, Aung Ko Win, Tina Thompson, Michael D Walsh, Margaret C Cummings, Steven Gallinger, Noralane M Lindor, Loic Le Marchand, John L Hopper, Polly A Newcomb, Robert W Haile, James Church, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Ingrid M Winship, Mark A Jenkins

Journal article  |  2015  |  International Journal of Cancer

Childhood cancers in families with and without Lynch syndrome

John A Heath, Jeanette C Reece, Daniel D Buchanan, Graham Casey, Carol A Durno, Steven Gallinger, Robert W Haile, Polly A Newcomb, John D Potter, Stephen N Thibodeau, Loic Le Marchand, Noralane M Lindor, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2015  |  Familial Cancer

Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

Aung Ko Win, Jeanette C Reece, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, James G Dowty, Robert J MacInnis, Katherine M Tucker, Ingrid M Winship, Finlay A Macrae, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, Noralane M Lindor, et al.

Journal article  |  2015  |  Familial Cancer

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Timothy HT Cheng, Deborah Thompson, Jodie Painter, Tracy O'Mara, Maggie Gorman, Lynn Martin, Claire Palles, Angela Jones, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, Polly A Newcomb, Steve Gallinger, David Conti, Fred Schumacher, Graham Casey, Graham G Giles, Paul Pharoah, et al.

Journal article  |  2015  |  Scientific Reports

Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.

Aung Ko Win, Mark Clendenning, William Crawford, Christophe Rosty, Susan G Preston, Melissa C Southey, Susan Parry, Graham G Giles, Finlay A Macrae, Ingrid M Winship, John A Baron, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2015  |  Genes & Cancer

Lynch syndrome is an inherited cancer-predisposing disorder caused by germline mutations in the DNA mismatch repair (MMR) genes bu..

Incidence and prevalence of non-melanoma skin cancer in Australia: A systematic review

Eshini Perera, Neiraja Gnaneswaran, Carolyn Staines, Aung Ko Win, Rod Sinclair

Journal article  |  2015  |  Australasian Journal of Dermatology

Mutation Spectrum and Risk of Colorectal Cancer in African American Families with Lynch Syndrome

Rodrigo Santa Cruz Guindalini, Aung Ko Win, Cassandra Gulden, Noralane M Lindor, Polly A Newcomb, Robert W Haile, Victoria Raymond, Elena Stoffel, Michael Hall, Xavier Llor, Chinedu I Ukaegbu, Ilana Solomon, Jeffrey Weitzel, Matthew Kalady, Amie Blanco, Jonathan Terdiman, Gladis A Shuttlesworth, Patrick M Lynch, Heather Hampel, Henry T Lynch, et al.

Journal article  |  2015  |  Gastroenterology

Fertility after young-onset colorectal cancer: a study of subjects with Lynch syndrome

D Stupart, AK Win, IM Winship, M Jenkins

Journal article  |  2015  |  Colorectal Disease

Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome

Driss Ait Ouakrim, Seyedeh Ghazaleh Dashti, Rowena Chau, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Barbara Leggett, Finlay A Macrae, Dennis J Ahnen, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, et al.

Journal article  |  2015  |  Journal of the National Cancer Institute

Breast cancer risk for Korean women with germline mutations in BRCA1 and BRCA2

Boyoung Park, James G Dowty, Choonghyun Ahn, Aung K Win, Sung-Won Kim, Min Hyuk Lee, Jong Won Lee, Eunyoung Kang, John L Hopper, Sue K Park

Journal article  |  2015  |  Breast Cancer Research and Treatment

Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype

Peter T Campbell, Christina C Newton, Polly A Newcomb, Amanda I Phipps, Dennis J Ahnen, John A Baron, Daniel D Buchanan, Graham Casey, Sean P Cleary, Michelle Cotterchio, Alton B Farris, Jane C Figueiredo, Steven Gallinger, Roger C Green, Robert W Haile, John L Hopper, Mark A Jenkins, Loic Le Marchand, Karen W Makar, John R McLaughlin, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome

Seyedeh Ghazaleh Dashti, Rowena Chau, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Ingrid M Winship, Julie Arnold, Dennis J Ahnen, Robert W Haile, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Loic Le Marchand, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, et al.

Journal article  |  2015  |  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PIK3CA Somatic Mutation Status in Relation to Patient and Tumor Factors in Racial/Ethnic Minorities with Colorectal Cancer

Amanda I Phipps, Dennis J Ahnen, Iona Cheng, Polly A Newcomb, Aung Ko Win, Terrilea Burnett

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics

Sheetal Hardikar, Polly A Newcomb, Peter T Campbell, Aung Ko Win, Noralane M Lindor, Daniel D Buchanan, Karen W Makar, Mark A Jenkins, John D Potter, Amanda I Phipps

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk

Aaron P Thrift, Jian Gong, Ulrike Peters, Jenny Chang-Claude, Anja Rudolph, Martha L Slattery, Andrew T Chan, Adame Locke, Bratati Kahali, Anne E Justice, Tune H Pers, Steven Gallinger, Richard B Hayes, John A Baron, Bette J Caan, Shuji Ogino, Sonja I Berndt, Stephen J Chanock, Graham Casey, Robert W Haile, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

Mendelian randomization study of height and risk of colorectal cancer

Aaron P Thrift, Jian Gong, Ulrike Peters, Jenny Chang-Claude, Anja Rudolph, Martha L Slattery, Andrew T Chan, Tonu Esko, Andrew R Wood, Jian Yang, Sailaja Vedantam, Stefan Gustafsson, Tune H Pers, John A Baron, Stephane Bezieau, Sebastien Kuery, Shuji Ogino, Sonja I Berndt, Graham Casey, Robert W Haile, et al.

Journal article  |  2015  |  International Journal of Epidemiology

Short-Term Risk of Colorectal Cancer in Individuals With Lynch Syndrome: A Meta-Analysis

Mark A Jenkins, James G Dowty, Driss Ait Ouakrim, John D Mathews, John L Hopper, Youenn Drouet, Christine Lasset, Valerie Bonadona, Aung Ko Win

Journal article  |  2015  |  Journal of Clinical Oncology

Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

Aung Ko Win, Daniel D Buchanan, Christophe Rosty, Robert J MacInnis, James G Dowty, Gillian S Dite, Graham G Giles, Melissa C Southey, Joanne P Young, Mark Clendenning, Michael D Walsh, Rhiannon J Walters, Alex Boussioutas, Thomas C Smyrk, Stephen N Thibodeau, John A Baron, John D Potter, Polly A Newcomb, Loic Le Marchand, Robert W Haile, et al.

Journal article  |  2015  |  Gut

Rising incidence of early-onset colorectal cancer in Australia over two decades: Report and review

Joanne P Young, Aung Ko Win, Christophe Rosty, Ingrid Flight, David Roder, Graeme P Young, Oliver Frank, Graeme K Suthers, Peter J Hewett, Andrew Ruszkiewicz, Ehud Hauben, Barbara-Ann Adelstein, Susan Parry, Amanda Townsend, Jennifer E Hardingham, Timothy J Price

Journal article  |  2015  |  Journal of Gastroenterology and Hepatology

Family History and Risk of Endometrial Cancer A Systematic Review and Meta-analysis

Aung Ko Win, Jeanette C Reece, Shae Ryan

Journal article  |  2015  |  Obstetrics & Gynecology

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

Christophe Rosty, Michael D Walsh, Noralane M Lindor, Stephen N Thibodeau, Erin Mundt, Steven Gallinger, Melyssa Aronson, Aaron Pollett, John A Baron, Sally Pearson, Mark Clendenning, Rhiannon J Walters, Belinda N Nagler, William J Crawford, Joanne P Young, Ingrid Winship, Aung Ko Win, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2014  |  Familial Cancer

Should the grading of colorectal adenocarcinoma include microsatellite instability status?

Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Rhiannon J Walters, Aung K Win, Mark A Jenkins, John L Hopper, Ingrid M Winship, Melissa C Southey, Graham G Giles, Dallas R English, Daniel D Buchanan

Journal article  |  2014  |  Human Pathology

Fertility and apparent genetic anticipation in Lynch syndrome

Douglas Stupart, Aung Ko Win, Mark Jenkins, Ingrid M Winship, Paul Goldberg, Rajkumar Ramesar

Journal article  |  2014  |  Familial Cancer

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Nicola Whiffin, Fay J Hosking, Susan M Farrington, Claire Palles, Sara E Dobbins, Lina Zgaga, Amy Lloyd, Ben Kinnersley, Maggie Gorman, Albert Tenesa, Peter Broderick, Yufei Wang, Ella Barclay, Caroline Hayward, Lynn Martin, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, et al.

Journal article  |  2014  |  Human Molecular Genetics

Re: Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication

Christophe Rosty, Elizabeth J Wiliamson, Mark Clendening, Rhianon J Walters, Michael D Walsh, Aung K Win, Mark A Jenkins, John L Hoper, Ingrid Winship, Melisa C Southey, Graham G Giles, Dalas R English, Daniel D Buchanan

Journal article  |  2014  |  JNCI Journal of the National Cancer Institute

Family History of Colorectal Cancer Is Not Associated with Colorectal Cancer Survival Regardless of Microsatellite Instability Status

Amanda I Phipps, Dennis J Ahnen, Peter T Campbell, Aung Ko Win, Mark A Jenkins, Noralane M Lindor, Robert Gryfe, John D Potter, Polly A Newcomb

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer

S Shiovitz, WK Copeland, MN Passarelli, AN Burnett-Hartman, WM Grady, JD Potter, S Gallinger, DD Buchanan, C Rosty, AK Win, M Jenkins, SN Thibodeau, R Haile, JA Baron, LL Marchand, PA Newcomb, NM Lindor

Journal article  |  2014  |  British Journal of Cancer

Genetic Variation in UGT Genes Modify the Associations of NSAIDs with Risk of Colorectal Cancer: Colon Cancer Family Registry

Dominique Scherer, Lisel M Koepl, Elizabeth M Poole, Yesilda Balavarca, Liren Xiao, John A Baron, Li Hsu, Anna E Coghill, Peter T Campbell, Sarah E Kleinstein, Jane C Figueiredo, Johanna W Lampe, Katharina Buck, John D Potter, Richard J Kulmacz, Mark A Jenkins, John L Hopper, Aung K Win, Polly A Newcomb, Cornelia M Ulrich, et al.

Journal article  |  2014  |  Genes, Chromosomes & Cancer

Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Rajani Bharati, Mark A Jenkins, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, Aung Ko Win

Journal article  |  2014  |  Gynecologic Oncology

Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, With and Without a Family History of Cancer

Aung Ko Win, James G Dowty, Sean P Cleary, Hyeja Kim, Daniel D Buchanan, Joanne P Young, Mark Clendenning, Christophe Rosty, Robert J MacInnis, Graham G Giles, Alex Boussioutas, Finlay A Macrae, Susan Parry, Jack Goldblatt, John A Baron, Terrilea Burnett, Loic Le Marchand, Polly A Newcomb, Robert W Haile, John L Hopper, et al.

Journal article  |  2014  |  Gastroenterology

Colorectal cancer and self-reported tooth agenesis

Noralane M Lindor, Aung Ko Win, Steven Gallinger, Darshana Daftary, Stephen N Thibodeau, Renato Silva, Ariadne Letra

Journal article  |  2014  |  Hereditary Cancer in Clinical Practice

Risk of Prostate Cancer in Lynch Syndrome: A Systematic Review and Meta-analysis

Shae Ryan, Mark A Jenkins, Aung Ko Win

Journal article  |  2014  |  Cancer Epidemiology, Biomarkers & Prevention

Perceived Versus Predicted Risks of Colorectal Cancer and Self-Reported Colonoscopies by Members of Mismatch Repair Gene Mutation-Carrying Families Who Have Declined Genetic Testing

Louisa Flander, Andrew Speirs-Bridge, Alison Rutstein, Heather Niven, Aung Ko Win, Driss Ait Ouakrim, John L Hopper, Finlay Macrae, Louise Keogh, Clara Gaff, Mark Jenkins

Journal article  |  2014  |  Journal of Genetic Counseling

Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome).

Daniel D Buchanan, Christophe Rosty, Mark Clendenning, Amanda B Spurdle, Aung Ko Win

Journal article  |  2014  |  Application of Clinical Genetics

Carriers of a germline mutation in one of the DNA mismatch repair (MMR) genes have a high risk of developing numerous different ca..

Risk profiling: Familial colorectal cancer

AK Win, DA Ouakrim, MA Jenkins

Journal article  |  2014  |  Cancer Forum

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype

Michael D Walsh, Mark Clendenning, Elizabeth Williamson, Sally-Ann Pearson, Rhiannon J Walters, Belinda Nagler, David Packenas, Aung K Win, John L Hopper, Mark A Jenkins, Andrew M Haydon, Christophe Rosty, Dallas R English, Graham G Giles, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Criteria and prediction models for mismatch repair gene mutations: a review

Aung Ko Win, Robert J MacInnis, James G Dowty, Mark A Jenkins

Journal article  |  2013  |  Journal of Medical Genetics

Re: Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome Response

Aung Ko Win, Mark A Jenkins

Journal article  |  2013  |  Journal of the National Cancer Institute

BRAFV600E Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome

Christopher W Toon, Michael D Walsh, Angela Chou, David Capper, Adele Clarkson, Loretta Sioson, Stephen Clarke, Scott Mead, Rhiannon J Walters, Mark Clendenning, Christophe Rosty, Joanne P Young, Aung Ko Win, John L Hopper, Ashley Crook, Andreas von Deimling, Mark A Jenkins, Daniel D Buchanan, Anthony J Gill

Journal article  |  2013  |  American Journal of Surgical Pathology

Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid?

Aung Ko Win, Mark A Jenkins

Journal article  |  2013  |  International Journal of Cancer

Differential effects of phosphate binders on pre-dialysis serum bicarbonate in end-stage kidney disease patients on maintenance haemodialysis

Zaw Thet, Aung Ko Win, Eugenie Pedagogos, Jennifer Beavis, Sandra Crikis, Craig Nelson

Journal article  |  2013  |  BMC Nephrology

Is prostate cancer a Lynch syndrome cancer?

Aung Ko Win

Journal article  |  2013  |  Asian Journal of Andrology

Colon and Rectal Cancer Survival by Tumor Location and Microsatellite Instability: The Colon Cancer Family Registry

Amanda I Phipps, Noralane M Lindor, Mark A Jenkins, John A Baron, Aung Ko Win, Steven Gallinger, Robert Gryfe, Polly A Newcomb

Journal article  |  2013  |  Diseases of the Colon and Rectum

Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer

Mohammad R Akbari, Laura N Anderson, Daniel D Buchanan, Mark Clendenning, Mark A Jenkins, Aung Ko Win, John L Hopper, Graham G Giles, Robert Nam, Steven Narod, Steven Gallinger, Sean P Cleary

Journal article  |  2013  |  Cancer Epidemiology

Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer

Rhiannon J Walters, Elizabeth J Williamson, Dallas R English, Joanne P Young, Christophe Rosty, Mark Clendenning, Michael D Walsh, Susan Parry, Dennis J Ahnen, John A Baron, Aung Ko Win, Graham G Giles, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2013  |  Epigenetics

Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome

Mark Clendenning, Joanne P Young, Michael D Walsh, Sonja Woodall, Julie Arnold, Mark Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Steven Gallinger, Christophe Rosty, Susan Parry, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Kristy Sanderson, Rhiannon J Walters, Susan Parry, Mark A Jenkins, Aung Ko Win, Melissa C Southey, John L Hopper, Graham G Giles, Elizabeth J Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

Dilemma in Pulmonary Metastasectomy Video-Assisted Thoracoscopic Surgery or Thoracotomy? Response

Jens Eckardt, Peter Bjorn Licht

Journal article  |  2013  |  Chest

Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Rhiannon J Walters, Sally Pearson, Erika Pavluk, Belinda Nagler, David Pakenas, Jeremy R Jass, Mark A Jenkins, Aung Ko Win, Melissa C Southey, Susan Parry, John L Hopper, Graham G Giles, Elizabeth Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers

Aung Ko Win, Susan Parry, Bryan Parry, Matthew F Kalady, Finlay A Macrae, Dennis J Ahnen, Graeme P Young, Lara Lipton, Ingrid Winship, Alex Boussioutas, Joanne P Young, Daniel D Buchanan, Julie Arnold, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  Annals of Surgical Oncology

Family History of Colorectal Cancer in BRAF p.V600E-Mutated Colorectal Cancer Cases

Daniel D Buchanan, Aung K Win, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Belinda Nagler, Sally-Ann Pearson, Finlay A Macrae, Susan Parry, Julie Arnold, Ingrid Winship, Graham G Giles, Noralane M Lindor, John D Potter, John L Hopper, Christophe Rosty, Joanne P Young, Mark A Jenkins

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Aung Ko Win, John L Hopper, Daniel D Buchanan, Joanne P Young, Albert Tenesa, James G Dowty, Graham G Giles, Jack Goldblatt, Ingrid Winship, Alex Boussioutas, Graeme P Young, Susan Parry, John A Baron, David Duggan, Steven Gallinger, Polly A Newcomb, Robert W Haile, Loic Le Marchand, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  European Journal of Cancer

KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers

AI Phipps, DD Buchanan, KW Makar, AK Win, JA Baron, NM Lindor, JD Potter, PA Newcomb

Journal article  |  2013  |  British Journal of Cancer

Multiplicity and Molecular Heterogeneity of Colorectal Carcinomas in Individuals With Serrated Polyposis

Christophe Rosty, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Sally-Ann Pearson, Mark A Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Kathy Tucker, Sian Greening, Michael R Gattas, Sonja Woodall, Julie Arnold, Neal I Walker, Susan Parry, et al.

Journal article  |  2013  |  American Journal of Surgical Pathology

Cancer Risks for MLH1 and MSH2 Mutation Carriers

James G Dowty, Aung K Win, Daniel D Buchanan, Noralane M Lindor, Finlay A Macrae, Mark Clendenning, Yoland C Antill, Stephen N Thibodeau, Graham Casey, Steve Gallinger, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Graeme P Young, Paul A James, Graham G Giles, Shanaka R Gunawardena, Barbara A Leggett, Michael Gattas, Alex Boussioutas, et al.

Journal article  |  2013  |  Human Mutation

Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Ingrid Winship, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Christophe Rosty, Barbara Leggett, Graham G Giles, Jack Goldblatt, Finlay A Macrae, Susan Parry, Matthew F Kalady, John A Baron, Dennis J Ahnen, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2013  |  Journal of the National Cancer Institute

Cancer risks for people with colorectal cancer-predisposing genetic mutations

A WIN

Thesis / Dissertation  |  2013

Background: Colorectal cancer is one of the most frequently diagnosed cancers in the world. On average, 1 in 20 people will be dia..

Risk of breast cancer in Lynch syndrome: a systematic review

Aung Ko Win, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  Breast Cancer Research

The Australasian Colorectal Cancer Family Registry Reducing the impact of colorectal cancer

Ingrid Winship, Aung Ko Win

Journal article  |  2012  |  Medical Journal of Australia

BRAF Mutation Status and Survival after Colorectal Cancer Diagnosis According to Patient and Tumor Characteristics

Amanda I Phipps, Daniel D Buchanan, Karen W Makar, Andrea N Burnett-Hartman, Anna E Coghill, Michael N Passarelli, John A Baron, Dennis J Ahnen, Aung Ko Win, John D Potter, Polly A Newcomb

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention

Risks of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Joanne P Young, Finlay A Macrae, Graeme P Young, Elizabeth Williamson, Susan Parry, Jack Goldblatt, Lara Lipton, Ingrid Winship, Barbara Leggett, Katherine M Tucker, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Julie Arnold, A Joan Levine, Robert W Haile, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of the National Cancer Institute

Phenotype and Polyp Landscape in Serrated Polyposis Syndrome: A Series of 100 Patients From Genetics Clinics

Christophe Rosty, Daniel D Buchanan, Michael D Walsh, Sally-Ann Pearson, Erika Pavluk, Rhiannon J Walters, Mark Clendenning, Kevin J Spring, Mark A Jenkins, Aung K Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Sonja Woodall, Julie Arnold, Neal I Walker, Jeremy R Jass, et al.

Journal article  |  2012  |  American Journal of Surgical Pathology

Kaplan-Meier failure estimate for metachronous colorectal cancer risk is clinically relevant

Mark A Jenkins, Lyle C Gurrin, Susan Parry, Aung Ko Win

Journal article  |  2012  |  Gut

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

Michael D Walsh, Daniel D Buchanan, Sally-Ann Pearson, Mark Clendenning, Mark A Jenkins, Aung Ko Win, Rhiannon J Walters, Kevin J Spring, Belinda Nagler, Erika Pavluk, Sven T Arnold, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, John L Hopper, Jeremy R Jass, John A Baron, Dennis J Ahnen, Stephen N Thibodeau, et al.

Journal article  |  2012  |  Modern Pathology

Cancer Risks for Relatives of Patients With Serrated Polyposis

Aung Ko Win, Rhiannon J Walters, Daniel D Buchanan, Mark A Jenkins, Kevin Sweet, Wendy L Frankel, Albert de la Chapelle, Diane M McKeone, Michael D Walsh, Mark Clendenning, Sally-Ann Pearson, Erika Pavluk, Belinda Nagler, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2012  |  American Journal of Gastroenterology

Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study

Aung Ko Win, Joanne P Young, Noralane M Lindor, Katherine M Tucker, Dennis J Ahnen, Graeme P Young, Daniel D Buchanan, Mark Clendenning, Graham G Giles, Ingrid Winship, Finlay A Macrae, Jack Goldblatt, Melissa C Southey, Julie Arnold, Stephen N Thibodeau, Shanaka R Gunawardena, Bharati Bapat, John A Baron, Graham Casey, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of Clinical Oncology

Risk Prediction Models for Colorectal Cancer: A Review

Aung Ko Win, Robert J MacInnis, John L Hopper, Mark A Jenkins

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention

Increased Cancer Risks in Myotonic Dystrophy

Aung Ko Win, Promilla G Perattur, Jose S Pulido, Christine M Pulido, Noralane M Lindor

Journal article  |  2012  |  Mayo Clinic Proceedings

Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry

A Joan Levine, Aung Ko Win, Daniel D Buchanan, Mark A Jenkins, John A Baron, Joanne P Young, Tiffany I Long, Daniel J Weisenberger, Peter W Laird, Rebecca L McCall, David J Duggan, Robert W Haile

Journal article  |  2012  |  Cancer prevention research

Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers

JL Hopper, MA Jenkins, JG Dowty, GS Dite, C Apicella, L Keogh, AK Win, JP Young, D Buchanan, MD Walsh, C Rosty, L Baglietto, G Severi, KA Phillips, EM Wong, A Dobrovic, P Waring, I Winship, SJ Ramus, GG Giles, et al.

Journal article  |  2012  |  Pathology

Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer

Aung Ko Win, Sean P Cleary, James G Dowty, John A Baron, Joanne P Young, Daniel D Buchanan, Melissa C Southey, Terrilea Burnett, Patrick S Parfrey, Roger C Green, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, John L Hopper, Steven Gallinger, Mark A Jenkins

Journal article  |  2011  |  International Journal of Cancer

Determining the frequency of de novo germline mutations in DNA mismatch repair genes

Aung Ko Win, Mark A Jenkins, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Graham G Giles, Jack Goldblatt, Barbara A Leggett, John L Hopper, Stephen N Thibodeau, Noralane M Lindor

Journal article  |  2011  |  Journal of Medical Genetics

Estimates of familial risks from family data are biased when ascertainment of families is not independent of family history

Aung Ko Win, John L Hopper, Mark A Jenkins

Journal article  |  2011  |  Gut

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery

Susan Parry, Aung Ko Win, Bryan Parry, Finlay A Macrae, Lyle C Gurrin, James M Church, John A Baron, Graham G Giles, Barbara A Leggett, Ingrid Winship, Lara Lipton, Graeme P Young, Joanne P Young, Caroline J Lodge, Melissa C Southey, Polly A Newcomb, Loic Le Marchand, Robert W Haile, Noralane M Lindor, Steven Gallinger, et al.

Journal article  |  2011  |  Gut

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

AK Win, JG Dowty, DR English, PT Campbell, JP Young, I Winship, FA Macrae, L Lipton, S Parry, GP Young, DD Buchanan, ME Martinez, ET Jacobs, DJ Ahnen, RW Haile, G Casey, JA Baron, NM Lindor, SN Thibodeau, PA Newcomb, et al.

Journal article  |  2011  |  British Journal of Cancer

Body Mass Index in Early Adulthood and Endometrial Cancer Risk for Mismatch Repair Gene Mutation Carriers

Aung Ko Win, James G Dowty, Yoland C Antill, Dallas R English, John A Baron, Joanne P Young, Graham G Giles, Melissa C Southey, Ingrid Winship, Lara Lipton, Susan Parry, Stephen N Thibodeau, Robert W Haile, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, Polly A Newcomb, John L Hopper, Mark A Jenkins

Journal article  |  2011  |  Obstetrics and Gynecology

Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis

Aung Ko Win, John L Hopper, Mark A Jenkins

Journal article  |  2011  |  Familial Cancer

Refugee status report

GA Paxton, NL Smith, AK Win, N Mulholland, DS Hood

Report  |  2011

A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants

E Theodoratou, H Campbell, A Tenesa, R Houlston, E Webb, S Lubbe, P Broderick, S Gallinger, EM Croitoru, MA Jenkins, AK Win, SP Cleary, T Koessler, PD Pharoah, S Kuery, S Bezieau, B Buecher, NA Ellis, P Peterlongo, K Offit, et al.

Journal article  |  2010  |  British Journal of Cancer

Risk Factors for Colorectal Cancer in Patients with Multiple Serrated Polyps: A Cross-Sectional Case Series from Genetics Clinics

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Dallas R English, Michael D Walsh, Mark Clendenning, Diane M McKeone, Rhiannon J Walters, Aedan Roberts, Sally-Ann Pearson, Erika Pavluk, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2010  |  PLoS One

Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Michael Gattas, Michael D Walsh, Mark Clendenning, Diane McKeone, Rhiannon Walters, Aedan Roberts, Alasdair Young, Heather Hampel, John L Hopper, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Elizabeth Chow, et al.

Journal article  |  2010  |  International Journal of Colorectal Disease

The State of Victoria's Children Report 2008

S Hood, J Cleary, A Farooqui, S Gabriel, L Hayes, M Hecker, AK WIN, H Molaeb, B Woolley

Report  |  2009

Response

AV Alexandrov, CF Bladin, R Maggisano, JW Norris

Journal article  |  1994  |  JNCI: Journal of the National Cancer Institute