Chi Luu

Subthreshold Nanosecond Laser in Age-Related Macular Degeneration: Observational Extension Study to the LEAD Clinical Trial

Zhichao Wu, Fred Kuanfu Chen, Lauren AB Hodgson, Emily Caruso, Colin A Harper, Sanjeewa S Wickremashinghe, Amy C Cohn, Pyrawy Sivarajah, Nicole Tindill, Chi D Luu, Robyn H Guymer

Journal article  |  2021  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

PURPOSE: To evaluate the long-term effect of subthreshold nanosecond laser (SNL) treatment on progression to late age-related macu..

Classifying Retinal Degeneration in Histological Sections Using Deep Learning

Daniel Al Mouiee, Erik Meijering, Michael Kalloniatis, Lisa Nivison-Smith, Richard A Williams, David AX Nayagam, Thomas C Spencer, Chi D Luu, Ceara McGowan, Stephanie B Epp, Mohit N Shivdasani

Journal article  |  2021  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Purpose: Artificial intelligence (AI) techniques are increasingly being used to classify retinal diseases. In this study we invest..

Examining the added value of microperimetry and low luminance deficit for predicting progression in age-related macular degeneration

Zhichao Wu, Chi D Luu, Lauren Ab Hodgson, Emily Caruso, Fred K Chen, Usha Chakravarthy, Jennifer J Arnold, Wilson J Heriot, Jim Runciman, Robyn H Guymer

Journal article  |  2021  |  BRITISH JOURNAL OF OPHTHALMOLOGY

PURPOSE: To examine the added predictive value of microperimetric sensitivity and low luminance deficit (LLD; difference between p..

USING MICROPERIMETRY AND LOW-LUMINANCE VISUAL ACUITY TO DETECT THE ONSET OF LATE AGE-RELATED MACULAR DEGENERATION A LEAD Study Report

Zhichao Wu, Chi D Luu, Lauren AB Hodgson, Emily Caruso, Fred K Chen, Usha Chakravarthy, Jennifer J Arnold, Wilson J Heriot, Jim Runciman, Robyn H Guymer

Journal article  |  2021  |  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

PURPOSE: To evaluate the performance of microperimetry and low-luminance visual acuity for detecting late age-related macular dege..

New Technologies to Study Functional Genomics of Age-Related Macular Degeneration

Tu Nguyen, Daniel Urrutia-Cabrera, Roxanne Hsiang-Chi Liou, Chi D Luu, Robyn Guymer, Raymond Ching-Bong Wong

Journal article  |  2021  |  FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in people over 50 years old in develop..

Human Dental Pulp Stem Cells (DPSCs) Therapy in Rescuing Photoreceptors and Establishing a Sodium Iodate-Induced Retinal Degeneration Rat Model

Chenshen Lam, Hiba Amer Alsaeedi, Avin Ee-Hwan Koh, Mohd Hairul Nizam Harun, Angela Ng Min Hwei, Pooi Ling Mok, Chi D Luu, Then Kong Yong, Suresh Kumar Subbiah, Mae-Lynn Catherine Bastion

Journal article  |  2021  |  TISSUE ENGINEERING AND REGENERATIVE MEDICINE

BACKGROUND: Different methods have been used to inject stem cells into the eye for research. We previously explored the intravitre..

Oculomotor Responses to Dynamic Stimuli in a 44-Channel Suprachoroidal Retinal Prosthesis

Samuel A Titchener, Jessica Kvansakul, Mohit N Shivdasani, James B Fallon, DAX Nayagam, Stephanie B Epp, Chris E Williams, Nick Barnes, William G Kentler, Maria Kolic, Elizabeth K Baglin, Lauren N Ayton, Carla J Abbott, Chi D Luu, Penelope J Allen, Matthew A Petoe

Journal article  |  2020  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Purpose: To investigate oculomotor behavior in response to dynamic stimuli in retinal implant recipients. Methods: Three suprachor..

Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images

Sarah Thiele, Ben Isselmann, Maximilian Pfau, Frank G Holz, Steffen Schmitz-Valckenberg, Zhichao Wu, Robyn H Guymer, Chi D Luu

Journal article  |  2020  |  TRANSLATIONAL VISION SCIENCE & TECHNOLOGY

Purpose: Relative ellipsoid zone reflectivity (rEZR) represents a potential biomarker of photoreceptor health on spectral-domain o..

Characterising the orientation-specific pattern-onset visual evoked potentials in children with bilateral refractive amblyopia and non-amblyopic controls

Tiong Peng Yap, Chi D Luu, Catherine M Suttle, Audrey Chia, Mei Ying Boon

Journal article  |  2020  |  DOCUMENTA OPHTHALMOLOGICA

PURPOSE: An orientation-specific visual evoked potential (osVEP) protocol was developed to probe meridional anisotropies in childr..

Comparison of CRISPR/Cas Endonucleases forin vivoRetinal Gene Editing

Fan Li, Kristof Wing, Jiang-Hui Wang, Chi D Luu, James A Bender, Jinying Chen, Qi Wang, Qinyi Lu, Minh Thuan Nguyen Tran, Kaylene M Young, Raymond CB Wong, Alice Pebay, Anthony L Cook, Sandy SC Hung, Guei-Sheung Liu, Alex W Hewitt

Journal article  |  2020  |  FRONTIERS IN CELLULAR NEUROSCIENCE

CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demons..