Eleanor Ager

Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo.

Alexander J Stevenson, Eleanor I Ager, Martina A Proctor, Dubravka Škalamera, Andrew Heaton, David Brown, Brian G Gabrielli

Journal article  |  2018  |  Scientific Reports

Successive rounds of chemical modification in three generations of benzopyran molecules have shown to select for different mechani..

Regulation of colorectal cancer cell epithelial to mesenchymal transition by the renin angiotensin system

Linh Nguyen, Eleanor I Ager, Jaclyn Neo, Christopher Christophi

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

Blockade of MMP14 Activity in Murine Breast Carcinomas: Implications for Macrophages, Vessels, and Radiotherapy

Eleanor I Ager, Sergey V Kozin, Nathaniel D Kirkpatrick, Giorgio Seano, David P Kodack, Vasileios Askoxylakis, Yuhui Huang, Shom Goel, Matija Snuderl, Alona Muzikansky, Dianne M Finkelstein, Daniel T Dransfield, Laetitia Devy, Yves Boucher, Dai Fukumura, Rakesh K Jain

Journal article  |  2015  |  JNCI: Journal of the National Cancer Institute

Blockade of the renin-angiotensin system inhibits growth of colorectal cancer liver metastases in the regenerating liver

Shir Lin Koh, EI Ager, PLN Costa, C Malcontenti-Wilson, V Muralidharan, C Christophi

Journal article  |  2014  |  Clinical and Experimental Metastasis

Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression.

Shom Goel, Nisha Gupta, Brian P Walcott, Matija Snuderl, Cristina T Kesler, Nathaniel D Kirkpatrick, Takahiro Heishi, Yuhui Huang, John D Martin, Eleanor Ager, Rekha Samuel, Shuhan Wang, John Yazbek, Benjamin J Vakoc, Randall T Peterson, Timothy P Padera, Dan G Duda, Dai Fukumura, Rakesh K Jain

Journal article  |  2013  |  Journal of the National Cancer Institute

BACKGROUND: The solid tumor microvasculature is characterized by structural and functional abnormality and mediates several delete..

The renin angiotensin system regulates Kupffer cells in colorectal liver metastases

Shu Wen Wen, Eleanor I Ager, Jaclyn Neo, Christopher Christophi

Journal article  |  2013  |  Cancer Biology & Therapy

Bimodal role of Kupffer cells during colorectal cancer liver metastasis

Shu Wen Wen, Eleanor I Ager, Christopher Christophi

Journal article  |  2013  |  Cancer Biology & Therapy

Blockade of the renin-angiotensin system improves the early stages of liver regeneration and liver function

Shir Lin Koh, Eleanor Ager, Cathy Malcontenti-Wilson, Vijayaragavan Muralidharan, Christopher Christophi

Journal article  |  2013  |  Journal of Surgical Research

Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases.

David P Kodack, Euiheon Chung, Hiroshi Yamashita, Joao Incio, Annique MMJ Duyverman, Youngchul Song, Christian T Farrar, Yuhui Huang, Eleanor Ager, Walid Kamoun, Shom Goel, Matija Snuderl, Alisha Lussiez, Lotte Hiddingh, Sidra Mahmood, Bakhos A Tannous, April F Eichler, Dai Fukumura, Jeffrey A Engelman, Rakesh K Jain

Journal article  |  2012  |  Proc Natl Acad Sci U S A

Brain metastases are a serious obstacle in the treatment of patients with human epidermal growth factor receptor-2 (HER2)-amplifie..

Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation

Eleanor I Ager, Shu Wen Wen, Joyna Chan, Way W Chong, Jaclyn H Neo, Christopher Christophi

Journal article  |  2011  |  BMC Cancer

Liver regeneration and tumour stimulation: implications of the renin-angiotensin system

Shir Lin Koh, Eleanor I Ager, Christopher Christophi

Journal article  |  2010  |  Liver International

Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases (vol 10, pg 19, 2010)

Eleanor I Ager, Way W Chong, Shu-Wen Wen, Christopher Christophi

Journal article  |  2010  |  Cancer Cell International

Targeting the the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases

Eleanor I Ager, Way W Chong, Shu-wen Wen, Christopher Christophi

Journal article  |  2010  |  Cancer Cell International

Changes in the renin angiotensin system during the development of colorectal cancer liver metastases

Jaclyn H Neo, Eleanor I Ager, Peter W Angus, Jin Zhu, Chandana B Herath, Christopher Christophi

Journal article  |  2010  |  BMC Cancer

Analysis of the platypus genome suggests a transposon origin for mammalian imprinting

Andrew J Pask, Anthony T Papenfuss, Eleanor I Ager, Kaighin A Mccoll, Terence P Speed, Marilyn B Renfree

Journal article  |  2009  |  Genome Biology

The renin angiotensin system as a modulator of colorectal cancer liver metastases

EI Ager, J Neo, C Christophi

Journal article  |  2008  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The renin-angiotensin system and malignancy

Eleanor I Ager, Jaclyn Neo, Christopher Christophi

Journal article  |  2008  |  Carcinogenesis

Evolution of the CDKN1C-KCNQ1 imprinted domain

Eleanor I Ager, Andrew J Pask, Helen M Gehring, Geoff Shaw, Marilyn B Renfree

Journal article  |  2008  |  BMC Evolutionary Biology

Expression and protein localisation of IGF2 in the marsupial placenta

Eleanor I Ager, Andrew J Pask, Geoff Shaw, Marilyn B Renfree

Journal article  |  2008  |  BMC Developmental Biology

Insulin is imprinted in the placenta of the marsupial, Macropus eugenii

Eleanor Ager, Shunsuke Suzuki, Andrew Pask, Geoff Shaw, Fumitoshi Ishino, Marilyn B Renfree

Journal article  |  2007  |  Developmental Biology

Recent assembly of an imprinted domain from non-imprinted components.

RW Rapkins, T Hore, M Smithwick, E Ager, AJ Pask, MB Renfree, M Kohn, H Hameister, RD Nicholls, JE Deakin, JAM Graves

Journal article  |  2006  |  PLoS genetics

The rod opsin pigments from two marsupial species, the South American bare-tailed woolly opossum and the Australian fat-tailed dunnart.

David M Hunt, Catherine A Arrese, Miranda von Dornum, Jenny Rodger, Alison Oddy, Jill A Cowing, Eleanor I Ager, James K Bowmaker, Lyn D Beazley, Julia Shand

Journal article  |  2003  |  Gene

Rod visual pigment genes have been studied in a wide range of vertebrates including a number of mammalian species. However, no mar..

Searching by visual and acoustic cues among bushcrickets (Orthoptera: Tettigoniidae): Will females remain faithful to a male who stops calling?

WJ Bailey, EI Ager, EK O'Brien, DL Watson

Journal article  |  2003  |  Physiological Entomology