Stefan Kane

Preimplantation Genetic Testing for Monogenic Conditions: Is Cell-Free DNA Testing the Next Step?

Alice Rogers, Melody Menezes, Stefan C Kane, Deirdre Zander-Fox, Tristan Hardy

Journal article  |  2021  |  MOLECULAR DIAGNOSIS & THERAPY

Genetic assessment of an embryo via preimplantation genetic testing (PGT) represents an important reproductive option for couples ..

Parental Preconception Exposures to Outdoor Neighbourhood Environments and Adverse Birth Outcomes: A Protocol for a Scoping Review and Evidence Map

Suzanne Mavoa, Daniel Keevers, Stefan C Kane, Melissa Wake, Rachel Tham, Kate Lycett, Yen Ting Wong, Katherine Chong

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

Parental preconception exposures to built and natural outdoor environments could influence pregnancy and birth outcomes either dir..

How can obstetricians improve outcomes for infants born extremely preterm?

Stefan C Kane, Katie M Groom, Caroline A Crowther

Journal article  |  2021  |  Semin Perinatol

Prematurity remains a leading cause of perinatal morbidity and mortality, and also has significant implications for long-term heal..

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

Caroline Ovadia, Jenna Sajous, Paul T Seed, Kajol Patel, Nicholas J Williamson, George Attilakos, Francesco Azzaroli, Yannick Bacq, Linoy Batsry, Kelsey Broom, Romana Brun-Furrer, Laura Bull, Jenny Chambers, Yue Cui, Min Ding, Peter H Dixon, Maria C Estiu, Fergus W Gardiner, Victoria Geenes, Monika Grymowicz, et al.

Journal article  |  2021  |  LANCET GASTROENTEROLOGY & HEPATOLOGY

BACKGROUND: Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of pregnancy, yet its largest trial detected m..

Lung ultrasound during newborn resuscitation predicts the need for surfactant therapy in very- and extremely preterm infants

Shiraz Badurdeen, C Omar F Kamlin, Sheryle R Rogerson, Stefan C Kane, Graeme R Polglase, Stuart B Hooper, Peter G Davis, Douglas A Blank

Journal article  |  2021  |  RESUSCITATION

INTRODUCTION: Early identification of infants requiring surfactant therapy improves outcomes. We evaluated the accuracy of deliver..

The addition of fetal scalp blood lactate measurement as an adjunct to cardiotocography to reduce caesarean sections during labour: The Flamingo randomised controlled trial

Christine E East, Mary-Ann Davey, C Omar F Kamlin, Peter G Davis, Penelope M Sheehan, Stefan C Kane, Shaun P Brennecke

Journal article  |  2021  |  AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY

BACKGROUND: Fetal scalp blood sampling for lactate measurement (FBSLM) is sometimes used to assist in identification of the need f..

DAAM2 is elevated in the circulation and placenta in pregnancies complicated by fetal growth restriction and is regulated by hypoxia

Natasha de Alwis, Sally Beard, Natalie K Binder, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Owen Stock, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lisa Hui, Stephen Tong, Natalie J Hannan

Journal article  |  2021  |  SCIENTIFIC REPORTS

Previously, we identified increased maternal circulating DAAM2 mRNA in pregnancies complicated by preterm fetal growth restriction..

Heart Disease and Pregnancy: The Need for a Twenty-First Century Approach to Care ...

William A Parsonage, Dominica Zentner, Karin Lust, Stefan C Kane, Elizabeth A Sullivan

Journal article  |  2021  |  HEART LUNG AND CIRCULATION

Pregnancy and childbirth present a specific challenge to the maternal cardiovascular system. Pre-existing cardiac diseases, or car..

The rhesus incompatible pregnancy and its consequences for affected fetuses and neonates

Caroline Tyndall, Rocco Cuzzilla, Stefan C Kane

Journal article  |  2020  |  TRANSFUSION AND APHERESIS SCIENCE

Rhesus incompatibility in pregnancy may result in haemolytic disease of the fetus and newborn (HDFN). This review discusses the fe..

Prediction of preterm pre-eclampsia at midpregnancy using a multivariable screening algorithm

Carin Black, Daniel Lorber Rolnik, Ahmed Al-Amin, Stefan C Kane, Caroline Stolarek, Adrienne White, Fabricio Da Silva Costa, Shaun Brennecke

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

BACKGROUND: Competing risk models used for midpregnancy prediction of preterm pre-eclampsia have shown detection rates (DR) of 85%..