Stefan is a maternal fetal medicine subspecialist obstetrician based primarily at the Royal Women's Hospital, Melbourne, where he is head of the Fetal Medicine Unit, acting head of the Diabetes Unit, and Program Director for MFM Training. His clinical engagements cover the spectrum of high-risk pregnancy care, and include preterm birth prevention, multiple pregnancy, fetal medicine and maternal medical disorders in pregnancy.
He also performs tertiary-level fetal and gynaecological ultrasound. Stefan's primary research focus is on the maternal neurological effects of pre-eclampsia. His PhD research project aims to evaluate the potential utility of maternal ophthalmic ultrasound in assessing changes in the cerebrovasculature and intracranial pressure of pre-eclamptic women. Other research interests include structural and genetic fetal anomalies, red blood cell alloimmunisation, preterm birth prevention, and early pregnancy prediction of later complications. He has published over 30 peer-reviewed papers on these topics, and has acted as site co-ordinator for a number of international randomised controlled trials. Stefan is actively engaged in teaching at all levels, from medical students to advanced specialist trainees, and holds an honorary position as a Clinical Senior Lecturer in the Department of Obstetrics and Gynaecology. He has a longstanding interest in prevocational medical education, and serves as an accreditation team leader for the intern accreditation authorities in Victoria and Queensland. He also serves on the Council of the Society of Obstetric Medicine of Australia and New Zealand as honorary secretary, and is a member of the steering committee for the Women's and Newborn Health network of the Melbourne Academic Centre for Health. As the Clinical Lead for Preterm Birth with Safer Care Victoria, Stefan also participates in the Australian Preterm Birth Prevention Alliance.
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Cervical length surveillance for predicting spontaneous preterm birth in women with uterin..
Circulating mRNAs are differentially expressed in pregnancies with severe placental insuff..
Prediction of preterm pre-eclampsia at midpregnancy using a multivariable screening algori..
The Utility of the Congenital Pulmonary Airway Malformation-Volume Ratio in the Assessment..
Displaying the 45 most recent scholarly works by Stefan Kane.
Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirth
Natalie J Hannan, Owen Stock, Rebecca Spencer, Clare Whitehead, Anna L David, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lavinia Gordon, Sally Beard, Kantaraja Chindera, Smita Karegodar, Richard Hiscock, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Stephen Tong
Journal article | 2020 | BMC Medicine
BACKGROUND: Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricte..
Prediction of preterm pre-eclampsia at midpregnancy using a multivariable screening algorithm
Carin Black, Daniel Lorber Rolnik, Ahmed Al-Amin, Stefan C Kane, Caroline Stolarek, Adrienne White, Fabricio Da Silva Costa, Shaun Brennecke
Journal article | 2020 | Australian and New Zealand Journal of Obstetrics and Gynaecology
BACKGROUND: Competing risk models used for midpregnancy prediction of preterm pre-eclampsia have shown detection rates (DR) of 85%..
The Utility of the Congenital Pulmonary Airway Malformation-Volume Ratio in the Assessment of Fetal Echogenic Lung Lesions: A Systematic Review
Stefan C Kane, Emanuele Ancona, Karen L Reidy, Ricardo Palma-Dias
Journal article | 2020 | Fetal Diagnosis and Therapy
Although relatively uncommon, the incidence of fetal echogenic lung lesions - a heterogeneous group of anomalies that includes con..
Optic nerve sonography and ophthalmic artery Doppler velocimetry in healthy pregnant women: an Australian cohort study
Stefan C Kane, Alicia T Dennis, Fabricio Da Silva Costa, Louise H Kornman, Thomas J Cade, Shaun P Brennecke
Journal article | 2019 | Journal of Clinical Ultrasound
PURPOSE: Maternal ocular sonography offers a window into cerebrovascular and intracranial pressure changes in pregnancy. This stud..
Midpregnancy testing for soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF): An inter-assay comparison of three automated immunoassay platforms
Carin Black, Ahmed Al-Amin, Daniel Lorber Rolnik, Stefan C Kane, Caroline Stolarek, Adrienne White, Fabricio da Silva Costa, Shaun Brennecke
Journal article | 2019 | Placenta
Antenatal assessment and postnatal outcome of fetal echogenic lung lesions: a decade's experience at a tertiary referral hospital
Stefan C Kane, Fabricio Da Silva Costa, Joseph A Crameri, Karen L Reidy, Helen Kaganov, Ricardo Palma-Dias
Journal article | 2019 | The Journal of Maternal-Fetal & Neonatal Medicine
Misinterpretation of blood group and antibody screen leading to serious errors in RhD immunoglobulin administration: A report on first two years of data from Serious Transfusion Incident Reporting program.
Christine Akers, Helen Savoia, Stefan Kane, Philip Crispin, Anastazia Keegan, Erica Wood, Bridget Glazebrook, Linley Bielby, Amanda K Davis
Journal article | 2019 | Australian and New Zealand Journal of Obstetrics and Gynaecology
The Serious Transfusion Incident Reporting program (STIR) commenced haemovigilance in relation to RhD immunoglobulin (Ig) administ..
Lung ultrasound immediately after birth to describe normal neonatal transition: an observational study
Douglas A Blank, C Omar Farouk Kamlin, Sheryle R Rogerson, Lisa M Fox, Laila Lorenz, Stefan Charles Kane, Graeme R Polglase, Stuart B Hooper, Peter G Davis
Journal article | 2018 | Archives of Disease in Childhood - Fetal and Neonatal Edition
Severe placental insufficiency, acidemia and imminent stillbirth are associated with changes in circulating levels of mRNA coding NR4A2, RCBTB2 and EMP1
Stephen Tong, Clare Whitehead, Susan Walker, Gordon Lavinia, Jo Said, Katie Groom, Scott Petersen, Sean Seeho, Amanda Henry, Stefan Kane, Natalie Hannan, Owen Stock
Conference Proceedings | 2018 | AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Outcomes and predictive tests from a dedicated specialist clinic for women at high risk of preterm labour: A ten year audit
Kelly Hughes, Shirlene Sim, Alina Roman, Kasia Michalak, Stefan Kane, Penelope Sheehan
Journal article | 2017 | Australian and New Zealand Journal of Obstetrics and Gynaecology
Lung ultrasound during the initiation of breathing in healthy term and late preterm infants immediately after birth, a prospective, observational study
Douglas A Blank, Sheryle R Rogerson, C Omar F Kamlin, Lisa M Fox, Laila Lorenz, Stefan C Kane, Graeme R Polglase, Stuart B Hooper, Peter G Davis
Journal article | 2017 | Resuscitation
Chorionic villus sampling in the cell-free DNA aneuploidy screening era: careful selection criteria can maximise the clinical utility of screening and invasive testing
Stefan C Kane, Karen L Reidy, Fiona Norris, Deborah L Nisbet, Louise H Kornman, Ricardo Palma-Dias
Journal article | 2017 | Prenatal Diagnosis
Enoxaparin for the prevention of preeclampsia and intrauterine growth restriction in women with a history: a randomized trial
Katie M Groom, Lesley M McCowan, Laura K Mackay, Arier C Lee, Joanne M Said, Stefan C Kane, Susan P Walker, Thijs E van Mens, Natalie J Hannan, Stephen Tong, Larry W Chamley, Peter R Stone, Claire McLintock
Journal article | 2017 | American Journal of Obstetrics and Gynecology
Enoxaparin for the prevention of preeclampsia and intrauterine growth restriction in women with a prior history (the eppi trial): an open-label international multicentre randomized controlled trial
Katie Groom, Lesley McCowan, Laura MacKay, Joanne Said, Stefan Kane, Susan Walker, Saskia Middeldorp, Peter Stone, Claire McLintock
Conference Proceedings | 2017 | AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Renal Interlobar Vein Impedance Index as a First-Trimester Marker Does Not Predict Hypertensive Disorders of Pregnancy
Sammya Bezerra Maia e Holanda Moura, Paulo Cesar Praciano, Julio Augusto Gurgel Alves, Wellington P Martins, Edward Araujo Junior, Stefan C Kane, Fabricio da Silva Costa
Journal article | 2016 | Journal of Ultrasound in Medicine
Protocol for a randomised controlled trial of fetal scalp blood lactate measurement to reduce caesarean sections during labour: the Flamingo trial [ACTRN12611000172909]
Christine E East, Stefan C Kane, Mary-Ann Davey, C Omar Kamlin, Shaun P Brennecke
Journal article | 2015 | BMC PREGNANCY AND CHILDBIRTH
Reference values of maternal ophthalmic artery doppler variables in the first trimester of normal pregnancy
Julio Augusto Gurgel Alves, Bruna Yang, Paulo Cesar Praciano de Sousa, Sammya Bezerra Maia e Holanda Moura, Stefan Kane, Fabricio da Silva Costa
Journal article | 2014 | Journal of Clinical Ultrasound
Contemporary clinical management of the cerebral complications of preeclampsia.
Stefan C Kane, Alicia Dennis, Fabricio da Silva Costa, Louise Kornman, Shaun Brennecke
Journal article | 2013 | Obstet Gynecol Int
The neurological complications of preeclampsia and eclampsia are responsible for a major proportion of the morbidity and mortality..
Honours, Awards and Fellowships
RANZCOG Fellows' Clinical Research Scholarship
FRANZCOG - Fellow of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Obstetrics And Gynaecology Royal Women'S Hospital/Mercy
Australian Preterm Birth Prevention Alliance
Society of Obstetric Medicine of Australia and New Zealand
Perinatal Society of Australia and New Zealand
Certification in Maternal Fetal Medicine
Royal Australian and New Zealand College of Obstetricians and Gynaecologists
Diploma of Diagnostic Ultrasound (O&G)
Australasian Society for Ultrasound in Medicine
Bachelor of Medicine / Bachelor of Surgery
University of Melbourne
Bachelor of Medical Science
University of Melbourne
Bachelor of Arts
University of Melbourne