Paul Mitchell

Optimal care pathways: A national policy to improve quality of cancer care and address inequalities in cancer outcomes

Rebecca J Bergin, Kathryn Whitfield, Victoria White, Roger L Milne, Jon D Emery, Anna Boltong, David Hill, Paul Mitchell, David Roder, Euan Walpole, Luc te Marvelde, Robert JS Thomas

Journal article  |  2020  |  Journal of Cancer Policy

Genome-wide meta-analysis identifies novel loci associated with age-related macular degeneration

Xikun Han, Puya Gharahkhani, Paul Mitchell, Gerald Liew, Alex W Hewitt, Stuart MacGregor

Journal article  |  2020  |  Journal of Human Genetics

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness among the elderly population. To accelerate ..

NTRK and ALK rearrangements in malignant pleural mesothelioma, pulmonary neuroendocrine tumours and non-small cell lung cancer

Jose Luis Leal, Geoffrey Peters, Marcin Szaumkessel, Trishe Leong, Khashayar Asadi, Gareth Rivalland, Hongdo Do, Clare Senko, Paul L Mitchell, Chai Zi Quing, Alexander Dobrovic, Bibhusal Thapa, Thomas John

Journal article  |  2020  |  Lung Cancer

OBJECTIVES: Gene rearrangements involving NTRK1, NTRK2, NTRK3, ROS1 and ALK have been identified in many types of cancer, includin..

Impact of Radiotherapy on the Efficacy and Toxicity of anti-PD-1 Inhibitors in Metastatic NSCLC.

Evangeline Samuel, Gabrielle Lie, Adithya Balasubramanian, Alison Hiong, Yeojeong So, Mark Voskoboynik, Maggie Moore, Mark Shackleton, Andrew Haydon, Tom John, Paul LR Mitchell, Ben Markman, Peter Briggs, Sagun Parakh

Journal article  |  2020  |  Clinical Lung Cancer

BACKGROUND: The impact of radiotherapy (RT) on the efficacy and toxicity of immune checkpoint inhibitors (ICIs) in patients with m..

Reply to the letter-to-the editor "Hospital volume and the case for centralisation of surgical services".

AA Thai, E Stuart, L Te Marvelde, RL Milne, S Knight, K Whitfield, P Mitchell

Journal article  |  2020  |  Lung Cancer

Credentialing of vertebral stereotactic ablative body radiotherapy in a multi-centre trial

Nicholas Hardcastle, Tomas Kron, Olivia Cook, Joerg Lehmann, Paul LR Mitchell, Shankar Siva

Journal article  |  2020  |  Physica Medica

PURPOSE/OBJECTIVE: Stereotactic ablative body radiotherapy (SABR) in multi-centre trials requires rigorous quality assurance to en..

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Qiao Fan, Alfred Pozarickij, Nicholas YQ Tan, Xiaobo Guo, Virginie JM Verhoeven, Veronique Vitart, Jeremy A Guggenheim, Masahiro Miyake, J Willem L Tideman, Anthony P Khawaja, Liang Zhang, Stuart MacGregor, Rene Hoehn, Peng Chen, Ginevra Biino, Juho Wedenoja, Seyed Ehsan Saffari, Milly S Tedja, Jing Xie, Carla Lanca, et al.

Journal article  |  2020  |  Communications Biology

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and b..

Occult Gastrointestinal Perforation in a Patient With EGFR-Mutant Non-Small-Cell Lung Cancer Receiving Combination Chemotherapy With Atezolizumab and Bevacizumab: Brief Report

Ashray Gunjur, Geoff Chong, Adeline Lim, Eddie Lau, Paul Mitchell, Thomas John, Surein Arulananda

Journal article  |  2020  |  Clinical Lung Cancer

Association of Genetic Variation With Keratoconus

Bennet J McComish, Srujana Sahebjada, Yelena Bykhovskaya, Colin E Willoughby, Andrea J Richardson, Abi Tenen, Jac C Charlesworth, Stuart MacGregor, Paul Mitchell, Sionne EM Lucas, Richard A Mills, David A Mackey, Xiaohui Li, Jie Jin Wang, Richard A Jensen, Jerome I Rotter, Kent D Taylor, Alex W Hewitt, Yaron S Rabinowitz, Paul N Baird, et al.

Journal article  |  2020  |  JAMA Ophthalmology

Importance: Keratoconus is a condition in which the cornea progressively thins and protrudes in a conical shape, severely affectin..

A Malignant Neoplasm From the Jejunum With a MALAT1-GLI1 Fusion and 26-Year Survival History

Owen William John Prall, Christopher Robert Edward McEvoy, David John Byrne, Amir Iravani, Judy Browning, David Yew-Huong Choong, Bhargavi Yellapu, Sophie O'Haire, Kortnye Smith, Stephen James Luen, Paul Leslie Ross Mitchell, Jayesh Desai, Stephen Bernard Fox, Andrew Fellowes, Huiling Xu

Journal article  |  2020  |  International Journal of Surgical Pathology

The transcription factor GLI1 is a critical effector of the sonic hedgehog pathway. Gene fusions that activate GLI1 have recently ..