Prof Tien Wong

Find out more about Tien Wong's experience

Tien Wong's highlights

FEATURED Journal article

Computerized adaptive tests: Efficient and precise assessment of the patient-centered impact of diabetic retinopathy

Tien Wong's selected work

Cra - Retinal Vascular Research

Research Contracts

Association of alcohol intake with incidence and progression of diabetic retinopathy.

Research Grant

Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and ..

Journal article

Novel Predictors Of Retinal Vascular Calibre In Diabetes

Research Grant

Cardiovascular health and retinal microvascular geometry in Australian 11-12 year-olds

Projects

Displaying the 5 most recent projects by Tien Wong.

Cra - Retinal Vascular Research

2011 - 2015

Completed

NHMRC Research Fellowship

My research programme seeks to develop retinal vascular imaging as a novel technique for prediction of cardiovascular disease.

2008 - 2011

Completed

Asia Pacific Grading Workshop 2008

Retinal Microvascular Signs And Cvd In Older Persons

Early Retinal Vessel Changes In Diabetes And The Metabolic Syndrome

Diabetes mellitus affects a large proportion of adult Australians. Furthermore, many non-diabetic Australians are at high risk of developing..

5

Projects

Project Types

Research Grant

Internal Research Grant

Research Contracts

Scholarly Works

Displaying the 962 most recent scholarly works by Tien Wong.

Computerized adaptive tests: Efficient and precise assessment of the patient-centered impact of diabetic retinopathy

EK Fenwick, J Barnard, A Gan, BS Loe, J Khadka, K Pesudovs, R Man, SY Lee, G Tan, TY Wong, EL Lamoureux

Journal article | 2020 | Translational Vision Science & Technology

Association of alcohol intake with incidence and progression of diabetic retinopathy.

Preeti Gupta, Eva K Fenwick, Charumathi Sabanayagam, Alfred Tau Liang Gan, Yih-Chung Tham, Sahil Thakur, Ryan Eyn Kidd Man, Paul Mitchell, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article | 2020 | British Journal of Ophthalmology

PURPOSE: We examined the longitudinal association of baseline alcohol intake and frequency with the 6-year incidence and progressi..

Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections

Ching-Yu Cheng, Ningli Wang, Tien Y Wong, Nathan Congdon, Mingguang He, Ya Xing Wang, Tasanee Braithwaite, Robert J Casson, Maria Vittoria Cicinelli, Aditi Das, Seth R Flaxman, Jost B Jonas, Jill Elizabeth Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Serge Resnikoff, Alexander J Silvester, et al.

Journal article | 2020 | British Journal of Ophthalmology

BACKGROUND: To determine the prevalence and causes of blindness and vision impairment (VI) in East Asia in 2015 and to forecast th..

Cardiovascular health and retinal microvascular geometry in Australian 11-12 year-olds

Mengjiao Liu, Kate Lycett, Melissa Wake, Mingguang He, Jessica A Kerr, Richard Saffery, Markus Juonala, Tim Olds, Terry Dwyer, David P Burgner, Tien Yin Wong

Journal article | 2020 | Microvascular Research

Traditional retinal microvascular parameters (smaller arteriolar and greater venular caliber) are associated with cardiovascular r..

Associations of Retinal Vessel Caliber With Hearing Status in Childhood and Midlife A Cross-Generational Population-Based Study

Jing Wang, Mengjiao Liu, Valerie Sung, Kate Lycett, Anneke Grobler, David Burgner, Tien Yin Wong, Melissa Wake

Journal article | 2020 | JAMA Otolaryngology–Head & Neck Surgery

Importance: Microvascular phenotypes, which can be assessed using retinal imaging, may be informative about the life course pathog..

Inflammation mediates the relationship between obesity and retinal vascular calibre in 11-12 year-olds children and mid-life adults.

Mengjiao Liu, Kate Lycett, Margarita Moreno-Betancur, Tien Yin Wong, Mingguang He, Richard Saffery, Markus Juonala, Jessica A Kerr, Melissa Wake, David P Burgner

Journal article | 2020 | Scientific Reports

Obesity predicts adverse microvasculature from childhood, potentially via inflammatory pathways. We investigated whether inflammat..

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Qiao Fan, Alfred Pozarickij, Nicholas YQ Tan, Xiaobo Guo, Virginie JM Verhoeven, Veronique Vitart, Jeremy A Guggenheim, Masahiro Miyake, J Willem L Tideman, Anthony P Khawaja, Liang Zhang, Stuart MacGregor, Rene Hoehn, Peng Chen, Ginevra Biino, Juho Wedenoja, Seyed Ehsan Saffari, Milly S Tedja, Jing Xie, Carla Lanca, et al.

Journal article | 2020 | Communications Biology

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and b..

Validation of a novel diabetic retinopathy utility index using discrete choice experiments

Eva K Fenwick, Nick Bansback, Alfred Tau Liang Gan, Julie Ratcliffe, Leonie Burgess, Tien Yin Wong, Ecosse Luc Lamoureux

Journal article | 2020 | British Journal of Ophthalmology

BACKGROUND/AIMS: To validate a preference-based Diabetic Retinopathy Utility Index (DRU-I) using discrete choice experiment (DCE) ..

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

Pieter WM Bonnemaijer, Elisabeth M van Leeuwen, Adriana I Iglesias, Puya Gharahkhani, Veronique Vitart, Anthony P Khawaja, Mark Simcoe, Rene Hoehn, Angela J Cree, Rob P Igo, Kathryn P Burdon, Jamie E Craig, Alex W Hewitt, Jost Jonas, Chiea-Cheun Khor, Francesca Pasutto, David A Mackey, Paul Mitchell, Aniket Mishra, Calvin Pang, et al.

Journal article | 2019 | Communications Biology

Genetic architecture of subcortical brain structures in 38,851 individuals

Claudia L Satizabal, Hieab HH Adams, Derrek P Hibar, Charles C White, Maria J Knol, Jason L Stein, Markus Scholz, Muralidharan Sargurupremraj, Neda Jahanshad, Gennady Roshchupkin, Albert Smith, Joshua C Bis, Xueqiu Jian, Michelle Luciano, Edith Hofer, Alexander Teumer, Sven J van der Lee, Jingyun Yang, Lisa R Yanek, Tom Lee, et al.

Journal article | 2019 | Nature Genetics

Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation ..

Natural history of diabetic macular edema and factors predicting outcomes in sham-treated patients (MEAD study)

Young Hee Yoon, David S Boyer, Raj K Maturi, Francesco Bandello, Rubens Belfort, Albert J Augustin, Xiao-Yan Li, Zhanying Bai, Yehia Hashad, Suel Abujamra, James Acton, Fareed Ali, Andrew Antoszyk, Albert J Augustin, Carl C Awh, Adiel Barak, Karl Ulrich Bartz-Schmidt, Caroline R Baumal, Rubens Belfort, Muna Bhende, et al.

Journal article | 2019 | Graefe's Archive for Clinical and Experimental Ophthalmology

Associations of retinal microvascular caliber with intermediate phenotypes of large arterial function and structure: A systematic review and meta-analysis

Mengjiao Liu, Melissa Wake, Tien Yin Wong, Mingguang He, Yinzong Xiao, David P Burgner, Kate Lycett

Journal article | 2019 | Microcirculation

OBJECTIVE: Intermediate phenotypes of microcirculation (retinal microvascular caliber) are associated with cardiovascular (CV) ris..

Health-related behaviours in a remote Indigenous population with Type 2 diabetes: a Central Australian primary care survey in the Telehealth Eye and Associated Medical Services Network [TEAMSnet] project

D Xu, A Jenkins, C Ryan, A Keech, A Brown, J Boffa, K O'Dea, SE Bursell, L Brazionis, David O'Neal, Danny Liew, Tien Wong, Hugh Taylor, Anthony Keech, Ecosse Lamoureux, Mark Horton, Laima Brazionis, Christopher Ryan, Justin Tse

Journal article | 2019 | Diabetic Medicine

Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population.

Eva K Fenwick, Ryan EK Man, Alfred Tau Liang Gan, Neelam Kumari, Charlene Wong, Amudha Aravindhan, Preeti Gupta, Jie Jin Wang, Paul Mitchell, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article | 2019 | British Journal of Ophthalmology

BACKGROUND/AIMS: To assess the independent impact of diabetic retinopathy (DR) on three domains of vision-related quality of life ..

Child Health CheckPoint: cohort summary and methodology of a physical health and biospecimen module for the Longitudinal Study of Australian Children

Susan A Clifford, Sarah Davies, Melissa Wake, Peter S Azzopardi, Louise A Baur, David P Burgner, John B Carlin, Michael Cheung, Terence Dwyer, Ben Edwards, Susan Ellul, Alanna N Gillespie, Lisa Gold, Anneke C Grobler, Jessica A Kerr, Kate Lycett, Katherine Lange, Fiona K Mensah, Timothy S Olds, Sarath Ranganathan, et al.

Journal article | 2019 | BMJ Open

OBJECTIVES: 'Growing Up in Australia: The Longitudinal Study of Australian Children' (LSAC) is Australia's only nationally represe..

Retinal microvasculature: population epidemiology and concordance in Australian children aged 11-12 years and their parents

Julian Dascalu, Mengjiao Liu, Kate Lycett, Anneke C Grobler, Mingguang He, David P Burgner, Tien Yin Wong, Melissa Wake

Journal article | 2019 | BMJ Open

OBJECTIVES: To describe distributions and concordance of retinal microvasculature measurements in a population-based sample of Aus..

Prevalence and causes of blindness and vision impairment: magnitude, temporal trends and projections in South and Central Asia

Vinay Nangia, Jost B Jonas, Ronnie George, Vijaya Lingam, Leon Ellwein, Maria Vittoria Cicinelli, Aditi Das, Seth R Flaxman, Jill E Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Serge Resnikoff, Alexander J Silvester, Nina Tahhan, Hugh R Taylor, Tien Y Wong, Rupert RA Bourne

Journal article | 2019 | British Journal of Ophthalmology

Prevalence and causes of vision loss in Latin America and the Caribbean in 2015: magnitude, temporal trends and projections

Janet L Leasher, Tasanee Braithwaite, Joao M Furtado, Seth R Flaxman, Van Charles Lansingh, Juan Carlos Silva, Serge Resnikoff, Hugh R Taylor, Rupert RA Bourne, Rupert Bourne, Peter Ackland, Aries Arditi, Yaniv Barkana, Banu Bozkurt, Alain Bron, Donald Budenz, Feng Cai, Robert Casson, Usha Chakravarthy, Jaewan Choi, et al.

Journal article | 2019 | British Journal of Ophthalmology

A Multi-Country Study of Myopia in Children: Digital Data Capture Using an Innovative Application - plano

Mohamed Dirani, Arief Salim, Stuart Keel, Jonathan G Crowston, Tien Yin Wong

Conference Proceedings | 2019 | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Prevalence and causes of vision loss in South-east Asia and Oceania in 2015: magnitude, temporal trends and projections

Jill Elizabeth Keeffe, Robert J Casson, Konrad Pesudovs, Hugh R Taylor, Maria Vittoria Cicinelli, Aditi Das, Seth R Flaxman, Jost B Jonas, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Alexander J Silvester, Gretchen A Stevens, Nina Tahhan, Tien Yin Wong, Serge Resnikoff, Rupert RA Bourne

Journal article | 2019 | British Journal of Ophthalmology

Prevalence and causes of vision loss in North Africa and Middle East in 2015: magnitude, temporal trends and projections

Rim Kahloun, Moncef Khairallah, Serge Resnikoff, Maria Vittoria Cicinelli, Seth R Flaxman, Aditi Das, Jost B Jonas, Jill E Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Alexander J Silvester, Nina Tahhan, Hugh R Taylor, Tien Yin Wong, Rupert RA Bourne

Journal article | 2019 | British Journal of Ophthalmology

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Honor Bixby, James Bentham, Bin Zhou, Mariachiara Di Cesare, Christopher J Paciorek, James E Bennett, Cristina Taddei, Gretchen A Stevens, Andrea Rodriguez-Martinez, Rodrigo M Carrillo-Larco, Young-Ho Khang, Maroje Soric, Edward W Gregg, J Jaime Miranda, Zulfiqar A Bhutta, Stefan Savin, Marisa K Sophiea, Maria LC Iurilli, Bethlehem D Solomon, Melanie J Cowan, et al.

Journal article | 2019 | Nature

Microvascular narrowing and BP monitoring: A single centre observational study

Fariya Ali, Mark Tacey, Nick Lykopandis, Deb Colville, Ecosse Lamoureux, Tien Y Wong, William Vangaal, Anastasia Hutchinson, Judy Savige

Journal article | 2019 | PLOS ONE

Myopia - A 21st Century Public Health Issue

Serge Resnikoff, Jost B Jonas, David Friedman, Mingguage He, Monica Jong, Jason J Nichols, Kyoko Ohno-Matsui, Earl L Smith, Christine F Wildsoet, Hugh R Taylor, James S Wolffsohn, Tien Y Wong

Journal article | 2019 | Investigative Opthalmology & Visual Science

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Ganesh Chauhan, Hieab HH Adams, Claudia L Satizabal, Joshua C Bis, Alexander Teumer, Muralidharan Sargurupremraj, Edith Hofer, Stella Trompet, Saima Hilal, Albert Vernon Smith, Xueqiu Jian, Rainer Malik, Matthew Traylor, Sara L Pulit, Philippe Amouyel, Bernard Mazoyer, Yi-Cheng Zhu, Sara Kaffashian, Sabrina Schilling, Gary W Beecham, et al.

Journal article | 2019 | Neurology

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (vol 9, 1864, 2018)

Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, Rene Hoehn, Henriet Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N Cooke Bailey, Colin E Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P Khawaja, Ozren Polasek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L Haines, Lisa S Kearns, et al.

Journal article | 2019 | Nature Communications

From reading books to increased smart device screen time

Mohamed Dirani, Jonathan G Crowston, Tien Y Wong

Journal article | 2019 | British Journal of Ophthalmology

Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders

Yasmin Bylstra, Jyn Ling Kuan, Weng Khong Lim, Jaydutt Digambar Bhalshankar, Jing Xian Teo, Sonia Davila, Bin Tean Teh, Steve Rozen, Ene-Choo Tan, Wendy Kein Meng Liew, Khung Keong Yeo, Patrick Tan, Vikrant Kumar, Christropher Blocker, Ryanne Wu, Angeline Lai, Ee Shien Tan, Ivy Ng, Breana Cham, Jiin Ying Lim, et al.

Journal article | 2019 | Genetics in Medicine

An Automated Grading System for Detection of Vision-Threatening Referable Diabetic Retinopathy on the Basis of Color Fundus Photographs

Zhixi Li, Stuart Keel, Chi Liu, Yifan He, Wei Meng, Jane Scheetz, Pei Ying Lee, Jonathan Shaw, Daniel Ting, Tien Yin Wong, Hugh Taylor, Robert Chang, Mingguang He

Journal article | 2018 | Diabetes Care

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017

Jeffrey D Stanaway, Ashkan Afshin, Emmanuela Gakidou, Stephen S Lim, Degu Abate, Kalkidan Hassell Abate, Cristiana Abbafati, Nooshin Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Ibrahim Abdollahpour, Rizwan Suliankatchi Abdulkader, Molla Abebe, Zegeye Abebe, Semaw F Abera, Olifan Zewdie Abil, Haftom Niguse Abraha, Aklilu Roba Abrham, et al.

Journal article | 2018 | LANCET

The Relationship between Generalized and Abdominal Obesity with Diabetic Kidney Disease in Type 2 Diabetes: A Multiethnic Asian Study and Meta-Analysis

Ryan Eyn Kidd Man, Alfred Tau Liang Gan, Eva Katie Fenwick, Preeti Gupta, Mark Yu Zheng Wong, Tien Yin Wong, Gavin Siew Wei Tan, Boon Wee Teo, Charumathi Sabanayagam, Ecosse Luc Lamoureux

Journal article | 2018 | Nutrients

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes

Weihua Meng, Kaanan P Shah, Samuela Pollack, Iiro Toppila, Harry L Hebert, Mark I McCarthy, Leif Groop, Emma Ahlqvist, Valeriya Lyssenko, Elisabet Agardh, Mark Daniell, Georgia Kaidonis, Jamie E Craig, Paul Mitchell, Gerald Liew, Annette Kifley, Jie Jin Wang, Mark W Christiansen, Richard A Jensen, Alan Penman, et al.

Journal article | 2018 | Acta Ophthalmologica

Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study

Matthew D Campbell, Tomi T Laitinen, Alun Hughes, Katja Pahkala, Markus Juonala, Mika Kahonen, Tien Y Wong, Terho Lehtimaki, Nina Hutri-Kahonen, Olli T Raitakari, Robyn J Tapp

Journal article | 2018 | Journal of the American Heart Association

Guidelines on Diabetic Eye Care The International Council of Ophthalmology Recommendations for Screening, Follow-up, Referral, and Treatment Based on Resource Settings

Tien Y Wong, Jennifer Sun, Ryo Kawasaki, Paisan Ruamviboonsuk, Neeru Gupta, Van Charles Lansingh, Mauricio Maia, Wanjiku Mathenge, Sunil Moreker, Mahi MK Muqit, Serge Resnikoff, Juan Verdaguer, Peiquan Zhao, Frederick Ferris, Lloyd P Aiello, Hugh R Taylor

Journal article | 2018 | Ophthalmology

Age-related macular degeneration

Paul Mitchell, Gerald Liew, Bamini Gopinath, Tien Y Wong

Journal article | 2018 | The Lancet

Association of serum lutein and zeaxanthin with quantitative measures of retinal vascular parameters

Neelam Kumari, Joanna Cher, Edwin Chua, Haslina Hamzah, Tien Yin Wong, Carol Y Cheung

Journal article | 2018 | PLOS ONE

Diet soft drink is associated with increased odds of proliferative diabetic retinopathy

Eva K Fenwick, Alfred TL Gan, Ryan EK Man, Charumathi Sabanayagam, Preeti Gupta, Krystal Khoo, Amudha Aravindhan, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2018 | Clinical & Experimental Ophthalmology

Impact of Incidence and Progression of Diabetic Retinopathy on Vision-Specific Functioning

Preeti Gupta, Alfred Tau Liang Gan, Ryan Eyn Kidd Man, Eva K Fenwick, Neelam Kumari, Gavin Tan, Paul Mitchell, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse L Lamoureux

Journal article | 2018 | Ophthalmology

A novel model of persistent retinal neovascularization for the development of sustained anti-VEGF therapies

Yong Li, Joanna Marie Busoy, Ben Alfyan Achirn Zaman, Queenie Shu Woon Tan, Gavin Siew Wei Tan, Veluchamy Amutha Barathi, Ning Cheung, Jay Ji-Ye Wei, Walter Hunziker, Wanjin Hong, Tien Yin Wong, Chui Ming Gemmy Cheung

Journal article | 2018 | Experimental Eye Research

Macro- and Microvascular Parameters After Toxic Shock Syndrome

Katherine YH Chen, Ling-Jun Li, Tien Y Wong, Carol Y Cheung, Nigel Curtis, Michael Cheung, David P Burgner

Journal article | 2018 | The Pediatric Infectious Disease Journal

Reply.

Mark Yu Zheng Wong, Ryan Eyn Kidd Man, Preeti Gupta, Charumathi Sabanayagam, Sing Hui Lim, Blanche Lim, Yih-Chung Tham, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article | 2018 | American Journal of Ophthalmology

Retinal Arteriolar Narrowing in Young Adults With Glaucomatous Optic Disc

Rossada Adiarti, Retno Ekantini, Angela N Agni, Tien Y Wong, Muhammad B Sasongko

Journal article | 2018 | Journal of Glaucoma

Age-related macular degeneration and progression of coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis

Antonio B Fernandez, Kevin D Ballard, Tien Y Wong, Mengye Guo, Robyn L McClelland, Gregory Burke, Mary Frances Cotch, Barbara Klein, Matthew Allison, Ronald Klein

Journal article | 2018 | PLOS ONE

Inter-relationship between visual symptoms, activity limitation and psychological functioning in patients with diabetic retinopathy

Eva K Fenwick, Grand H-L Cheng, Ryan EK Man, Jyoti Khadka, Gwyn Rees, Tien Y Wong, Konrad Pesudovs, Ecosse Luc Lamoureux

Journal article | 2018 | British Journal of Ophthalmology

Global prevalence of visual impairment associated with myopic macular degeneration and temporal trends from 2000 through 2050: systematic review, meta-analysis and modelling

Timothy R Fricke, Monica Jong, Kovin S Naidoo, Padmaja Sankaridurg, Thomas J Naduvilath, Suit May Ho, Tien Yin Wong, Serge Resnikoff

Journal article | 2018 | British Journal of Ophthalmology

CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy

Yoshikatsu Hosoda, Munemitsu Yoshikawa, Masahiro Miyake, Yasuharu Tabara, Jeeyun Ahn, Se Joon Woo, Shigeru Honda, Yoichi Sakurada, Chieko Shiragami, Hideo Nakanishi, Akio Oishi, Sotaro Ooto, Akiko Miki, Tomohiro Iida, Hiroyuki Iijima, Makoto Nakamura, Chiea Chuen Khor, Tien Yin Wong, Kyuyoung Song, Kyu Hyung Park, et al.

Journal article | 2018 | Proceedings of the National Academy of Sciences

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Milly S Tedja, Robert Wojciechowski, Pirro G Hysi, Nicholas Eriksson, Nicholas A Furlotte, Virginie JM Verhoeven, Adriana I Iglesias, Magda A Meester-Smoor, Stuart W Tompson, Qiao Fan, Anthony P Khawaja, Ching-Yu Cheng, Rene Hoehn, Kenji Yamashiro, Adam Wenocur, Clare Grazal, Toomas Haller, Andres Metspalu, Juho Wedenoja, Jost B Jonas, et al.

Journal article | 2018 | Nature Genetics

Associations between sleep duration, sleep quality and diabetic retinopathy

Nicholas YQ Tan, Merwyn Chew, Yih-Chung Tham, Duc Nguyen Quang, Masayuki Yasuda, Ching-Yu Cheng, Tien Yin Wong, Charumathi Sabanayagam

Journal article | 2018 | PLOS ONE

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Journal article | 2018 | Nature Communications

Are light masks useful for early diabetic macular oedema?

Tien Yin Wong

Journal article | 2018 | The Lancet Diabetes & Endocrinology

Choroidal Nevi in the Singapore Epidemiology of Eye Disease Study

Si Rui Ng, Wanting Zhao, Paul Mitchell, Jie Jin Wang, Hui Xian Valencia Foo, Kumari Neelam, Ching-Yu Cheng, Tien Yin Wong, Ning Cheung

Journal article | 2018 | Ophthalmology

Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe in 2015: magnitude, temporal trends and projections

Rupert RA Bourne, Jost B Jonas, Alain M Bron, Maria Vittoria Cicinelli, Aditi Das, Seth R Flaxman, David S Friedman, Jill E Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Tunde Peto, Jinan Saadine, Alexander J Silvester, Nina Tahhan, Hugh R Taylor, Rohit Varma, Tien Y Wong, et al.

Journal article | 2018 | British Journal of Ophthalmology

Al for medical imaging goes deep

Daniel SW Ting, Yong Liu, Philippe Burlina, Xinxing Xu, Neil M Bressler, Tien Y Wong

Journal article | 2018 | Nature Medicine

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus.

Bao Jian Fan, Xueli Chen, Nisha Sondhi, P Ferdinamarie Sharmila, Nagasamy Soumittra, Sarangapani Sripriya, Srinivasan Sacikala, Rashima Asokan, David S Friedman, Louis R Pasquale, X Raymond Gao, Lingam Vijaya, Jessica Cooke Bailey, Veronique Vitart, Stuart MacGregor, Christopher J Hammond, Chiea Chuen Khor, Jonathan L Haines, Ronnie George, Janey L Wiggs, et al.

Journal article | 2018 | Investigative Opthalmology & Visual Science

Purpose: To identify genetic risk factors contributing to central corneal thickness (CCT) in individuals from South India, a popul..

Individuals' Perspectives on Coping with Vision Loss from Diabetic Retinopathy

Bonnie A Sturrock, Gwyneth Rees, Ecosse L Lamoureux, Tien Y Wong, Edith Holloway, Eva K Fenwick

Journal article | 2018 | Optometry and Vision Science

Changes in retinal venular oxygen saturation predict activity of proliferative diabetic retinopathy 3 months after panretinal photocoagulation

Thomas Lee Torp, Ryo Kawasaki, Tien Yin Wong, Tunde Peto, Jakob Grauslund

Journal article | 2018 | British Journal of Ophthalmology

Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration

Eva K Fenwick, Gemmy Chui Ming Cheung, Alfred TL Gan, Gavin Tan, Shu Yen Lee, Doric Wong, Ian Yeo, Ranjana Mathur, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2018 | British Journal of Ophthalmology

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

Yun J Sung, Thomas W Winkler, Lisa de las Fuentes, Amy R Bentley, Michael R Brown, Aldi T Kraja, Karen Schwander, Ioanna Ntalla, Xiuqing Guo, Nora Franceschini, Yingchang Lu, Ching-Yu Cheng, Xueling Sim, Dina Vojinovic, Jonathan Marten, Solomon K Musani, Changwei Li, Mary F Feitosa, Tuomas O Kilpelainen, Melissa A Richard, et al.

Journal article | 2018 | The American Journal of Human Genetics

The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy

Shyam S Chaurasia, Rayne R Lim, Bhav H Parikh, Yeo Sia Wey, Bo Bo Tun, Tien Yin Wong, Chi D Luu, Rupesh Agrawal, Arkasubhra Ghosh, Alessandra Mortellaro, Elizabeth Rackoczy, Rajiv R Mohan, Veluchamy A Barathi

Journal article | 2018 | SCIENTIFIC REPORTS

A genome-wide association study of corneal astigmatism: The CREAM Consortium

Rupal L Shah, Qing Li, Wanting Zhao, Milly S Tedja, J Willem L Tideman, Anthony P Khawaja, Qiao Fan, Seyhan Yazar, Katie M Williams, Virginie JM Verhoeven, Jing Xie, Ya Xing Wang, Moritz Hess, Stefan Nickels, Karl J Lackner, Olavi Parssinen, Juho Wedenoja, Ginevra Biino, Maria Pina Concas, Andre Uitterlinden, et al.

Journal article | 2018 | Molecular Vision

Comparison of retinal vascular geometry in obese and non-obese children

Evelyn Li Min Tai, Yee Cheng Kueh, Wan-Hazabbah Wan Hitam, Tien Yin Wong, Ismail Shatriah

Journal article | 2018 | PLOS ONE

Prevalence, subtypes, severity and determinants of ocular trauma: The Singapore Chinese Eye Study

Mark YZ Wong, Ryan EK Man, Preeti Gupta, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article | 2018 | British Journal of Ophthalmology

A spectrum of retinal vasculature measures and coronary artery disease

Sarah B Wang, Paul Mitchell, Gerald Liew, Tien Yin Wong, Kevin Phan, Aravinda Thiagalingam, Nichole Joachim, George Burlutsky, Bamini Gopinath

Journal article | 2018 | Atherosclerosis

Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study

Robyn J Tapp, Alun D Hughes, Mika Kahonen, Tien Yin Wong, Nicholas Witt, Terho Lehtimaki, Nina Hutri-Kahonen, Pinki Sahota, Markus Juonala, Olli T Raitakari

Journal article | 2018 | Journal of the American Heart Association

The Study of Neurocognitive Outcomes, Radiological and Retinal Effects of Aspirin in Sleep Apnoea- rationale and methodology of the SNORE-ASA study

Stephanie Alison Ward, Elsdon Storey, Robyn L Woods, Garun S Hamilton, Ryo Kawasaki, Andrew L Janke, Matthew T Naughton, Fergal O'Donoghue, Rory Wolfe, Tien Y Wong, Christopher M Reid, Walter P Abhayaratna, Nigel Stocks, Ruth Trevaks, Sharyn Fitzgerald, Lauren AB Hodgson, Liubov Robman, Barbara Workman, John J McNeil

Journal article | 2018 | Contemporary Clinical Trials

Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes

Daniel Shu Wei Ting, Carol Yim-Lui Cheung, Gilbert Lim, Gavin Siew Wei Tan, Nguyen D Quang, Alfred Gan, Haslina Hamzah, Renata Garcia-Franco, Ian Yew San Yeo, Shu Yen Lee, Edmund Yick Mun Wong, Charumathi Sabanayagam, Mani Baskaran, Farah Ibrahim, Ngiap Chuan Tan, Eric A Finkelstein, Ecosse L Lamoureux, Ian Y Wong, Neil M Bressler, Sobha Sivaprasad, et al.

Journal article | 2017 | JAMA

Association Between Perceived Barriers to Diabetes Self-management and Diabetic Retinopathy in Asian Patients With Type 2 Diabetes

Ryan Eyn Kidd Man, Eva K Fenwick, Alfred Tau Liang Gan, Charumathi Sabanayagam, Preeti Gupta, Amudha Aravindhan, Tien Yin Wong, Gavin Siew Wei Tan, Ecosse L Lamoureux

Journal article | 2017 | JAMA Ophthalmology

Global causes of blindness and distance vision impairment 1990-2020: a systematic review and meta-analysis

Seth R Flaxman, Rupert RA Bourne, Serge Resnikoff, Peter Ackland, Tasanee Braithwaite, Maria V Cicinelli, Aditi Das, Jost B Jonas, Jill Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Alex Silvester, Gretchen A Stevens, Nina Tahhan, Tien Y Wong, Hugh R Taylor

Journal article | 2017 | The Lancet Global Health

Innovative technology shows impact of glycaemic control on peripheral retinal vessels in adolescents with type 1 diabetes (Pg 2103, Vol 60, 2017)

Vahi Velayutham, Paul Z Benitez-Aguirre, Maria E Craig, Gerald Liew, Tien Y Wong, Alicia J Jenkins, Kim C Donaghue

Journal article | 2017 | Diabetologia

Diabetic Retinopathy and Macular Edema Quality-of-Life Item Banks: Development and Initial Evaluation Using Computerized Adaptive Testing

Eva K Fenwick, Jyoti Khadka, Konrad Pesudovs, Gwyn Rees, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2017 | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Is Corneal Arcus Independently Associated With Incident Cardiovascular Disease in Asians?

Mark Yu Zheng Wong, Ryan Eyn Kidd Man, Preeti Gupta, Sing Hui Lim, Blanche Lim, Yih-Chung Tham, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article | 2017 | American Journal of Ophthalmology

Myopic Choroidal Neovascularization Review, Guidance, and Consensus Statement on Management

Chui Ming Gemmy Cheung, Jennifer J Arnold, Frank G Holz, Kyu Hyung Park, Timothy YY Lai, Michael Larsen, Paul Mitchell, Kyoko Ohno-Matsui, Shih-Jen Chen, Sebastian Wolf, Tien Yin Wong

Journal article | 2017 | Ophthalmology

Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes

Charumathi Sabanayagam, Wanfen Yip, Preeti Gupta, Riswana BB Mohd Abdul, Ecosse Lamoureux, Neelam Kumari, Gemmy CM Cheung, Carol Y Cheung, Jie Jin Wang, Ching-Yu Cheng, Tien Yin Wong

Journal article | 2017 | Clinical & Experimental Ophthalmology

Availability and variability in guidelines on diabetic retinopathy screening in Asian countries

Louis Zizhao Wang, Carol Y Cheung, Robyn J Tapp, Haslina Hamzah, Gavin Tan, Daniel Ting, Ecosse Lamoureux, Tien Yin Wong

Journal article | 2017 | British Journal of Ophthalmology

Innovative technology shows impact of glycaemic control on peripheral retinal vessels in adolescents with type 1 diabetes

Valli Velayutham, Paul Z Benitez-Aguirre, Maria E Craig, Gerald Liew, Tien Y Wong, Alicia J Jenkins, Kim C Donaghue

Journal article | 2017 | Diabetologia

Incidence and risk factors of symptomatic dry eye disease in Asian Malays from the Singapore Malay Eye Study

Ryan EK Man, Anuradha R Veerappan, Shu-Pei Tan, Eva K Fenwick, Charumathi Sabanayagam, Jacqueline Chua, Yuan-Yuh Leong, Tien Yin Wong, Ecosse L Lamoureux, Ching-Yu Cheng, Louis Tong

Journal article | 2017 | The Ocular Surface

Characterization of choroidal morphological and vascular features in diabetes and diabetic retinopathy (vol 101, pg 1038, 2017)

Preeti Gupta, Sri Gowtham Thakku, Charumathi Sabanayagam, Gavin Tan, Rupesh Agrawal, Chui Ming Gemmy Cheung, Ecosse L Lamoureux, Tien-Yin Wong, Ching-Yu Cheng

Journal article | 2017 | British Journal of Ophthalmology

Prevalence of Diabetic Retinopathy and Blindness in Indonesian Adults With Type 2 Diabetes

Muhammad Bayu Sasongko, Felicia Widyaputri, Angela Nurini Agni, Firman Setya Wardhana, Satyaprabha Kotha, Prateek Gupta, Tri Wahyu Widayanti, Supanji Haryanto, Rifa Widyaningrum, Tien Yin Wong, Ryo Kawasaki, Jie Jin Wang

Journal article | 2017 | American Journal of Ophthalmology

Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis

Rupert RA Bourne, Seth R Flaxman, Tasanee Braithwaite, Maria V Cicinelli, Aditi Das, Jost B Jonas, Jill Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Serge Resnikoff, Alex Silvester, Gretchen A Stevens, Nina Tahhan, Tien Y Wong, Hugh R Taylor

Journal article | 2017 | The Lancet Global Health

Retinal Vascular Imaging Markers and Incident Chronic Kidney Disease: A Prospective Cohort Study

Wanfen Yip, Peng Guan Ong, Boon Wee Teo, Carol Yim-lui Cheung, E Shyong Tai, Ching-Yu Cheng, Ecosse Lamoureux, Tien Yin Wong, Charumathi Sabanayagam

Journal article | 2017 | Scientific Reports

A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration

Kyoko Kawashima-Kumagai, Kenji Yamashiro, Munemitsu Yoshikawa, Masahiro Miyake, Gemmy Cheung Chui Ming, Qiao Fan, Jia Yu Koh, Masaaki Saito, Masako Sugahara-Kuroda, Maho Oishi, Yumiko Akagi-Kurashige, Isao Nakata, Hideo Nakanishi, Norimoto Gotoh, Akio Oishi, Hiroshi Tamura, Sotaro Ooto, Akitaka Tsujikawa, Yasuo Kurimoto, Tetsuju Sekiryu, et al.

Journal article | 2017 | Scientific Reports

Characterisation of choroidal morphological and vascular features in diabetes and diabetic retinopathy

Preeti Gupta, Sri Gowtham Thakku, Charumathi Sabanayagam, Gavin Tan, Chui Ming Gemmy Cheung, Ecosse L Lamoureux, Tien-Yin Wong, Ching-Yu Cheng

Journal article | 2017 | British Journal of Ophthalmology

Frequency of Evidence-Based Screening for Diabetic Retinopathy

Ecosse L Lamoureux, Hugh Taylor, Tien Y Wong

Journal article | 2017 | New England Journal of Medicine

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Tin Aung, Mineo Ozaki, Mei Chin Lee, Ursula Schlotzer-Schrehardt, Gudmar Thorleifsson, Takanori Mizoguchi, Robert P Igo, Aravind Haripriya, Susan E Williams, Yury S Astakhov, Andrew C Orr, Kathryn P Burdon, Satoko Nakano, Kazuhiko Mori, Khaled Abu-Amero, Michael Hauser, Zheng Li, Gopalakrishnan Prakadeeswari, Jessica N Cooke Bailey, Alina Popa Cherecheanu, et al.

Journal article | 2017 | Nature Genetics

Combined poor diabetes control indicators are associated with higher risks of diabetic retinopathy and macular edema than poor glycemic control alone

Eva K Fenwick, Jing Xie, Ryan EK Man, Charumathi Sabanayagam, Lyndell Lim, Gwyn Rees, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2017 | PLOS ONE

Short-term poor glycemic control and retinal microvascular changes in pediatric Type 1 Diabetes patients in Singapore: a pilot study

Ling-Jun Li, Ecosse Lamoureux, Tien Yin Wong, Ngee Lek

Journal article | 2017 | BMC Ophthalmology

Vision impairment and major eye diseases reduce vision-specific emotional well-being in a Chinese population

Eva K Fenwick, Peng Guan Ong, Ryan EK Man, Charumathi Sabanayagam, Ching-Yu Cheng, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2017 | British Journal of Ophthalmology

Urinary Isoprostane Levels and Age-Related Macular Degeneration

Charumathi Sabanayagam, Weng Kit Lye, Andrzej Januszewski, Riswana Banu Binte Mohammed Abdul, Gemmy Chui Ming Cheung, Neelam Kumari, Tien Y Wong, Ching-Yu Cheng, Ecosse Lamoureux

Journal article | 2017 | Investigative Opthalmology & Visual Science

Progressive Retinal Vasodilation in Patients With Type 1 Diabetes: A Longitudinal Study of Retinal Vascular Geometry

Gerald Liew, Paul Benitez-Aguirre, Maria E Craig, Alicia J Jenkins, Lauren AB Hodgson, Annette Kifley, Paul Mitchell, Tien Y Wong, Kim Donaghue

Journal article | 2017 | Investigative Opthalmology & Visual Science

Cumulative incidence and risk factors of prediabetes and type 2 diabetes in a Singaporean Malay cohort

Ryan EK Man, Sabanayagam Charumathi, Alfred Tau Liang Gan, Eva K Fenwick, Ching Siong Tey, Jacqueline Chua, Tien-Yin Wong, Ching-Yu Cheng, Ecosse L Lamoureux

Journal article | 2017 | Diabetes Research and Clinical Practice

The impact of typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy on vision-related quality of life in Asian patients

Eva K Fenwick, Chui Ming Gemmy Cheung, Peng Guan Ong, Gavin Tan, Shu Yen Lee, Ian Yeo, Ching Yu Cheng, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2017 | British Journal of Ophthalmology

Ethnic Differences in the Association Between Age-Related Macular Degeneration and Vision-Specific Functioning

Eva K Fenwick, Ryan EK Man, Chui Ming Gemmy Cheung, Charumathi Sabanayagam, Ching-Yu Cheng, Kumari Neelam, Jacqueline Chua, Alfred TL Gan, Paul Mitchell, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2017 | JAMA Ophthalmology

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

Philip C Haycock, Stephen Burgess, Aayah Nounu, Jie Zheng, George N Okoli, Jack Bowden, Kaitlin Hazel Wade, Nicholas J Timpson, David M Evans, Peter Willeit, Abraham Aviv, Tomr Gaunt, Gibran Hemani, Massimo Mangino, Hayley Patricia Ellis, Kathreena M Kurian, Karen A Pooley, Rosalind A Eeles, Jeffrey E Lee, Shenying Fang, et al.

Journal article | 2017 | JAMA Oncology

Reply

KS Naidoo, TR Fricke, DA Wilson, M Jong, P Sankaridurg, TY Wong, TJ Naduvilath, S Resnikoff

Journal article | 2017 | Ophthalmology

Biometric authentication system using retinal vessel pattern and geometric hashing

Alauddin Bhuiyan, Akter Hussain, Ajmal Mian, Tien Y Wong, Kotagiri Ramamohanarao, Yogesan Kanagasingam

Journal article | 2017 | IET Biometrics

Prevalence and Determinants of Suboptimal Vitamin D Levels in a Multiethnic Asian Population

Ryan Eyn Kidd Man, Ling-Jun Li, Ching-Yu Cheng, Tien Yin Wong, Ecosse Lamoureux, Charumathi Sabanayagam

Journal article | 2017 | Nutrients

Reducing respondent burden: validation of the Brief Impact of Vision Impairment questionnaire

Eva K Fenwick, Ryan EK Man, Gwyn Rees, Jill Keeffe, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2017 | Quality of Life Research

An anomaly detection approach for the identification of DME patients using spectral domain optical coherence tomography images

Desire Sidibe, Shrinivasan Sankar, Guillaume Lemaitre, Mojdeh Rastgoo, Joan Massich, Carol Y Cheung, Gavin SW Tan, Dan Milea, Ecosse Lamoureux, Tien Y Wong, Fabrice Meriaudeau

Journal article | 2017 | Computer Methods and Programs in Biomedicine

Rationale and Methodology for a Community-Based Study of Diabetic Retinopathy in an Indonesian Population with Type 2 Diabetes Mellitus: The Jogjakarta Eye Diabetic Study in the Community

Muhammad B Sasongko, Angela N Agni, Firman S Wardhana, Satya P Kotha, Prateek Gupta, Tri W Widayanti, undefined Supanji, Felicia Widyaputri, Rifa Widyaningrum, Tien Y Wong, Ryo Kawasaki, Jie Jin Wang, Suhardjo Pawiroranu

Journal article | 2017 | Ophthalmic Epidemiology

HbA1c, systolic blood pressure variability and diabetic retinopathy in Asian type 2 diabetics

Valencia Foo, Joanne Quah, Gemmy Cheung, Ngiap Chun Tan, Kyi Lin Ma Zar, Choi Mun Chan, Ecosse Lamoureux, Tien Yin Wong, Gavin Tan, Charumathi Sabanayagam

Journal article | 2017 | Journal of Diabetes

Prevalence, Risk Factors, and Impact of Undiagnosed Visually Significant Cataract: The Singapore Epidemiology of Eye Diseases Study

Jacqueline Chua, Blanche Lim, Eva K Fenwick, Alfred Tau Liang Gan, Ava Grace Tan, Ecosse Lamoureux, Paul Mitchell, Jie Jin Wang, Tien Yin Wong, Ching-Yu Cheng

Journal article | 2017 | PLOS ONE

Effect of Axial Eye Length on Retinal Vessel Parameters in 6 to 12-Year-Old Malay Girls

Evelyn Li Min Tai, Ling-Jun Li, Wan Hitam Wan-Hazabbah, Tien-Yin Wong, Ismail Shatriah

Journal article | 2017 | PLOS ONE

Gestational diabetes mellitus and retinal microvasculature

Ling-Jun Li, Michael Kramer, Robyn J Tapp, Ryan EK Man, Ngee Lek, Shirong Cai, Fabian Yap, Peter Gluckman, Kok Hian Tan, Yap Seng Chong, Jia Yu Koh, Seang Mei Saw, Yin Bun Cheung, Tien Yin Wong

Journal article | 2017 | BMC Ophthalmology

Evidence of Microvascular Changes in the Retina following Kawasaki Disease

Katherine YH Chen, David P Burgner, Tien Y Wong, Seang Mei Saw, Swee Chye Quek, Audrey YC Pang, Seo Wei Leo, Inez B Wong, Diana Zannino, Nigel Curtis, Michael Cheung, Carol Y Cheung, Terence CW Lim

Journal article | 2017 | Scientific Reports

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

Henriet Springelkamp, Adriana I Iglesias, Aniket Mishra, Rene Hoehn, Robert Wojciechowski, Anthony P Khawaja, Abhishek Nag, Ya Xing Wang, Jie Jin Wang, Gabriel Cuellar-Partida, Jane Gibson, Jessica N Cooke Bailey, Eranga N Vithana, Puya Gharahkhani, Thibaud Boutin, Wishal D Ramdas, Tanja Zeller, Robert N Luben, Ekaterina Yonova-Doing, Ananth C Viswanathan, et al.

Journal article | 2017 | Human Molecular Genetics

Cost-effectiveness of a National Telemedicine Diabetic Retinopathy Screening Program in Singapore

Hai V Nguyen, Gavin Siew Wei Tan, Robyn Jennifer Tapp, Shweta Mital, Daniel Shu Wei Ting, Hon Tym Wong, Colin S Tan, Augustinus Laude, E Shyong Tai, Ngiap Chuan Tan, Eric A Finkelstein, Tien Yin Wong, Ecosse L Lamoureux

Journal article | 2016 | Ophthalmology

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Hieab HH Adams, Derrek P Hibar, Vincent Chouraki, Jason L Stein, Paul A Nyquist, Miguel E Renteria, Stella Trompet, Alejandro Arias-Vasquez, Sudha Seshadri, Sylvane Desrivieres, Ashley H Beecham, Neda Jahanshad, Katharine Wittfeld, Sven J Van der Lee, Lucija Abramovic, Saud Alhusaini, Najaf Amin, Micael Andersson, Konstantinos Arfanakis, Benjamin S Aribisala, et al.

Journal article | 2016 | Nature Neuroscience

Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos

Xiaoyi Gao, Drew R Nannini, Kristen Corrao, Mina Torres, Yii-Der I Chen, Bao J Fan, Janey L Wiggs, Kent D Taylor, W James Gauderman, Jerome I Rotter, Rohit Varma

Journal article | 2016 | Human Molecular Genetics

Association of Changes in Visual Acuity With Vision-Specific Functioning in the Singapore Malay Eye Study

Eva K Fenwick, Ryan EK Man, Peng Guan Ong, Charumathi Sabanayagam, Preeti Gupta, Ching-Yu Cheng, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2016 | JAMA Ophthalmology

Number of People Blind or Visually Impaired by Glaucoma Worldwide and in World Regions 1990-2010: A Meta-Analysis

Rupert RA Bourne, Hugh R Taylor, Seth R Flaxman, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Richard A White, Tien Y Wong, Serge Resnikoff, Jost B Jonas

Journal article | 2016 | PLOS ONE

Association of Vision Impairment and Major Eye Diseases With Mobility and Independence in a Chinese Population

Eva K Fenwick, Peng Guan Ong, Ryan Eyn Kidd Man, Ching-Yu Cheng, Charumathi Sabanayagam, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2016 | JAMA Ophthalmology

Global Estimates on the Number of People Blind or Visually Impaired by Diabetic Retinopathy: A Meta-analysis From 1990 to 2010

Janet L Leasher, Rupert RA Bourne, Seth R Flaxman, Jost B Jonas, Jill Keeffe, Kovin Naidoo, Konrad Pesudovs, Holly Price, Richard A White, Tien Y Wong, Serge Resnikoff, Hugh R Taylor

Journal article | 2016 | Diabetes Care

Differential Impact of Unilateral and Bilateral Classifications of Diabetic Retinopathy and Diabetic Macular Edema on Vision-Related Quality of Life

Ryan Eyn Kidd Man, Eva K Fenwick, Charumathi Sabanayagam, Ling-Jun Li, Ching Siong Tey, Hasita Jian Tai Soon, Gemmy Chui-Ming Cheung, Gavin Siew Wei Tan, Tien Yin Wong, Ecosse L Lamoureux

Journal article | 2016 | Investigative Opthalmology & Visual Science

Prevalence, Correlates, and Impact of Uncorrected Presbyopia in a Multiethnic Asian Population

Ryan Eyn Kidd Man, Eva Katie Fenwick, Charumathi Sabanayagam, Ling-Jun Li, Preeti Gupta, Yih-Chung Tham, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article | 2016 | American Journal of Ophthalmology

Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina

Xinyi Su, Queenie SW Tan, Bhav H Parikh, Alison Tan, Milan N Mehta, Yeo Sia Wey, Sai Bo Bo Tun, Ling-Jun Li, Xiao-Yan Han, Tien Y Wong, Walter Hunziker, Chi D Luu, Yuji Owada, Veluchamy A Barathi, Samuel S Zhang, Shyam S Chaurasia

Journal article | 2016 | Investigative Opthalmology & Visual Science

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

Qiao Fan, Xiaobo Guo, J Willem L Tideman, Katie M Williams, Seyhan Yazar, S Mohsen Hosseini, Laura D Howe, Beate St Pourcain, David M Evans, Nicholas J Timpson, George McMahon, Pirro G Hysi, Eva Krapohl, Ya Xing Wang, Jost B Jonas, Paul Nigel Baird, Jie Jin Wang, Ching-Yu Cheng, Yik-Ying Teo, Tien-Yin Wong, et al.

Journal article | 2016 | Scientific Reports

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

Chiea Chuen Khor, Tan Do, Hongyan Jia, Masakazu Nakano, Ronnie George, Khaled Abu-Amero, Roopam Duvesh, Li Jia Chen, Zheng Li, Monisha E Nongpiur, Shamira A Perera, Chunyan Qiao, Hon-Tym Wong, Hiroshi Sakai, Monica Barbosa de Melo, Mei-Chin Lee, Anita S Chan, Yaakub Azhany, Thi Lam Huong Dao, Yoko Ikeda, et al.

Journal article | 2016 | Nature Genetics

Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050

Brien A Holden, Timothy R Fricke, David A Wilson, Monica Jong, Kovin S Naidoo, Padmaja Sankaridurg, Tien Y Wong, Thomas J Naduvilath, Serge Resnikoff

Journal article | 2016 | Ophthalmology

Retinal ganglion cell neuronal damage in diabetes and diabetic retinopathy

Dorothy SK Ng, Peggy PC Chiang, Gavin Tan, CM Gemmy Cheung, Ching-Yu Cheng, Carol Y Cheung, Tien Y Wong, Ecosse L Lamoureux, Mohammad K Ikram

Journal article | 2016 | Clinical & Experimental Ophthalmology

Assessment of the psychometric properties of the Chinese Impact of Vision Impairment questionnaire in a population-based study: findings from the Singapore Chinese Eye Study

Eva K Fenwick, Peng Guan Ong, Charumathi Sabanayagam, Gwyn Rees, Jing Xie, Edith Holloway, Ching-Yu Cheng, Tien Y Wong, Blanche Lim, Pok Chien Tan, Ecosse L Lamoureux

Journal article | 2016 | Quality of Life Research

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

Qiao Fan, Virginie JM Verhoeven, Robert Wojciechowski, Veluchamy A Barathi, Pirro G Hysi, Jeremy A Guggenheim, Rene Hoehn, Veronique Vitart, Anthony P Khawaja, Kenji Yamashiro, S Mohsen Hosseini, Terho Lehtimaki, Yi Lu, Toomas Haller, Jing Xie, Cecile Delcourt, Mario Pirastu, Juho Wedenoja, Puya Gharahkhani, Cristina Venturini, et al.

Journal article | 2016 | Nature Communications

Diabetic retinopathy

Tien Y Wong, Chui Ming Gemmy Cheung, Michael Larsen, Sanjay Sharma, Rafael Simo

Journal article | 2016 | Australian Pharmacist

Differential Association of Generalized and Abdominal Obesity With Diabetic Retinopathy in Asian Patients With Type 2 Diabetes

Ryan Eyn Kidd Man, Charumathi Sabanayagam, Peggy Pei-Chia Chiang, Ling-Jun Li, Jonathan Edward Noonan, Jie Jin Wang, Tien Yin Wong, Gemmy Chui-Ming Cheung, Gavin Siew Wei Tan, Ecosse L Lamoureux

Journal article | 2016 | JAMA Ophthalmology

Global Vision Impairment and Blindness Due to Uncorrected Refractive Error, 1990-2010

Kovin S Naidoo, Janet Leasher, Rupert R Bourne, Seth R Flaxman, Jost B Jonas, Jill Keeffe, Hans Limburg, Konrad Pesudovs, Holly Price, Richard A White, Tien Y Wong, Hugh R Taylor, Serge Resnikoff

Journal article | 2016 | Optometry and Vision Science

Sleep apnea and retinal signs in cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

Merwyn Chew, Jing Xie, Ronald Klein, Barbara Klein, Mary Frances Cotch, Susan Redline, Tien Yin Wong, Ning Cheung

Journal article | 2016 | Sleep and Breathing

Relationship of ocular and systemic factors to the visibility of choroidal-scleral interface using spectral domain optical coherence tomography

Preeti Gupta, Ching-Yu Cheng, Chui Ming Gemmy Cheung, Hla Myint Htoon, Yingfeng Zheng, Ecosse L Lamoureux, Tin Aung, Tien-Yin Wong, Carol Y Cheung

Journal article | 2016 | Acta Ophthalmologica

Novel Genetic Loci Associated With Retinal Microvascular Diameter

Richard A Jensen, Xueling Sim, Albert Vernon Smith, Xiaohui Li, Johanna Jakobsdottir, Ching-Yu Cheng, Jennifer A Brody, Mary Frances Cotch, Barbara Mcknight, Ronald Klein, Jie Jin Wang, Annette Kifley, Tamara B Harris, Lenore J Launer, Kent D Taylor, Barbara EK Klein, Leslie J Raffel, Xiang Li, M Arfan Ikram, Caroline C Klaver, et al.

Journal article | 2016 | Circulation: Cardiovascular Genetics

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Jessica N Cooke Bailey, Stephanie J Loomis, Jae H Kang, R Rand Allingham, Puya Gharahkhani, Chiea Chuen Khor, Kathryn P Burdon, Hugues Aschard, Daniel I Chasman, Robert P Igo, Pirro G Hysi, Craig A Glastonbury, Allison Ashley-Koch, Murray Brilliant, Andrew A Brown, Donald L Budenz, Alfonso Buil, Ching-Yu Cheng, Hyon Choi, William G Christen, et al.

Journal article | 2016 | Nature Genetics

Suppression of inflammatory disease activity in rheumatoid arthritis is associated with improvements in retinal microvascular health

John Hsing-Yih Moi, Lauren AB Hodgson, Ian P Wicks, Tien Yin Wong, Sharon Van Doornum

Journal article | 2016 | Rheumatology

Retinal Vein Occlusion in a Multi-Ethnic Asian Population: The Singapore Epidemiology of Eye Disease Study

Victor Koh, Carol Y Cheung, Xiang Li, Dechao Tian, Jie Jin Wang, Paul Mitchell, Ching-Yu Cheng, Tien Y Wong

Journal article | 2016 | Ophthalmic Epidemiology

Hypertensive/Microvascular Disease and COPD: a Case Control Study

Sky KH Chew, Deb Colville, Piers Canty, Anastasia Hutchinson, Alex Wong, Luong Vi, Tien Y Wong, Christine McDonald, Judy Savige

Journal article | 2016 | Kidney and Blood Pressure Research

Classification of SD-OCT Volumes Using Local Binary Patterns: Experimental Validation for DME Detection

Guillaume Lemaitre, Mojdeh Rastgoo, Joan Massich, Carol Y Cheung, Tien Y Wong, Ecosse Lamoureux, Dan Milea, Fabrice Meriaudeau, Desire Sidibe

Journal article | 2016 | Journal of Ophthalmology

Retinal Vessel Tortuosity and Its Relation to Traditional and Novel Vascular Risk Markers in Persons with Diabetes

Muhammad Bayu Sasongko, Tien Yin Wong, Thanh T Nguyen, Carol Y Cheung, Jonathan E Shaw, Ryo Kawasaki, Ecosse L Lamoureux, Jie Jin Wang

Journal article | 2016 | Current Eye Research

Classification of SD-OCT volumes with multi pyramids, LBP and HOG descriptors: application to DME detections

Khaled Alsaih, Guillaume Lemaitre, Join Massich Vall, Mojdeh Rastgoo, Desire Sidibe, Tien Y Wong, Ecosse Lamoureux, Dan Milea, Carol Y Cheung, Fabrice Meriaudeau

Conference Proceedings | 2016 | 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Relationship Between Peripapillary Choroid and cl Retinal Nerve Fiber Layer Thickness in a Population-Based Sample of Nonglaucomatous Eyes

Preeti Gupta, Carol Y Cheung, Mani Baskaran, Jing Tian, Pina Marziliano, Ecosse L Lamoureux, Chui Ming Gemmy Cheung, Tin Aung, Tien Yin Wong, Ching-Yu Cheng

Journal article | 2016 | American Journal of Ophthalmology

Prevalence and determinants of undiagnosed diabetic retinopathy and vision-threatening retinopathy in a multiethnic Asian cohort: the Singapore Epidemiology of Eye Diseases (SEED) study

Olivia S Huang, Wan Ting Tay, Peng Guan Ong, Charumathi Sabanayagam, Ching-Yu Cheng, Gavin S Tan, Gemmy CM Cheung, Ecosse L Lamoureux, Tien Y Wong

Journal article | 2015 | British Journal of Ophthalmology

A Vision "Bolt-On" Item Could Increase the Discriminatory Power of the EQ-5D Index Score

Nan Luo, Xingzhi Wang, Marcus Ang, Eric A Finkelstein, Tin Aung, Tien-Yin Wong, Ecosse Lamoureux

Journal article | 2015 | Value in Health

Composite Measures of Individual and Area-Level Socio-Economic Status Are Associated with Visual Impairment in Singapore

Win Wah, Arul Earnest, Charumathi Sabanayagam, Ching-Yu Cheng, Marcus Eng Hock Ong, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2015 | PLOS ONE

Moderate consumption of white and fortified wine is associated with reduced odds of diabetic retinopathy

Eva K Fenwick, Jing Xie, Ryan Eyn Kidd Man, Lyndell L Lim, Victoria M Flood, Robert P Finger, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2015 | Journal of Diabetes and its Complications

Number of People Blind or Visually Impaired by Cataract Worldwide and in World Regions, 1990 to 2010

Moncef Khairallah, Rim Kahloun, Rupert Bourne, Hans Limburg, Seth R Flaxman, Jost B Jonas, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Holly Price, Richard A White, Tien Y Wong, Serge Resnikoff, Hugh R Taylor

Journal article | 2015 | Investigative Opthalmology & Visual Science

Exposure to Atomic Bomb Radiation and Age-Related Macular Degeneration in Later Life: The Hiroshima-Nagasaki Atomic Bomb Survivor Study

Katsumasa Itakura, Ikuno Takahashi, Eiji Nakashima, Masahide Yanagi, Ryo Kawasaki, Kazuo Neriishi, Jie Jin Wang, Tien Yin Wong, Ayumi Hida, Waka Ohishi, Yoshiaki Kiuchi

Journal article | 2015 | Investigative Opthalmology & Visual Science

Circulating markers of inflammation and endothelial function, and their relationship to diabetic retinopathy

MB Sasongko, TY Wong, AJ Jenkins, TT Nguyen, JE Shaw, JJ Wang

Journal article | 2015 | Diabetic medicine : a journal of the British Diabetic Association

Retinal Vessels Change in Primary Angle-Closure Glaucoma: The Handan Eye Study

Jianlu Gao, Yuanbo Liang, Fenghua Wang, Ran Shen, Tienyin Wong, Yi Peng, David S Friedman, Ningli Wang

Journal article | 2015 | SCIENTIFIC REPORTS

The Age-Specific Prevalence of Myopia in Asia: A Meta-analysis

Chen-Wei Pan, Mohamed Dirani, Ching-Yu Cheng, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2015 | Optometry and Vision Science

Glaucoma and Associated Visual Acuity and Field Loss Significantly Affect Glaucoma-Specific Psychosocial Functioning

Errol W Chan, Peggy PC Chiang, Jiemin Liao, Gwyneth Rees, Tien Y Wong, Janice SH Lam, Tin Aung, Ecosse Lamoureux

Journal article | 2015 | Ophthalmology

Usefulness of Retinal Microvascular Endothelial Dysfunction as a Predictor of Coronary Artery Disease

Ali H Al-Fiadh, Tien Y Wong, Ryo Kawasaki, David J Clark, Sheila K Patel, Melanie Freeman, Andrew Wilson, Louise M Burrell, Omar Farouque

Journal article | 2015 | The American Journal of Cardiology

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

Qing Li, Robert Wojciechowski, Claire L Simpson, Pirro G Hysi, Virginie JM Verhoeven, Mohammad Kamran Ikram, Rene Hoehn, Veronique Vitart, Alex W Hewitt, Konrad Oexle, Kari-Matti Makela, Stuart MacGregor, Mario Pirastu, Qiao Fan, Ching-Yu Cheng, Beat St Pourcain, George McMahon, John P Kemp, Kate Northstone, Jugnoo S Rahi, et al.

Journal article | 2015 | Human Genetics

Body mass index and retinopathy in Asian populations with diabetes mellitus

David Rooney, Weng Kit Lye, Gavin Tan, Ecosse L Lamoureux, Mohammad Kamran Ikram, Ching-Yu Cheng, Neelam Kumari, Ying Feng Zheng, Paul Mitchell, Jie Jin Wang, Tien Y Wong, Charumathi Sabanayagam

Journal article | 2015 | Acta Diabetologica

Erratum: A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome (Nature Genetics (2015) 47 (387-392))

T Aung, M Ozaki, T Mizoguchi, RR Allingham, Z Li, A Haripriya, S Nakano, S Uebe, JM Harder, ASY Chan, MC Lee, KP Burdon, YS Astakhov, KK Abu-Amero, JC Zenteno, Y Nilgün, T Zarnowski, M Pakravan, LA Safieh, L Jia, et al.

Journal article | 2015 | Nature Genetics

Microvascular Disease After Renal Transplantation

Qi Lun Ooi, Foong Kien Newk-Fon Hey Tow, Raj Deva, Ryo Kawasaki, Tien Y Wong, Deb Colville, Francesco Ierino, Anastasia Hutchinson, Judy Savige

Journal article | 2015 | Kidney and Blood Pressure Research

Sex Differences in Retinal Microvasculature Through Puberty In Type 1 Diabetes: Are Girls at Greater Risk of Diabetic Microvascular Complications?

Paul Benitez-Aguirre, Maria E Craig, Helene G Cass, Clare J Sugden, Alicia J Jenkins, Jie Jin Wang, Janine Cusumano, Lauren AB Hodgson, Kim Lee, Tien Yin Wong, Kim C Donaghue

Journal article | 2015 | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Development and Reliability of Retinal Arteriolar Central Light Reflex Quantification System: A New Approach for Severity Grading

Alauddin Bhuiyan, Carol Y Cheung, Shaun Frost, Ecosse Lamoureux, Paul Mitchell, Yogesan Kanagasingam, Tien Y Wong

Journal article | 2014 | Investigative Ophthalmology & Visual Science

Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract

Jiemin Liao, Xinyi Su, Peng Chen, Xu Wang, Liang Xu, Xiang Li, Lennard Thean, Clement Tan, Ava G Tan, Wan-Ting Tay, Gyungah Jun, Yingfeng Zheng, Merwyn Chew, Ya Xing Wang, Queenie S Tan, Veluchamy A Barathi, Barbara E Klein, Seang-Mei Saw, Eranga N Vithana, E-Shyong Tai, et al.

Journal article | 2014 | Human Molecular Genetics

Associations Between Depression and Anxiety Symptoms and Retinal Vessel Caliber in Adolescents and Young Adults

Madeline H Meier, Nathan A Gillespie, Narelle K Hansell, Alex W Hewitt, Ian B Hickie, Yi Lu, Stuart MacGregor, Sarah E Medland, Cong Sun, Tien Y Wong, Margaret J Wright, Gu Zhu, Nicholas G Martin, David A Mackey

Journal article | 2014 | Psychosomatic Medicine

Is chronic kidney disease associated with diabetic retinopathy in Asian adults?

Charumathi Sabanayagam, Valencia Hui Xian Foo, M Kamran Ikram, Huiqi Huang, Su Chi Lim, Ecosse L Lamoureux, E Shyong Tai, Tien Yin Wong

Journal article | 2014 | Journal of Diabetes

Retinal Vessel Calibers Predict Long-term Microvascular Complications in Type 1 Diabetes: The Danish Cohort of Pediatric Diabetes 1987 (DCPD1987)

Rebecca Broe, Malin L Rasmussen, Ulrik Frydkjaer-Olsen, Birthe S Olsen, Henrik B Mortensen, Lauren Hodgson, Tien Y Wong, Tunde Peto, Jakob Grauslund

Journal article | 2014 | Diabetes

Intraocular pressure rise is predictive of vision improvement after intravitreal triamcinolone acetonide for diabetic macular oedema: a retrospective analysis of data from a randomised controlled trial

Roderick F O'Day, Daniel Barthelmes, Meidong Zhu, Tien Y Wong, Ian L McAllister, Jennifer J Arnold, Mark C Gillies

Journal article | 2014 | BMC Ophthalmology

Visual Impairment and Blindness Due to Macular Diseases Globally: A Systematic Review and Meta-Analysis

Jost B Jonas, Rupert RA Bourne, Richard A White, Seth R Flaxman, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Holly Price, Tien Y Wong, Serge Resnikoff, Hugh R Taylor

Journal article | 2014 | American Journal of Ophthalmology

Differing associations of white matter lesions and lacunar infarction with retinal microvascular signs

Gerald Liew, Michelle L Baker, Tien Y Wong, Peter J Hand, Jie Jin Wang, Paul Mitchell, Deidre A De Silva, Meng-Cheong Wong, Elena Rochtchina, Richard I Lindley, Joanna M Wardlaw, Graeme J Hankey

Journal article | 2014 | International Journal of Stroke

Hemoglobin is Associated with Retinal Vascular Fractals in Type 1 Diabetes Patients

Mads Nybo, Lauren AB Hodgson, Ryo Kawasaki, Tien Yin Wong, Jakob Grauslund

Journal article | 2014 | Ophthalmic Epidemiology

Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci

Claire L Simpson, Robert Wojciechowski, Konrad Oexle, Federico Murgia, Laura Portas, Xiaohui Li, Virginie JM Verhoeven, Veronique Vitart, Maria Schache, S Mohsen Hosseini, Pirro G Hysi, Leslie J Raffel, Mary Frances Cotch, Emily Chew, Barbara EK Klein, Ronald Klein, Tien Yin Wong, Cornelia M Van Duijn, Paul Mitchell, Seang Mei Saw, et al.

Journal article | 2014 | PLoS ONE

Health Burden Associated with Visual Impairment in Singapore The Singapore Epidemiology of Eye Disease Study

Xingzhi Wang, Ecosse Lamoureux, Yingfeng Zheng, Marcus Ang, Tien Yin Wong, Nan Luo

Journal article | 2014 | Ophthalmology

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

Henriet Springelkamp, Rene Hoehn, Aniket Mishra, Pirro G Hysi, Chiea-Chuen Khor, Stephanie J Loomis, Jessica N Cooke Bailey, Jane Gibson, Gudmar Thorleifsson, Sarah F Janssen, Xiaoyan Luo, Wishal D Ramdas, Eranga Vithana, Monisha E Nongpiur, GrantW Montgomery, Liang Xu, Jenny E Mountain, Puya Gharahkhani, Yi Lu, Najaf Amin, et al.

Journal article | 2014 | Nature Communications

Is Renal Function Associated with Early Age-Related Macular Degeneration?

Elaine W Chong, Robyn H Guymer, Ronald Klein, Barbara E Klein, Mary Frances Cotch, Jie Jin Wang, Michael G Shlipak, Tien Y Wong

Journal article | 2014 | Optometry and Vision Science

Retinal Vascular Caliber and Age-related Macular Degeneration in an Indian Population from Singapore

You Chuen Chin, Tien Yin Wong, Chui Ming Gemmy Cheung, Carol Yim-Lui Cheung, Yingfeng Zheng, Paul Mitchell, HuiQi Huang, Jie Jin Wang, Mohammad Kamran Ikram

Journal article | 2014 | Ophthalmic Epidemiology

Early Signs of Exudative Age-Related Macular Degeneration in Asians

Mariko Sasaki, Ryo Kawasaki, Atsuro Uchida, Takashi Koto, Hajime Shinoda, Kazuo Tsubota, Tien Yin Wong, Yoko Ozawa

Journal article | 2014 | Optometry and Vision Science

Prevalence, Racial Variations, and Risk Factors of Age-Related Macular Degeneration in Singaporean Chinese, Indians, and Malays

Chui Ming Gemmy Cheung, Xiang Li, Ching-Yu Cheng, Yingfeng Zheng, Paul Mitchell, Jie Jin Wang, Tien Yin Wong

Journal article | 2014 | Ophthalmology

Complete Blood Count and Retinal Vessel Calibers

Gerald Liew, Jie Jin Wang, Elena Rochtchina, Tien Yin Wong, Paul Mitchell

Journal article | 2014 | PLoS ONE

Ethnic Variation in Early Age-Related Macular Degeneration Lesions Between White Australians and Singaporean Asians

Nichole Joachim, Paul Mitchell, Christine Younan, George Burlutsky, Ching-Yu Cheng, Chui Ming Gemmy Cheung, Yingfeng Zheng, Mireille Moffitt, Tien Yin Wong, Jie Jin Wang

Journal article | 2014 | Investigative Opthalmology & Visual Science

Estimated Cases of Blindness and Visual Impairment from Neovascular Age-Related Macular Degeneration Avoided in Australia by Ranibizumab Treatment

Paul Mitchell, Neil Bressler, Quan V Doan, Chantal Dolan, Alberto Ferreira, Aaron Osborne, Elena Rochtchina, Mark Danese, Shoshana Colman, Tien Y Wong

Journal article | 2014 | PLoS ONE

Prevalence and causes of vision loss in Central and South Asia: 1990-2010

Jost B Jonas, Ronnie George, Rashima Asokan, Seth R Flaxman, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Holly Price, Lingam Vijaya, Richard A White, Tien Y Wong, Serge Resnikoff, Hugh R Taylor, Rupert RA Bourne

Journal article | 2014 | British Journal of Ophthalmology

Prevalence and causes of vision loss in North Africa and the Middle East: 1990-2010

Moncef Khairallah, Rim Kahloun, Seth R Flaxman, Jost B Jonas, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Holly Price, Richard A White, Tien Yin Wong, Serge Resnikoff, Hugh R Taylor, Rupert R Bourne

Journal article | 2014 | British Journal of Ophthalmology

Prevalence and causes of vision loss in East Asia: 1990-2010

Tien Y Wong, Yingfeng Zheng, Jost B Jonas, Seth R Flaxman, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Holly Price, Richard A White, Serge Resnikoff, Hugh R Taylor, Rupert RA Bourne

Journal article | 2014 | British Journal of Ophthalmology

Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe: 1990-2010

Rupert RA Bourne, Jost B Jonas, Seth R Flaxman, Jill Keeffe, Janet Leasher, Kovin Naidoo, Maurizio B Parodi, Konrad Pesudovs, Holly Price, Richard A White, Tien Y Wong, Serge Resnikoff, Hugh R Taylor

Journal article | 2014 | British Journal of Ophthalmology

Prevalence and causes of vision loss in Latin America and the Caribbean: 1990-2010

Janet L Leasher, Van Lansingh, Seth R Flaxman, Jost B Jonas, Jill Keeffe, Kovin Naidoo, Konrad Pesudovs, Holly Price, Juan Carlos Silva, Richard A White, Tien Y Wong, Serge Resnikoff, Hugh R Taylor, Rupert RA Bourne

Journal article | 2014 | British Journal of Ophthalmology

Prevalence and causes of vision loss in Southeast Asia and Oceania: 1990-2010

J Keeffe, HR Taylor, K Fotis, K Pesudovs, SR Flaxman, JB Jonas, J Leasher, K Naidoo, H Price, RA White, TY Wong, S Resnikoff, RRA Bourne

Journal article | 2014 | British Journal of Ophthalmology

Ocular Anti-VEGF Therapy for Diabetic Retinopathy: Overview of Clinical Efficacy and Evolving Applications

Ning Cheung, Ian Y Wong, Tien Y Wong

Journal article | 2014 | Diabetes Care

Measurement of Macular Fractal Dimension Using a Computer-Assisted Program

George N Thomas, Shin-Yeu Ong, Yih Chung Tham, Wynne Hsu, Mong Li Lee, Qiangfeng Peter Lau, Wanting Tay, Jessica Alessi-Calandro, Lauren Hodgson, Ryo Kawasaki, Tien Yin Wong, Carol Y Cheung

Journal article | 2014 | Investigative Ophthalmology and Visual Science

Effect of Fenofibrate in Hyperglycemic Mice Retina: Role of downstream Inflammatory Cytokines in Diabetic Retinopathy

Veluchamy A Barathi, Yeo Sia Wey, Chi D Luu, Tien Y Wong, Shyam S Chaurasia, Ecosse L Lamoureux

Conference Proceedings | 2014 | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma

Monisha E Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K Cornes, Li-Jia Chen, Chunyan Qiao, K Saidas Nair, Ching-Yu Cheng, Liang Xu, Ronnie George, Tan Do, Khaled Abu-Amero, Shamira A Perera, Mineo Ozaki, Takanori Mizoguchi, Yasuo Kurimoto, Sancy Low, Liza-Sharmini A Tajudin, Ching-Lin Ho, Clement CY Tham, et al.

Journal article | 2014 | PLOS GENETICS

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Anubha Mahajan, Min Jin Go, Weihua Zhang, Jennifer E Below, Kyle J Gaulton, Teresa Ferreira, Momoko Horikoshi, Andrew D Johnson, Maggie CY Ng, Inga Prokopenko, Danish Saleheen, Xu Wang, Eleftheria Zeggini, Goncalo R Abecasis, Linda S Adair, Peter Almgren, Mustafa Atalay, Tin Aung, Damiano Baldassarre, Beverley Balkau, et al.

Journal article | 2014 | Nature Genetics

Evolving Practice Patterns in Treatment of Major Retinal Diseases in Singapore

Kelvin YC Teo, Gemmy CM Cheung, Shu Yen Lee, Adrian CH Koh, Sze Guan Ong, Tien Yin Wong

Journal article | 2014 | Academy of Medicine, Singapore - Annals

Marital status and its relationship with the risk and pattern of visual impairment in a multi-ethnic Asian population

Yingfeng Zheng, Ecosse L Lamoureux, Peggy PC Chiang, Ainur Rahman Anuar, Tien Y Wong

Journal article | 2014 | Journal of Public Health

Retinal vascular caliber and the development of hypertension: a meta-analysis of individual participant data

Jie Ding, Khin Lay Wai, Kevin McGeechan, M Kamran Ikram, Ryo Kawasaki, Jing Xie, Ronald Klein, Barbara BK Klein, Mary Frances Cotch, Jie Jin Wang, Paul Mitchell, Jonathan E Shaw, Kayama Takamasa, A Richey Sharrett, Tien Y Wong

Journal article | 2014 | JOURNAL OF HYPERTENSION

Retinal artery and venular caliber grading: A semi-automated evaluation tool

Alauddin Bhuiyan, Chandan Karmakar, Ryo Kawasaki, Ecosse Lamoureux, Kotagiri Ramamohanarao, Yogesan Kanagasingam, Tien Y Wong

Journal article | 2014 | Computers in Biology and Medicine

Retinal Vascular Fractal Dimension Is Associated with Cognitive Dysfunction

Carol Yim-lui Cheung, ShinYeu Ong, M Kamran Ikram, Yi Ting Ong, Christopher P Chen, N Venketasubramanian, Tien Yin Wong

Journal article | 2014 | Journal of Stroke & Cerebrovascular Diseases

Effects of Simvastatin on Retinal Structure and Function of a High-Fat Atherogenic Mouse Model of Thickened Bruch's Membrane

Veluchamy A Barathi, Sia W Yeo, Robyn H Guymer, Tien Y Wong, Chi D Luu

Journal article | 2014 | Investigative Ophthalmology and Visual Science

Randomized Controlled Trial of Intravitreal Ranibizumab Versus Standard Grid Laser for Macular Edema Following Branch Retinal Vein Occlusion

Mei Hong Tan, Ian L Mcallister, Mark E Gillies, Nitin Verma, Gayatri Banerjee, Lynne A Smithies, Wan-Ling Wong, Tien Y Wong

Journal article | 2014 | American Journal of Ophthalmology

Is the Association Between Smoking and the Retinal Venular Diameter Reversible Following Smoking Cessation?

Masahide Yanagi, Munechika Misumi, Ryo Kawasaki, Ikuno Takahashi, Katsumasa Itakura, Saeko Fujiwara, Masazumi Akahoshi, Kazuo Neriishi, Tien Yin Wong, Yoshiaki Kiuchi

Journal article | 2014 | Investigative Opthalmology & Visual Science

Validity of a new optic disc grading software for use in clinical and epidemiological research.

Yih-Chung Tham, Carol Y Cheung, Tien Y Wong, Mani Baskaran, Jiang Liu, Beng-Hai Lee, Fengshou Yin, Damon WK Wong, Jie Jin Wang, Paul Mitchell, Tin Aung, Ching-Yu Cheng

Journal article | 2013 | Clinical and Experimental Ophthalmology

BACKGROUND: To determine the reliability and agreement of a new optic disc grading software program for use in clinical, epidemiol..

Microvascular Abnormality in Schizophrenia as Shown by Retinal Imaging

Madeline H Meier, Idan Shalev, Terrie E Moffitt, Shitij Kapur, Richard SE Keefe, Tien Y Wong, Daniel W Belsky, Honalee Harrington, Sean Hogan, Renate Houts, Avshalom Caspi, Richie Poulton

Journal article | 2013 | American Journal of Psychiatry

Reliability and Reproducibility of Retinal Oxygen Saturation Measurements using a Predefined Peri-papillary Annulus

Ryan EK Man, Ryo Kawasaki, Zhichao Wu, Chi D Luu, Jie J Wang, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2013 | Acta Ophthalmologica (Print)

Determinants of Macular Thickness Using Spectral Domain Optical Coherence Tomography in Healthy Eyes: The Singapore Chinese Eye Study

Preeti Gupta, Elizabeth Sidhartha, Yih Chung Tham, Daniel Kai Peng Chua, Jiemin Liao, Ching-Yu Cheng, Tin Aung, Tien Yin Wong, Carol Y Cheung

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus

Peter Donnelly, Amy Strange, Celine Bellenguez, Xueling Sim, Robert Luben, Pirro G Hysi, Wishal D Ramdas, Leonieke ME van Koolwijk, Colin Freeman, Matti Pirinen, Zhan Su, Gavin Band, Richard Pearson, Damjan Vukcevic, Cordelia Langford, Panos Deloukas, Sarah Hunt, Emma Gray, Serge Dronov, Simon C Potter, et al.

Journal article | 2013 | Human Molecular Genetics

A Study Assessing the Association of Glycated Hemoglobin A(1C) (HbA(1C)) Associated Variants with HbA(1C), Chronic Kidney Disease and Diabetic Retinopathy in Populations of Asian Ancestry

Peng Chen, Rick Twee-Hee Ong, Wan-Ting Tay, Xueling Sim, Mohammad Ali, Haiyan Xu, Chen Suo, Jianjun Liu, Kee-Seng Chia, Eranga Vithana, Terri L Young, Tin Aung, Wei-Yen Lim, Chiea-Chuen Khor, Ching-Yu Cheng, Tien-Yin Wong, Yik-Ying Teo, E-Shyong Tai

Journal article | 2013 | PLoS One

The Relationship of Retinal Vessel Caliber With Erectile Dysfunction in Patients With Type 2 Diabetes

Sky KH Chew, Yamna Taouk, Jing Xie, Theona E Nicolaou, Jie J Wang, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.

Tanika N Kelly, Fumihiko Takeuchi, Yasuharu Tabara, Todd L Edwards, Young Jin Kim, Peng Chen, Huaixing Li, Ying Wu, Chi-Fan Yang, Yonghong Zhang, Dongfeng Gu, Tomohiro Katsuya, Takayoshi Ohkubo, Yu-Tang Gao, Min Jin Go, Yik Ying Teo, Ling Lu, Nanette R Lee, Li-Ching Chang, Hao Peng, et al.

Journal article | 2013 | Hypertension

We conducted a genome-wide association study meta-analysis of mean arterial pressure and pulse pressure among 26,600 East Asian pa..

Changes in Retinal Microvascular Caliber Precede the Clinical Onset of Preeclampsia

Samantha J Lupton, Christine L Chiu, Lauren AB Hodgson, Jane Tooher, Robert Ogle, Tien Yin Wong, Annemarie Hennessy, Joanne M Lind

Journal article | 2013 | Hypertension

Myopia and Age-Related Cataract: A Systematic Review and Meta-analysis

Chen-Wei Pan, Ching-Yu Cheng, Seang-Mei Saw, Jie Jin Wang, Tien Y Wong

Journal article | 2013 | American Journal of Ophthalmology

LOCALIZED CHANGES IN RETINAL VESSEL CALIBER AFTER FOCAL/GRID LASER TREATMENT IN PATIENTS WITH DIABETIC MACULAR EDEMA A Measure of Treatment Response?

Kristian Lundberg, Ryo Kawasaki, Anne K Sjolie, Tien Y Wong, Jakob Grauslund

Journal article | 2013 | Retina: the journal of retinal and vitreous diseases

Associations of Candidate Genes to Age-Related Macular Degeneration Among Racial/Ethnic Groups in the Multi-Ethnic Study of Atherosclerosis

Ronald Klein, Xiaohui Li, Jane Z Kuo, Barbara EK Klein, Mary Frances Cotch, Tien Y Wong, Kent D Taylor, Jerome I Rotter

Journal article | 2013 | American Journal of Ophthalmology

Prevalence of Cataract Surgery and Visual Outcomes in Indian Immigrants in Singapore: The Singapore Indian Eye Study

Preeti Gupta, Yingfeng Zheng, Tay Wan Ting, Ecosse L Lamoureux, Ching-Yu Cheng, Tien-Yin Wong

Journal article | 2013 | PLoS One

Hypertensive Retinopathy and Risk of Stroke

Yi-Ting Ong, Tien Y Wong, Ronald Klein, Barbara EK Klein, Paul Mitchell, A Richey Sharrett, David J Couper, M Kamran Ikram

Journal article | 2013 | Hypertension

Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations

Nora Franceschini, Ervin Fox, Zhaogong Zhang, Todd L Edwards, Michael A Nalls, Yun Ju Sung, Bamidele O Tayo, Yan V Sun, Omri Gottesman, Adebawole Adeyemo, Andrew D Johnson, J Hunter Young, Ken Rice, Qing Duan, Fang Chen, Yun Li, Hua Tang, Myriam Fornage, Keith L Keene, Jeanette S Andrews, et al.

Journal article | 2013 | American Journal of Human Genetics

Evaluation of item candidates for a diabetic retinopathy quality of life item bank

Eva K Fenwick, Konrad Pesudovs, Jyoti Khadka, Gwyn Rees, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2013 | QUALITY OF LIFE RESEARCH

Influence of blood pressure and body mass index on retinal vascular caliber in preschool-aged children

B Gopinath, JJ Wang, A Kifley, AG Tan, TY Wong, P Mitchell

Journal article | 2013 | Journal of Human Hypertension

Relationship between diabetic retinopathy, diabetic macular oedema and erectile dysfunction in type 2 diabetics

Sky KH Chew, Yamna Taouk, Jing Xie, Theona E Nicolaou, Jie Jin Wang, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2013 | Clinical and Experimental Ophthalmology

Is quality of diet associated with the microvasculature? An analysis of diet quality and retinal vascular calibre in older adults

Bamini Gopinath, Victoria M Flood, Jie Jin Wang, Elena Rochtchina, Tien Y Wong, Paul Mitchell

Journal article | 2013 | British Journal of Nutrition

Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

Ching-Yu Cheng, Maria Schache, M Kamran Ikram, Terri L Young, Jeremy A Guggenheim, Veronique Vitart, Stuart MacGregor, Virginie JM Verhoeven, Veluchamy A Barathi, Jiemin Liao, Pirro G Hysi, Joan E Bailey-Wilson, Beate St Pourcain, John P Kemp, George McMahon, Nicholas J Timpson, David M Evans, Grant W Montgomery, Aniket Mishra, Ya Xing Wang, et al.

Journal article | 2013 | American Journal of Human Genetics

Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular disease

Peggy PC Chiang, Ecosse L Lamoureux, Anoop Shankar, E Shyong Tai, Tien Y Wong, Charumathi Sabanayagam

Journal article | 2013 | BMC Public Health

Multiple vascular reactivity measures improves our ability to predict underlying coronary artery disease

A Alfiadh, N Uddin, S Patel, A Wilson, D Clark, R Kawasaki, L Burrell, T Wong, O Farouque

Conference Proceedings | 2013 | European Heart Journal

Effect of simvastatin on retinal vascular caliber: the Age-Related Maculopathy Statin Study

Mariko Sasaki, Wei Lin Gan, Ryo Kawasaki, Lauren Hodgson, Kim Yu Lee, Tien Yin Wong, Ecosse Lamoureux, Liubov Robman, Robyn Guymer

Journal article | 2013 | Acta Ophthalmologica (Print)

Utility of EQ-5D to Assess Patients Undergoing Cataract Surgery

Marcus Ang, Eva Fenwick, Tien Yin Wong, Ecosse Lamoureux, Nan Luo

Journal article | 2013 | Optometry and Vision Science

Baseline central macular thickness predicts the need for retreatment with intravitreal triamcinolone plus laser photocoagulation for diabetic macular edema

R O'Day, D Barthelmes, M Zhu, TY Wong, IL McAllister, JJ Arnold, MC Gillies

Journal article | 2013 | Clinical Ophthalmology

Prevalence, awareness, and control of hypertension among Asian Indians living in urban Singapore and rural India

WanFen Yip, Tien Y Wong, Jost B Jonas, Yingfeng Zheng, Ecosse L Lamoureux, Vinay Nangia, Charumathi Sabanayagam

Journal article | 2013 | Journal of Hypertension

Quantitative Measurement of Hard Exudates in Patients With Diabetes and Their Associations With Serum Lipid Levels

Mariko Sasaki, Ryo Kawasaki, Jonathan E Noonan, Tien Yin Wong, Ecosse Lamoureux, Jie Jin Wang

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore?

Rajkumar Dorajoo, Ruoying Li, Mohammad Kamran Ikram, Jianjun Liu, Philippe Froguel, Jeannette Lee, Xueling Sim, Rick Twee-Hee Ong, Wan Ting Tay, Chen Peng, Terri L Young, Alexandra IF Blakemore, Ching Yu Cheng, Tin Aung, Paul Mitchell, Jie Jin Wang, Caroline C Klaver, Eric Boerwinkle, Ronald Klein, David S Siscovick, et al.

Journal article | 2013 | PLoS One

Myopia, Axial Length, and Age-Related Cataract: The Singapore Malay Eye Study

Chen-Wei Pan, Pui Yi Boey, Ching-Yu Cheng, Seang-Mei Saw, Wan Ting Tay, Jie Jin Wang, Ava Grace Tan, Paul Mitchell, Tien Yin Wong

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

Dwight Stambolian, Robert Wojciechowski, Konrad Oexle, Mario Pirastu, Xiaohui Li, Leslie J Raffel, Mary Frances Cotch, Emily Y Chew, Barbara Klein, Ronald Klein, Tien Y Wong, Claire L Simpson, Caroline CW Klaver, Cornelia M van Duijn, Virginie JM Verhoeven, Paul N Baird, Veronique Vitart, Andrew D Paterson, Paul Mitchell, Seang Mei Saw, et al.

Journal article | 2013 | Human Molecular Genetics

Retinal artery-vein caliber grading using color fundus imaging

Alauddin Bhuiyan, Ryo Kawasaki, Ecosse Lamoureux, Kotagiri Ramamohanarao, Tien Yin Wong

Journal article | 2013 | Computer Methods and Programs in Biomedicine

Genetic Loci for Retinal Arteriolar Microcirculation

Xueling Sim, Richard A Jensen, M Kamran Ikram, Mary Frances Cotch, Xiaohui Li, Stuart MacGregor, Jing Xie, Albert Vernon Smith, Eric Boerwinkle, Paul Mitchell, Ronald Klein, Barbara EK Klein, Nicole L Glazer, Thomas Lumley, Barbara McKnight, Bruce M Psaty, Paulus TVM de Jong, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, et al.

Journal article | 2013 | PLoS One

Comparison of Anterior Segment Optical Tomography Parameters Measured Using a Semi-Automatic Software to Standard Clinical Instruments

Marcus Ang, Wesley Chong, Huiqi Huang, Wan Ting Tay, Tien Yin Wong, Ming-Guang He, Tin Aung, Jodhbir S Mehta

Journal article | 2013 | PLoS One

Is aspirin intake associated with early age-related macular degeneration? The Singapore Indian Eye Study

Ning Cheung, Wan-Ting Tay, Gemmy CM Cheung, Jie-Jin Wang, Paul Mitchell, Tien Y Wong

Journal article | 2013 | British Journal of Ophthalmology

Risk Factors for Strabismus and Amblyopia in Young Singapore Chinese Children

Audrey Chia, XiaoYu Lin, Mohamed Dirani, Gus Gazzard, Dharani Ramamurthy, Boon-Long Quah, Benjamin Chang, Yvonne Ling, Seo-Wei Leo, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2013 | Ophthalmic Epidemiology

Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4

RCW Ma, C Hu, CH Tam, R Zhang, P Kwan, TF Leung, GN Thomas, MJ Go, K Hara, X Sim, JSK Ho, C Wang, H Li, L Lu, Y Wang, JW Li, Y Wang, VKL Lam, J Wang, W Yu, et al.

Journal article | 2013 | Diabetologia

Retinal Venular Calibre is Increased in Patients with Autoimmune Rheumatic Disease: A Case-Control Study

Mali Okada, Tien Y Wong, Ryo Kawasaki, Norasyiqin Binti Baharuddin, Deb Colville, Russell Buchanan, Judy Savige

Journal article | 2013 | CURRENT EYE RESEARCH

Pathologic Changes in Highly Myopic Eyes of Young Males in Singapore

Victor TC Koh, Gerard KM Nah, Lan Chang, Adeline HX Yang, Sheng Tong Lin, Kyoko Ohno-Matsui, Tien Yin Wong, Seang Mei Saw

Journal article | 2013 | Academy of Medicine, Singapore - Annals

Branch retinal vein occlusion and optic nerve head topographic parameters: the Singapore Indian eye study

Errol Wei'en Chan, Tien Yin Wong, Jiemin Liao, Carol Yim-lui Cheung, Ying Feng Zheng, Jie Jin Wang, Paul Mitchell, Seng Chee Loon, Seang-Mei Saw, Tin Aung, Ching-Yu Cheng

Journal article | 2013 | British Journal of Ophthalmology

Hypertensive retinopathy: comparing the Keith-Wagener-Barker to a simplified classification

Laura E Downie, Lauren AB Hodgson, Carly D'Sylva, Rachel L McIntosh, Sophie L Rogers, Paul Connell, Tien Y Wong

Journal article | 2013 | JOURNAL OF HYPERTENSION

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Richa Saxena, Danish Saleheen, Latonya F Been, Martha L Garavito, Timothy Braun, Andrew Bjonnes, Robin Young, Weang Kee Ho, Asif Rasheed, Philippe Frossard, Xueling Sim, Neelam Hassanali, Venkatesan Radha, Manickam Chidambaram, Samuel Liju, Simon D Rees, Daniel Peng-Keat Ng, Tien-Yin Wong, Toshimasa Yamauchi, Kazuo Hara, et al.

Journal article | 2013 | Diabetes

Serum C-reactive protein level and prehypertension in two Asian populations

C Sabanayagam, A Shankar, J Lee, TY Wong, ES Tai

Journal article | 2013 | Journal of Human Hypertension

Prevalence and Risk Factors for Age-Related Macular Degeneration in Indians: A Comparative Study in Singapore and India

Chui Ming Gemmy Cheung, Xiang Li, Ching-Yu Cheng, Yingfeng Zheng, Paul Mitchell, Jie Jin Wang, Jost B Jonas, Vinay Nangia, Tien Yin Wong

Journal article | 2013 | American Journal of Ophthalmology

Systemic Associations of Dynamic Retinal Vessel Analysis: A Review of Current Literature

Michelle Lim, Muhammad B Sasongko, Mohammad K Ikram, Ecosse Lamoureux, Jie Jin Wang, Tien Yin Wong, Carol Y Cheung

Journal article | 2013 | Microcirculation

Seven new loci associated with age-related macular degeneration

Lars G Fritsche, Wei Chen, Matthew Schu, Brian L Yaspan, Yi Yu, Gudmar Thorleifsson, Donald J Zack, Satoshi Arakawa, Valentina Cipriani, Stephan Ripke, Robert P Igo, Gabrielle HS Buitendijk, Xueling Sim, Daniel E Weeks, Robyn H Guymer, Joanna E Merriam, Peter J Francis, Gregory Hannum, Anita Agarwal, Ana Maria Armbrecht, et al.

Journal article | 2013 | Nature Genetics

Impact of Bilateral Open and Closed-angle Glaucoma on Glaucoma-specific Functioning in Asians

Bingsong Wang, Tin Aung, Manjula Marella, Yingfeng Zheng, Tien Y Wong, Shamira Perera, Tina T Wong, Ching-Lin Ho, Ecosse L Lamoureux

Journal article | 2013 | Journal of Glaucoma

Temporal Changes in Retinal Microvascular Caliber and Blood Pressure During Pregnancy

Samantha J Lupton, Christine L Chiu, Lauren AB Hodgson, Jane Tooher, Sanja Lujic, Robert Ogle, Tien Yin Wong, Annemarie Hennessy, Joanne M Lind

Journal article | 2013 | Hypertension

Structural Changes in the Retinal Microvasculature and Renal Function

Laurence Shen Lim, Carol Yim-lui Cheung, Charumathi Sabanayagam, Su Chi Lim, E Shyong Tai, Lei Huang, Tien Yin Wong

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Virginie JM Verhoeven, Pirro G Hysi, Robert Wojciechowski, Qiao Fan, Jeremy A Guggenheim, Rene Hoehn, Stuart MacGregor, Alex W Hewitt, Abhishek Nag, Ching-Yu Cheng, Ekaterina Yonova-Doing, Xin Zhou, M Kamran Ikram, Gabrielle HS Buitendijk, George McMahon, John P Kemp, Beate St Pourcain, Claire L Simpson, Karl-Matti Makela, Terho Lehtimaki, et al.

Journal article | 2013 | Nature Genetics

Retinal Vascular Caliber as a Biomarker for Diabetes Microvascular Complications

M Kamran Ikram, Carol Y Cheung, Mara Lorenzi, Ronald Klein, Teresa LZ Jones, Tien Yin Wong

Journal article | 2013 | Diabetes Care

How Much Eye Care Services Do Asian Populations Need? Projection from the Singapore Epidemiology of Eye Disease (SEED) Study

Yingfeng Zheng, Ching-Yu Cheng, Ecosse L Lamoureux, Peggy PC Chiang, Ainur Rahman Anuar, Jie Jin Wang, Paul Mitchell, Seang-Mei Saw, Tien Y Wong

Journal article | 2013 | Investigative Ophthalmology and Visual Science

The Association of Aspirin Use With Age-Related Macular Degeneration

Gerald Liew, Paul Mitchell, Tien Yin Wong, Elena Rochtchina, Jie Jin Wang

Journal article | 2013 | JAMA Internal Medicine

Obesity and the Microvasculature: A Systematic Review and Meta-Analysis

Adrien Boillot, Sophia Zoungas, Paul Mitchell, Ronald Klein, Barbara Klein, Mohammad Kamran Ikram, Caroline Klaver, Jie Jin Wang, Bamini Gopinath, E Shyong Tai, Aljoscha Steffen Neubauer, Serge Hercberg, Laima Brazionis, Seang-Mei Saw, Tien-Yin Wong, Sebastien Czernichow

Journal article | 2013 | PLoS One

Genome-Wide Association Study of Retinopathy in Individuals without Diabetes

Richard A Jensen, Xueling Sim, Xiaohui Li, Mary Frances Cotch, M Kamran Ikram, Elizabeth G Holliday, Gudny Eiriksdottir, Tamara B Harris, Fridbert Jonasson, Barbara EK Klein, Lenore J Launer, Albert Vernon Smith, Eric Boerwinkle, Ning Cheung, Alex W Hewitt, Gerald Liew, Paul Mitchell, Jie Jin Wang, John Attia, Rodney Scott, et al.

Journal article | 2013 | PLoS One

Feasibility of screening for diabetic retinopathy at an Australian pathology collection service: a pilot study

Melanie F Larizza, Lauren A Hodgson, Eva K Fenwick, Ryo Kawasaki, Ralph Audehm, Jie Jin Wang, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2013 | MEDICAL JOURNAL OF AUSTRALIA

Frequency and risk factors of non-retinopathy ocular conditions in people with diabetes: the Singapore Malay Eye Study

PP-C Chiang, EL Lamoureux, Y Zheng, WT Tay, P Mitchell, JJ Wang, TY Wong

Journal article | 2013 | Diabetic Medicine

Impact of Glaucoma Severity and Laterality on Vision-Specific Functioning: The Singapore Malay Eye Study

Errol W Chan, Peggy PC Chiang, Tien Y Wong, Seang M Saw, Seng C Loon, Tin Aung, Ecosse Lamoureux

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Genetic Association of Refractive Error and Axial Length with 15q14 but Not 15q25 in the Blue Mountains Eye Study Cohort

Maria Schache, Andrea J Richardson, Paul Mitchell, Jie Jin Wang, Elena Rochtchina, Ananth C Viswanathan, Tien Y Wong, Seang Mei Saw, Fotis Topouzis, Jing Xie, Xueling Sim, Elizabeth C Holliday, John Attia, Rodney J Scott, Paul N Baird

Journal article | 2013 | Ophthalmology

Metabolic syndrome and mortality in the elderly: A time-dependent association

Haleh Ghaem Maralani, Bee Choo Tai, Tien Y Wong, E Shyong Tai, Jialiang Li, Jie Jin Wang, Paul Mitchell

Journal article | 2013 | Diabetes Research and Clinical Practice

New Systematic Review Methodology for Visual Impairment and Blindness for the 2010 Global Burden of Disease Study

Rupert Bourne, Holly Price, Hugh Taylor, Janet Leasher, Jill Keeffe, Julie Glanville, Pamela C Sieving, Moncef Khairallah, Tien YinWong, Yingfeng Zheng, Anu Mathew, Suchitra Katiyar, Maya Mascarenhas, Gretchen A Stevens, Serge Resnikoff, Stephen Gichuhi, Kovin Naidoo, Diane Wallace, Steven Kymes, Colleen Peters, et al.

Journal article | 2013 | Ophthalmic Epidemiology

Lack of Awareness of Common Eye Conditions in the Community

Olivia S Huang, Yingfeng Zheng, Wan Ting Tay, Peggy Pei-Chia Chiang, Ecosse L Lamoureux, Tien Y Wong

Journal article | 2013 | Ophthalmic Epidemiology

Antenatal Mental Health and Retinal Vascular Caliber in Pregnant Women

Ling-Jun Li, M Kamran Ikram, Leutscher Broekman, Carol Yim-Lui Cheung, Helen Chen, Joshua J Gooley, Shu-E Soh, Peter Gluckman, Kenneth Kwek, Yap-Seng Chong, Michael Meaney, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2013 | Translational Vision Science & Technology

The Association between Ocular Biometry and Retinal Vascular Caliber Is Comparable from Early Childhood to Adolescence

Bamini Gopinath, Jie Jin Wang, Annette Kifley, Ava G Tan, Tien Y Wong, Paul Mitchell

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Yi Lu, Veronique Vitart, Kathryn P Burdon, Chiea Chuen Khor, Yelena Bykhovskaya, Alireza Mirshahi, Alex W Hewitt, Demelza Koehn, Pirro G Hysi, Wishal D Ramdas, Tanja Zeller, Eranga N Vithana, Belinda K Cornes, Wan-Ting Tay, E Shyong Tai, Ching-Yu Cheng, Jianjun Liu, Jia-Nee Foo, Seang Mei Saw, Gudmar Thorleifsson, et al.

Journal article | 2013 | Nature Genetics

Vision Impairment and Major Causes of Vision Loss Impacts on Vision-Specific Functioning Independent of Socioeconomic Factors

Peggy PC Chiang, Yingfeng Zheng, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2013 | Ophthalmology

Differential Associations of Myopia with Major Age-related Eye Diseases The Singapore Indian Eye Study

Chen-Wei Pan, Carol Y Cheung, Tin Aung, Chiu-Ming Cheung, Ying-Feng Zheng, Ren-Yi Wu, Paul Mitchell, Raghavan Lavanya, Mani Baskaran, Jie Jin Wang, Tien Yin Wong, Seang-Mei Saw

Journal article | 2013 | Ophthalmology

Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis

Elizabeth G Holliday, Albert V Smith, Belinda K Cornes, Gabrielle HS Buitendijk, Richard A Jensen, Xueling Sim, Thor Aspelund, Tin Aung, Paul N Baird, Eric Boerwinkle, Ching Yu Cheng, Cornelia M van Duijn, Gudny Eiriksdottir, Vilmundur Gudnason, Tamara Harris, Alex W Hewitt, Michael Inouye, Fridbert Jonasson, Barbara EK Klein, Lenore Launer, et al.

Journal article | 2013 | PLoS One

Deep Whole-Genome Sequencing of 100 Southeast Asian Malays

Lai-Ping Wong, Rick Twee-Hee Ong, Wan-Ting Poh, Xuanyao Liu, Peng Chen, Ruoying Li, Kevin Koi-Yau Lam, Nisha Esakimuthu Pillai, Kar-Seng Sim, Haiyan Xu, Ngak-Leng Sim, Shu-Mei Teo, Jia-Nee Foo, Linda Wei-Lin Tan, Yenly Lim, Seok-Hwee Koo, Linda Seo-Hwee Gan, Ching-Yu Cheng, Sharon Wee, Eric Peng-Huat Yap, et al.

Journal article | 2013 | The American Journal of Human Genetics

Six-month visual prognosis in eyes with submacular hemorrhage secondary to age-related macular degeneration or polypoidal choroidal vasculopathy

Chui Ming Gemmy Cheung, Mayuri Bhargava, Li Xiang, Ranjana Mathur, Chan Choi Mun, Doric Wong, Tien Yin Wong

Journal article | 2013 | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Metabolic Syndrome and Risk of Age-Related Cataract over Time: An Analysis of Interval-Censored Data Using a Random-Effects Model

Haleh Ghaem Maralani, Bee Choo Tai, Tien Y Wong, E Shyong Tai, Jialiang Li, Jie Jin Wang, Paul Mitchell

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Retinal Vessel Caliber Is Associated with the 10-year Incidence of Glaucoma The Blue Mountains Eye Study

Ryo Kawasaki, Jie Jin Wang, Elena Rochtchina, Anne J Lee, Tien Yin Wong, Paul Mitchell

Journal article | 2013 | Ophthalmology

Automatic detection of retinal vascular landmark features for colour fundus image matching and patient longitudinal study

U Nguyen, A Bhuiyan, LAF Park, R Kawasaki, TY Wong, R Kotagiri

Conference Proceedings | 2013 | Proceedings of the 2013 20th IEEE International Conference on Image Processing

Cataract Conversion Assessment using Lens Opacity Classification System III and Wisconsin Cataract Grading System

Wan Ling Wong, Xiang Li, Jialiang Li, Ching-Yu Cheng, Ecosse L Lamoureux, Jie Jin Wang, Carol Y Cheung, Tien Yin Wong

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Myopia and Cognitive Dysfunction: The Singapore Malay Eye Study

Shin-Yeu Ong, M Kamran Ikram, Benjamin Adam Haaland, Ching-Yu Cheng, Seang-Mei Saw, Tien Yin Wong, Carol Y Cheung

Journal article | 2013 | Investigative Ophthalmology and Visual Science

Automated quantification of retinal arteriovenous nicking from colour fundus images

U Nguyen, A Bhuiyan, LAF Park, R Kawasaki, TY Wong, JJ Wang, P Mitchell, R Kotagiri

Conference Proceedings | 2013 | Proceedings of the 35th Annual International Conference of the IEEE EMBS

Prevalence and associations of cataract in a rural Chinese adult population: the Handan Eye Study

Xin Rong Duan, Yuan Bo Liang, Ning Li Wang, Tien Yin Wong, Lan Ping Sun, Xiao Hui Yang, Qiu Shan Tao, Rui Zhi Yuan, David S Friedman

Journal article | 2013 | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Vitamin D Deficiency Is Not Associated with Changes in Retinal Geometric Parameters in Young People with Type 1 Diabetes

Myra Poon, Maria E Craig, Harleen Kaur, Janine Cusumano, Muhammad Bayu Sasongko, Tien Yin Wong, Kim C Donaghue

Journal article | 2013 | Journal of Diabetes Research

Obesity and the Microvasculature: A Systematic Review and Meta-Analysis

A Boillot, S Zoungas, P Mitchell, R Klein, B Klein, MK Ikram, C Klaver, JJ Wang, B Gopinath, ES Tai, AS Neubauer, S Hercberg, L Brazionis, SM Saw, TY Wong, S Czernichow

Journal article | 2013 | PLoS One

The relationship between retinal vessel calibre and knee cartilage and BMLs

Miranda L Davies-Tuck, Ryo Kawasaki, Anita Wluka, Tien Y Wong, Lauren Hodgson, Dallas R English, Graham G Giles, Flavia M Cicuttini

Journal article | 2012 | BMC MUSCULOSKELETAL DISORDERS

The Association of Systemic Microvascular Changes with Lung Function and Lung Density: A Cross-Sectional Study

Bianca Harris, Ronald Klein, Michael Jerosch-Herold, Eric A Hoffman, Firas S Ahmed, David R Jacobs, Barbara EK Klein, Tien Y Wong, Joao AC Lima, Mary Frances Cotch, Graham Barr

Journal article | 2012 | PLoS One

Retinal Arterioles Narrow with Increasing Duration of Anti-Retroviral Therapy in HIV Infection: A Novel Estimator of Vascular Risk in HIV?

Sophia Pathai, Helen A Weiss, Stephen D Lawn, Tunde Peto, Leris M D'Costa, Colin Cook, Tien Y Wong, Clare E Gilbert

Journal article | 2012 | PLoS One

Impact of long-term measures of glucose and blood pressure on the retinal microvasculature.

Christy L Avery, Anna Kucharska-Newton, Keri L Monda, A Richey Sharrett, Thomas H Mosley, Barbara E Klein, Mary Frances Cotch, Tien Y Wong, Ronald Klein

Journal article | 2012 | Atherosclerosis

OBJECTIVE: Retinopathy and retinal microvascular abnormalities are common in adult populations, yet few long-term predictors have ..

The Relationship between Growth Spurts and Myopia in Singapore Children

Vivien Cherng-Hui Yip, Chen-Wei Pan, Xiao-Yu Lin, Yung-Seng Lee, Gus Gazzard, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2012 | Investigative Ophthalmology and Visual Science

The relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients

DA De Silva, F-P Woon, JJF Manzano, EY Liu, H-M Chang, C Chen, JJ Wang, P Mitchell, BA Kingwell, JD Cameron, RI Lindley, TY Wong, M-C Wong

Journal article | 2012 | Journal of Human Hypertension

Peripapillary atrophy detection by sparse biologically inspired feature manifold.

Jun Cheng, Dacheng Tao, Jiang Liu, Damon Wing Kee Wong, Ngan-Meng Tan, Tien Yin Wong, Seang Mei Saw

Journal article | 2012 | IEEE TRANSACTIONS ON MEDICAL IMAGING

Peripapillary atrophy (PPA) is an atrophy of pre-existing retina tissue. Because of its association with eye diseases such as myop..

Determinants of Retinal Venular Diameter: The Beaver Dam Eye Study

Chelsea E Myers, Ronald Klein, Michael D Knudtson, Kristine E Lee, Ronald Gangnon, Tien Y Wong, Barbara EK Klein

Journal article | 2012 | Ophthalmology

Prevalence of Lens Opacities in Asian Malays

Ava Grace Tan, Wan Ting Tay, Paul Mitchell, Mya Sandar, Tin Aung, Seang-Mei Saw, Jie Jin Wang, Tien Yin Wong

Journal article | 2012 | Ophthalmic Epidemiology

Pentosidine levels in nonproteinuric diabetes associated with both low estimated glomerular filtration rate and cataract

XL Lim, BW Teo, BC Tai, TY Wong, DPK Ng

Journal article | 2012 | Diabetes, Metabolic Syndrome and Obesity: targets and therapy

Associations between metabolic syndrome and syndrome components and retinal microvascular signs in a rural Chinese population: the Handan Eye Study

Yang Zhao, Ke Yang, Fenghua Wang, Yuanbo Liang, Yi Peng, Ran Shen, Tienyin Wong, Ningli Wang

Journal article | 2012 | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The impact of diabetic retinopathy on quality of life: qualitative findings from an item bank development project

Eva K Fenwick, Konrad Pesudovs, Jyoti Khadka, Mohamed Dirani, Gwyn Rees, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2012 | QUALITY OF LIFE RESEARCH

Erratum to: The impact of diabetic retinopathy on quality of life: qualitative findings from an item bank development project.

EK Fenwick, K Pesudovs, J Khadka, M Dirani, G Rees, TY Wong, EL Lamoureux

Journal article | 2012 | Quality of Life Research

Retinal Microvascular Signs and Risk of Stroke The Multi-Ethnic Study of Atherosclerosis (MESA)

Ryo Kawasaki, Jing Xie, Ning Cheung, Ecosse Lamoureux, Ronald Klein, Barbara EK Klein, Mary Frances, A Richey Sharrett, Steven Shea, Tien Y Wong

Journal article | 2012 | Stroke

Prevalence and Risk Factors of Meibomian Gland Dysfunction: The Singapore Malay Eye Study

Jay JK Siak, Louis Tong, Wan Ling Wong, Howard Cajucom-Uy, Mohamad Rosman, Seang Mei Saw, Tien Yin Wong

Journal article | 2012 | Cornea

Accuracy of diabetic retinopathy screening by trained non-physician graders using non-mydriatic fundus camera

Mayuri Bhargava, Carol Yim-Lui Cheung, Charumathi Sabanayagam, Ryo Kawasaki, C Alex Harper, Ecosse L Lamoureux, Wai Leng Chow, Adrian Ee, Haslina Hamzah, Maisie Ho, Wanling Wong, Tien Yin Wong

Journal article | 2012 | Singapore Medical Journal

Intraocular Pressure and its Relationship to Ocular and Systemic Factors in a Healthy Chinese Rural Population: The Handan Eye Study

Qiang Zhou, Yuan Bo Liang, Tien Yin Wong, Xiao Hui Yang, Liying Lian, Dan Zhu, Lan Ping Sun, Ning Li Wang, David S Friedman

Journal article | 2012 | Ophthalmic Epidemiology

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma

Eranga N Vithana, Chiea-Chuen Khor, Chunyan Qiao, Monisha E Nongpiur, Ronnie George, Li-Jia Chen, Do Tan, Khaled K Abu-Amero, Chor Kai Huang, Sancy Low, Liza-Sharmini A Tajudin, Shamira A Perera, Ching-Yu Cheng, Liang Xu, Hongyan Jia, Ching-Lin Ho, Kar Seng Sim, Ren-Yi Wu, Clement CY Tham, Paul TK Chew, et al.

Journal article | 2012 | NATURE GENETICS

Retinal Vascular Fractal Dimension and Its Relationship With Cardiovascular and Ocular Risk Factors

Carol Y Cheung, George N Thomas, Wanting Tay, M Kamran Ikram, Wynne Hsu, Mong Li Lee, Qiangfeng Peter Lau, Tien Yin Wong

Journal article | 2012 | American Journal of Ophthalmology

Correlation and Reproducibility of Retinal Vascular Geometric Measurements for Stereoscopic Retinal Images of the Same Eyes

Muhammad Bayu Sasongko, Lauren AB Hodgson, Tien Y Wong, Ryo Kawasaki, Carol Y Cheung, Wynne Hsu, Mong Li Lee, Peter QF Lau, Paul Mitchell, Jie Jin Wang

Journal article | 2012 | Ophthalmic Epidemiology

Prevalence and Risk Factors of Diabetic Retinopathy in Migrant Indians in an Urbanized Society in Asia The Singapore Indian Eye Study

Yingfeng Zheng, Ecosse L Lamoureux, Raghavan Lavanya, Renyi Wu, M Kamran Ikram, Jie Jin Wang, Paul Mitchell, Ning Cheung, Tin Aung, Seang-Mei Saw, Tien Y Wong

Conference Proceedings | 2012 | Ophthalmology

Language barrier and its relationship to diabetes and diabetic retinopathy

Yingfeng Zheng, Ecosse L Lamoureux, Pei-Chia Peggy Chiang, Ainur Rahman Anuar, Jie Ding, Jie Jin Wang, Paul Mitchell, E-Shyong Tai, Tien Y Wong

Journal article | 2012 | BMC Public Health

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

Isao Nakata, Kenji Yamashiro, Yumiko Akagi-Kurashige, Masahiro Miyake, Kyoko Kumagai, Akitaka Tsujikawa, Ke Liu, Li Jia Chen, David TL Liu, Timothy YY Lai, Yoichi Sakurada, Seigo Yoneyama, Ching-Yu Cheng, Peter Cackett, Ian Y Yeo, Wan Ting Tay, Belinda K Cornes, Eranga N Vithana, Tin Aung, Keitaro Matsuo, et al.

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Choroidal neovascularization in pathological myopia.

Kumari Neelam, Chiu Ming Gemmy Cheung, Kyoko Ohno-Matsui, Timothy YY Lai, Tien Y Wong

Journal article | 2012 | Progress in Retinal and Eye Research

Myopic choroidal neovascularization (CNV) is one of the leading causes of visual impairment worldwide. The clinical and socioecono..

Effect of Maternal Body Mass Index on the Retinal Microvasculature in Pregnancy

Ling-Jun Li, Kamran Ikram, Carol Yim-Lui Cheung, Yung-Seng Lee, Lin-Jun Lee, Peter Gluckman, Keith M Godfrey, Yap-Seng Chong, Kenneth Kwek, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2012 | Obstetrics and Gynecology

Longer Axial Length Is Protective of Diabetic Retinopathy and Macular Edema

Ryan Eyn Kidd Man, Muhammad Bayu Sasongko, Sutharssna Sanmugasundram, Theona Nicolaou, Xie Jing, Jie Jin Wang, Tien Yin Wong, Ecosse L Lamoureux

Journal article | 2012 | Ophthalmology

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

Virginie JM Verhoeven, Pirro G Hysi, Seang-Mei Saw, Veronique Vitart, Alireza Mirshahi, Jeremy A Guggenheim, Mary Frances Cotch, Kenji Yamashiro, Paul N Baird, David A Mackey, Robert Wojciechowski, M Kamran Ikram, Alex W Hewitt, Priya Duggal, Sarayut Janmahasatian, Chiea-Chuen Khor, Qiao Fan, Xin Zhou, Terri L Young, E-Shyong Tai, et al.

Journal article | 2012 | Human Genetics

Asian age-related macular degeneration phenotyping study: rationale, design and protocol of a prospective cohort study

Chui Ming G Cheung, Mayuri Bhargava, Augustinus Laude, Adrian CH Koh, Li Xiang, Doric Wong, Thet Niang, Tock Han Lim, Lingam Gopal, Tien Y Wong

Journal article | 2012 | Clinical and Experimental Ophthalmology

Relationship of Blood Pressure and Other Factors to Serial Retinal Arteriolar Diameter Measurements Over Time The Beaver Dam Eye Study

Ronald Klein, Chelsea E Myers, Michael D Knudtson, Kristine E Lee, Ronald Gangnon, Tien Y Wong, Barbara EK Klein

Journal article | 2012 | Archives of Ophthalmology

Determinants of Ganglion Cell-Inner Plexiform Layer Thickness Measured by High-Definition Optical Coherence Tomography

Victor T Koh, Yih-Chung Tham, Carol Y Cheung, Wan-Ling Wong, Mani Baskaran, Seang-Mei Saw, Tien Y Wong, Tin Aung

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Variation in prevalence of myopia between generations of migrant indians living in Singapore.

Chen-Wei Pan, Ying-Feng Zheng, Tien-Yin Wong, Raghavan Lavanya, Ren-Yi Wu, Gus Gazzard, Seang-Mei Saw

Journal article | 2012 | American Journal of Ophthalmology

PURPOSE: To assess the influence of factors related to migration and acculturation on myopia in migrant Indians in Singapore. DESI..

Current epidemiology of diabetic retinopathy and diabetic macular edema.

Jie Ding, Tien Yin Wong

Journal article | 2012 | Current Diabetes Reports

With increasing global prevalence of diabetes, diabetic retinopathy (DR) is set to be the principle cause of vision impairment in ..

Prevalence of and racial differences in pterygium: a multiethnic population study in Asians.

Marcus Ang, Xiang Li, Wanling Wong, Yingfeng Zheng, Daniel Chua, Ainur Rahman, Seang-Mei Saw, Donald TH Tan, Tien Yin Wong

Journal article | 2012 | Ophthalmology

PURPOSE: To describe the prevalence and risk factors of pterygium in a multiethnic Asian population and to examine racial differen..

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

Yukinori Okada, Xueling Sim, Min Jin Go, Jer-Yuarn Wu, Dongfeng Gu, Fumihiko Takeuchi, Atsushi Takahashi, Shiro Maeda, Tatsuhiko Tsunoda, Peng Chen, Su-Chi Lim, Tien-Yin Wong, Jianjun Liu, Terri L Young, Tin Aung, Mark Seielstad, Yik-Ying Teo, Young Jin Kim, Jong-Young Lee, Bok-Ghee Han, et al.

Journal article | 2012 | Nature Genetics

Does Retinal Vascular Geometry Vary with Cardiac Cycle?

Hao Hao, Muhammad B Sasongko, Tien Y Wong, Mohd Zulfaezal Che Azemin, Behzad Aliahmad, Lauren Hodgson, Ryo Kawasaki, Carol Y Cheung, Jie Jin Wang, Dinesh K Kumar

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Singapore Malay Eye Study: rationale and methodology of 6-year follow-up study (SiMES-2)

Mohamad Rosman, Yingfeng Zheng, Wanling Wong, Ecosse Lamoureux, Seang-Mei Saw, Wan-Ting Tay, Jie Jin Wang, Paul Mitchell, E-Shyong Tai, Tien Y Wong

Journal article | 2012 | Clinical and Experimental Ophthalmology

Letter by Cheung et al Regarding Article, "Mild Retinopathy Is a Risk Factor for Cardiovascular Mortality in Japanese With and Without Hypertension: The Ibaraki Prefectural Health Study"

Ning Cheung, Tien Yin Wong

Journal article | 2012 | Circulation

Anterior Chamber Dimensions and Posterior Corneal Arc Length in Malay Eyes: An Anterior Segment Optical Coherence Tomography Study

Deborah KL Tan, Wesley Chong, Wan Ting Tay, Leonard H Yuen, Mingguang He, Tin Aung, Donald TH Tan, Tien Yin Wong, Jodhbir S Mehta

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Serum Apolipoproteins Are Associated With Systemic and Retinal Microvascular Function in People With Diabetes

Muhammad Bayu Sasongko, Tien Y Wong, Thanh T Nguyen, Ryo Kawasaki, Alicia J Jenkins, Jonathan Shaw, Carol Robinson, Jie Jin Wang

Journal article | 2012 | Diabetes

Visual Impairment, Age-Related Eye Diseases, and Cognitive Function The Singapore Malay Eye Study

Shin Yeu Ong, Carol Y Cheung, Xiang Li, Ecosse L Lamoureux, M Kamran Ikram, Jie Ding, Ching Yu Cheng, Benjamin Adam Haaland, Seang Mei Saw, Narayanaswamy Venketasubramanian, Christopher PL Chen, Tien Yin Wong

Journal article | 2012 | Archives of Ophthalmology

Blood Pressure and Retinal Microvascular Characteristics During Pregnancy Growing Up in Singapore Towards Healthy Outcomes (GUSTO) Study

Ling-Jun Li, Carol Yim-Lui Cheung, M Kamran Ikram, Peter Gluckman, Michael J Meaney, Yap-Seng Chong, Kenneth Kwek, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2012 | Hypertension

Retinal vascular changes following intravitreal ranibizumab injections for neovascular AMD over a 1-year period

SS Wickremasinghe, J Xie, RH Guymer, TY Wong, R Kawasaki, S Qureshi

Journal article | 2012 | Eye

Fenofibrate - A Potential Systemic Treatment for Diabetic Retinopathy?

Tien Yin Wong, Rafael Simo, Paul Mitchell

Journal article | 2012 | American Journal of Ophthalmology

The Impact of Cataract, Cataract Types, and Cataract Grades on Vision-Specific Functioning Using Rasch Analysis

Merwyn Chew, Peggy Pei-Chia Chiang, Yingfeng Zheng, Raghavan Lavanya, Renyi Wu, Seang Mei Saw, Tien Yin Wong, Ecosse L Lamoureux

Journal article | 2012 | American Journal of Ophthalmology

Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals.

Remya Robinson, Veluchamy A Barathi, Shyam S Chaurasia, Tien Y Wong, Timothy S Kern

Journal article | 2012 | Disease Models & Mechanisms

Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and one of the major causes of blindness world..

Genetic Variants on Chromosome 1q41 Influence Ocular Axial Length and High Myopia

Qiao Fan, Veluchamy A Barathi, Ching-Yu Cheng, Xin Zhou, Akira Meguro, Isao Nakata, Chiea-Chuen Khor, Liang-Kee Goh, Yi-Ju Li, Wan'e Lim, Candice EH Ho, Felicia Hawthorne, Yingfeng Zheng, Daniel Chua, Hidetoshi Inoko, Kenji Yamashiro, Kyoko Ohno-Matsui, Keitaro Matsuo, Fumihiko Matsuda, Eranga Vithana, et al.

Journal article | 2012 | PLoS Genetics

Determinants of Anterior Chamber Depth: The Singapore Chinese Eye Study

Chelvin C Sng, Li-Lian Foo, Ching-Yu Cheng, John C Allen, Mingguang He, Gita Krishnaswamy, Monisha E Nongpiur, David S Friedman, Tien Y Wong, Tin Aung

Journal article | 2012 | Ophthalmology

The impact of bilateral or unilateral cataract surgery on visual functioning: when does second eye cataract surgery benefit patients?

Anna CS Tan, Wan Ting Tay, Ying Feng Zheng, Ava Grace Tan, Jie Jin Wang, Paul Mitchell, Tien Yin Wong, Ecosse Luc Lamoureux

Journal article | 2012 | British Journal of Ophthalmology

Retinal microvascular abnormalities and cognitive function in Latino adults in Los Angeles.

Nicole M Gatto, Rohit Varma, Mina Torres, Tien Y Wong, Pam L Johnson, Freddi Segal-Gidan, Wendy J Mack

Journal article | 2012 | Ophthalmic Epidemiology

PURPOSE: Retinal vessels may provide a readily accessible surrogate approach to study vascular disease in brain small vessels. Pre..

Age-related macular degeneration and long-term risk of stroke subtypes.

M Kamran Ikram, Paul Mitchell, Ronald Klein, A Rickey Sharrett, David J Couper, Tien Y Wong

Journal article | 2012 | Stroke

BACKGROUND AND PURPOSE: We examined the relationship of age-related macular degeneration (AMD) with incident stroke, including str..

Quantitative Analysis of Retinal Vessel Attenuation in Eyes with Retinitis Pigmentosa

Yaling Ma, Ryo Kawasaki, Lucy P Dobson, Jonathan B Ruddle, Lisa S Kearns, Tien Y Wong, David A Mackey

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Ten-Year Evolution of Retinopathy Lesions in an Older Nondiabetic Population

Jie Jin Wang, Elena Rochtchina, Shweta Kaushik, Annette Kifley, Sudha Cugati, Tien Y Wong, Paul Mitchell

Journal article | 2012 | Archives of Ophthalmology

Effect of the Duration of Macular Edema on Clinical Outcomes in Retinal Vein Occlusion Treated with Dexamethasone Intravitreal Implant

Wei-Shi Yeh, Julia A Haller, Paolo Lanzetta, Baruch D Kuppermann, Tien Yin Wong, Paul Mitchell, Scott M Whitcup, Jonathan W Kowalski

Journal article | 2012 | Ophthalmology

Predicting Risk of Diabetic Retinopathy From Retinal Vessel Analysis Personalized Medicine in Transition

Ning Cheung, Tien Yin Wong

Journal article | 2012 | Archives of Ophthalmology

Lower incidence of vascular events following small artery ischemic stroke

Deidre Anne de Silva, Jennifer Justice Frogozo Manzano, April Toh, Fung-Peng Woon, Erica Yang Liu, Eunizar Omar, Wan-Xin Wong, Tien-Yin Wong, Christopher PLH Chen, Hui-Meng Chang, Meng-Cheong Wong

Journal article | 2012 | International Journal of Stroke

Relationship between a range of sedentary behaviours and blood pressure during early adolescence

B Gopinath, LA Baur, LL Hardy, A Kifley, KA Rose, TY Wong, P Mitchell

Journal article | 2012 | Journal of Human Hypertension

Are Linear Regression Techniques Appropriate for Analysis When the Dependent (Outcome) Variable Is Not Normally Distributed?

Xiang Li, Wanling Wong, Ecosse L Lamoureux, Tien Y Wong

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Multi-stage segmentation of white matter hyperintensity, cortical and lacunar infarcts.

Yanbo Wang, Joseree Ann Catindig, Saima Hilal, Hock Wei Soon, Eric Ting, Tien Yin Wong, Narayanaswamy Venketasubramanian, Christopher Chen, Anqi Qiu

Journal article | 2012 | Neuroimage

Cerebral abnormalities such as white matter hyperintensity (WMH), cortical infarct (CI), and lacunar infarct (LI) are of clinical ..

Retinal vascular calibre as a predictor of incidence and progression of diabetic retinopathy

Jie Ding, M Kamran Ikram, Carol Y Cheung, Tien Yin Wong

Journal article | 2012 | Clinical and Experimental Optometry

Carbohydrate nutrition is associated with changes in the retinal vascular structure and branching pattern in children

Bamini Gopinath, Victoria M Flood, Jie Jin Wang, Wayne Smith, Elena Rochtchina, Jimmy CY Louie, Tien Y Wong, Jennie Brand-Miller, Paul Mitchell

Journal article | 2012 | American Journal of Clinical Nutrition

Impact of diabetic retinopathy on patients' beliefs about diabetes

Gwyn Rees, Muhammad B Sasongko, Eva K Fenwick, Theona E Nicolaou, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2012 | Clinical and Experimental Optometry

Association of dilated retinal arteriolar caliber with early age-related macular degeneration: the Handan Eye Study

Ke Yang, Si Yan Zhan, Yuan Bo Liang, Xinrong Duan, Fenghua Wang, Tien Yin Wong, Lan Ping Sun, Ning-Li Wang

Journal article | 2012 | Graefe's Archive for Clinical and Experimental Ophthalmology

Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma

Leonieke ME van Koolwijk, Wishal D Ramdas, M Kamran Ikram, Nomdo M Jansonius, Francesca Pasutto, Pirro G Hysi, Stuart Macgregor, Sarah F Janssen, Alex W Hewitt, Ananth C Viswanathan, Jacoline B ten Brink, S Mohsen Hosseini, Najaf Amin, Dominiek DG Despriet, Jacqueline JM Willemse-Assink, Rogier Kramer, Fernando Rivadeneira, Maksim Struchalin, Yurii S Aulchenko, Nicole Weisschuh, et al.

Journal article | 2012 | PLoS Genetics

Retinal vascular geometry in Asian persons with diabetes and retinopathy.

Carol Yim-lui Cheung, Ecosse Lamoureux, M Kamran Ikram, M Bayu Sasongko, Jie Ding, Yingfeng Zheng, Paul Mitchell, Jie Jin Wang, Tien Yin Wong

Journal article | 2012 | Journal of Diabetes Science and Technology

PURPOSE: Our purpose was to examine the relationship of retinal vascular parameters with diabetes and retinopathy in an older Asia..

Early Retinal Arteriolar Changes and Peripheral Neuropathy in Diabetes

Jie Ding, Carol Y Cheung, M Kamran Ikram, Ying-Feng Zheng, Ching-Yu Cheng, Ecosse L Lamoureux, E Shyong Tai, Tavintharan Subramaniam, Tien Yin Wong

Journal article | 2012 | Diabetes Care

Anti-vascular endothelial growth factor treatment for eye diseases.

Ning Cheung, Dennis SC Lam, Tien Y Wong

Journal article | 2012 | British Medical Journal

Impact of Migration and Acculturation on Prevalence of Type 2 Diabetes and Related Eye Complications in Indians Living in a Newly Urbanised Society

Yingfeng Zheng, Ecosse L Lamoureux, M Kamran Ikram, Paul Mitchell, Jie Jin Wang, Christine Younan, Ainur Rahman Anuar, E-Shyong Tai, Tien Y Wong

Journal article | 2012 | PLoS One

A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations

Xu Wang, Xuanyao Liu, Xueling Sim, Haiyan Xu, Chiea-Chuen Khor, Rick Twee-Hee Ong, Wan-Ting Tay, Chen Suo, Wan-Ting Poh, Daniel Peng-Keat Ng, Jianjun Liu, Tin Aung, Kee-Seng Chia, Tien-Yin Wong, E-Shyong Tai, Yik-Ying Teo

Journal article | 2012 | European Journal of Human Genetics

Automated Analysis of Retinal Vascular Tortuosity on Color Retinal Images

Alauddin Bhuiyan, Baikunth Nath, Kotagiri Ramamohanarao, Ryo Kawasaki, Tien Yin Wong

Journal article | 2012 | Journal of Medical Systems

Comparison of scanning laser ophthalmoscopy and high-definition optical coherence tomography measurements of optic disc parameters.

Li-Lian Foo, Shamira A Perera, Carol Y Cheung, John C Allen, Yingfeng Zheng, Seng-Chee Loon, Tien Y Wong, Tin Aung

Journal article | 2012 | British Journal of Ophthalmology

OBJECTIVE: To investigate the agreement between scanning laser ophthalmoscopy (Heidelberg retinal tomograph 3; HRT-3) and high-def..

A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer.

King Pan Ng, Axel M Hillmer, Charles TH Chuah, Wen Chun Juan, Tun Kiat Ko, Audrey SM Teo, Pramila N Ariyaratne, Naoto Takahashi, Kenichi Sawada, Yao Fei, Sheila Soh, Wah Heng Lee, John WJ Huang, John C Allen, Xing Yi Woo, Niranjan Nagarajan, Vikrant Kumar, Anbupalam Thalamuthu, Wan Ting Poh, Ai Leen Ang, et al.

Journal article | 2012 | Nature Medicine

Tyrosine kinase inhibitors (TKIs) elicit high response rates among individuals with kinase-driven malignancies, including chronic ..

Republished article: The impact of diabetic retinopathy: understanding the patient's perspective

EK Fenwick, K Pesudovs, G Rees, M Dirani, R Kawasaki, TY Wong, EL Lamoureux

Journal article | 2012 | Postgraduate Medical Journal

Meta-analysis identifies common variants associated with body mass index in east Asians

Wanqing Wen, Yoon-Shin Cho, Wei Zheng, Rajkumar Dorajoo, Norihiro Kato, Lu Qi, Chien-Hsiun Chen, Ryan J Delahanty, Yukinori Okada, Yasuharu Tabara, Dongfeng Gu, Dingliang Zhu, Christopher A Haiman, Zengnan Mo, Yu-Tang Gao, Seang-Mei Saw, Min-Jin Go, Fumihiko Takeuchi, Li-Ching Chang, Yoshihiro Kokubo, et al.

Journal article | 2012 | Nature Genetics

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

Joanne WY Yau, Sophie L Rogers, Ryo Kawasaki, Ecosse L Lamoureux, Jonathan W Kowalski, Toke Bek, Shih-Jen Chen, Jacqueline M Dekker, Astrid Fletcher, Jakob Grauslund, Steven Haffner, Richard F Hamman, M Kamran Ikram, Takamasa Kayama, Barbara EK Klein, Ronald Klein, Sannapaneni Krishnaiah, Korapat Mayurasakorn, Joseph P O'Hare, Trevor J Orchard, et al.

Journal article | 2012 | Diabetes Care

Retinal Vascular Geometry Predicts Incident Renal Dysfunction in Young People With Type 1 Diabetes

Paul Z Benitez-Aguirre, Muhammad Bayu Sasongko, Maria E Craig, Alicia J Jenkins, Janine Cusumano, Ning Cheung, Tien Yin Wong, Kim C Donaghue

Journal article | 2012 | Diabetes Care

Novel versus traditional risk markers for diabetic retinopathy

MB Sasongko, TY Wong, TT Nguyen, JE Shaw, AJ Jenkins, JJ Wang

Journal article | 2012 | DIABETOLOGIA

Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion)

Christopher M Reid, Elsdon Storey, Tien Y Wong, Robyn Woods, Andrew Tonkin, Jie Jin Wang, Anthony Kam, Andrew Janke, Rowan Essex, Walter P Abhayaratna, Marc M Budge

Journal article | 2012 | BMC Neurology

Retinal venular calibre dilatation after intravitreal ranibizumab treatment for neovascular age-related macular degeneration

Sanjeewa S Wickremasinghe, Robyn H Guymer, Tien Y Wong, Ryo Kawasaki, Wanling Wong, Salmaan Qureshi

Journal article | 2012 | Clinical and Experimental Ophthalmology

Changing Trends of Blindness: The Initial Harvest From Translational Public Health and Clinical Research in Ophthalmology

Ning Cheung, Tien Yin Wong

Journal article | 2012 | American Journal of Ophthalmology

Methodology and early findings of the Diabetes Management Project: a cohort study investigating the barriers to optimal diabetes care in diabetic patients with and without diabetic retinopathy

Ecosse Luc Lamoureux, Eva Fenwick, Jing Xie, Annie Mcauley, Theona Nicolaou, Melanie Larizza, Gwyn Rees, Salmaan Qureshi, Tien Yin Wong, Rehab Benarous, Mohamed Dirani

Journal article | 2012 | Clinical and Experimental Ophthalmology

Prevalence and Risk Factors of Epiretinal Membrane in Asian Indians

Victor Koh, Carol Y Cheung, Wan-Ling Wong, Chui-Min Cheung, Jie Jin Wang, Paul Mitchell, Christine Younan, Seang Mei Saw, Tien Y Wong

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Review of key findings from the Singapore Malay Eye Study (SiMES-1)

M Rosman, Y Zheng, E Lamoureux, SM Saw, T Aung, WT Tay, JJ Wang, P Mitchell, ES Tai, TY Wong

Journal article | 2012 | Singapore Medical Journal

Social and emotional impact of diabetic retinopathy: a review

Eva Fenwick, Gwyn Rees, Konrad Pesudovs, Mohamed Dirani, Ryo Kawasaki, Tien Y Wong Franzco, Ecosse Lamoureux

Journal article | 2012 | Clinical and Experimental Ophthalmology

Retinal microvascular calibre and risk of incident diabetes: The multi-ethnic study of atherosclerosis

Joanne Wen Yee Yau, Jing Xie, Ecosse Lamoureux, Ronald Klein, Barbara EK Klein, Mary Frances Cotch, Alain G Bertoni, Steven Shea, Tien Y Wong

Journal article | 2012 | Diabetes Research and Clinical Practice

The Impact of Diabetic Retinopathy and Diabetic Macular Edema on Health-Related Quality of Life in Type 1 and Type 2 Diabetes

Eva K Fenwick, Jing Xie, Julie Ratcliffe, Konrad Pesudovs, Robert P Finger, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2012 | Investigative Ophthalmology and Visual Science

How does hypertension affect your eyes?

M Bhargava, MK Ikram, TY Wong

Journal article | 2012 | Journal of Human Hypertension

Comparing Stereometric Parameters Between Heidelberg Retinal Tomography 2 and 3 in Asian Eyes: The Singapore Malay Eye Study

Victor Koh, Seng Chee Loon, Wan-Ling Wong, Tien Y Wong, Tin Aung

Journal article | 2012 | Journal of Glaucoma

Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations

Belinda K Cornes, Chiea Chuen Khor, Monisha E Nongpiur, Liang Xu, Wan-Ting Tay, Yingfeng Zheng, Raghavan Lavanya, Yang Li, Renyi Wu, Xueling Sim, Ya-Xing Wang, Peng Chen, Yik Ying Teo, Kee-Seng Chia, Mark Seielstad, Jianjun Liu, Martin L Hibberd, Ching-Yu Cheng, Seang-Mei Saw, E-Shyong Tai, et al.

Journal article | 2012 | Human Molecular Genetics

Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals

B Xi, F Takeuchi, GR Chandak, N Kato, HW Pan, DH Zhou, HY Pan, J Mi

Journal article | 2012 | Diabetologia

Aims/hypothesis: Genome-wide association studies have shown that variants near the melanocortin 4 receptor gene (MC4R) (rs17782313..

Characteristics and appearance of the normal optic nerve head in 6-year-old children

Chameen Samarawickrama, Amy Pai, Yasser Tariq, Paul R Healey, Tien Y Wong, Paul Mitchell

Journal article | 2012 | British Journal of Ophthalmology

Natural positive selection and north-south genetic diversity in East Asia

Chen Suo, Haiyan Xu, Chiea-Chuen Khor, Rick TH Ong, Xueling Sim, Jieming Chen, Wan-Ting Tay, Kar-Seng Sim, Yi-Xin Zeng, Xuejun Zhang, Jianjun Liu, E-Shyong Tai, Tien-Yin Wong, Kee-Seng Chia, Yik-Ying Teo

Journal article | 2012 | European Journal of Human Genetics

Retinal Arteriolar Tortuosity is Associated With Retinopathy and Early Kidney Dysfunction in Type 1 Diabetes

Muhammad Bayu Sasongko, Tien Yin Wong, Kim C Donaghue, Ning Cheung, Alicia J Jenkins, Paul Benitez-Aguirre, Jie Jin Wang

Journal article | 2012 | American Journal of Ophthalmology

Amblyopia Prevalence and Risk Factors in Australian Preschool Children

Amy Shih-I Pai, Kathryn A Rose, Jody F Leone, Sharimawati Sharbini, George Burlutsky, Rohit Varma, Tien Yin Wong, Paul Mitchell

Journal article | 2012 | Ophthalmology

Retinal Microvascular Signs Are Associated with Chronic Kidney Disease in Persons with and without Diabetes

G Liew, P Mitchell, TY Wong, JJ Wang

Journal article | 2012 | Kidney & Blood Pressure Research

Lipids and diabetic retinopathy

Laurence S Lim, Tien Y Wong

Journal article | 2012 | Expert Opinion on Biological Therapy

Influence of diabetes on macular thickness measured using optical coherence tomography: The Singapore Indian Eye Study

CCA Sng, CY Cheung, RE Man, W Wong, R Lavanya, P Mitchell, T Aung, TY Wong

Journal article | 2012 | Eye

Elevated Blood Pressure is Associated with Rarefaction of the Retinal Vasculature in Children

Emil D Kurniawan, Ning Cheung, Carol Y Cheung, Wan Ting Tay, Seang Mei Saw, Tien Yin Wong

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Anterior Segment Optical Coherence Tomography Study of the Cornea and Anterior Segment in Adult Ethnic South Asian Indian Eyes

Marcus Ang, Wesley Chong, Wan Ting Tay, Leonard Yuen, Tien Yin Wong, Ming-Guang He, Seang Mei Saw, Tin Aung, Jodhbir S Mehta

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Retinal Venular Caliber Predicts Visual Outcome after Intravitreal Ranibizumab Injection Treatments for Neovascular AMD

Sanjeewa S Wickremasinghe, Lucy Busija, Robyn H Guymer, Tien Y Wong, Salmaan Qureshi

Journal article | 2012 | Investigative Ophthalmology and Visual Science

Age-related rarefaction in the fractal dimension of retinal vessel

Mohd Zulfaezal Che Azemin, Dinesh Kant Kumar, Tien Y Wong, Jie Jin Wang, Paul Mitchell, Ryo Kawasaki, Henry Wu

Journal article | 2012 | Neurobiology of Aging

Automatic detection of the macula in retinal fundus images using seeded mode tracking approach.

Damon WK Wong, Jiang Liu, Ngan-Meng Tan, Fengshou Yin, Xiangang Cheng, Ching-Yu Cheng, Gemmy CM Cheung, Tien Yin Wong

Journal article | 2012 | 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

The macula is the part of the eye responsible for central high acuity vision. Detection of the macula is an important task in reti..

Microvascular Dilatation after Haemodialysis Is Determined by the Volume of Fluid Removed and Fall in Mean Arterial Pressure

Foong Kien Newk-Fon Hey Tow, Qi Lun Ooi, Tien Y Wong, Ryo Kawasaki, Deb Colville, Peter Mount, Judy Savige

Journal article | 2012 | Kidney & Blood Pressure Research

Age-related macular degeneration

LS Lim, P Mitchell, JM Seddon, FG Holz, TY Wong

Journal article | 2012 | The Lancet

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

Yoon Shin Cho, Chien-Hsiun Chen, Cheng Hu, Jirong Long, Rick Twee Hee Ong, Xueling Sim, Fumihiko Takeuchi, Ying Wu, Min Jin Go, Toshimasa Yamauchi, Yi-Cheng Chang, Soo Heon Kwak, Ronald CW Ma, Ken Yamamoto, Linda S Adair, Tin Aung, Qiuyin Cai, Li-Ching Chang, Yuan-Tsong Chen, Yutang Gao, et al.

Journal article | 2012 | Nature Genetics

Ranibizumab and bevacizumab for AMD

CMG Cheung, TY Wong

Journal article | 2011 | New England Journal of Medicine

Is Bilateral Age-related Macular Degeneration Less Common in Asians than Caucasians?

Ryo Kawasaki, Jie Jin Wang, FM Amirul Amirul, Elena Rochtchina, Tin Aung, Seang Mei Saw, Paul Mitchell, Tien Yin Wong

Journal article | 2011 | Ophthalmic Epidemiology

SgD-CNV, a database for common and rare copy number variants in three Asian populations

Haiyan Xu, Wan-Ting Poh, Xueling Sim, Rick Twee-Hee Ong, Chen Suo, Wan-Ting Tay, Chiea-Chuen Khor, Mark Seielstad, Jianjun Liu, Tin Aung, E-Shyong Tai, Tien-Yin Wong, Kee-Seng Chia, Yik-Ying Teo

Journal article | 2011 | Human Mutation

Retinal Vessel Caliber and Myopic Retinopathy: The Blue Mountains Eye Study

Haitao Li, Paul Mitchell, Elena Rochtchina, George Burlutsky, Tien Y Wong, Jie Jin Wang

Journal article | 2011 | Ophthalmic Epidemiology

The Prevalence and Risk Factors of Ocular Trauma: The Singapore Indian Eye Study

Daniel Chua, Wanling Wong, Ecosse L Lamoureux, Tin Aung, Seang-Mei Saw, Tien Y Wong

Journal article | 2011 | Ophthalmic Epidemiology

Relationship of Ocular Biometry and Retinal Vascular Caliber in Preschoolers

Ling-Jun Li, Carol Yim-Lui Cheung, Gus Gazzard, Lan Chang, Paul Mitchell, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease

Chiea Chuen Khor, Sonia Davila, Willemijn B Breunis, Yi-Ching Lee, Chisato Shimizu, Victoria J Wright, Rae SM Yeung, Dennis EK Tan, Kar Seng Sim, Jie Jin Wang, Tien Yin Wong, Junxiong Pang, Paul Mitchell, Rolando Cimaz, Nagib Dahdah, Yiu-Fai Cheung, Guo-Ying Huang, Wanling Yang, In-Sook Park, Jong-Keuk Lee, et al.

Journal article | 2011 | Nature Genetics

Prevalence and Characteristics of Choroidal Nevi: The Multi-Ethnic Study of Atherosclerosis

Max B Greenstein, Chelsea E Myers, Stacy M Meuer, Barbara EK Klein, Mary Frances Cotch, Tien Y Wong, Ronald Klein

Journal article | 2011 | Ophthalmology

Determinants of Quantitative Optic Nerve Measurements Using Spectral Domain Optical Coherence Tomography in a Population-Based Sample of Non-glaucomatous Subjects

Carol Y Cheung, David Chen, Tien Y Wong, Yih Chung Tham, Renyi Wu, Yingfeng Zheng, Ching Yu Cheng, Seang Mei Saw, Mani Baskaran, Christopher K Leung, Tin Aung

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies PDGFRA as a Susceptibility Locus for Corneal Astigmatism

Qiao Fan, Xin Zhou, Chiea-Chuen Khor, Ching-Yu Cheng, Liang-Kee Goh, Xueling Sim, Wan-Ting Tay, Yi-Ju Li, Rick Twee-Hee Ong, Chen Suo, Belinda Cornes, Mohammad Kamran Ikram, Kee-Seng Chia, Mark Seielstad, Jianjun Liu, Eranga Vithana, Terri L Young, E-Shyong Tai, Tien-Yin Wong, Tin Aung, et al.

Journal article | 2011 | PLoS Genetics

Retinal arteriolar caliber and urine albumin excretion: the Multi-Ethnic Study of Atherosclerosis

Stella Awua-Larbi, Tien Y Wong, Mary Frances Cotch, Ramon Durazo-Arvizu, David R Jacobs, Barbara EK Klein, Ronald Klein, Joao Lima, Kiang Liu, Holly Kramer

Journal article | 2011 | Nephrology, Dialysis, Transplantation

Hypertension, Hypertension Control, and Chronic Kidney Disease in a Malay Population in Singapore

Charumathi Sabanayagam, Anoop Shankar, Su Chi Lim, E Shyong Tai, Tien Yin Wong

Journal article | 2011 | Asia-Pacific Journal of Public Health

Corneal Arcus is a Sign of Cardiovascular Disease, Even in Low-Risk Persons

Marcus Ang, Wanling Wong, Judy Park, Renyi Wu, Raghavan Lavanya, Yingfeng Zheng, Howard Cajucom-Uy, E Shyong Tai, Tien Yin Wong

Journal article | 2011 | American Journal of Ophthalmology

Differential association of retinal arteriolar and venular caliber with diabetes and retinopathy

Andrew SH Tsai, Tien Yin Wong, Raghavan Lavanya, Rongli Zhang, Haslina Hamzah, E Shyong Tai, Carol Y Cheung

Journal article | 2011 | Diabetes Research and Clinical Practice

Independent Impact of Area-Level Socioeconomic Measures on Visual Impairment

Yingfeng Zheng, Ecosse Lamoureux, Eric Finkelstein, Renyi Wu, Raghavan Lavanya, Daniel Chua, Tin Aung, Seang-Mei Saw, Tien Y Wong

Journal article | 2011 | Investigative Ophthalmology and Visual Science

A 32 kb Critical Region Excluding Y402H in CFH Mediates Risk for Age-Related Macular Degeneration

Theru A Sivakumaran, Robert P Igo, Jeffrey M Kidd, Andy Itsara, Laura J Kopplin, Wei Chen, Stephanie A Hagstrom, Neal S Peachey, Peter J Francis, Michael L Klein, Emily Y Chew, Vedam L Ramprasad, Wan-Ting Tay, Paul Mitchell, Mark Seielstad, Dwight E Stambolian, Albert O Edwards, Kristine E Lee, Dmitry V Leontiev, Gyungah Jun, et al.

Journal article | 2011 | PLoS One

Change in Peripheral Refraction over Time in Singapore Chinese Children

Chelvin CA Sng, Xiao-Yu Lin, Gus Gazzard, Benjamin Chang, Mohamed Dirani, Laurence Lim, Prabakaran Selvaraj, Kit Ian, Bjorn Drobe, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Prevalence and risk factors for refractive errors and ocular biometry parameters in an elderly Asian population: the Singapore Longitudinal Aging Study (SLAS)

CSH Tan, YH Chan, TY Wong, G Gazzard, M Niti, T-P Ng, SM Saw

Journal article | 2011 | Eye - London

Myopia-Related Optic Disc and Retinal Changes in Adolescent Children from Singapore

Chameen Samarawickrama, Paul Mitchell, Louis Tong, Gus Gazzard, Laurence Lim, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2011 | Ophthalmology

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

Jaspal S Kooner, Danish Saleheen, Xueling Sim, Joban Sehmi, Weihua Zhang, Philippe Frossard, Latonya F Been, Kee-Seng Chia, Antigone S Dimas, Neelam Hassanali, Tazeen Jafar, Jeremy BM Jowett, Xinzhong Li, Venkatesan Radha, Simon D Rees, Fumihiko Takeuchi, Robin Young, Tin Aung, Abdul Basit, Manickam Chidambaram, et al.

Journal article | 2011 | Nature Genetics

Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore

Siyu Han, Peng Chen, Qiao Fan, Chiea-Chuen Khor, Xueling Sim, Wan-Ting Tay, Rick Twee-Hee Ong, Chen Suo, Liang-Kee Goh, Raghavan Lavanya, Yingfeng Zheng, Renyi Wu, Mark Seielstad, Eranga Vithana, Jianjun Liu, Kee-Seng Chia, Jeannette Jen-Mai Lee, E-Shyong Tai, Tien-Yin Wong, Tin Aung, et al.

Journal article | 2011 | Human Molecular Genetics

Fluvastatin Downregulates VEGF-A Expression in TNF-alpha-Induced Retinal Vessel Tortuosity

Remya Robinson, Candice EH Ho, Queenie SW Tan, Chi D Luu, Kyaw T Moe, Carol Y Cheung, Tien Y Wong, Veluchamy A Barathi

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Literacy Is an Independent Risk Factor for Vision Impairment and Poor Visual Functioning

Yingfeng Zheng, Ecosse L Lamoureux, Peggy Pei-Chia Chiang, Ching-Yu Cheng, Ainur Rahman Anuar, Seang-Mei Saw, Tin Aung, Tien Yin Wong

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Similarities and differences in early retinal phenotypes in hypertension and diabetes

Andrea Grosso, Ning Cheung, Franco Veglio, Tien Yin Wong

Journal article | 2011 | Journal of Hypertension

Candidate Gene Association Study for Diabetic Retinopathy in Persons with Type 2 Diabetes: The Candidate Gene Association Resource (CARe)

Lucia Sobrin, Todd Green, Xueling Sim, Richard A Jensen, E Shyong Tai, Wan Ting Tay, Jie Jin Wang, Paul Mitchell, Niina Sandholm, Yiyuan Liu, Kustaa Hietala, Sudha K Iyengar, Matthew Brooks, Monika Buraczynska, Natalie Van Zuydam, Albert V Smith, Vilmundur Gudnason, Alex SF Doney, Andrew D Morris, Graham P Leese, et al.

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Prevalence and Characteristics of Myopic Retinopathy in a Rural Chinese Adult Population The Handan Eye Study

Li Qin Gao, Wu Liu, Yuan Bo Liang, Feng Zhang, Jie Jin Wang, Yi Peng, Tien Yin Wong, Ning Li Wang, Paul Mitchell, David S Friedman

Journal article | 2011 | Archives of Ophthalmology

Differential Association of Serum Lipids with Diabetic Retinopathy and Diabetic Macular Edema

Rehab Benarous, Muhammad B Sasongko, Salmaan Qureshi, Eva Fenwick, Mohamed Dirani, Tien Y Wong, Ecosse L Lamoureux

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Prevalence and Causes of Visual Impairment and Blindness in an Urban Indian Population: The Singapore Indian Eye Study

Yingfeng Zheng, Raghavan Lavanya, Renyi Wu, Wan-Ling Wong, Jie Jin Wang, Paul Mitchell, Ning Cheung, Howard Cajucom-Uy, Ecosse Lamoureux, Tin Aung, Seang-Mei Saw, Tien Y Wong

Journal article | 2011 | Ophthalmology

Racial Differences in the Prevalence of Diabetes but Not Diabetic Retinopathy in a Multi-ethnic Asian Population

Peggy PC Chiang, Ecosse L Lamoureux, Carol Y Cheung, Charumathi Sabanayagam, Wanling Wong, E Shyong Tai, Jeannette Lee, Tien Y Wong

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Emerging evidence concerning systemic safety of anti-VEGF agents--should ophthalmologists be concerned?

Laurence S Lim, Chui Ming Gemmy Cheung, Paul Mitchell, Tien Y Wong

Journal article | 2011 | American Journal of Ophthalmology

Parental History of Hypertension Is Associated With Narrower Retinal Arteriolar Caliber in Young Girls

Bamini Gopinath, Louise A Baur, Louise L Hardy, Jie Jin Wang, Erdahl Teber, Tien Y Wong, Paul Mitchell

Journal article | 2011 | Hypertension

Retinal vascular tortuosity in persons with diabetes and diabetic retinopathy

MB Sasongko, TY Wong, TT Nguyen, CY Cheung, JE Shaw, JJ Wang

Journal article | 2011 | Diabetologia

Ocular biometry in an urban Indian population: the Singapore Indian Eye Study (SINDI).

Chen-Wei Pan, Tien-Yin Wong, Lan Chang, Xiao-Yu Lin, Raghavan Lavanya, Ying-Feng Zheng, Yee-Onn Kok, Ren-Yi Wu, Tin Aung, Seang-Mei Saw

Journal article | 2011 | Investigative Ophthalmology and Visual Science

PURPOSE. To describe the distribution and determinants of ocular biometric parameters in adult Singapore Indians. METHODS. A popul..

Associations of Physical Activity and Television Viewing Time with Retinal Vascular Caliber in a Multiethnic Asian Population

Satyamurthy Anuradha, Genevieve N Healy, David W Dunstan, E Shyong Tai, Rob M Van Dam, Jeannette Lee, Ei Ei Khaing Nang, Neville Owen, Tien-Yin Wong

Journal article | 2011 | Investigative Ophthalmology and Visual Science

The relationship of body fatness indices and retinal vascular caliber in children

Ling-Jun Li, Carol Yim-Lui Cheung, Audrey Chia, Prabakaran Selvaraj, Xiao-Yu Lin, Paul Mitchell, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2011 | International Journal of Pediatric Obesity

Retinal microvascular changes and subsequent vascular events after ischemic stroke

DA De Silva, JJF Manzano, EY Liu, F-P Woon, W-X Wong, H-M Chang, C Chen, RI Lindley, JJ Wang, P Mitchell, T-Y Wong, M-C Wong

Journal article | 2011 | Neurology

Ten-Year Longitudinal Changes in Retinal Microvascular Lesions The Atherosclerosis Risk in Communities Study

Gerald Liew, Stephen Campbell, Ronald Klein, Barbara EK Klein, A Richey Sharrett, Mary Frances Cotch, Jie Jin Wang, Tien Y Wong

Journal article | 2011 | Ophthalmology

Prevalence and Risk Factors for Visual Impairment in Preschool Children The Sydney Paediatric Eye Disease Study

Amy Shih-I Pai, Jie Jin Wang, Chameen Samarawickrama, George Burlutsky, Kathryn A Rose, Rohit Varma, Tien Yin Wong, Paul Mitchell

Journal article | 2011 | Ophthalmology

The Microvasculature in Chronic Kidney Disease

Qi Lun Ooi, Foong Kien Newk-Fon Hey Tow, Raj Deva, Mohamad Afzal Alias, Ryo Kawasaki, Tien Y Wong, Nor Mohamad, Deb Colville, Anastasia Hutchinson, Judy Savige

Journal article | 2011 | Clinical Journal of the American Society of Nephrology

Cataract Prevalence Varies Substantially with Assessment Systems: Comparison of Clinical and Photographic Grading in a Population-Based Study

Anna CS Tan, Jie Jin Wang, Ecosse L Lamoureux, Wanling Wong, Paul Mitchell, Jialiang Li, Ava Grace Tan, Tien Y Wong

Journal article | 2011 | Ophthalmic Epidemiology

Fibrate use in the United States and Canada.

Alexander Tenenbaum, Enrique Z Fisman

Journal article | 2011 | JAMA: Journal of the American Medical Association

Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark

Carol Y Cheung, Ce Zheng, Ching-Lin Ho, Tin A Tun, Rajesh S Kumar, Fouad El Sayyad, Tien Y Wong, Tin Aung

Journal article | 2011 | British Journal of Ophthalmology

Quantitative and qualitative retinal microvascular characteristics and blood pressure

Carol Y Cheung, Wan T Tay, Paul Mitchell, Jie J Wang, Wynne Hsu, Mong L Lee, Qiangfeng P Lau, Ai L Zhu, Ronald Klein, Seang M Saw, Tien Y Wong

Journal article | 2011 | Journal of Hypertension

Retinal Arteriolar Narrowing and Subsequent Development of CKD Stage 3: The Multi-Ethnic Study of Atherosclerosis (MESA)

Joanne Wen Yee Yau, Jing Xie, Ryo Kawasaki, Holly Kramer, Michael Shlipak, Ronald Klein, Barbara Klein, Mary Frances Cotch, Tien Yin Wong

Journal article | 2011 | American Journal of Kidney Diseases

Prevalence of Age-Related Macular Degeneration in a Rural Chinese Population: The Handan Eye Study

Ke Yang, Yuan Bo Liang, Li Qin Gao, Yi Peng, Ran Shen, Xin Rong Duan, David S Friedman, Lan Ping Sun, Paul Mitchell, Ning Li Wang, Tien Yin Wong, Jie Jin Wang

Journal article | 2011 | Ophthalmology

Influence of refractive error on optic disc topographic parameters: the singapore malay eye study.

Ren-Yi Wu, Tien-Yin Wong, Ying-Feng Zheng, Carol Yim-Lui Cheung, Shamira A Perera, Seang Mei Saw, Tin Aung

Journal article | 2011 | American Journal of Ophthalmology

PURPOSE: To examine the relationship between refractive error and optic disc topographic parameters and retinal nerve fiber layer ..

Influence of Blood Pressure on Retinal Vascular Caliber in Young Children

Ling-Jun Li, Carol Yim-Lui Cheung, Yang Liu, Audrey Chia, Prabakaran Selvaraj, Xiao-Yu Lin, Yam-Meng Chan, Rohit Varma, Paul Mitchell, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2011 | Ophthalmology

Retinal Arteriolar Wall Signs and Early Age-Related Macular Degeneration: The Singapore Malay Eye Study

Chui Ming Gemmy Cheung, Carol Yim-Lui Cheung, Erica Liu Yang, Paul Mitchell, Jie Jin Wang, Tien Yin Wong

Journal article | 2011 | American Journal of Ophthalmology

Determinants of Corneal Biomechanical Properties in an Adult Chinese Population

Arun Narayanaswamy, Ronald S Chung, Ren-Yi Wu, Judy Park, Wan-Ling Wong, Seang-Mei Saw, Tien Y Wong, Tin Aung

Journal article | 2011 | Ophthalmology

Retinal Vascular Geometry Predicts Incident Retinopathy in Young People With Type 1 Diabetes A prospective cohort study from adolescence

Paul Benitez-Aguirre, Maria E Craig, Muhammad Bayu Sasongko, Alicia J Jenkins, Tien Yin Wong, Jie Jin Wang, Ning Cheung, Kim C Donaghue

Journal article | 2011 | Diabetes Care

Bevacizumab for retinopathy of prematurity.

Laurence S Lim, Paul Mitchell, Tien Y Wong

Journal article | 2011 | New England Journal of Medicine

Effect of obesity on retinal vascular structure in pre-adolescent children

Bamini Gopinath, Louise A Baur, Erdahl Teber, Gerald Liew, Tien Y Wong, Paul Mitchell

Journal article | 2011 | International Journal of Pediatric Obesity

Risk factors for diabetic retinopathy in a rural Chinese population with type 2 diabetes: the Handan Eye Study

Feng Hua Wang, Yuan Bo Liang, Xiao Yan Peng, Jie Jin Wang, Feng Zhang, Wen Bin Wei, Lan Ping Sun, David S Friedman, Ning Li Wang, Tien Yin Wong

Journal article | 2011 | Acta Ophthalmologica (Print)

Are Obesity and Anthropometry Risk Factors for Diabetic Retinopathy?: The Diabetes Management Project

Mohamed Dirani, Jing Xie, Eva Fenwick, Rehab Benarous, Gwyneth Rees, Tien Yin Wong, Ecosse L Lamoureux

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

Norihiro Kato, Fumihiko Takeuchi, Yasuharu Tabara, Tanika N Kelly, Min Jin Go, Xueling Sim, Wan Ting Tay, Chien-Hsiun Chen, Yi Zhang, Ken Yamamoto, Tomohiro Katsuya, Mitsuhiro Yokota, Young Jin Kim, Rick Twee Hee Ong, Toru Nabika, Dongfeng Gu, Li-Ching Chang, Yoshihiro Kokubo, Wei Huang, Keizo Ohnaka, et al.

Journal article | 2011 | Nature Genetics

The impact of diabetic retinopathy: understanding the patient's perspective

EK Fenwick, K Pesudovs, G Rees, M Dirani, R Kawasaki, TY Wong, EL Lamoureux

Journal article | 2011 | British Journal of Ophthalmology

Diabetic Retinopathy Is Related to Both Endothelium-Dependent and -Independent Responses of Skin Microvascular Flow

Thanh T Nguyen, Jonathan E Shaw, Carol Robinson, Ryo Kawasaki, Jie Jin Wang, Andreas J Kreis, Tien Y Wong

Journal article | 2011 | Diabetes Care

Association of Narrow Angles With Anterior Chamber Area and Volume Measured With Anterior-Segment Optical Coherence Tomography

Ren-Yi Wu, Monisha E Nongpiur, Ming-Guang He, Lisandro M Sakata, David S Friedman, Yiong-Huak Chan, Raghavan Lavanya, Tien-Yin Wong, Tin Aung

Journal article | 2011 | Archives of Ophthalmology

FRACTAL DIMENSION OF THE RETINAL VASCULATURE AND RISK OF STROKE: A NESTED CASE-CONTROLSTUDY

R Kawasaki, MZ Che Azemin, DK Kumar, AG Tan, G Liew, TY Wong, P Mitchell, JJ Wang

Journal article | 2011 | Neurology

Impact of early and late age-related macular degeneration on vision-specific functioning

Ecosse L Lamoureux, Paul Mitchell, Gwyn Rees, Gemmy Cheung, Ian Yeo, Shu Yen Lee, Erica Liu, Tien Y Wong

Journal article | 2011 | British Journal of Ophthalmology

Relationship of Smoking and Cardiovascular Risk Factors with Polypoidal Choroidal Vasculopathy and Age-related Macular Degeneration in Chinese Persons

Peter Cackett, Ian Yeo, Chui Ming Gemmy Cheung, Eranga N Vithana, Doric Wong, Wan Ting Tay, E Shyong Tai, Tin Aung, Tien Y Wong

Journal article | 2011 | Ophthalmology

Retinal Vascular Tortuosity, Blood Pressure, and Cardiovascular Risk Factors

Carol Yim-lui Cheung, Yingfeng Zheng, Wynne Hsu, Mong Li Lee, Qiangfeng Peter Lau, Paul Mitchell, Jie Jin Wang, Ronald Klein, Tien Yin Wong

Journal article | 2011 | Ophthalmology

Intravitreal Triamcinolone Prior to Laser Treatment of Diabetic Macular Edema 24-Month Results of a Randomized Controlled Trial

Mark C Gillies, Ian L McAllister, Meidong Zhu, Wanling Wong, Damien Louis, Jennifer J Arnold, Tien Y Wong

Journal article | 2011 | Ophthalmology

Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area

Chiea Chuen Khor, Wishal D Ramdas, Eranga N Vithana, Belinda K Cornes, Xueling Sim, Wan-Ting Tay, Seang-Mei Saw, Yingfeng Zheng, Raghavan Lavanya, Renyi Wu, Jie Jin Wang, Paul Mitchell, Andre G Uitterlinden, Fernando Rivadeneira, Yik-Ying Teo, Kee-Seng Chia, Mark Seielstad, Martin Hibberd, Johannes R Vingerling, Caroline CW Klaver, et al.

Journal article | 2011 | Human Molecular Genetics

Is Diabetic Retinopathy Related to Subclinical Cardiovascular Disease?

Ryo Kawasaki, Ning Cheung, FM Amirul Islam, Ronald Klein, Barbara EK Klein, Mary Frances Cotch, A Richey Sharrett, Daniel O'Leary, Tien Y Wong

Journal article | 2011 | Ophthalmology

Prevalence and Risk Factors for Refractive Errors in Indians: The Singapore Indian Eye Study (SINDI)

Chen-Wei Pan, Tien-Yin Wong, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Xiao-Yu Lin, Paul Mitchell, Tin Aung, Seang-Mei Saw

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Influence of Physical Activity and Screen Time on the Retinal Microvasculature in Young Children

Bamini Gopinath, Louise A Baur, Jie Jin Wang, Louise L Hardy, Erdahl Teber, Annette Kifley, Tien Y Wong, Paul Mitchell

Journal article | 2011 | Arteriosclerosis Thrombosis and Vascular Biology

Retinal vascular calibre is altered in patients with rheumatoid arthritis: a biomarker of disease activity and cardiovascular risk?

Sharon Van Doornum, Gemma Strickland, Ryo Kawasaki, Jing Xie, Ian P Wicks, Lauren AB Hodgson, Tien Y Wong

Journal article | 2011 | Rheumatology

The Use of HRT With and Without the Aid of Disc Photographs

Seng Chee Loon, Louis Tong, Gus Gazzard, Yiong Huak Chan, Ee Ling Sim, Tin Aung, Donald TH Tan, PR Healey, Tien Yin Wong, Victor Koh, Seang Mei Saw

Journal article | 2011 | Journal of Glaucoma

Determinants of Image Quality of Heidelberg Retina Tomography II and its Association With Optic Disc Parameters in a Population-Based Setting

Yingfeng Zheng, Carol Y Cheung, Tien Y Wong, Wanling Wong, Seng-Chee Loon, Tin Aung

Journal article | 2011 | American Journal of Ophthalmology

Emerging therapeutic approaches in the management of retinal angiogenesis and edema

Truong An, Tien Y Wong, Levon M Khachigian

Journal article | 2011 | Journal of Molecular Medicine

Serum C-reactive protein level and prediabetes in two Asian populations

C Sabanayagam, A Shankar, SC Lim, J Lee, ES Tai, TY Wong

Journal article | 2011 | Diabetologia

Comparison of Ocular Response Analyzer Parameters in Chinese Subjects With Primary Angle-Closure and Primary Open-Angle Glaucoma

Arun Narayanaswamy, Daniel H Su, Mani Baskaran, Anna CS Tan, Monisha E Nongpiur, Hla M Htoon, Tien Y Wong, Tin Aung

Journal article | 2011 | Archives of Ophthalmology

Vascular risk factors in glaucoma: a review

Masahide Yanagi, Ryo Kawasaki, Jie Jin Wang, Tien Y Wong, Jonathan Crowston Franzco, Yoshiaki Kiuchi

Journal article | 2011 | Clinical and Experimental Ophthalmology

Metabolic Syndrome Components and Age-Related Cataract: The Singapore Malay Eye Study

Charumathi Sabanayagam, Jie Jin Wang, Paul Mitchell, Ava Grace Tan, E Shyong Tai, Tin Aung, Seang-Mei Saw, Tien Yin Wong

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Retinopathy Signs in People without Diabetes The Multi-Ethnic Study of Atherosclerosis

Elvis Ojaimi, Thanh T Nguyen, Ronald Klein, FM Amirul Islam, Mary Frances Cotch, Barbara EK Klein, Jie-Jin Wang, Tien Yin Wong

Journal article | 2011 | Ophthalmology

Prevalence and Risk Factors for Epiretinal Membranes in a Multi-Ethnic United States Population

Ching Hui Ng, Ning Cheung, Jie Jin Wang, Amirul FM Islam, Ryo Kawasaki, Stacy M Meuer, Mary Frances Cotch, Barbara EK Klein, Ronald Klein, Tien Yin Wong

Journal article | 2011 | Ophthalmology

Distribution of ankle-brachial index and the risk factors of peripheral artery disease in a multi-ethnic Asian population

Tavintharan Subramaniam, Ei Ei Khaing Nang, Su Chi Lim, Yi Wu, Chin Meng Khoo, Jeannette Lee, Derrick Heng, Suok Kai Chew, Tien Y Wong, E Shyong Tai

Journal article | 2011 | Vascular Medicine: the international journal of research review and clinical practice

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia

Xueling Sim, Rick Twee-Hee Ong, Chen Suo, Wan-Ting Tay, Jianjun Liu, Daniel Peng-Keat Ng, Michael Boehnke, Kee-Seng Chia, Tien-Yin Wong, Mark Seielstad, Yik-Ying Teo, E-Shyong Tai

Journal article | 2011 | PLoS Genetics

Relationship of central corneal thickness with optic disc parameters: the Singapore Malay Eye Study.

Ren-Yi Wu, Ying-Feng Zheng, Tien-Yin Wong, Carol Yim-Lui Cheung, Seng-Chee Loon, Balwantray C Chauhan, Tin Aung

Journal article | 2011 | Investigative Ophthalmology and Visual Science

PURPOSE: To examine the relationship of central corneal thickness (CCT) with optic disc parameters measured by confocal scanning l..

The Heritability and Sibling Risk of Angle Closure in Asians

Nishani Amerasinghe, Jian Zhang, Anbupalam Thalamuthu, Mingguang He, Eranga N Vithana, Ananth Viswanathan, Tien Y Wong, Paul J Foster, Tin Aung

Journal article | 2011 | Ophthalmology

Associations of Retinal Microvascular Signs and Intracranial Large Artery Disease

Deidre A De Silva, Jennifer JF Manzano, Fung-Peng Woon, Erica Yang Liu, Moi-Pin Lee, Hui-Yee Gan, Christopher PLH Chen, Hui-Meng Chang, Paul Mitchell, Jie Jin Wang, Richard I Lindley, Tien-Yin Wong, Meng-Cheong Wong

Journal article | 2011 | Stroke

Validity of a New Computer-Aided Diagnosis Imaging Program to Quantify Nuclear Cataract from Slit-lamp Photographs

Carol Yim-lui Cheung, Huiqi Li, Ecosse L Lamoureux, Paul Mitchell, Jie Jin Wang, Ava Grace Tan, Lily K Johari, Jiang Liu, Joo Hwee Lim, Tin Aung, Tien Yin Wong

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Lens Vault, Thickness, and Position in Chinese Subjects with Angle Closure

Monisha E Nongpiur, Mingguang He, Nishani Amerasinghe, David S Friedman, Wan-Ting Tay, Mani Baskaran, Scott D Smith, Tien Yin Wong, Tin Aung

Journal article | 2011 | Ophthalmology

Physical Activity, Television Viewing Time, and Retinal Microvascular Caliber

Satyamurthy Anuradha, Genevieve N Healy, David W Dunstan, Ronald Klein, Barbara E Klein, Mary Frances Cotch, Tien Y Wong, Neville Owen

Journal article | 2011 | American Journal of Epidemiology

Collagen-related genes influence the glaucoma risk factor, central corneal thickness

Eranga N Vithana, Tin Aung, Chiea Chuen Khor, Belinda K Cornes, Wan-Ting Tay, Xueling Sim, Raghavan Lavanya, Renyi Wu, Yingfeng Zheng, Martin L Hibberd, Kee Seng Chia, Mark Seielstad, Liang Kee Goh, Seang-Mei Saw, E Shyong Tai, Tien Y Wong

Journal article | 2011 | Human Molecular Genetics

Prevalence and Causes of Amblyopia in a Rural Adult Population of Chinese The Handan Eye Study

Yue Wang, Yuan Bo Liang, Lan Ping Sun, Xin Rong Duan, Rui Zhi Yuan, Tien Yin Wong, Peng Yi, David S Friedman, Ning Li Wang, Jie Jin Wang

Journal article | 2011 | Ophthalmology

Transient Ischemic Attack and Acute Ischemic Stroke Associations With Retinal Microvascular Signs

Jie Jin Wang, Michelle L Baker, Peter J Hand, Graeme J Hankey, Richard I Lindley, Elena Rochtchina, Tien Y Wong, Gerald Liew, Paul Mitchell

Journal article | 2011 | Stroke

Influence of Refractive Error and Axial Length on Retinal Vessel Geometric Characteristics

Laurence Shen Lim, Carol Yim-Lui Cheung, Xiaoyu Lin, Paul Mitchell, Tien Yin Wong, Seang Mei-Saw

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Serum Apolipoprotein AI and B Are Stronger Biomarkers of Diabetic Retinopathy Than Traditional Lipids

Muhammad Bayu Sasongko, Tien Y Wong, Thanh T Nguyen, Ryo Kawasaki, Alicia Jenkins, Jonathan Shaw, Jie Jin Wang

Journal article | 2011 | Diabetes Care

Fractal analysis of retinal microvasculature and coronary heart disease mortality

Gerald Liew, Paul Mitchell, Elena Rochtchina, Tien Yin Wong, Wynne Hsu, Mong Li Lee, Alan Wainwright, Jie Jin Wang

Journal article | 2011 | European Heart Journal

Genome-Wide Association Studies Reveal Genetic Variants in CTNND2 for High Myopia in Singapore Chinese

Yi-Ju Li, Liang Goh, Chiea-Chuen Khor, Qiao Fan, Miao Yu, Siyu Han, Xueling Sim, Rick Twee-Hee Ong, Tien-Yin Wong, Eranga Nishanthie Vithana, Eric Yap, Hideo Nakanishi, Fumihiko Matsuda, Kyoko Ohno-Matsui, Nagahisa Yoshimura, Mark Seielstad, E-Shyong Tai, Terri L Young, Seang-Mei Saw

Journal article | 2011 | Ophthalmology

Peripheral Refraction and Refractive Error in Singapore Chinese Children

Chelvin CA Sng, Xiao-Yu Lin, Gus Gazzard, Benjamin Chang, Mohamed Dirani, Audrey Chia, Prabakaran Selvaraj, Kit Ian, Bjorn Drobe, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Are Lung Disease and Function Related to Age-Related Macular Degeneration?

Sonia Moorthy, Ning Cheung, Ronald Klein, Eyal Shahar, Tien Y Wong

Journal article | 2011 | American Journal of Ophthalmology

The Relationship between Retinal Arteriolar and Venular Calibers Is Genetically Mediated, and Each Is Associated with Risk of Cardiovascular Disease

Samantha J Fahy, Cong Sun, Gu Zhu, Paul R Healey, Tim D Spector, Nicolas G Martin, Paul Mitchell, Tien Y Wong, David A Mackey, Christopher J Hammond, Toby Andrew

Journal article | 2011 | Investigative Ophthalmology and Visual Science

Robust Methodology for Fractal Analysis of the Retinal Vasculature

MZ Che Azemin, DK Kumar, TY Wong, R Kawasaki, P Mitchell, JJ Wang

Journal article | 2011 | IEEE TRANSACTIONS ON MEDICAL IMAGING

Physical Activity, Television Viewing Time, and Retinal Vascular Caliber

Satyamurthy Anuradha, David W Dunstan, Genevieve N Healy, Jonathan E Shaw, Paul Z Zimmet, Tien Y Wong, Neville Owen

Journal article | 2011 | Medicine and Science in Sports and Exercise

Retinal Image Matching Using Hierarchical Vascular Features

Alauddin Bhuiyan, Ecosse Lamoureux, Baikunth Nath, Kotagiri Ramamohanarao, Tien Y Wong

Journal article | 2011 | Computational Intelligence and Neuroscience

Retinal vessel diameter as a clinical predictor of diabetic retinopathy progression: time to take out the measuring tape.

Tien Yin Wong

Journal article | 2011 | Archives of Ophthalmology

A computer assisted method for nuclear cataract grading from slit-lamp images using ranking.

Wei Huang, Kap Luk Chan, Huiqi Li, Joo Hwee Lim, Jiang Liu, Tien Yin Wong

Journal article | 2011 | IEEE TRANSACTIONS ON MEDICAL IMAGING

In clinical diagnosis, a grade indicating the severity of nuclear cataract is often manually assigned by a trained ophthalmologist..

Automatic detection of cortical and PSC cataracts using texture and intensity analysis on retro-illumination lens images.

Yew Chung Chow, Xinting Gao, Huiqi Li, Joo Hwee Lim, Ying Sun, Tien Yin Wong

Journal article | 2011 | 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Cataract remains a leading cause for blindness worldwide. Cataract diagnosis via human grading is subjective and time-consuming. S..

A NEW AND EFFICIENT VESSEL SEGMENTATION METHOD FROM COLOR RETINAL IMAGES

Alauddin Bhuiyan, Ryo Kawasaki, Ecosse Lamoureux, Kotagiri Ramamohanarao, Tien Y Wong

Conference Proceedings | 2011 | Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing (BIOSIGNALS)

Glycated Hemoglobin and the Risk of Kidney Disease and Retinopathy in Adults With and Without Diabetes

Elizabeth Selvin, Yang Ning, Michael W Steffes, Lori D Bash, Ronald Klein, Tien Y Wong, Brad C Astor, A Richey Sharrett, Frederick L Brancati, Josef Coresh

Journal article | 2011 | Diabetes

Glycemic Thresholds for Diabetes-Specific Retinopathy Implications for diagnostic criteria for diabetes

Stephen Colagiuri, Crystal MY Lee, Tien Y Wong, Beverley Balkau, Jonathan E Shaw, Knut Borch-Johnsen

Journal article | 2011 | Diabetes Care

Retinal-vein occlusion - author reply

TY Wong, IU Scott

Journal article | 2011 | New England Journal of Medicine

Toll-Like Receptor 3 Polymorphism rs3775291 Is Not Associated with Choroidal Neovascularization or Polypoidal Choroidal Vasculopathy in Chinese Subjects

Chelvin CA Sng, Peter D Cackett, Ian Y Yeo, Anbupalam Thalamuthu, Anandalakshmi Venkatraman, Divya Venkataraman, Adrian H Koh, E-Shyong Tai, Tien Y Wong, Tin Aung, Eranga N Vithana

Journal article | 2011 | Ophthalmic Research: journal for research in experimental and clinical ophthalmology

Multi-ethnic study of atherosclerosis. Is diabetic retinopathy related to subclinical cardiovascular disease?: Author reply

R Kawasaki, TY Wong

Journal article | 2011 | Ophthalmology

AN AUTOMATED METHOD FOR RETINAL IMAGE MATCHING USING VASCULAR FEATURES

Alauddin Bhuiyan, Baikunth Nath, Kotagiri Ramamohanarao, Tien Y Wong

Conference Proceedings | 2011 | Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing (BIOSIGNALS)

Diabetic retinopathy and cardiovascular disease: Author reply

R Kawasaki, TY Wong

Journal article | 2011 | Ophthalmology

Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis

Usha Chakravarthy, Tien Y Wong, Astrid Fletcher, Elisabeth Piault, Christopher Evans, Gergana Zlateva, Ronald Buggage, Andreas Pleil, Paul Mitchell

Journal article | 2010 | BMC Ophthalmology

Vessel segmentation from color retinal images with varying contrast and central reflex properties

A Bhuiyan, R Kawasaki, E Lamoureux, TY Wong, K Ramamohanarao

Conference Proceedings | 2010 | 2010 International Conference on Digital Image Computing: Techniques and Applications

Author Response: Model-Fitting Adequacy and Clinical Rationality in Multivariate Linear Regression Analysis

Laurence Shen Lim, Tien Yin Wong

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Prevalence and causes of decreased visual acuity in Singaporean Chinese preschoolers

M Dirani, B Zhou, D Hornbeak, BC Chang, G Gazzard, A Chia, Y Ling, P Selvaraj, TL Young, R Varma, TY Wong, SM Saw

Journal article | 2010 | British Journal of Ophthalmology

Hyperopic Refractive Error and Shorter Axial Length Are Associated with Age-Related Macular Degeneration: The Singapore Malay Eye Study

Raghavan Lavanya, Ryo Kawasaki, Wan Ting Tay, Gemmy CM Cheung, Paul Mitchell, Seang-Mei Saw, Tin Aung, Tien Y Wong

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Retinal vascular features for cardio vascular disease prediction: A review

A Bhuiyan, R Kawasaki, E Lamoureux, TY Wong, K Ramamohanarao

Journal article | 2010 | Recent Patents on Computer Science

Retinal-Vein Occlusion.

Tien Y Wong, Ingrid U Scott

Journal article | 2010 | New England Journal of Medicine

Vitrectomy for diabetic macular edema.

Ning Cheung, Paul Connell, Tien Y Wong

Journal article | 2010 | Ophthalmology

Influence of Diabetes and Diabetic Retinopathy on the Performance of Heidelberg Retina Tomography II for Diagnosis of Glaucoma

Yingfeng Zheng, Tien Y Wong, Carol Yim-Lui Cheung, Ecosse Lamoureux, Paul Mitchell, Mingguang He, Tin Aung

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Is the Pediatric Quality of Life Inventory Valid for Use in Preschool Children with Refractive Errors?

Ecosse L Lamoureux, Manjula Marella, Benjamin Chang, Mohamed Dirani, Au Eong Kah-Guan, Audrey Chia, Terry L Young, Tien Y Wong, Seang Mei Saw

Journal article | 2010 | Optometry and Vision Science

Effect of Image Quality, Color, and Format on the Measurement of Retinal Vascular Fractal Dimension

Alan Wainwright, Gerald Liew, George Burlutsky, Elena Rochtchina, Yong Ping Zhang, Wynne Hsu, Janice MongLi Lee, Tien Yin Wong, Paul Mitchell, Jie Jin Wang

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Cardiovascular Risk Factors, Inflammation, and Corneal Arcus: The Singapore Malay Eye Study

Reny Wu, Jie Jin Wang, E Shyong Tai, Tien Yin Wong

Journal article | 2010 | American Journal of Ophthalmology

Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo

M Kamran Ikram, Sim Xueling, Richard A Jensen, Mary Frances Cotch, Alex W Hewitt, M Arfan Ikram, Jie Jin Wang, Ronald Klein, Barbara EK Klein, Monique MB Breteler, Ning Cheung, Gerald Liew, Paul Mitchell, Andre G Uitterlinden, Fernando Rivadeneira, Albert Hofman, Paulus TVM de Jong, Cornelia M van Duijn, Linda Kao, Ching-Yu Cheng, et al.

Journal article | 2010 | PLoS Genetics

Mixed messages on systemic therapies for diabetic retinopathy

Laurence Shen Lim, Gerald Liew, Ning Cheung, Paul Mitchell, Tien Y Wong

Journal article | 2010 | The Lancet

Retinopathy and Lobar Intracerebral Hemorrhage Insights Into Pathogenesis

Michelle L Baker, Peter J Hand, Tien Y Wong, Gerald Liew, Elena Rochtchina, Paul Mitchell, Richard I Lindley, Graeme J Hankey, Jie Jin Wang

Journal article | 2010 | Archives of Neurology

Automated Layer Segmentation of Optical Coherence Tomography Images

Shijian Lu, Carol Yim-lui Cheung, Jiang Liu, Joo Hwee Lim, Christopher Kai-shun Leung, Tien Yin Wong

Journal article | 2010 | IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Novel Association of Smaller Anterior Chamber Width with Angle Closure in Singaporeans

Monisha E Nongpiur, Lisandro M Sakata, David S Friedman, Mingguang He, Yiong-Huak Chan, Raghavan Lavanya, Tien Yin Wong, Tin Aung

Journal article | 2010 | Ophthalmology

Differential Associations of Cortical and Subcortical Cerebral Atrophy With Retinal Vascular Signs in Patients With Acute Stroke

Michelle L Baker, Jie Jin Wang, Gerald Liew, Peter J Hand, Deidre A De Silva, Richard I Lindley, Paul Mitchell, Meng-Cheong Wong, Elena Rochtchina, Tien Y Wong, Joanna M Wardlaw, Graeme J Hankey

Journal article | 2010 | Stroke

A New Method to Measure Peripheral Retinal Vascular Caliber over an Extended Area

Carol Yim-Lui Cheung, Wynne Hsu, Mong Li Lee, Jie Jin Wang, Paul Mitchell, Qiangfeng Peter Lau, Haslina Hamzah, Maisie Ho, Tien Yin Wong

Journal article | 2010 | Microcirculation

Diagnostic accuracy of the Heidelberg Retina Tomograph for glaucoma a population-based assessment.

Paul R Healey, Anne J Lee, Tin Aung, Tien Y Wong, Paul Mitchell

Journal article | 2010 | Ophthalmology

OBJECTIVE: To evaluate the Heidelberg Retina Tomograph II (HRTII; Heidelberg Engineering, Heidelberg, Germany) as a screening tool..

Retinal fractal dimension is increased in persons with diabetes but not impaired glucose metabolism: the Australian Diabetes, Obesity and Lifestyle (AusDiab) study

JWY Yau, R Kawasaki, FMA Islam, J Shaw, P Zimmet, JJ Wang, TY Wong

Journal article | 2010 | Diabetologia

C-reactive Protein, Body Mass Index, and Diabetic Retinopathy

Laurence Shen Lim, E Shyong Tai, Paul Mitchell, Jie Jin Wang, Wan Ting Tay, Ecosse Lamoureux, Tien Yin Wong

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Influence of OCT Signal Strength on Macular, Optic Nerve Head, and Retinal Nerve Fiber Layer Parameters

Chameen Samarawickrama, Amy Pai, Son C Huynh, George Burlutsky, Tien Y Wong, Paul Mitchell

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Impact of symptomatic dry eye on vision-related daily activities: The Singapore Malay Eye Study

L Tong, S Waduthantri, TY Wong, SM Saw, JJ Wang, M Rosman, E Lamoureux

Journal article | 2010 | Eye

Glycemic and Blood Pressure Control in an Asian Malay Population With Diabetes and Diabetic Retinopathy

Olivia S Huang, Ecosse L Lamoureux, Wan Ting Tay, E Shyong Tai, Jie Jin Wang, Tien Y Wong

Journal article | 2010 | Archives of Ophthalmology

Retinal Vascular Fractal Dimension Measurement and Its Influence from Imaging Variation: Results of Two Segmentation Methods

Victoria Fay Cosatto, Gerald Liew, Elena Rochtchina, Alan Wainwright, YongPing Zhang, Wynne Hsu, Mong Li Lee, Qiangfeng Peter Lau, Haslina H Hamzah, Paul Mitchell, Tien Yin Wong, Jie Jin Wang

Journal article | 2010 | Current Eye Research

Lens opacity and refractive influences on the measurement of retinal vascular fractal dimension

Haitao Li, Paul Mitchell, Gerald Liew, Elena Rochtchina, Annette Kifley, Tien Y Wong, Wynne Hsu, Mong L Lee, Yong P Zhang, Jie J Wang

Journal article | 2010 | Acta Ophthalmologica (Print)

Biological, clinical and population relevance of 95 loci for blood lipids

Tanya M Teslovich, Kiran Musunuru, Albert V Smith, Andrew C Edmondson, Ioannis M Stylianou, Masahiro Koseki, James P Pirruccello, Samuli Ripatti, Daniel I Chasman, Cristen J Willer, Christopher T Johansen, Sigrid W Fouchier, Aaron Isaacs, Gina M Peloso, Maja Barbalic, Sally L Ricketts, Joshua C Bis, Yurii S Aulchenko, Gudmar Thorleifsson, Mary F Feitosa, et al.

Journal article | 2010 | Nature

Family history, near work, outdoor activity, and myopia in Singapore Chinese preschool children

Wilson Low, Mohamed Dirani, Gus Gazzard, Yiong-Huak Chan, Hui-Jun Zhou, Prabakaran Selvaraj, Kah-Guan Au Eong, Terri L Young, Paul Mitchell, Tien-Yin Wong, Seang-Mei Saw

Journal article | 2010 | British Journal of Ophthalmology

Smoking, Socioeconomic Factors, and Age-Related Cataract

Renyi Wu, Jie Jin Wang, Paul Mitchell, Ecosse L Lamoureux, Yingfeng Zheng, Elena Rochtchina, Ava G Tan, Tien Yin Wong

Journal article | 2010 | Archives of Ophthalmology

Retinal Microvascular Signs and 10-Year Risk of Cerebral Atrophy The Atherosclerosis Risk in Communities (ARIC) Study

Ryo Kawasaki, Ning Cheung, Thomas Mosley, Amirul FM Islam, A Richey Sharrett, Ronald Klein, Laura H Coker, David S Knopman, Dean K Shibata, Diane Catellier, Tien Y Wong

Journal article | 2010 | Stroke

Ethnic disparities in prevalence and impact of risk factors of chronic kidney disease

Charumathi Sabanayagam, Su Chi Lim, Tien Yin Wong, Jeannette Lee, Anoop Shankar, E Shyong Tai

Journal article | 2010 | Nephrology, Dialysis, Transplantation

The prevalence of and risk factors for pterygium in an urban Malay population: The Singapore Malay Eye Study (SiMES)

H Cajucom-Uy, L Tong, TY Wong, WT Tay, SM Saw

Journal article | 2010 | British Journal of Ophthalmology

Triamcinolone-induced cataract in eyes with diabetic macular oedema: 3-year prospective data from a randomized clinical trial

Mark C Gillies, Fakir MA Islam, Jorgen Larsson, Sirichi Pasadhika, Chris Gaston, Meidong Zhu, Tien Y Wong

Journal article | 2010 | Clinical and Experimental Ophthalmology

Normal Macular Thickness Measurements Using Optical Coherence Tomography in Healthy Eyes of Adult Chinese Persons: The Handan Eye Study

Xin Rong Duan, Yuan Bo Liang, David S Friedman, Lan Ping Sun, Tien Yin Wong, Qiu Shan Tao, Lingzhi Bao, Ning Li Wang, Jie Jin Wang

Journal article | 2010 | Ophthalmology

Diabetic retinopathy

Ning Cheung, Paul Mitchell, Tien Yin Wong

Journal article | 2010 | The Lancet

Evidence of Early Retinal Microvascular Changes in Patients With Type 2 Diabetes and Depression

Thanh Tan Nguyen, Tien Y Wong, FM Amirul Islam, Larry Hubbard, Olusola Ajilore, Ebrahim Haroon, Christine Darwin, Barbara Esser, Anand Kumar

Journal article | 2010 | Psychosomatic Medicine

Blood pressure is associated with retinal vessel signs in preadolescent children

Bamini Gopinath, Louise A Baur, Jie J Wang, Erdahl Teber, Gerald Liew, Ning Cheung, Tien Y Wong, Paul Mitchell

Journal article | 2010 | Journal of Hypertension

Retinal Vascular Caliber and Brachial Flow-Mediated Dilation The Multi-Ethnic Study of Atherosclerosis

Thanh T Nguyen, FM Amirul Islam, HM Omar Farouque, Ronald Klein, Barbara EK Klein, Mary Frances Cotch, David M Herrington, Tien Yin Wong

Journal article | 2010 | Stroke

Relationship of Retinal Vascular Tortuosity with the Neuroretinal Rim: The Singapore Malay Eye Study

Victor Koh, Carol Yim-lui Cheung, Yingfeng Zheng, Tien Yin Wong, Wanling Wong, Tin Aung

Journal article | 2010 | Investigative Ophthalmology and Visual Science

Fractal analysis of the retinal vasculature and chronic kidney disease

Chelvin CA Sng, Charumathi Sabanayagam, Ecosse L Lamoureux, Erica Liu, Su Chi Lim, Haslina Hamzah, Jeannette Lee, E Shyong Tai, Tien Y Wong

Journal article | 2010 | Nephrology, Dialysis, Transplantation

Retinal Vascular Fractals and Microvascular and Macrovascular Complications in Type 1 Diabetes

Jakob Grauslund, Anders Green, Ryo Kawasaki, Lauren Hodgson, Anne Katrin Sjolie, Tien Y Wong

Journal article | 2010 | Ophthalmology

Prof

Tien Wong

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Ophthalmology Eye And Ear Hospital

Prof

Tien Wong

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Medicine, Dentistry And Health Sciences

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Retinal vascular diseases - Ophthalmology

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Tien Wong

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FEATURED Journal article

Computerized adaptive tests: Efficient and precise assessment of the patient-centered impact of diabetic retinopathy

Tien Wong's selected work

Research Contracts

Journal article

Research Grant

Journal article

Research Grant

Journal article

Projects

Cra - Retinal Vascular Research

NHMRC Research Fellowship

Asia Pacific Grading Workshop 2008

Retinal Microvascular Signs And Cvd In Older Persons

Early Retinal Vessel Changes In Diabetes And The Metabolic Syndrome

5

Projects

Project Types

Scholarly Works

Computerized adaptive tests: Efficient and precise assessment of the patient-centered impact of diabetic retinopathy

Association of alcohol intake with incidence and progression of diabetic retinopathy.

Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections

Cardiovascular health and retinal microvascular geometry in Australian 11-12 year-olds

Associations of Retinal Vessel Caliber With Hearing Status in Childhood and Midlife A Cross-Generational Population-Based Study

Inflammation mediates the relationship between obesity and retinal vascular calibre in 11-12 year-olds children and mid-life adults.

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Validation of a novel diabetic retinopathy utility index using discrete choice experiments

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

Genetic architecture of subcortical brain structures in 38,851 individuals

Natural history of diabetic macular edema and factors predicting outcomes in sham-treated patients (MEAD study)

Associations of retinal microvascular caliber with intermediate phenotypes of large arterial function and structure: A systematic review and meta-analysis

Health-related behaviours in a remote Indigenous population with Type 2 diabetes: a Central Australian primary care survey in the Telehealth Eye and Associated Medical Services Network [TEAMSnet] project

Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population.

Child Health CheckPoint: cohort summary and methodology of a physical health and biospecimen module for the Longitudinal Study of Australian Children

Retinal microvasculature: population epidemiology and concordance in Australian children aged 11-12 years and their parents

Prevalence and causes of blindness and vision impairment: magnitude, temporal trends and projections in South and Central Asia

Prevalence and causes of vision loss in Latin America and the Caribbean in 2015: magnitude, temporal trends and projections

A Multi-Country Study of Myopia in Children: Digital Data Capture Using an Innovative Application - plano

Prevalence and causes of vision loss in South-east Asia and Oceania in 2015: magnitude, temporal trends and projections

Prevalence and causes of vision loss in North Africa and Middle East in 2015: magnitude, temporal trends and projections

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Microvascular narrowing and BP monitoring: A single centre observational study

Myopia - A 21st Century Public Health Issue

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (vol 9, 1864, 2018)

From reading books to increased smart device screen time

Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders

An Automated Grading System for Detection of Vision-Threatening Referable Diabetic Retinopathy on the Basis of Color Fundus Photographs

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017

The Relationship between Generalized and Abdominal Obesity with Diabetic Kidney Disease in Type 2 Diabetes: A Multiethnic Asian Study and Meta-Analysis

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes

Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study

Guidelines on Diabetic Eye Care The International Council of Ophthalmology Recommendations for Screening, Follow-up, Referral, and Treatment Based on Resource Settings

Age-related macular degeneration

Association of serum lutein and zeaxanthin with quantitative measures of retinal vascular parameters

Diet soft drink is associated with increased odds of proliferative diabetic retinopathy

Impact of Incidence and Progression of Diabetic Retinopathy on Vision-Specific Functioning

A novel model of persistent retinal neovascularization for the development of sustained anti-VEGF therapies

Macro- and Microvascular Parameters After Toxic Shock Syndrome

Reply.

Retinal Arteriolar Narrowing in Young Adults With Glaucomatous Optic Disc

Age-related macular degeneration and progression of coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis