Tien Wong

Risk of Normal Tension Glaucoma Progression From Automated Baseline Retinal-Vessel Caliber Analysis: A Prospective Cohort Study.

Timothy PH Lin, Herbert YH Hui, Annie Ling, Poemen P Chan, Ruyue Shen, Mandy OM Wong, Noel CY Chan, Dexter YL Leung, Dejiang Xu, Mong Li Lee, Wynne Hsu, Tien Yin Wong, Clement C Tham, Carol Y Cheung

Journal article  |  2023  |  Am J Ophthalmol

PURPOSE: To determine the relationship between baseline retinal-vessel calibers computed by a deep-learning system and the risk of..

Relationship between vision impairment and employment.

Yi Xuen Chai, Alfred Tau Liang Gan, Eva K Fenwick, Abraham Y Sui, Benjamin Kye Jyn Tan, Debra QY Quek, Chaoxu Qian, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux, Ryan Eyn Kidd Man

Journal article  |  2023  |  Br J Ophthalmol

AIMS: To examine the relationship between vision impairment (VI) and employment outcomes in a multiethnic Asian population. METHOD..

Six-year incidence of age-related macular degeneration and correlation to OCT-derived drusen volume measurements in a Chinese population.

Anna Cs Tan, Miao Li Chee, Beau J Fenner, Paul Mitchell, Yih Chung Tham, Tyler Rim, Kelvin Teo, Shaun S Sim, Ching Yu Cheng, Tien Yin Wong, Usha Chakravarthy, Chui Ming Gemmy Cheung

Journal article  |  2023  |  Br J Ophthalmol

AIMS: To report the 6-year incidence of optical coherence tomography (OCT)-derived age-related changes in drusen volume and relate..

Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration.

Levon M Khachigian, Gerald Liew, Kelvin YC Teo, Tien Y Wong, Paul Mitchell

Journal article  |  2023  |  J Transl Med

Neovascular age-related macular degeneration (nAMD) is a major cause of visual impairment and blindness. Anti-vascular endothelial..

Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness.

Beau J Fenner, Hengtong Li, Alfred TL Gan, Young Seok Song, Yih Chung Tham, Jost B Jonas, Ya Xing Wang, Ching Yu Cheng, Tien Yin Wong, Kelvin YC Teo, Anna CS Tan, Qiao Fan, Chui Ming Gemmy Cheung

Journal article  |  2023  |  Invest Ophthalmol Vis Sci

PURPOSE: To identify genetic alleles associated with differences in choroidal thickness (CT) in a population-based multiethnic Asi..

PATTERN AND CHARACTERISTICS OF DRUSEN SUBTYPES IN CHINESE AND INDIAN POPULATIONS IN SINGAPORE.

Kengo Takahashi, Youngseok Song, Kai Xiong Cheong, Beau J Fenner, Kelvin Yi Chong Teo, Miao Li Chee, Hengtong Li, Yih-Chung Tham, Chui Ming Gemmy Cheung, Ching-Yu Cheng, Tien Yin Wong, Yasuo Yanagi, Anna CS Tan

Journal article  |  2023  |  Retina

PURPOSE: To report the pattern and characteristics of drusen subtypes in Asian populations and the association with choroidal thic..

The Singapore National Precision Medicine Strategy.

Eleanor Wong, Nicolas Bertin, Maxime Hebrard, Roberto Tirado-Magallanes, Claire Bellis, Weng Khong Lim, Chee Yong Chua, Philomena Mei Lin Tong, Raymond Chua, Kenneth Mak, Tit Meng Lim, Wei Yang Cheong, Kwee Eng Thien, Khean Teik Goh, Jin-Fang Chai, Jimmy Lee, Joseph Jao-Yiu Sung, Tien Yin Wong, Calvin Woon Loong Chin, Peter D Gluckman, et al.

Journal article  |  2023  |  Nat Genet

Precision medicine promises to transform healthcare for groups and individuals through early disease detection, refining diagnoses..

The management of neovascular age-related macular degeneration: A systematic literature review of patient-reported outcomes, patient mental health and caregiver burden.

Richard P Gale, Robert P Finger, Bora Eldem, Tariq Aslam, Jane Barratt, Vincent Daien, Laurent Kodjikian, Anat Loewenstein, Mali Okada, Tien Yin Wong, Michelle Sylvanowicz, Francisco J Rodríguez

Journal article  |  2023  |  Acta Ophthalmol

PURPOSE: The aim of this systematic literature review was to describe patient-reported outcomes, mental health and caregiver burde..

Deep learning system to predict the 5-year risk of high myopia using fundus imaging in children.

Li Lian Foo, Gilbert Yong San Lim, Carla Lanca, Chee Wai Wong, Quan V Hoang, Xiu Juan Zhang, Jason C Yam, Leopold Schmetterer, Audrey Chia, Tien Yin Wong, Daniel SW Ting, Seang-Mei Saw, Marcus Ang

Journal article  |  2023  |  NPJ Digit Med

Our study aims to identify children at risk of developing high myopia for timely assessment and intervention, preventing myopia pr..

Validation of a deep-learning-based retinal biomarker (Reti-CVD) in the prediction of cardiovascular disease: data from UK Biobank.

Rachel Marjorie Wei Wen Tseng, Tyler Hyungtaek Rim, Eduard Shantsila, Joseph K Yi, Sungha Park, Sung Soo Kim, Chan Joo Lee, Sahil Thakur, Simon Nusinovici, Qingsheng Peng, Hyeonmin Kim, Geunyoung Lee, Marco Yu, Yih-Chung Tham, Ameet Bakhai, Paul Leeson, Gregory YH Lip, Tien Yin Wong, Ching-Yu Cheng

Journal article  |  2023  |  BMC Med

BACKGROUND: Currently in the United Kingdom, cardiovascular disease (CVD) risk assessment is based on the QRISK3 score, in which 1..