Tien Wong

Repositioning of the global epicentre of non-optimal cholesterol

Cristina Taddei, Bin Zhou, Honor Bixby, Rodrigo M Carrillo-Larco, Goodarz Danaei, Rod T Jackson, Farshad Farzadfar, Marisa K Sophiea, Mariachiara Di Cesare, Maria Laura Caminia Iurilli, Andrea Rodriguez Martinez, Golaleh Asghari, Klodian Dhana, Pablo Gulayin, Sujay Kakarmath, Marilina Santero, Trudy Voortman, Leanne M Riley, Melanie J Cowan, Stefan Savin, et al.

Journal article  |  2020  |  Nature

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determi..

Using a smart device-based application to capture big data on eye care utilization in children across 8 countries

Joshua Foreman, Arief Tjitra Salim, Dwight Fonseka, Marcus Ang, Audrey Chia, Tien Yin Wong, Jonathan Guy Crowston, Mohamed Dirani

Conference Proceedings  |  2020  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Computerized Adaptive Tests: Efficient and Precise Assessment of the Patient-Centered Impact of Diabetic Retinopathy.

Eva K Fenwick, John Barnard, Alfred Gan, Bao Sheng Loe, Jyoti Khadka, Konrad Pesudovs, Ryan Man, Shu Yen Lee, Gavin Tan, Tien Y Wong, Ecosse L Lamoureux

Journal article  |  2020  |  Translational Vision Science and Technology

Purpose: Evaluate efficiency, precision, and validity of RetCAT, which comprises ten diabetic retinopathy (DR) quality of life (Qo..

Association of alcohol intake with incidence and progression of diabetic retinopathy.

Preeti Gupta, Eva K Fenwick, Charumathi Sabanayagam, Alfred Tau Liang Gan, Yih-Chung Tham, Sahil Thakur, Ryan Eyn Kidd Man, Paul Mitchell, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux

Journal article  |  2020  |  British Journal of Ophthalmology

PURPOSE: We examined the longitudinal association of baseline alcohol intake and frequency with the 6-year incidence and progressi..

Do body mass index and waist-to-height ratio over the preceding decade predict retinal microvasculature in 11-12 year olds and midlife adults?

Mengjiao Liu, Kate Lycett, Tien Yin Wong, Jessica A Kerr, Mingguang He, Markus Juonala, Tim Olds, Terry Dwyer, David Burgner, Melissa Wake

Journal article  |  2020  |  International Journal of Obesity

BACKGROUND/OBJECTIVES: Microvascular changes may contribute to obesity-associated cardiovascular disease. We examined whether body..

Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections

Ching-Yu Cheng, Ningli Wang, Tien Y Wong, Nathan Congdon, Mingguang He, Ya Xing Wang, Tasanee Braithwaite, Robert J Casson, Maria Vittoria Cicinelli, Aditi Das, Seth R Flaxman, Jost B Jonas, Jill Elizabeth Keeffe, John H Kempen, Janet Leasher, Hans Limburg, Kovin Naidoo, Konrad Pesudovs, Serge Resnikoff, Alexander J Silvester, et al.

Journal article  |  2020  |  British Journal of Ophthalmology

BACKGROUND: To determine the prevalence and causes of blindness and vision impairment (VI) in East Asia in 2015 and to forecast th..

Cardiovascular health and retinal microvascular geometry in Australian 11-12 year-olds

Mengjiao Liu, Kate Lycett, Melissa Wake, Mingguang He, Jessica A Kerr, Richard Saffery, Markus Juonala, Tim Olds, Terry Dwyer, David P Burgner, Tien Yin Wong

Journal article  |  2020  |  Microvascular Research

Traditional retinal microvascular parameters (smaller arteriolar and greater venular caliber) are associated with cardiovascular r..

Associations of Retinal Vessel Caliber With Hearing Status in Childhood and Midlife A Cross-Generational Population-Based Study

Jing Wang, Mengjiao Liu, Valerie Sung, Kate Lycett, Anneke Grobler, David Burgner, Tien Yin Wong, Melissa Wake

Journal article  |  2020  |  JAMA Otolaryngology - Head & Neck Surgery

Importance: Microvascular phenotypes, which can be assessed using retinal imaging, may be informative about the life course pathog..

Inflammation mediates the relationship between obesity and retinal vascular calibre in 11-12 year-olds children and mid-life adults

Mengjiao Liu, Kate Lycett, Margarita Moreno-Betancur, Tien Yin Wong, Mingguang He, Richard Saffery, Markus Juonala, Jessica A Kerr, Melissa Wake, David P Burgner

Journal article  |  2020  |  Scientific Reports

Obesity predicts adverse microvasculature from childhood, potentially via inflammatory pathways. We investigated whether inflammat..

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Qiao Fan, Alfred Pozarickij, Nicholas YQ Tan, Xiaobo Guo, Virginie JM Verhoeven, Veronique Vitart, Jeremy A Guggenheim, Masahiro Miyake, J Willem L Tideman, Anthony P Khawaja, Liang Zhang, Stuart MacGregor, Rene Hoehn, Peng Chen, Ginevra Biino, Juho Wedenoja, Seyed Ehsan Saffari, Milly S Tedja, Jing Xie, Carla Lanca, et al.

Journal article  |  2020  |  Communications Biology

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and b..