Keng Chew

The impact of influenza pulmonary infection and inflammation on vagal bronchopulmonary sensory neurons

Nathalie AJ Verzele, Brendon Y Chua, Charity W Law, Albert Zhang, Matthew E Ritchie, Oliver Wightman, Isaac N Edwards, Katina D Hulme, Conor J Bloxham, Helle Bielefeldt-Ohmann, Matthew W Trewella, Aung Aung Kywe Moe, Keng Yih Chew, Stuart B Mazzone, Kirsty R Short, Alice E McGovern

Journal article  |  2021  |  FASEB JOURNAL

Influenza A virus (IAV) is rapidly detected in the airways by the immune system, with resident parenchymal cells and leukocytes or..

Expression of STRA8 is conserved in therian mammals but expression of CYP26B1 differs between marsupials and mice

Danielle E Hickford, Siew Fen Lisa Wong, Stephen R Frankenberg, Geoff Shaw, Hongshi Yu, Keng Yih Chew, Marilyn B Renfree

Journal article  |  2017  |  BIOLOGY OF REPRODUCTION

The first sign of mammalian germ cell sexual differentiation is the initiation of meiosis in females and of mitotic arrest in male..

Inducing Sex Reversal in Marsupial Mammals

Keng Y Chew, Marilyn B Renfree

Journal article  |  2016  |  SEXUAL DEVELOPMENT

Marsupials are born with undifferentiated gonads, and their reproductive organs differentiate consecutively, not simultaneously as..

FOXA1 and SOX9 Expression in the Developing Urogenital Sinus of the Tammar Wallaby (Macropus eugenii)

Melissa Gamat, Keng Yih Chew, Geoffrey Shaw, Marilyn B Renfree

Journal article  |  2015  |  SEXUAL DEVELOPMENT

The mammalian prostate is a compact structure in humans but multi-lobed in mice. In humans and mice, FOXA1 and SOX9 play pivotal r..

Antibodies Mediate Formation of Neutrophil Extracellular Traps in the Middle Ear and Facilitate Secondary Pneumococcal Otitis Media

Kirsty R Short, Maren von Koeckritz-Blickwede, Jeroen D Langereis, Keng Yih Chew, Emma R Job, Charles W Armitage, Brandon Hatcher, Kohtaro Fujihashi, Patrick C Reading, Peter W Hermans, Odilia L Wijburg, Dimitri A Diavatopoulos

Journal article  |  2014  |  INFECTION AND IMMUNITY

Otitis media (OM) (a middle ear infection) is a common childhood illness that can leave some children with permanent hearing loss...

Hormone-Independent Pathways of Sexual Differentiation

Marilyn B Renfree, Keng Yih Chew, Geoffrey Shaw

Journal article  |  2014  |  SEXUAL DEVELOPMENT

New observations over the last 25 years of hormone-independent sexual dimorphisms have gradually and unequivocally overturned the ..

Inducing sex reversal of the urogenital system of marsupials

Marilyn B Renfree, Keng Yih Chew, Geoff Shaw

Journal article  |  2014  |  DIFFERENTIATION

Marsupials differ from eutherian mammals in their reproductive strategy of delivering a highly altricial young after a short gesta..

A Dual Role for SHH during Phallus Development in a Marsupial

KY Chew, AJ Pask, D Hickford, G Shaw, MB Renfree

Journal article  |  2014  |  SEXUAL DEVELOPMENT

The mammalian phallus arises from identical primordia in both sexes and is patterned in part by the key morphogen Sonic hedgehog (..

Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development

Marilyn B Renfree, Anthony T Papenfuss, Janine E Deakin, James Lindsay, Thomas Heider, Katherine Belov, Willem Rens, Paul D Waters, Elizabeth A Pharo, Geoff Shaw, Emily Swwong, Christophe M Lefevre, Kevin R Nicholas, Yoko Kuroki, Matthew J Wakefield, Kyall R Zenger, Chenwei Wang, Malcolm Ferguson-Smith, Frank W Nicholas, Danielle Hickford, et al.

Journal article  |  2011  |  GENOME BIOLOGY

BACKGROUND: We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and t..