Phil Sutton

Method of eliciting or inducing an immune response

J SCHEERLINCK, P SUTTON, S Edwards, M Pearse

Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children.

Melanie R Neeland, Samantha Bannister, Vanessa Clifford, Kate Dohle, Kim Mulholland, Philip Sutton, Nigel Curtis, Andrew C Steer, David P Burgner, Nigel W Crawford, Shidan Tosif, Richard Saffery

Journal article  |  2021  |  Nature Communications

Children have mild severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confirmed disease (COVID-19) compared to adults an..

Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19

Shidan Tosif, Melanie R Neeland, Philip Sutton, Paul V Licciardi, Sohinee Sarkar, Kevin J Selva, Anh Ha Do Lien, Celeste Donato, Zheng Quan Toh, Rachel Higgins, Carolien Van de Sandt, Melissa M Lemke, Christina Y Lee, Suzanne K Shoffner, Katie L Flanagan, Kelly B Arnold, Francesca L Mordant, Kim Mulholland, Julie Bines, Kate Dohle, et al.

Journal article  |  2020  |  Nature Communications

Compared to adults, children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have predominantly mild or asymptom..

Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer

Sharleen Chung Nien Chin, Louise O'Connor, Michelle Scurr, Jonathan T Busada, Alison N Graham, Ghazal Alipour Talesh, Chau P Tran, Sohinee Sarkar, Toshinari Minamoto, Andrew S Giraud, John A Cidlowski, Philip Sutton, Trevelyan R Menheniott

Journal article  |  2020  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

Gastrokines (GKNs) are anti-inflammatory proteins secreted by gastric epithelial (surface mucous and pit) cells, with their aberra..

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response toHelicobacter pyloriInfection in Mice

Yong H Sheng, Garrett Z Ng, Kim M Summers, Alison L Every, Gareth Price, Sumaira Z Hasnain, Philip Sutton, Michael A McGuckin

Journal article  |  2020  |  Frontiers in Cellular and Infection Microbiology

The cell surface mucin MUC1 is an important host factor limiting Helicobacter pylori (H. pylori) pathogenesis in both humans and m..

A lack of role for antibodies in regulating Helicobacter pylori colonization and associated gastritis

Umar Arshad, Sohinee Sarkar, Ghazal Alipour Talesh, Philip Sutton

Journal article  |  2020  |  Helicobacter

BACKGROUND: Helicobacter pylori occupy a unique niche, located within the mucus layer lining the stomach, and attached to the apic..

Understanding COVID-19 in children may provide clues to protect at-risk populations.

Lien Anh Ha Do, Jeremy Anderson, Philip Sutton, Daniel G Pellicci, Kim Mulholland, Paul V Licciardi

Journal article  |  2020  |  BMJ Paediatrics Open

Status of vaccine research and development for Helicobacter pylori

Philip Sutton, Joanne M Boag

Journal article  |  2019  |  Vaccine

Gastric adenocarcinoma is globally the third leading cause of death due to malignancy, with the bulk of this disease burden being ..

Effect of MUC1 length polymorphisms on the NLRP3 inflammasome response of human macrophages

Poshmaal Dhar, Sohinee Sarkar, Garrett Z Ng, Paul Kalitsis, Muhammad A Saeed, Michael A McGuckin, Justine A Ellis, Philip Sutton

Journal article  |  2019  |  Human Immunology

Mucin 1 is a cell-membrane associated mucin, expressed on epithelial and immune cells that helps protect against pathogenic infect..

Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations

Jon N Buzzelli, Louise O'Connor, Michelle Scurr, Sharleen Chung Nien Chin, Angelique Catubig, Garrett Z Ng, Masanobu Oshima, Hiroko Oshima, Andrew S Giraud, Philip Sutton, Louise M Judd, Trevelyan R Menheniott

Journal article  |  2019  |  AJP Gastrointestinal and Liver Physiology

NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells

Le Son Tran, Darren Tran, Amanda De Paoli, Kimberley D'Costa, Sarah J Creed, Garrett Z Ng, Lena Le, Philip Sutton, J Silke, U Nachbur, Richard L Ferrero

Journal article  |  2018  |  Cellular Microbiology