Phil Sutton

A bacterial stimulation assay for bronchoalveolar lavage immune cells from young children with cystic fibrosis

Haipei Liu, Sohinee Sarkar, Kristy Azzopardi, Sophie Day, Serene Yeow, Sarath Ranganathan, Philip Sutton

Journal article  |  2021  |  SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Cystic Fibrosis (CF) is primarily a progressive lung disease, characterized by chronic pulmonary infections with opportunistic pat..

Systems serology detects functionally distinct coronavirus antibody features in children and elderly

Kevin J Selva, Carolien E van de Sandt, Melissa M Lemke, Christina Y Lee, Suzanne K Shoffner, Brendon Y Chua, Samantha K Davis, Thi HO Nguyen, Louise C Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, Francesca Mordant, David C Jackson, Katie L Flanagan, Jane Crowe, Shidan Tosif, Melanie R Neeland, Philip Sutton, Paul Licciardi, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared to children. Examining baseline SARS-CoV-..

Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children

Melanie R Neeland, Samantha Bannister, Vanessa Clifford, Kate Dohle, Kim Mulholland, Philip Sutton, Nigel Curtis, Andrew C Steer, David P Burgner, Nigel W Crawford, Shidan Tosif, Richard Saffery

Journal article  |  2021  |  NATURE COMMUNICATIONS

Children have mild severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confirmed disease (COVID-19) compared to adults an..

Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19

Shidan Tosif, Melanie R Neeland, Philip Sutton, Paul V Licciardi, Sohinee Sarkar, Kevin J Selva, Anh Ha Do Lien, Celeste Donato, Zheng Quan Toh, Rachel Higgins, Carolien Van de Sandt, Melissa M Lemke, Christina Y Lee, Suzanne K Shoffner, Katie L Flanagan, Kelly B Arnold, Francesca L Mordant, Kim Mulholland, Julie Bines, Kate Dohle, et al.

Journal article  |  2020  |  NATURE COMMUNICATIONS

Compared to adults, children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have predominantly mild or asymptom..

Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer

Sharleen Chung Nien Chin, Louise O'Connor, Michelle Scurr, Jonathan T Busada, Alison N Graham, Ghazal Alipour Talesh, Chau P Tran, Sohinee Sarkar, Toshinari Minamoto, Andrew S Giraud, John A Cidlowski, Philip Sutton, Trevelyan R Menheniott

Journal article  |  2020  |  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gastrokines (GKNs) are anti-inflammatory proteins secreted by gastric epithelial (surface mucous and pit) cells, with their aberra..

Immune responses to SARS-CoV-2 in children of parents with symptomatic COVID-19

Shidan Tosif, Melanie Neeland, Philip Sutton, Paul Licciardi, Sohinee Sarkar, Kevin Selva, Lien Anh Ha Do, Celeste Donato, Zheng Quan Toh, Rachel Higgins, Carolien van de Sandt, Melissa Lemke, Christina Lee, Suzanne Shoffner, Katie Flanagan, Kelly Arnold, Francesca Mordant, Kim Mulholland, Julie Bines, Kate Dohle, et al.

Journal article  |  2020

Compared to adults, children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have mild or asymptomatic infection..

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response toHelicobacter pyloriInfection in Mice

Yong H Sheng, Garrett Z Ng, Kim M Summers, Alison L Every, Gareth Price, Sumaira Z Hasnain, Philip Sutton, Michael A McGuckin

Journal article  |  2020  |  FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

The cell surface mucin MUC1 is an important host factor limiting Helicobacter pylori (H. pylori) pathogenesis in both humans and m..

Understanding COVID-19 in children may provide clues to protect at-risk populations

Anh Ha Do Lien, Jeremy Anderson, Philip Sutton, Daniel G Pellicci, Kim Mulholland, Paul V Licciardi

Journal article  |  2020  |  BMJ PAEDIATRICS OPEN

A lack of role for antibodies in regulating Helicobacter pylori colonization and associated gastritis

Umar Arshad, Sohinee Sarkar, Ghazal Alipour Talesh, Philip Sutton

Journal article  |  2020  |  HELICOBACTER

BACKGROUND: Helicobacter pylori occupy a unique niche, located within the mucus layer lining the stomach, and attached to the apic..

Status of vaccine research and development for Helicobacter pylori

Philip Sutton, Joanne M Boag

Journal article  |  2019  |  VACCINE

Gastric adenocarcinoma is globally the third leading cause of death due to malignancy, with the bulk of this disease burden being ..