Vi Nguyen

Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria

Damanpreet Garcha, Susan P Walker, Teresa M MacDonald, Jon Hyett, Jessica Jellins, Jenny Myers, Sebastian E Illanes, Jhy K Nien, Manuel Schepeler, Emerson Keenan, Carole-Anne Whigham, Ping Cannon, Elizabeth Murray, Tuong-Vi Nguyen, Manju Kandel, Joshua Masci, Ciara Murphy, Tess Cruickshank, Natasha Pritchard, Natalie J Hannan, et al.

Journal article  |  2021  |  SCIENTIFIC REPORTS

Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomar..

Placental growth factor is negatively regulated by epidermal growth factor receptor (EGFR) signaling.

Carole-Anne Whigham, Roxanne Hastie, Natalie J Hannan, Fiona Brownfoot, Natasha Pritchard, Ping Cannon, Tuong Vi Nguyen, Manju Kandel, Joshua Masci, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2021  |  Placenta

INTRODUCTION: Preeclampsia is associated with reduced pro-angiogenic Placental Growth Factor (PlGF) and increased levels of anti-a..

Developmental variation in testosterone:cortisol ratio alters cortical- and amygdala-based cognitive processes.

Jimin Lew, Sherri Lee Jones, Christina Caccese, Isobel Orfi, Charlotte Little, Kelly N Botteron, James T McCracken, Tuong-Vi Nguyen

Journal article  |  2021  |  J Dev Orig Health Dis

Testosterone (T) and cortisol (C) are the end products of neuroendocrine axes that interact with the process of shaping brain stru..

Elevated Circulating and Placental SPINT2 Is Associated with Placental Dysfunction

Ciara N Murphy, Susan P Walker, Teresa M MacDonald, Emerson Keenan, Natalie J Hannan, Mary E Wlodek, Jenny Myers, Jessica F Briffa, Tania Romano, Alexandra Roddy Mitchell, Carole-Anne Whigham, Ping Cannon, Tuong-Vi Nguyen, Manju Kandel, Natasha Pritchard, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biomarkers for placental dysfunction are currently lacking. We recently identified SPINT1 as a novel biomarker; SPINT2 is a functi..

Maternal circulating SPINT1 is reduced in small-for-gestational age pregnancies at 26 weeks: Growing up in Singapore towards health outcomes (GUSTO) cohort study

Tu'uhevaha J Kaitu'u-Lino, Stephen Tong, Susan P Walker, Teresa M MacDonald, Ping Cannon, Tuong-Vi Nguyen, Suresh Anand Sadananthan, Mya-Thway Tint, Yi Ying Ong, Loy See Ling, Peter D Gluckman, Yap-Seng Chong, Keith M Godfrey, Shiao-Yng Chan, Kok Hian Tan, Yung Seng Lee, Navin Michael, Johan G Eriksson, Mary E Wlodek

Journal article  |  2021  |  PLACENTA

Fetal growth restriction arising from placental insufficiency is a leading cause of stillbirth. We recently identified low materna..

The NIMH Intramural Longitudinal Study of the Endocrine and Neurobiological Events Accompanying Puberty: Protocol and rationale for methods and measures.

Katherine M Cole, Shau-Ming Wei, Pedro E Martinez, Tuong-Vi Nguyen, Michael D Gregory, J Shane Kippenhan, Philip D Kohn, Steven J Soldin, Lynnette K Nieman, Jack A Yanovski, Peter J Schmidt, Karen F Berman

Journal article  |  2021  |  Neuroimage

Delineating the relationship between human neurodevelopment and the maturation of the hypothalamic-pituitary-gonadal (HPG) axis du..

Pomalidomide, bortezomib, and dexamethasone for multiple myeloma previously treated with lenalidomide (OPTIMISMM): outcomes by prior treatment at first relapse.

Meletios Dimopoulos, Katja Weisel, Philippe Moreau, Larry D Anderson, Darrell White, Jesus San-Miguel, Pieter Sonneveld, Monika Engelhardt, Matthew Jenner, Alessandro Corso, Jan Dürig, Michel Pavic, Morten Salomo, Eva Casal, Shankar Srinivasan, Xin Yu, Tuong Vi Nguyen, Tsvetan Biyukov, Teresa Peluso, Paul Richardson

Journal article  |  2021  |  Leukemia

In the phase 3 OPTIMISMM trial, pomalidomide, bortezomib, and dexamethasone (PVd) demonstrated superior efficacy vs bortezomib and..

Role of testosterone: cortisol ratio in age- and sex-specific cortico-hippocampal development and cognitive performance.

Christina Caccese, Sherri Lee Jones, Mrinalini Ramesh, Ally Yu, Marie Brossard-Racine, Tuong-Vi Nguyen

Journal article  |  2021  |  J Dev Orig Health Dis

Testosterone (T) and cortisol (C) are steroid hormones that have been argued to play opposing roles in shaping physical and behavi..

Processed foods drive intestinal barrier permeability and microvascular diseases.

Matthew Snelson, Sih Min Tan, Rachel E Clarke, Cassandra de Pasquale, Vicki Thallas-Bonke, Tuong-Vi Nguyen, Sally A Penfold, Brooke E Harcourt, Karly C Sourris, Runa S Lindblom, Mark Ziemann, David Steer, Assam El-Osta, Michael J Davies, Leigh Donnellan, Permal Deo, Nicole J Kellow, Mark E Cooper, Trent M Woodruff, Charles R Mackay, et al.

Journal article  |  2021  |  Sci Adv

Intake of processed foods has increased markedly over the past decades, coinciding with increased microvascular diseases such as c..

Pregnancy hypertension and its association with maternal anxiety and mood disorders: A population-based study of 9 million pregnancies.

Jason Raina, Amira El-Messidi, Ahmad Badeghiesh, Togas Tulandi, Tuong-Vi Nguyen, Eva Suarthana

Journal article  |  2021  |  J Affect Disord

BACKGROUND: Evidence on whether anxiety or mood disorders increases the risk of hypertensive disorders of pregnancy (HDP) has been..