Jennifer Stone

Interval breast cancer risk associations with breast density, family history and breast tissue aging

Tuong L Nguyen, Shuai Li, Gillian S Dite, Ye K Aung, Christopher F Evans, Ho N Trinh, Laura Baglietto, Jennifer Stone, Yun-Mi Song, Joohon Sung, Dallas R English, Mark A Jenkins, Pierre-Antoine Dugue, Roger L Milne, Melissa C Southey, Graham G Giles, Malcolm C Pike, John L Hopper

Journal article  |  2019  |  International Journal of Cancer

Interval breast cancers (those diagnosed between recommended mammography screens) generally have poorer outcomes and are more comm..

Genome-wide association study of peripheral blood DNA methylation and conventional mammographic density measures

Shuai Li, Pierre-Antoine Dugue, Laura Baglietto, Gianluca Severi, Ee Ming Wong, Tuong L Nguyen, Jennifer Stone, Dallas R English, Melissa C Southey, Graham G Giles, John L Hopper, Roger L Milne

Journal article  |  2019  |  International Journal of Cancer

Age- and body mass index (BMI)-adjusted mammographic density is one of the strongest breast cancer risk factors. DNA methylation i..

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

Xiang Shu, Lang Wu, Nikhil K Khankari, Xiao-Ou Shu, Thomas J Wang, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Roger L Milne, Marjanka K Schmidt, Paul DP Pharoah, Irene L Andrulis, David J Hunter, Jacques Simard, Douglas F Easton, Wei Zheng, Beeghly-Fadiel J Alicia, Hoda Anton-Culver, Natalia N Antonenkova, et al.

Journal article  |  2019  |  International Journal of Epidemiology

Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circula..

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Manuel A Ferreira, Eric R Gamazon, Fares Al-Ejeh, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Adalgeir Arason, Volker Arndt, Kristan J Aronson, Banu K Arun, Ella Asseryanis, Jacopo Azzollini, Judith Balmana, Daniel R Barnes, Daniel Barrowdale, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Katarzyna Bialkowska, et al.

Journal article  |  2019  |  NATURE COMMUNICATIONS

Inference about causation between body mass index and DNA methylation in blood from a twin family study

Shuai Li, Ee Ming Wong, Minh Bui, Tuong L Nguyen, Ji-Hoon Eric Joo, Jennifer Stone, Gillian S Dite, Pierre-Antoine Dugue, Roger L Milne, Graham G Giles, Richard Saffery, Melissa C Southey, John L Hopper

Journal article  |  2019  |  International Journal of Obesity

Shared heritability and functional enrichment across six solid cancers

Xia Jiang, Hilary K Finucane, Fredrick R Schumacher, Stephanie L Schmit, Jonathan P Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B Kuchenbaecker, Joe Dennis, David V Conti, Graham Casey, Mia M Gaudet, Jeroen R Huyghe, Demetrius Albanes, Melinda C Aldrich, Angeline S Andrew, Irene L Andrulis, Hoda Anton-Culver, Antonis C Antoniou, et al.

Journal article  |  2019  |  NATURE COMMUNICATIONS

Predicting interval and screen-detected breast cancers from mammographic density defined by different brightness thresholds

Tuong L Nguyen, Ye K Aung, Shuai Li, Ho Trinh Nhut, Christopher F Evans, Laura Baglietto, Kavitha Krishnan, Gillian S Dite, Jennifer Stone, Dallas R English, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, John L Hopper

Journal article  |  2018  |  BREAST CANCER RESEARCH

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

Lang Wu, Wei Shi, Jirong Long, Xingyi Guo, Kyriaki Michailidou, Jonathan Beesley, Manjeet K Bolla, Xiao-Ou Shu, Yingchang Lu, Qiuyin Cai, Fares Al-Ejeh, Esdy Rozali, Qin Wang, Joe Dennis, Bingshan Li, Chenjie Zeng, Helian Feng, Alexander Gusev, Richard T Barfield, Irene L Andrulis, et al.

Journal article  |  2018  |  Nature Genetics

Should breast cancer screening programs routinely measure mammographic density?

Jennifer Stone

Journal article  |  2018  |  Journal of Medical Imaging and Radiation Oncology

Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study

Shuai Li, Ee Ming Wong, Minh Bui, Tuong L Nguyen, Ji-Hoon Eric Joo, Jennifer Stone, Gillian S Dite, Graham G Giles, Richard Saffery, Melissa C Southey, John L Hopper

Journal article  |  2018  |  CLINICAL EPIGENETICS

InforMD: a new initiative to raise public awareness about breast density

Honor J Hugo, Aneta Zysk, Pallave Dasari, Kara Britt, John L Hopper, Jennifer Stone, Erik W Thompson, Wendy V Ingman

Journal article  |  2018  |  ecancermedicalscience

Role of breast density measurement in screening for breast cancer

KE McLean, J Stone

Journal article  |  2018  |  Climacteric

Mammographic density and risk of breast cancer by tumor characteristics: a case-control study

Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Catriona McLean, Melissa C Southey, Dallas R English, Graham G Giles, John L Hopper

Journal article  |  2017  |  BMC Cancer

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Roger L Milne, Karoline B Kuchenbaecker, Kyriaki Michailidou, Jonathan Beesley, Siddhartha Kar, Sara Lindstrom, Shirley Hui, Audrey Lemacon, Penny Soucy, Joe Dennis, Xia Jiang, Asha Rostamianfar, Hilary Finucane, Manjeet K Bolla, Lesley McGuffog, Qin Wang, Cora M Aalfs, Marcia Adams, Julian Adlard, Simona Agata, et al.

Journal article  |  2017  |  Nature Genetics

Association analysis identifies 65 new breast cancer risk loci

Kyriaki Michailidou, Sara Lindstrom, Joe Dennis, Jonathan Beesley, Shirley Hui, Siddhartha Kar, Audrey Lemacon, Penny Soucy, Dylan Glubb, Asha Rostamianfar, Manjeet K Bolla, Qin Wang, Jonathan Tyrer, Ed Dicks, Andrew Lee, Zhaoming Wang, Jamie Allen, Renske Keeman, Ursula Eilber, Juliet D French, et al.

Journal article  |  2017  |  Nature

Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide

Anya Burton, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martin Lajous, Ruy Lopez-Ridaura, Megan Rice, Ana Pereira, Maria Luisa Garmendia, Rulla M Tamimi, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Samera A Qureshi, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, et al.

Journal article  |  2017  |  PLOS Medicine

Longitudinal Study of Mammographic Density Measures That Predict Breast Cancer Risk

Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Julie A Simpson, Gianluca Severi, Christopher F Evans, Robert J MacInnis, Graham G Giles, Carmel Apicella, John L Hopper

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

Mammographic density defined by higher than conventional brightness thresholds better predicts breast cancer risk

Tuong L Nguyen, Ye K Aung, Christopher F Evans, Gillian S Dite, Jennifer Stone, Robert J MacInnis, James G Dowty, Adrian Bickerstaffe, Kelly Aujard, Johanna M Rommens, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, Carmel Apicella, John L Hopper

Journal article  |  2017  |  INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Optical pre-screening in breast screening programs: Can we identify women who benefit most from limited mammography resources?

Jane Walter, Maxim Loshchenov, Vladimir Zhilkin, Rachel Peake, Jennifer Stone, Lothar Lilge

Conference Proceedings  |  2017  |  International Conference on Biophotonics V

Mammographic density assessed on paired raw and processed digital images and on paired screen-film and digital images across three mammography systems

Anya Burton, Graham Byrnes, Jennifer Stone, Rulla M Tamimi, John Heine, Celine Vachon, Vahit Ozmen, Ana Pereira, Maria Luisa Garmendia, Christopher Scott, John H Hipwell, Caroline Dickens, Joachim Schuz, Mustafa Erkin Aribal, Kimberly Bertrand, Ava Kwong, Graham G Giles, John Hopper, Beatriz Perez Gomez, Marina Pollan, et al.

Journal article  |  2016  |  BREAST CANCER RESEARCH

Mammographic density and risk of breast cancer by mode of detection and tumor size: a case-control study

Kavitha Krishnan, Laura Baglietto, Carmel Apicella, Jennifer Stone, Melissa C Southey, Dallas R English, Graham G Giles, John L Hopper

Journal article  |  2016  |  BREAST CANCER RESEARCH

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

Alison M Dunning, Kyriaki Michailidou, Karoline B Kuchenbaecker, Deborah Thompson, Juliet D French, Jonathan Beesley, Catherine S Healey, Siddhartha Kar, Karen A Pooley, Elena Lopez-Knowles, Ed Dicks, Daniel Barrowdale, Nicholas A Sinnott-Armstrong, Richard C Sallari, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Mahdi Moradi Marjaneh, Jason S Lee, Margaret Hills, et al.

Journal article  |  2016  |  Nature Genetics

International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries

Valerie A McCormack, Anya Burton, Isabel dos-Santos-Silva, John H Hipwell, Caroline Dickens, Dorria Salem, Rasha Kamal, Mikael Hartman, Charmaine Pei Ling Lee, Kee-Seng Chiah, Vahit Ozmen, Mustafa Erkin Aribal, Anath Arzee Flugelman, Martin Lajous, Ruy Lopez-Riduara, Megan Rice, Isabelle Romieun, Giske Ursin, Samera Qureshi, Huiyan Ma, et al.

Journal article  |  2016  |  Cancer Epidemiology

Childhood body mass index and adult mammographic density measures that predict breast cancer risk

John L Hopper, Tuong L Nguyen, Jennifer Stone, Kelly Aujard, Melanie C Matheson, Michael J Abramson, John A Burgess, E Haydn Walters, Gillian S Dite, Minh Bui, Christopher Evans, Enes Makalic, Daniel F Schmidt, Gail Ward, Mark A Jenkins, Graham G Giles, Shyamali C Dharmage, Carmel Apicella

Journal article  |  2016  |  BREAST CANCER RESEARCH AND TREATMENT

Genetic and Environmental Causes of Variation in the Difference Between Biological Age Based on DNA Methylation and Chronological Age for Middle-Aged Women

Shuai Li, Ee Ming Wong, JiHoon E Joo, Chol-Hee Jung, Jessica Chung, Carmel Apicella, Jennifer Stone, Gillian S Dite, Graham G Giles, Melissa C Southey, John L Hopper

Journal article  |  2015  |  Twin Research and Human Genetics

Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials.

Alex S Willoughby, Gui-Shuang Ying, Cynthia A Toth, Maureen G Maguire, Russell E Burns, Juan E Grunwald, Ebenezer Daniel, Glenn J Jaffe, undefined Comparison of Age-Related Macular Degeneration Treatments Trials Research Group

Journal article  |  2015  |  Ophthalmology

PURPOSE: To evaluate the association of subretinal hyperreflective material (SHRM) with visual acuity (VA), geographic atrophy (GA..

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

Hatef Darabi, Karen Mccue, Jonathan Beesley, Kyriaki Michailidou, Silje Nord, Siddhartha Kar, Keith Humphreys, Deborah Thompson, Maya Ghoussaini, Manjeet K Bolla, Joe Dennis, Qin Wang, Sander Canisius, Christopher G Scott, Carmel Apicella, John L Hopper, Melissa C Southey, Jennifer Stone, Annegien Broeks, Marjanka K Schmidt, et al.

Journal article  |  2015  |  The American Journal of Human Genetics

Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures

Jennifer Stone, Deborah J Thompson, Isabel dos Santos Silva, Christopher Scott, Rulla M Tamimi, Sara Lindstrom, Peter Kraft, Aditi Hazra, Jingmei Li, Louise Eriksson, Kamila Czene, Per Hall, Matt Jensen, Julie Cunningham, Janet E Olson, Kristen Purrington, Fergus J Couch, Judith Brown, Jean Leyland, Ruth ML Warren, et al.

Journal article  |  2015  |  Cancer Research

Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21

Pablo Fernandez-Navarro, Anna Gonzalez-Neira, Guillermo Pita, Ramon Diaz-Uriarte, Leticia Tais Moreno, Maria Ederra, Carmen Pedraz-Pingarron, Carmen Sanchez-Contador, Jose Antonio Vazquez-Carrete, Pilar Moreo, Carmen Vidal, Dolores Salas-Trejo, Jennifer Stone, Melissa C Southey, John L Hopper, Beatriz Perez-Gomez, Javier Benitez, Marina Pollan

Journal article  |  2015  |  International Journal of Cancer

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2

Nick Orr, Frank Dudbridge, Nicola Dryden, Sarah Maguire, Daniela Novo, Eleni Perrakis, Nichola Johnson, Maya Ghoussaini, John L Hopper, Melissa C Southey, Carmel Apicella, Jennifer Stone, Marjanka K Schmidt, Annegien Broeks, Laura J Van't Veer, Frans B Hogervorst, Peter A Fasching, Lothar Haeberle, Arif B Ekici, Matthias W Beckmann, et al.

Journal article  |  2015  |  HUMAN MOLECULAR GENETICS

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

Wei-Yu Lin, Nicola J Camp, Maya Ghoussaini, Jonathan Beesley, Kyriaki Michailidou, John L Hopper, Carmel Apicella, Melissa C Southey, Jennifer Stone, Marjanka K Schmidt, Annegien Broeks, Laura J Van't Veer, Emiel J Th Rutgers, Kenneth Muir, Artitaya Lophatananon, Sarah Stewart-Brown, Pornthep Siriwanarangsan, Peter A Fasching, Lothar Haeberle, Arif B Ekici, et al.

Journal article  |  2015  |  Human Molecular Genetics

MicroRNA Related Polymorphisms and Breast Cancer Risk

Sofia Khan, Dario Greco, Kyriaki Michailidou, Roger L Milne, Taru A Muranen, Tuomas Heikkinen, Kirsimari Aaltonen, Joe Dennis, Manjeet K Bolla, Jianjun Liu, Per Hall, Astrid Irwanto, Keith Humphreys, Jingmei Li, Kamila Czene, Jenny Chang-Claude, Rebecca Hein, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, et al.

Journal article  |  2014  |  PLOS ONE

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

Sara Lindstroem, Deborah J Thompson, Andrew D Paterson, Jingmei Li, Gretchen L Gierach, Christopher Scott, Jennifer Stone, Julie A Douglas, Isabel dos-Santos-Silva, Pablo Fernandez-Navarro, Jajini Verghase, Paula Smith, Judith Brown, Robert Luben, Nicholas J Wareham, Ruth JF Loos, John A Heit, V Shane Pankratz, Aaron Norman, Ellen L Goode, et al.

Journal article  |  2014  |  Nature Communications

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.

Derek W Morris, Richard D Pearson, Paul Cormican, Elaine M Kenny, Colm T O'Dushlaine, Louis-Philippe Lemieux Perreault, Eleni Giannoulatou, Daniela Tropea, Brion S Maher, Brandon Wormley, Eric Kelleher, Ciara Fahey, Ines Molinos, Stefania Bellini, Matti Pirinen, Amy Strange, Colin Freeman, Dawn L Thiselton, Rachel L Elves, Regina Regan, et al.

Journal article  |  2014  |  Human Molecular Genetics

Identifying rare, highly penetrant risk mutations may be an important step in dissecting the molecular etiology of schizophrenia. ..

Mammographic Density Phenotypes and Risk of Breast Cancer: A Meta-analysis

Andreas Pettersson, Rebecca E Graff, Giske Ursin, Isabel dos Santos Silva, Valerie McCormack, Laura Baglietto, Celine Vachon, Marije F Bakker, Graham G Giles, Kee Seng Chia, Kamila Czene, Louise Eriksson, Per Hall, Mikael Hartman, Ruth ML Warren, Greg Hislop, Anna M Chiarelli, John L Hopper, Kavitha Krishnan, Jingmei Li, et al.

Journal article  |  2014  |  JNCI: Journal of the National Cancer Institute

A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

Habibul Ahsan, Jerry Halpern, Muhammad G Kibriya, Brandon L Pierce, Lin Tong, Eric Gamazon, Valerie McGuire, Anna Felberg, Jianxin Shi, Farzana Jasmine, Shantanu Roy, Rachelle Brutus, Maria Argos, Stephanie Melkonian, Jenny Chang-Claude, Irene Andrulis, John L Hopper, Esther M John, Kathi Malone, Giske Ursin, et al.

Journal article  |  2014  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Associations of Mammographic Dense and Nondense Areas and Body Mass Index With Risk of Breast Cancer

Laura Baglietto, Kavitha Krishnan, Jennifer Stone, Carmel Apicella, Melissa C Southey, Dallas R English, John L Hopper, Graham G Giles

Journal article  |  2014  |  American Journal of Epidemiology

Mammographic breast density refines Tyrer-Cuzick estimates of breast cancer risk in high-risk women: findings from the placebo arm of the International Breast Cancer Intervention Study I

Jane Warwick, Hanna Birke, Jennifer Stone, Ruth ML Warren, Elizabeth Pinney, Adam R Brentnall, Stephen W Duffy, Anthony Howell, Jack Cuzick

Journal article  |  2014  |  Breast Cancer Research

Mammographic density phenotypes and risk of breast cancer: a meta-analysis.

A Pettersson, RE Graff, G Ursin, ID Santos Silva, V McCormack, L Baglietto, C Vachon, MF Bakker, GG Giles, KS Chia, K Czene, L Eriksson, P Hall, M Hartman, RML Warren, G Hislop, AM Chiarelli, JL Hopper, K Krishnan, J Li, et al.

Journal article  |  2014  |  Journal of the National Cancer Institute

Explaining Variance in the Cumulus Mammographic Measures That Predict Breast Cancer Risk: A Twins and Sisters Study

Tuong L Nguyen, Daniel F Schmidt, Enes Makalic, Gillian S Dite, Jennifer Stone, Carmel Apicella, Minh Bui, Robert J MacInnis, Fabrice Odefrey, Jennifer N Cawson, Susan A Treloar, Melissa C Southey, Graham G Giles, John L Hopper

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

Montserrat Garcia-Closas, Fergus J Couch, Sara Lindstrom, Kyriaki Michailidouo, Marjanka K Schmidt, Mark N Brook, Nick Orr, Suhn Kyong Rhie, Elio Riboli, Heather S Feigelson, Loic Le Marchand, Julie E Buring, Diana Eccles, Penelope Miron, Peter A Fasching, Hiltrud Brauch, Jenny Chang-Claude, Jane Carpenter, Andrew K Godwin, Heli Nevanlinna, et al.

Journal article  |  2013  |  Nature Genetics

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Kyriaki Michailidou, Per Hall, Anna Gonzalez-Neira, Maya Ghoussaini, Joe Dennis, Roger L Milne, Marjanka K Schmidt, Jenny Chang-Claude, Stig E Bojesen, Manjeet K Bolla, Qin Wang, Ed Dicks, Andrew Lee, Clare Turnbull, Nazneen Rahman, Olivia Fletcher, Julian Peto, Lorna Gibson, Isabel dos Santos Silva, Heli Nevanlinna, et al.

Journal article  |  2013  |  Nature Genetics

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

Afshan Siddiq, Fergus J Couch, Gary K Chen, Sara Lindstrom, Diana Eccles, Robert C Millikan, Kyriaki Michailidou, Daniel O Stram, Lars Beckmann, Suhn Kyong Rhie, Christine B Ambrosone, Kristiina Aittomaki, Pilar Amiano, Carmel Apicella, Laura Baglietto, Elisa V Bandera, Matthias W Beckmann, Christine D Berg, Leslie Bernstein, Carl Blomqvist, et al.

Journal article  |  2012  |  Human Molecular Genetics

Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.

undefined Irish Schizophrenia Genomics Consortium and the Wellcome Trust Case Control Consortium 2

Journal article  |  2012  |  Biological Psychiatry

BACKGROUND: We performed a genome-wide association study (GWAS) to identify common risk variants for schizophrenia. METHODS: The d..

Identification of a novel percent mammographic density locus at 12q24

Kristen N Stevens, Sara Lindstrom, Christopher G Scott, Deborah Thompson, Thomas A Sellers, Xianshu Wang, Alice Wang, Elizabeth Atkinson, David N Rider, Jeanette E Eckel-Passow, Jajini S Varghese, Tina Audley, Judith Brown, Jean Leyland, Robert N Luben, Ruth ML Warren, Ruth JF Loos, Nicholas J Wareham, Jingmei Li, Per Hall, et al.

Journal article  |  2012  |  Human Molecular Genetics

Inference about Causation from Examination of Familial Confounding: Application to Longitudinal Twin Data on Mammographic Density Measures that Predict Breast Cancer Risk

Jennifer Stone, Gillian S Dite, Graham G Giles, Jennifer Cawson, Dallas R English, John L Hopper

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention

Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures that Predict Breast Cancer Risk

Celine M Vachon, Christopher G Scott, Peter A Fasching, Per Hall, Rulla M Tamimi, Jingmei Li, Jennifer Stone, Carmel Apicella, Fabrice Odefrey, Gretchen L Gierach, Sebastian M Jud, Katharina Heusinger, Matthias W Beckmann, Marina Pollan, Pablo Fernandez-Navarro, Anna Gonzalez-Neira, Javier Benitez, Carla H van Gils, Mariette Lokate, N Charlotte Onland-Moret, et al.

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention

Mammographic Breast Density and Breast Cancer: Evidence of a Shared Genetic Basis

Jajini S Varghese, Deborah J Thompson, Kyriaki Michailidou, Sara Lindstroem, Clare Turnbull, Judith Brown, Jean Leyland, Ruth ML Warren, Robert N Luben, Ruth J Loos, Nicholas J Wareham, Johanna Rommens, Andrew D Paterson, Lisa J Martin, Celine M Vachon, Christopher G Scott, Elizabeth J Atkinson, Fergus J Couch, Carmel Apicella, Melissa C Southey, et al.

Journal article  |  2012  |  Cancer Research

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

P Jia, L Wang, AH Fanous, X Chen, KS Kendler, Z Zhao, DW Morris, CT O'Dushlaine, E Kenny, EM Quinn, M Gill, A Corvin, MC O'Donovan, GK Kirov, NJ Craddock, PA Holmans, NM Williams, L Georgieva, I Nikolov, N Norton, et al.

Journal article  |  2012  |  Journal of Medical Genetics

The association between mammographic density measures and aspirin or other NSAID use

Jennifer Stone, Lisa Willenberg, Carmel Apicella, Susan Treloar, John Hopper

Journal article  |  2012  |  Breast Cancer Research and Treatment

Validation of a short version of the glaucoma medication self-efficacy questionnaire

Betsy Sleath, Susan J Blalock, Jennifer L Stone, Asheley Cockrell Skinner, David Covert, Kelly Muir, Alan L Robin

Journal article  |  2012  |  British Journal of Ophthalmology

Bodyweight and other correlates of symptom-detected breast cancers in a population offered screening

Anne Kricker, Tracey DiSipio, Jennifer Stone, Chris Goumas, Jane E Armes, Dorota M Gertig, Bruce K Armstrong

Journal article  |  2012  |  Cancer Causes & Control

Are genetic and environmental components of variance in mammographic density measures that predict breast cancer risk independent of within-twin pair differences in body mass index?

Gillian S Dite, Jennifer Stone, Anna M Chiarelli, Graham G Giles, Dallas R English, Jennifer C Cawson, John L Hopper

Journal article  |  2012  |  Breast Cancer Research and Treatment

Improved imputation of common and uncommon SNPs with a new reference set.

Zhaoming Wang, Kevin B Jacobs, Meredith Yeager, Amy Hutchinson, Joshua Sampson, Nilanjan Chatterjee, Demetrius Albanes, Sonja I Berndt, Charles C Chung, W Ryan Diver, Susan M Gapstur, Lauren R Teras, Christopher A Haiman, Brian E Henderson, Daniel Stram, Xiang Deng, Ann W Hsing, Jarmo Virtamo, Michael A Eberle, Jennifer L Stone, et al.

Journal article  |  2011  |  Nature Genetics

The Relationship between Glaucoma Medication Adherence, Eye Drop Technique, and Visual Field Defect Severity

Betsy Sleath, Susan Blalock, David Covert, Jennifer L Stone, Asheley Cockrell Skinner, Kelly Muir, Alan L Robin

Journal article  |  2011  |  Ophthalmology

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.

X Chen, G Lee, BS Maher, AH Fanous, J Chen, Z Zhao, A Guo, E van den Oord, PF Sullivan, J Shi, DF Levinson, PV Gejman, A Sanders, J Duan, MJ Owen, NJ Craddock, MC O'Donovan, J Blackman, D Lewis, GK Kirov, et al.

Journal article  |  2011  |  Molecular Psychiatry

We conducted data-mining analyses using the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) and molecular gene..

The relationship between bone mineral density and mammographic density in Korean women: The Healthy Twin study

Joohon Sung, Yun-Mi Song, Jennifer Stone, Kayoung Lee

Journal article  |  2011  |  Breast Cancer Research and Treatment

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

J Chen, G Lee, AH Fanous, Z Zhao, P Jia, A O'neill, D Walsh, KS Kendler, X Chen, MC O’Donovan, GK Kirov, NJ Craddock, PA Holmans, NM Williams, L Georgieva, I Nikolov, N Norton, H Williams, D Toncheva, V Milanova, et al.

Journal article  |  2011  |  Schizophrenia Research

Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models.

Ping Chen, Jennifer Stone, Garrett Sullivan, Jeanne A Drisko, Qi Chen

Journal article  |  2011  |  Free Radical Biology and Medicine

Two popular complementary, alternative, and integrative medicine therapies, high-dose intravenous ascorbic acid (AA) and intraveno..

Reproductive factors associated with mammographic density: a Korean co-twin control study

Joohon Sung, Yun-Mi Song, Jennifer Stone, Kayoung Lee, Donghun Lee

Journal article  |  2011  |  Breast Cancer Research and Treatment

Copy number variations on chromosome 12q14 in patients with normal tension glaucoma

John H Fingert, Alan L Robin, Jennifer L Stone, Ben R Roos, Lea K Davis, Todd E Scheetz, Steve R Bennett, Thomas H Wassink, Young H Kwon, Wallace LM Alward, Robert F Mullins, Val C Sheffield, Edwin M Stone

Journal article  |  2011  |  Human Molecular Genetics

Genetic classification of populations using supervised learning.

Michael Bridges, Elizabeth A Heron, Colm O'Dushlaine, Ricardo Segurado, undefined International Schizophrenia Consortium (ISC), Derek Morris, Aiden Corvin, Michael Gill, Carlos Pinto

Journal article  |  2011  |  PLoS ONE

There are many instances in genetics in which we wish to determine whether two candidate populations are distinguishable on the ba..

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility.

C O'Dushlaine, E Kenny, E Heron, G Donohoe, M Gill, D Morris, undefined International Schizophrenia Consortium, A Corvin

Journal article  |  2011  |  Molecular Psychiatry

Susceptibility to schizophrenia and bipolar disorder may involve a substantial, shared contribution from thousands of common genet..

Common variants in ZNF365 are associated with both mammographic density and breast cancer risk

Sara Lindstroem, Celine M Vachon, Jingmei Li, Jajini Varghese, Deborah Thompson, Ruth Warren, Judith Brown, Jean Leyland, Tina Audley, Nicholas J Wareham, Ruth JF Loos, Andrew D Paterson, Johanna Rommens, Darryl Waggott, Lisa J Martin, Christopher G Scott, V Shane Pankratz, Susan E Hankinson, Aditi Hazra, David J Hunter, et al.

Journal article  |  2011  |  Nature Genetics

High-Density Lipoprotein Cholesterol, Obesity, and Mammographic Density in Korean Women: The Healthy Twin Study

Joohon Sung, Yun-Mi Song, Jennifer Stone, Kayoung Lee, Sun-Young Kim

Journal article  |  2011  |  Journal of Epidemiology

Genetic influences on mammographic density in Korean twin and family: the Healthy Twin study

Joohon Sung, Yun-Mi Song, Jennifer Stone, Kayoung Lee, Ji-in Jeong, Sung-Soo Kim

Journal article  |  2010  |  Breast Cancer Research and Treatment

Predicting breast cancer risk using mammographic density measurements from both mammogram sides and views

Jennifer Stone, Jane Ding, Ruth ML Warren, Stephen W Duffy

Journal article  |  2010  |  Breast Cancer Research and Treatment

A map of human genome variation from population-scale sequencing

David Altshuler, Richard M Durbin, Goncalo R Abecasis, David R Bentley, Aravinda Chakravarti, Andrew G Clark, Francis S Collins, Francisco M De la Vega, Peter Donnelly, Michael Egholm, Paul Flicek, Stacey B Gabriel, Richard A Gibbs, Bartha M Knoppers, Eric S Lander, Hans Lehrach, Elaine R Mardis, Gil A McVean, DebbieA Nickerson, Leena Peltonen, et al.

Journal article  |  2010  |  Nature

High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene.

SP Strom, JL Stone, JR Ten Bosch, B Merriman, RM Cantor, DH Geschwind, SF Nelson

Journal article  |  2010  |  Molecular Psychiatry

Chromosome 17q11-q21 is a region of the genome likely to harbor susceptibility to autism (MIM(209850)) based on earlier evidence o..

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function

S Raychaudhuri, JM Korn, SA McCarroll, D Altshuler, P Sklar, S Purcell, MJ Daly, J Stone, S Bergen, C O'Dushlaine, D Ruderfer, P Sklar, E Scolnick, K Chambert, M O'Donovan, G Kirov, N Craddock, P Holmans, N Williams, L Georgieva, et al.

Journal article  |  2010  |  PLoS Genetics

Association of Body Size Measurements and Mammographic Density in Korean Women: The Healthy Twin Study

Joohon Sung, Yun-Mi Song, Jennifer Stone, Kayoung Lee, Sun-Young Kim

Journal article  |  2010  |  Cancer Epidemiology, Biomarkers & Prevention

Sibship Analysis of Associations Between SNP Haplotypes and a Continuous Trait With Application to Mammographic Density

J Stone, LC Gurrin, VM Hayes, MC Southey, JL Hopper, GB Byrnes

Journal article  |  2010  |  Genetic Epidemiology

Common Genetic Variants Associated with Breast Cancer and Mammographic Density Measures That Predict Disease

Fabrice Odefrey, Jennifer Stone, Lyle C Gurrin, Graham B Byrnes, Carmel Apicella, Gillian S Dite, Jennifer N Cawson, Graham G Giles, Susan A Treloar, Dallas R English, John L Hopper, Melissa C Southey

Journal article  |  2010  |  Cancer Research

Influence of High-Dose Estrogen Exposure during Adolescence on Mammographic Density for Age in Adulthood

Helen L Jordan, John L Hopper, Russell J Thomson, Anne M Kavanagh, Dorota M Gertig, Jennifer Stone, Alison J Venn

Journal article  |  2010  |  Cancer Epidemiology, Biomarkers & Prevention

Using mammographic density to predict breast cancer risk: dense area or percentage dense area

Jennifer Stone, Jane Ding, Ruth ML Warren, Stephen W Duffy, John L Hopper

Journal article  |  2010  |  Breast Cancer Research

Determinants of Percentage and Area Measures of Mammographic Density

Jennifer Stone, Ruth ML Warren, Elizabeth Pinney, Jane Warwick, Jack Cuzick

Journal article  |  2009  |  American Journal of Epidemiology

Familial Correlations in Postmenopausal Serum Concentrations of Sex Steroid Hormones and Other Mitogens: A Twins and Sisters Study

Jennifer Stone, Elizabeth Folkerd, Deborah Doody, Chris Schroen, Susan A Treloar, Graham G Giles, Malcolm C Pike, Dallas R English, Melissa C Southey, John L Hopper, Mitch Dowsett

Journal article  |  2009  |  Journal of Clinical Endocrinology & Metabolism

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.

undefined International Schizophrenia Consortium, Shaun M Purcell, Naomi R Wray, Jennifer L Stone, Peter M Visscher, Michael C O'Donovan, Patrick F Sullivan, Pamela Sklar

Journal article  |  2009  |  Nature

Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by hallucinations, delusions and cogniti..

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

Soumya Raychaudhuri, Robert M Plenge, Elizabeth J Rossin, Aylwin CY Ng, undefined International Schizophrenia Consortium, Shaun M Purcell, Pamela Sklar, Edward M Scolnick, Ramnik J Xavier, David Altshuler, Mark J Daly

Journal article  |  2009  |  PLoS Genetics

Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key di..

An objective evaluation of eyedrop instillation in patients with glaucoma.

Jennifer L Stone, Alan L Robin, Gary D Novack, David W Covert, Gerald D Cagle

Journal article  |  2009  |  Archives of Ophthalmology

OBJECTIVES: To evaluate the performance of patients with ocular hypertension and glaucoma who are experienced in the instillation ..

Genomewide association studies: history, rationale, and prospects for psychiatric disorders.

undefined Psychiatric GWAS Consortium Coordinating Committee, Sven Cichon, Nick Craddock, Mark Daly, Stephen V Faraone, Pablo V Gejman, John Kelsoe, Thomas Lehner, Douglas F Levinson, Audra Moran, Pamela Sklar, Patrick F Sullivan

Journal article  |  2009  |  American Journal of Psychiatry

OBJECTIVE: The authors conducted a review of the history and empirical basis of genomewide association studies (GWAS), the rationa..

Mammographic density: a heritable risk factor for breast cancer.

Norman F Boyd, Lisa J Martin, Johanna M Rommens, Andrew D Paterson, Salomon Minkin, Martin J Yaffe, Jennifer Stone, John L Hopper

Journal article  |  2009  |  Methods in Molecular Biology

The appearance of the breast on mammography varies among women, reflecting variations in tissue composition. Stroma and epithelium..

Predictors of Mammographic Density: Insights Gained from a Novel Regression Analysis of a Twin Study

Gillian S Dite, Lyle C Gurrin, Graham B Byrnes, Jennifer Stone, Anoma Gunasekara, Margaret RE McCredie, Dallas R English, Graham G Giles, Jennifer Cawson, Robert A Hegele, Anna M Chiarelli, Martin J Yaffe, Norman F Boyd, John L Hopper

Journal article  |  2008  |  Cancer Epidemiology, Biomarkers & Prevention

Rare chromosomal deletions and duplications increase risk of schizophrenia.

undefined International Schizophrenia Consortium

Journal article  |  2008  |  Nature

Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability ..

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

Manuel AR Ferreira, Michael C O'Donovan, Yan A Meng, Ian R Jones, Douglas M Ruderfer, Lisa Jones, Jinbo Fan, George Kirov, Roy H Perlis, Elaine K Green, Jordan W Smoller, Detelina Grozeva, Jennifer Stone, Ivan Nikolov, Kimberly Chambert, Marian L Hamshere, Vishwajit L Nimgaonkar, Valentina Moskvina, Michael E Thase, Sian Caesar, et al.

Journal article  |  2008  |  Nature Genetics

To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases and 6,209 controls and identif..

Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene.

Maricela Alarcón, Brett S Abrahams, Jennifer L Stone, Jacqueline A Duvall, Julia V Perederiy, Jamee M Bomar, Jonathan Sebat, Michael Wigler, Christa L Martin, David H Ledbetter, Stanley F Nelson, Rita M Cantor, Daniel H Geschwind

Journal article  |  2008  |  The American Journal of Human Genetics

Autism is a genetically complex neurodevelopmental syndrome in which language deficits are a core feature. We describe results fro..

Mammographic density and candidate gene variants: A twins and sisters study

Jennifer Stone, Lyle C Gurrin, Graham B Byrnes, Christopher J Schroen, Susan A Treloar, Emma JD Padilla, Gillian S Dite, Melissa C Southey, Vanessa M Hayes, John L Hopper

Journal article  |  2007  |  Cancer Epidemiology, Biomarkers & Prevention

High density SNP association study of a major autism linkage region on chromosome 17.

Jennifer L Stone, Barry Merriman, Rita M Cantor, Daniel H Geschwind, Stanley F Nelson

Journal article  |  2007  |  Human Molecular Genetics

A region on chromosome 17 has recently been highlighted as linked to autism (MIM[209850]) in multiple studies and evidence has acc..

Mammographic density and the risk and detection of breast cancer

Norman F Boyd, Helen Guo, Lisa J Martin, Limei Sun, Jennifer Stone, Eve Fishell, Roberta A Jong, Greg Hislop, Anna Chiarelli, Salomon Minkin, Martin J Yaffe

Journal article  |  2007  |  New England Journal of Medicine

The heritability of mammographically dense and nondense breast tissue

J Stone, GS Dite, A Gunasekara, DR English, MRE McCredie, GG Giles, JN Cawson, RA Hegele, AM Chiarelli, MJ Yaffe, NF Boyd, JL Hopper

Journal article  |  2006  |  Cancer Epidemiology, Biomarkers & Prevention

Diet and exercise during growth have site-specific skeletal effects: a co-twin control study

S Iuliano-Burns, J Stone, JL Hopper, E Seeman

Journal article  |  2005  |  Osteoporosis International

A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program.

Malcolm S Reid, Burt Angrist, Sherryl A Baker, Siobhan O'leary, Jennifer Stone, Marion Schwartz, Deborah Leiderman, Ann Montgomery, Ahmed Elkashef, Dorota Majewska, James Robinson, John Rotrosen

Journal article  |  2005  |  Substance Abuse

A placebo controlled, double-blind trial of mecamylamine treatment of cocaine dependence was performed in methadone or LAAM mainta..

Replication of autism linkage: fine-mapping peak at 17q21.

Rita M Cantor, Naoko Kono, Jackie A Duvall, Ana Alvarez-Retuerto, Jennifer L Stone, Maricela Alarcón, Stanley F Nelson, Daniel H Geschwind

Journal article  |  2005  |  The American Journal of Human Genetics

Autism is a heritable but genetically complex disorder characterized by deficits in language and in reciprocal social interactions..

Dietary fat and breast cancer risk revisited: A meta-analysis of the published literature

NF Boyd, J Stone, KN Vogt, J Reedy, S Chang

Journal article  |  2004  |  Breast Diseases

Evidence for sex-specific risk alleles in autism spectrum disorder.

Jennifer L Stone, Barry Merriman, Rita M Cantor, Amanda L Yonan, T Conrad Gilliam, Daniel H Geschwind, Stanley F Nelson

Journal article  |  2004  |  The American Journal of Human Genetics

We investigated the genetic aspects of the large sex bias in the prevalence of autism spectrum disorder by monitoring changes in l..

Risk factors for breast cancer associated with mammographic features in Singaporean Chinese women

D Heng, F Gao, R Jong, E Fishell, M Yaffe, L Martin, T Li, J Stone, LM Sun, J Hopper, NF Boyd

Journal article  |  2004  |  Cancer Epidemiology, Biomarkers & Prevention

High levels of dietary fat intake are associated with an increased risk of breast cancer - Meta-analysis

NF Boyd, J Stone, KN Vogt, BS Connelly, LJ Martin, S Minkin, N Potischman

Journal article  |  2004  |  Evidence-based Obstetrics & Gynecology

An evaluation of left sided colonic polyps as a marker for right sided cancers.

R Ryan, P Neary, J Stone, H Mulcahy, D O'Donoghue, K Sheahan, J Hyland

Journal article  |  2004  |  Irish Medical Journal

The detection of a left-sided polyp on flexible sigmoidoscopy has been suggested as providing a heralding sign for right-sided tum..

Dietary fat and breast cancer risk revisited: a meta-analysis of the published literature

NF Boyd, J Stone, KN Vogt, BS Connelly, LJ Martin, S Minkin

Journal article  |  2003  |  British Journal of Cancer

The detection of change in mammographic density

J Stone, A Gunasekara, LJ Martin, M Yaffe, S Minkin, NF Boyd

Journal article  |  2003  |  Cancer Epidemiology Biomarkers and Prevention

The association of breast mitogens with mammographic densities

NF Boyd, J Stone, LJ Martin, R Jong, E Fishel, M Yaffe, G Hammond, S Minkin

Journal article  |  2002  |  British Journal of Cancer

Genetic linkage of attention-deficit/hyperactivity disorder on chromosome 16p13, in a region implicated in autism.

Susan L Smalley, Vlad Kustanovich, Sonia L Minassian, Jennifer L Stone, Matthew N Ogdie, James J McGough, James T McCracken, I Laurence MacPhie, Clyde Francks, Simon E Fisher, Rita M Cantor, Anthony P Monaco, Stanley F Nelson

Journal article  |  2002  |  The American Journal of Human Genetics

Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed behavioral disorder in childhood and likely represe..

A longitudinal study of the effects of menopause on mammographic features.

Norman Boyd, Lisa Martin, Jennifer Stone, Laurie Little, Salomon Minkin, Martin Yaffe

Journal article  |  2002  |  Cancer Epidemiology Biomarkers and Prevention

Menopause has an important influence on risk of breast cancer. We have examined longitudinally the effect of menopause on mammogra..

A longitudinal study of the effects of menopause on mammographic features

N Boyd, L Martin, J Stone, L Little, S Minkin, M Yaffe

Journal article  |  2002  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Heritability of mammographic density, a risk factor for breast cancer

NF Boyd, GS Dite, J Stone, A Gunasekara, DR English, MRE McCredie, GG Giles, D Tritchler, A Chiarelli, MJ Yaffe, JL Hopper

Journal article  |  2002  |  New England Journal of Medicine

A meta-analysis of published literature on waist-to-hip ratio and risk of breast cancer

BS Connolly, C Barnett, KN Vogt, T Li, J Stone, NF Boyd

Journal article  |  2002  |  Nutrition and Cancer

Lack of effect of a low-fat high-carbohydrate diet on ovarian hormones in premenopausal women: results from a randomized trial.

NF Boyd, C Greenberg, L Martin, J Stone, G Hammond, S Minkin, undefined Canadian Diet and Breast Cancer Prevention Study Group

Journal article  |  2002  |  IARC scientific publications

Mammographic densities as a marker of human breast cancer risk and their use in chemoprevention.

NF Boyd, LJ Martin, J Stone, C Greenberg, S Minkin, MJ Yaffe

Journal article  |  2001  |  Current Oncology Reports

Differences in the parenchymal pattern of the breast on mammography reflect differences in the amounts of stromal, epithelial, and..

Clinical evaluation of glimepiride versus glyburide in NIDDM in a double-blind comparative study. Glimepiride/Glyburide Research Group.

DG Dills, J Schneider

Conference Proceedings  |  1996  |  Hormone and Metabolic Research

We report on the results of a one-year, multicenter, randomized, double-blind, parallel-group titration study of the new sulfonylu..