Dianna Hocking

The multifunctional enzyme S-adenosylhomocysteine/methylthioadenosine nucleosidase is a key metabolic enzyme in the virulence of Salmonella enterica var Typhimurium.

Asma U Husna, Nancy Wang, Jonathan J Wilksch, Hayley J Newton, Dianna M Hocking, Iain D Hay, Simon A Cobbold, Mark R Davies, Malcolm J McConville, Trevor Lithgow, Richard A Strugnell

Journal article  |  2019  |  Biochemical Journal

Key physiological differences between bacterial and mammalian metabolism provide opportunities for the development of novel antimi..

Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome

Kim R Simpfendorfer, Nancy Wang, Dedreia L Tull, David P De Souza, Amsha Nahid, Andre Mu, Dianna M Hocking, John S Pedersen, Odilia LC Wijburg, Malcolm J McConville, Richard A Strugnell

Journal article  |  2019  |  Molecular Medicine

Antibacterial activity of rhodomyrtone on Clostridium difficile vegetative cells and spores in vitro

Sutthirat Srisuwan, Kate E Mackin, Dianna Hocking, Dena Lyras, Vicki Bennett-Wood, Supayang P Voravuthikunchai, Roy M Robins-Browne

Journal article  |  2018  |  International Journal of Antimicrobial Agents

Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium

Asma Ul Husna, Nancy Wang, Simon A Cobbold, Hayley J Newton, Dianna M Hocking, Jonathan J Wilksch, Timothy A Scott, Mark R Davies, Jay C Hinton, Jai J Tree, Trevor Lithgow, Malcolm J McConville, Richard A Strugnell

Journal article  |  2018  |  Journal of Biological Chemistry

Control of Virulence Gene Expression by the Master Regulator, CfaD, in the Prototypical Enterotoxigenic Escherichia coli Strain, H10407

Carla Hodson, Ji Yang, Dianna M Hocking, Kristy Azzopardi, Qianyu Chen, Jessica K Holien, Michael W Parker, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2017  |  Frontiers in Microbiology

Are Escherichia coli Pathotypes Still Relevant in the Era of Whole-Genome Sequencing?

Roy M Robins-Browne, Kathryn E Holt, Danielle J Ingle, Dianna M Hocking, Ji Yang, Marija Tauschek

Journal article  |  2016  |  Frontiers in Cellular and Infection Microbiology

Evolution of atypical enteropathogenic E. coli by repeated acquisition of LEE pathogenicity island variants

Danielle J Ingle, Marija Tauschek, David J Edwards, Dianna M Hocking, Derek J Pickard, Kristy I Azzopardi, Thakshila Amarasena, Vicki Bennett-Wood, Jaclyn S Pearson, Boubou Tamboura, Martin Antonio, John B Ochieng, Joseph Oundo, Inacio Mandomando, Shahida Qureshi, Thandavarayan Ramamurthy, Anowar Hossain, Karen L Kotloff, James P Nataro, Gordon Dougan, et al.

Journal article  |  2016  |  Nature Microbiology

Positive Autoregulation of mrkHI by the Cyclic Di-GMP-Dependent MrkH Protein in the Biofilm Regulatory Circuit of Klebsiella pneumoniae

Jason WH Tan, Jonathan J Wilksch, Dianna M Hocking, Nancy Wang, Yogitha N Srikhanta, Marija Tauschek, Trevor Lithgow, Roy M Robins-Browne, Ji Yang, Richard A Strugnell

Journal article  |  2015  |  Journal of Bacteriology

Evolutionary Adaptation of an AraC-Like Regulatory Protein in Citrobacter rodentium and Escherichia Species

Aimee Tan, Nicola K Petty, Dianna Hocking, Vicki Bennett-Wood, Matthew Wakefield, Judyta Praszkier, Marija Tauschek, Ji Yang, Roy Robins-Browne

Journal article  |  2015  |  Infection and Immunity

In situ formation of antimicrobial silver nanoparticles and the impregnation of hydrophobic polycaprolactone matrix for antimicrobial medical device applications

Phong A Tran, Dianna M Hocking, Andrea J O'Connor

Journal article  |  2015  |  Materials Science and Engineering: C

Control of Acid Resistance Pathways of Enterohemorrhagic Escherichia coli Strain EDL933 by PsrB, a Prophage-Encoded AraC-Like Regulator

Ji Yang, Thomas W Russell, Dianna M Hocking, Jennifer K Bender, Yogitha N Srikhanta, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2015  |  Infection and Immunity

Transcriptional Activation of the mrkA Promoter of the Klebsiella pneumoniae Type 3 Fimbrial Operon by the c-di-GMP-Dependent MrkH Protein

Ji Yang, Jonathan J Wilksch, Jason WH Tan, Dianna M Hocking, Chaille T Webb, Trevor Lithgow, Roy M Robins-Browne, Richard A Strugnell

Journal article  |  2013  |  PLoS One

Control of Bacterial Virulence by the RalR Regulator of the Rabbit-Specific Enteropathogenic Escherichia coli Strain E22

Yogitha N Srikhanta, Dianna M Hocking, Matthew J Wakefield, Ellen Higginson, Roy M Robins-Browne, Ji Yang, Marija Tauschek

Journal article  |  2013  |  Infection and Immunity

Disarming Bacterial Virulence through Chemical Inhibition of the DNA Binding Domain of an AraC-like Transcriptional Activator Protein

Ji Yang, Dianna M Hocking, Catherine Cheng, Con Dogovski, Matthew A Perugini, Jessica K Holien, Michael W Parker, Elizabeth L Hartland, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2013  |  Journal of Biological Chemistry

RegR Virulence Regulon of Rabbit-Specific Enteropathogenic Escherichia coli Strain E22

Yogitha N Srikhanta, Dianna M Hocking, Judyta Praszkier, Matthew J Wakefield, Roy M Robins-Browne, Ji Yang, Marija Tauschek

Journal article  |  2013  |  Infection and Immunity

Disarming bacterial virulence through chemical inhibition of the DNA-binding domain of an AraC-like transcriptional activator protein.

J Yang, DM Hocking, CY Cheng, C Dogovski, MA Perugini, JK Holien, MW Parker, EL Hartland, M Tauschek, RM Robins-Browne

Journal article  |  2013  |  Journal of Biological Chemistry

A totally synthetic lipopeptide-based self-adjuvanting vaccine induces neutralizing antibodies against heat-stable enterotoxin from enterotoxigenic Escherichia coli

Weiguang Zeng, Kristy Azzopardi, Dianna Hocking, Chinn Yi Wong, Gorjana Robevska, Marija Tauschek, Roy M Robins-Browne, David C Jackson

Journal article  |  2012  |  Vaccine

The Type II Secretion System and Its Ubiquitous Lipoprotein Substrate, SslE, Are Required for Biofilm Formation and Virulence of Enteropathogenic Escherichia coli

Deborah L Baldi, Ellen E Higginson, Dianna M Hocking, Judyta Praszkier, Rosalia Cavaliere, Catherine E James, Vicki Bennett-Wood, Kristy I Azzopardi, Lynne Turnbull, Trevor Lithgow, Roy M Robins-Browne, Cynthia B Whitchurch, Marija Tauschek

Journal article  |  2012  |  Infection and Immunity

Transcriptional Analysis of the grlRA Virulence Operon from Citrobacter rodentium

Marija Tauschek, Ji Yang, Dianna Hocking, Kristy Azzopardi, Aimee Tan, Emily Hart, Judyta Praszkier, Roy M Robins-Browne

Journal article  |  2010  |  Journal of Bacteriology

Bicarbonate-Mediated Stimulation of RegA, the Global Virulence Regulator from Citrobacter rodentium

Ji Yang, Con Dogovski, Dianna Hocking, Marija Tauschek, Matt Perugini, Roy M Robins-Browne

Journal article  |  2009  |  Journal of Molecular Biology

Ingested antibody targeting bacterial membrane-associated antigens protects suckling mice against infection with Helicobacter pylori

RJ Gorrell, DM Hocking, RM Robins-Browne

Conference Proceedings  |  2007  |  HELICOBACTER

Influence of format on in vitro penetration of antibody fragments through porcine cornea.

HM Brereton, SD Taylor, A Farrall, D Hocking, MA Thiel, M Tea, DJ Coster, KA Williams

Journal article  |  2005  |  British Journal of Ophthalmology

AIM: Antibody fragments, appropriately formulated, can penetrate through the ocular surface and thus have potential as therapeutic..

Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis

BC Ross, L Czajkowski, D Hocking, M Margetts, E Webb, L Rothel, M Patterson, C Agius, S Camuglia, E Reynolds, T Littlejohn, B Gaeta, A Ng, ES Kuczek, JS Mattick, D Gearing, IG Barr

Journal article  |  2001  |  Vaccine

Isolation of recombinant protective Helicobacter pylori antigens.

D Hocking, E Webb, F Radcliff, L Rothel, S Taylor, G Pinczower, C Kapouleas, H Braley, A Lee, C Doidge

Journal article  |  1999  |  Infection and Immunity

A total of seven clones producing both new and previously described Helicobacter pylori proteins were isolated from a library of H..

Enhanced secretory ability for the human factor VIII light chain produced in baculovirus-infected insect cells.

E Webb, J Tkalcevic, S Edwards, D Hocking, I Nisbet

Journal article  |  1996  |  Cytotechnology

The light and truncated heavy chains of human factor VIII, expressed separately in baculovirus-infected insect cells, exhibited di..

Expression of biologically active human factor VIII using a baculovirus vector

E Webb, J Tkalcevic, S Edwards, D Hocking, L Nisbet

Journal article  |  1993  |  Biochemical and Biophysical Research Communications