Dianna Hocking

Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.

Andre Mu, William P Klare, Sarah L Baines, CN Ignatius Pang, Romain Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, et al.

Journal article  |  2023  |  Nat Commun

Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, w..

LPS O Antigen Plays a Key Role in Klebsiella pneumoniae Capsule Retention

Shweta Singh, Jonathan J Wilksch, Rhys A Dunstan, Anna Mularski, Nancy Wang, Dianna Hocking, Leila Jebeli, Hanwei Cao, Abigail Clements, Adam WJ Jenney, Trevor Lithgow, Richard A Strugnell

Journal article  |  2022  |  MICROBIOLOGY SPECTRUM

Despite the importance of encapsulation in bacterial pathogenesis, the biochemical mechanisms and forces that underpin retention o..

Genomic epidemiology of Salmonella Typhi in Central Division, Fiji, 2012 to 2016

Mark R Davies, Sebastian Duchene, Mary Valcanis, Aaron P Jenkins, Adam Jenney, Varanisese Rosa, Andrew J Hayes, Aneley Getahun Strobel, Liam McIntyre, Jake A Lacey, Elizabeth J Klemm, Vanessa K Wong, Aalisha Sahukhan, Helen Thomson, Andrew Page, Dianna Hocking, Nancy Wang, Litia Tudravu, Eric Rafai, Gordon Dougan, et al.

Journal article  |  2022  |  LANCET REGIONAL HEALTH-WESTERN PACIFIC

BACKGROUND: Typhoid fever is endemic in some Pacific Island Countries including Fiji and Samoa yet genomic surveillance is not rou..

CD4( ) T cell immunity to Salmonella is transient in the circulation

Newton G Peres, Nancy Wang, Paul Whitney, Sven Engel, Meghanashree M Shreenivas, Ian Comerford, Dianna M Hocking, Anna B Erazo, Irmgard Foerster, Andreas Kupz, Thomas Gebhardt, Shaun R McColl, Stephen J McSorley, Sammy Bedoui, Richard A Strugnell

Journal article  |  2021  |  PLOS PATHOGENS

While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD..

Re-evaluation of a Neonatal Mouse Model of Infection With Enterotoxigenic Escherichia coli

Carla J Carroll, Dianna M Hocking, Kristy I Azzopardi, Judyta Praszkier, Vicki Bennett-Wood, Kaylani Almeida, Danielle J Ingle, Sarah L Baines, Marija Tauschek, Roy M Robins-Browne

Journal article  |  2021  |  FRONTIERS IN MICROBIOLOGY

Enterotoxigenic E. coli (ETEC) is a common cause of diarrhea in children in low- and middle-income countries, and in travelers to ..

Bacterial Redox Potential Powers Controlled Radical Polymerization

Mitchell D Nothling, Hanwei Cao, Thomas G McKenzie, Dianna M Hocking, Richard A Strugnell, Greg G Qiao

Journal article  |  2021  |  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microbes employ a remarkably intricate electron transport system to extract energy from the environment. The respiratory cascade o..

The Potential Use of Hypochlorous Acid and a Smart Prefabricated Sanitising Chamber to Reduce Occupation-Related COVID-19 Exposure

Kate Nguyen, Bui Dinh, Mahak Hashemi, Dianna M Hocking, Priyan Mendis, Richard A Strugnell, Shyamali C Dharmage

Journal article  |  2021  |  RISK MANAGEMENT AND HEALTHCARE POLICY

This work is part of a project on the development of a smart prefabricated sanitising chamber (SPSC) to provide extra measures aga..

Sympathetic nerves control bacterial clearance

Yugeesh R Lankadeva, Clive N May, Michael J McKinley, Melanie R Neeland, Shuai Ma, Dianna M Hocking, Roy Robins-Browne, Sammy Bedoui, David GS Farmer, Simon R Bailey, Davide Martelli, Robin M McAllen

Journal article  |  2020  |  SCIENTIFIC REPORTS

A neural reflex mediated by the splanchnic sympathetic nerves regulates systemic inflammation in negative feedback fashion, but it..

Prior Ablation of the Splanchnic Sympathetic Nerves Increases Plasma Inflammatory Cytokine Levels and Suppresses Bacteremia in Response to Systemically Administered E. coli in Sheep

Michael McKinley, Kaylani Almeida, Sammy Bedoui, David Farmer, Dianna Hocking, Yugeesh Lankadeva, Davide Martelli, Clive May, Roy Robins-Browne, Robin McAllen

Conference Proceedings  |  2020  |  FASEB JOURNAL

The multifunctional enzyme S-adenosylhomocysteine/methylthioadenosine nucleosidase is a key metabolic enzyme in the virulence of Salmonella enterica var Typhimurium

Asma U Husna, Nancy Wang, Jonathan J Wilksch, Hayley J Newton, Dianna M Hocking, Iain D Hay, Simon A Cobbold, Mark R Davies, Malcolm J McConville, Trevor Lithgow, Richard A Strugnell

Journal article  |  2019  |  BIOCHEMICAL JOURNAL

Key physiological differences between bacterial and mammalian metabolism provide opportunities for the development of novel antimi..