Frank Shann

Association Between Centralization and Outcome for Children Admitted to Intensive Care in Australia and New Zealand: A Population-Based Cohort Study.

Anthony Slater, John Beca, Elizabeth Croston, Julie McEniery, Johnny Millar, Lynda Norton, Andrew Numa, David Schell, Paul Secombe, Lahn Straney, Paul Young, Michael Yung, Belinda Gabbe, Frank Shann, undefined Australian and New Zealand Intensive Care Society Pediatric Study Group and Centre for Outcomes and Resource Evaluation

Journal article  |  2022  |  Pediatr Crit Care Med

OBJECTIVES: To describe regional differences and change over time in the degree of centralization of pediatric intensive care in A..

Pragmatic Randomized Trial of Corticosteroids and Inhaled Epinephrine for Bronchiolitis in Children in Intensive Care

Ben Gelbart, Brent McSharry, Carmel Delzoppo, Simon Erickson, Katherine Lee, Warwick Butt, Miriam Rea, Xiaofang Wang, John Beca, Alex Kazemi, Frank Shann

Journal article  |  2022  |  JOURNAL OF PEDIATRICS

OBJECTIVE: To determine whether the combination of systemic corticosteroids and nebulized epinephrine, compared with standard care..

Discordance Between Diagnosis Tools for Assessing Eczema in Infants: A Challenge for Intervention Trials

Laure F Pittet, Nicole L Messina, Kaya Gardiner, Bridget Freyne, Veronica Abruzzo, Clare Morrison, Peter Vuillermin, Katrina J Allen, Anne-Louise Ponsonby, Roy Robins-Browne, Frank Shann, Katie L Flanagan, Susan Donath, Dan Casalaz, Rod Phillips, Nigel Curtis

Journal article  |  2022  |  DERMATITIS

BACKGROUND: There is no standardized definition for infant eczema, and various tools have been used across studies, precluding dir..

Off-target effects of bacillus Calmette-Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19

Nicole L Messina, Susie Germano, Rebecca McElroy, Rajeev Rudraraju, Rhian Bonnici, Laure F Pittet, Melanie R Neeland, Suellen Nicholson, Kanta Subbarao, Nigel Curtis

Journal article  |  2022  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

BACKGROUND AND OBJECTIVES: Because of its beneficial off-target effects against non-mycobacterial infectious diseases, bacillus Ca..

BCG vaccination to reduce the impact of COVID-19 in healthcare workers: Protocol for a randomised controlled trial (BRACE trial)

Laure F Pittet, Nicole L Messina, Kaya Gardiner, Francesca Orsini, Veronica Abruzzo, Samantha Bannister, Marc Bonten, John L Campbell, Julio Croda, Margareth Dalcolmo, Sonja Elia, Susie Germano, Casey Goodall, Amanda Gwee, Tenaya Jamieson, Bruno Jardim, Tobias R Kollmann, Marcus Vinicius Guimaraes Lacerda, Katherine J Lee, Donna Legge, et al.

Journal article  |  2021  |  BMJ OPEN

INTRODUCTION: BCG vaccination modulates immune responses to unrelated pathogens. This off-target effect could reduce the impact of..

Hospital-acquired complications in critically ill patients

Graeme J Duke, Frank Shann, Cameron Knott, Felix Oberender, David Pilcher, Owen Roodenburg, John D Santamaria

Journal article  |  2021  |  CRITICAL CARE AND RESUSCITATION

Background: The national hospital-acquired complications (HAC) system has been promoted as a method to identify health care errors..

Prevention of infant eczema by neonatal bacille Calmette-Guerin vaccination: The MIS BAIR randomized controlled trial

Laure F Pittet, Nicole L Messina, Kaya Gardiner, Bridget Freyne, Veronica Abruzzo, Kate L Francis, Clare Morrison, Christel Zufferey, Peter Vuillermin, Katrina J Allen, Anne-Louise Ponsonby, Roy Robins-Browne, Frank Shann, Katie L Flanagan, Rod Phillips, Susan Donath, Dan Casalaz, Nigel Curtis

Journal article  |  2021  |  ALLERGY

BACKGROUND: Bacille Calmette-Guérin (BCG) vaccine could play a role in counteracting the rising prevalence of atopic diseases, thr..

Neonatal Bacille Calmette-Guerin Vaccination and Infections in the First Year of Life: The MIS BAIR Randomized Controlled Trial

Nicole L Messina, Laure F Pittet, Kaya Gardiner, Bridget Freyne, Kate L Francis, Christel Zufferey, Veronica Abruzzo, Clare Morrison, Katrina J Allen, Katie L Flanagan, Anne-Louise Ponsonby, Roy Robins-Browne, Frank Shann, Mike South, Peter Vuillermin, Susan Donath, Dan Casalaz, Nigel Curtis

Journal article  |  2021  |  JOURNAL OF INFECTIOUS DISEASES

BACKGROUND: Bacille Calmette-Guérin (BCG) vaccination has beneficial off-target effects that may include protecting against non-my..

A Live-Vaccine-Last Schedule: Saving an Extra Million Lives a Year?

Frank Shann

Journal article  |  2021  |  CLINICAL INFECTIOUS DISEASES

The non-specific and sex-differential effects of vaccines

Peter Aaby, Christine Stabell Benn, Katie L Flanagan, Sabra L Klein, Tobias R Kollmann, David J Lynn, Frank Shann

Journal article  |  2020  |  NATURE REVIEWS IMMUNOLOGY

The textbook view of vaccination is that it functions to induce immune memory of the specific pathogen components of the vaccine, ..