Bronwyn Kingwell

Noninvasive Plaque Imaging to Accelerate Coronary Artery Disease Drug Development

Gemma A Figtree, Philip D Adamson, Charalambos Antoniades, Roger S Blumenthal, Michael Blaha, Matthew Budoff, David S Celermajer, Mark Y Chan, Clara K Chow, Damini Dey, Girish Dwivedi, Nicola Giannotti, Stuart M Grieve, Christian Hamilton-Craig, Bronwyn A Kingwell, Jason C Kovacic, James K Min, David E Newby, Sanjay Patel, Karlheinz Peter, et al.

Journal article  |  2022  |  CIRCULATION

Coronary artery disease (CAD) remains the leading cause of adult mortality globally. Targeting known modifiable risk factors has h..

Preventing the adverse cardiovascular consequences of allogeneic stem cell transplantation with a multi-faceted exercise intervention: the ALLO-Active trial protocol.

Hayley T Dillon, Nicholas J Saner, Tegan Ilsley, David Kliman, Andrew Spencer, Sharon Avery, David W Dunstan, Robin M Daly, Steve F Fraser, Neville Owen, Brigid M Lynch, Bronwyn A Kingwell, Andre La Gerche, Erin J Howden

Journal article  |  2022  |  BMC Cancer

BACKGROUND: Allogeneic stem cell transplantation (allo-SCT) is a potentially lifesaving treatment for high-risk hematological mali..

Rapid cardiovascular aging following allogeneic hematopoietic cell transplantation for hematological malignancy.

Hayley T Dillon, Stephen Foulkes, Yuki A Horne-Okano, David Kliman, David W Dunstan, Robin M Daly, Steve F Fraser, Sharon Avery, Bronwyn A Kingwell, Andre La Gerche, Erin J Howden

Journal article  |  2022  |  Front Cardiovasc Med

INTRODUCTION: Allogeneic hematopoietic cell transplantation (allo-HCT) offers a potential cure for high-risk hematological maligna..

Apolipoprotein A-I for Cardiac Recovery Post-Myocardial Infarction

Adele L Richart, Anna C Calkin, Bronwyn A Kingwell

Journal article  |  2021  |  JACC-BASIC TO TRANSLATIONAL SCIENCE

Different frequencies of active interruptions to sitting have distinct effects on 22 h glycemic control in type 2 diabetes

Ashleigh R Homer, Frances C Taylor, Paddy C Dempsey, Michael J Wheeler, Parneet Sethi, Megan S Grace, Daniel J Green, Neale D Cohen, Robyn N Larsen, Bronwyn A Kingwell, Neville Owen, David W Dunstan

Journal article  |  2021  |  NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

BACKGROUND & AIMS: Whether the frequency of interruptions to sitting time involving simple resistance activities (SRAs), compared ..

Shark liver oil supplementation enriches endogenous plasmalogens and reduces markers of dyslipidemia and inflammation

Sudip Paul, Adam Alexander T Smith, Kevin Culham, Kevin A Gunawan, Jacqueline M Weir, Michelle A Cinel, Kaushala S Jayawardana, Natalie A Mellett, Man KS Lee, Andrew J Murphy, Graeme I Lancaster, Paul J Nestel, Bronwyn A Kingwell, Peter J Meikle

Journal article  |  2021  |  JOURNAL OF LIPID RESEARCH

Plasmalogens are membrane glycerophospholipids with diverse biological functions. Reduced plasmalogen levels have been observed in..

Co-administration of CSL112 (apolipoprotein A-I [human]) with atorvastatin and alirocumab is not associated with increased hepatotoxic or toxicokinetic effects in rats.

Andrea Beyerle, Brandon Greene, Barbara Dietrich, Bronwyn A Kingwell, Priya Panjwani, Samuel D Wright, Eva Herzog

Journal article  |  2021  |  Toxicol Appl Pharmacol

CSL112 (apolipoprotein A-I, apo AI [human]) is an investigational drug in Phase 3 development for risk reduction of early recurren..

Frequency of Interruptions to Sitting Time: Benefits for Postprandial Metabolism in Type 2 Diabetes

Ashleigh R Homer, Frances C Taylor, Paddy C Dempsey, Michael J Wheeler, Parneet Sethi, Melanie K Townsend, Megan S Grace, Daniel J Green, Neale D Cohen, Robyn N Larsen, Bronwyn A Kingwell, Neville Owen, David W Dunstan

Journal article  |  2021  |  DIABETES CARE

OBJECTIVE: To determine whether interrupting sitting with brief bouts of simple resistance activities (SRAs) at different frequenc..

A call to action for new global approaches to cardiovascular disease drug solutions.

Gemma A Figtree, Keith Broadfoot, Barbara Casadei, Robert Califf, Filippo Crea, Grant R Drummond, Jane E Freedman, Tomasz J Guzik, David Harrison, Derek J Hausenloy, Joseph A Hill, James L Januzzi, Bronwyn A Kingwell, Carolyn SP Lam, Calum A MacRae, Frank Misselwitz, Tetsuji Miura, Rebecca H Ritchie, Maciej Tomaszewski, Joseph C Wu, et al.

Journal article  |  2021  |  Eur Heart J

Whilst we continue to wrestle with the immense challenge of implementing equitable access to established evidence-based treatments..

Acute effects of interrupting prolonged sitting on vascular function in type 2 diabetes

Frances C Taylor, David W Dunstan, Ashleigh R Homer, Paddy C Dempsey, Bronwyn A Kingwell, Rachel E Climie, Neville Owen, Neale D Cohen, Robyn N Larsen, Megan Grace, Nina Eikelis, Michael J Wheeler, Melanie K Townsend, Nirav Maniar, Daniel J Green

Journal article  |  2021  |  American Journal of Physiology: Heart and Circulatory Physiology

In healthy and overweight/obese adults, interrupting prolonged sitting with activity bouts mitigates impairment in vascular functi..