Maria Koulmanda

Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory

Thomas B Thornley, Zemin Fang, Savithri Balasubramanian, Rafael A Larocca, Weihua Gong, Shipra Gupta, Eva Csizmadia, Nicolas Degauque, Beom Seok Kim, Maria Koulmanda, Vijay K Kuchroo, Terry B Strom

Journal article  |  2014  |  JOURNAL OF CLINICAL INVESTIGATION

Macrophages characterized as M2 and M2-like regulate immune responses associated with immune suppression and healing; however, the..

Prevention of Nonimmunologic Loss of Transplanted Islets in Monkeys

M Koulmanda, RS Sampathkumar, M Bhasin, A Qipo, Z Fan, G Singh, B Movahedi, M Duggan, V Chipashvili, TB Strom

Journal article  |  2014  |  AMERICAN JOURNAL OF TRANSPLANTATION

The nonimmunologic loss of islets in the pre-, peri-, and early post-islet transplant periods is profound. To determine the potent..

Role of myeloid-derived suppressor cells in mouse pre-sensitized cardiac transplant model

Weihua Gong, Fangmin Ge, Dahai Liu, Yan Wu, Fangbing Liu, Beom Seok Kim, Tao Huang, Maria Koulmanda, Simon C Robson, Terry B Strom

Journal article  |  2014  |  CLINICAL IMMUNOLOGY

Harness of sensitized transplantation remains a clinical challenge particularly in parallel with prolonged cold ischemia time (PCI..

Seeking tolerance indirectly

Maria Koulnrianda

Journal article  |  2012  |  CLINICAL IMMUNOLOGY

Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival

Maria Koulmanda, Manoj Bhasin, Zhigang Fan, Dusan Hanidziar, Nipun Goel, Prabhakar Putheti, Babak Movahedi, Towia A Libermann, Terry B Strom

Journal article  |  2012  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The promise of islet cell transplantation cannot be fully realized in the absence of improvements in engraftment of resilient isle..

The Role of TNF-alpha in Mice with Type 1-and 2-Diabetes

Maria Koulmanda, Manoj Bhasin, Zuheir Awdeh, Andi Qipo, Zhigang Fan, Dusan Hanidziar, Prabhakar Putheti, Hang Shi, Eva Csizuadia, Towia A Libermann, Terry B Strom

Journal article  |  2012  |  PLOS ONE

BACKGROUND: Previously, we have demonstrated that short-term treatment of new onset diabetic Non-obese diabetic (NOD) mice, mice t..

Prolonged Survival of Allogeneic Islets in Cynomolgus Monkeys After Short-Term Triple Therapy

M Koulmanda, A Qipo, Z Fan, N Smith, H Auchincloss, XX Zheng, TB Strom

Journal article  |  2012  |  AMERICAN JOURNAL OF TRANSPLANTATION

Preclinical studies in nonhuman primates (NHP) are particularly useful to evaluate the safety and efficacy of new therapeutic prot..

Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human primates

Timothy Millington, Maria Koulmanda, Choo Ng, Svjetlan Boskovic, Ognjenka M Nadazdin, Gilles Benichou, Xin Xiao Zheng, Terry B Strom, Joren C Madsen

Journal article  |  2012  |  JOURNAL OF HEART AND LUNG TRANSPLANTATION

BACKGROUND: To tilt the immunologic balance toward tolerance and away from rejection, non-human primate recipients of cardiac allo..

Towards cytoprotection in the peritransplant period

Dusan Hanidziar, Maria Koulmanda

Journal article  |  2011  |  SEMINARS IN IMMUNOLOGY

As a consequence of ischemia-reperfusion injury of whole organ transplants and hypoxia-anoxia of cell transplants, transplantation..

Creating transplant tolerance by taming adverse intragraft innate immunity.

Dusan Hanidziar, Maria Koulmanda, Terry B Strom

Journal article  |  2010  |  F1000 Biol Rep

Certain forms of inflammation of an allograft are highly detrimental to the induction and maintenance of transplant tolerance as t..