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Dr

Petranel Ferrao

Honorary
Surgery - Austin Health
Targeted therapeutics; Drug Resistance; Signalling pathways; Phenotypic plasticity; DNA damage checkpoints
immunotherapy resistance
life sciences & biomedicine
science & technology
oncology
emt
melanoma
resistance
combination therapies
Petranel Ferrao's Profile Picture
Dr

Petranel Ferrao

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Cancer Research
Petranel Ferrao's Profile Picture
Dr

Petranel Ferrao

 

Dr Petranel Ferrao has extensive experience in the translational research area of cancer therapies. She completed her PhD from the University of Adelaide for research on “The individual and co-operative effects of the c-MYB and c-KIT oncogenes in murine haemopietic cells”; conducted at the Division of Haematology, Hanson Centre for Cancer Research, Adelaide.

She focussed her early post-doctoral training on translational projects investigating mechanisms of drug resistance to conventional chemotherapeutics and new targeted therapeutics for the treatment of leukaemia. As a Brawn Research Fellow at the University of Newcastle, her team reported on the response and resistance of various KIT mutants to the targeted therapeutic drug Imatinib (Glivec). Their early findings on this work contributed to advancing the clinical development of KIT inhibitor drugs for the treatment of KIT-driven malignancies such as GIST. She gained additional tertiary teaching and commercial experience with a start-up venture, while on a break from academic research. Dr Ferrao has built upon her early post-doctoral expertise in drug resistance, targeted therapies, receptor tyrosine kinases and signalling, to establish several translational projects on identifying predictors/biomarkers of treatment response for patient stratification and determining ways to overcome treatment resistance in melanoma, ovarian cancer, colorectal cancer, lung cancer, pancreatic cancer and various haematological malignancies. Her longer term research vision is to improve therapy outcomes and patient survival rates by utilising novel predictors/biomarkers to define the most optimal treatment strategies for use in a personalised and precision manner.

Scholarly Works

Displaying the 6 most recent scholarly works by Petranel Ferrao.

Credentials

Positions


Honorary

Surgery - Austin Health

Honorary

Clinical Pathology

Education


Bachelor of Science

Adelaide University

Bachelor of Science (Honours, first class)

Adelaide University

Doctor of Philosophy

Adelaide University