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Dr

Petranel Ferrao

Honorary
Clinical Pathology
Targeted therapeutics
Drug Resistance
Signalling pathways
Phenotypic plasticity
DNA damage checkpoints
immunotherapy resistance
life sciences & biomedicine
science & technology
oncology
Petranel Ferrao's Profile Picture
Dr

Petranel Ferrao

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Cancer Research
Petranel Ferrao's Profile Picture
Dr

Petranel Ferrao

 
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Petranel's  Short Profile
 

Projects

Displaying the 3 most recent projects from 3 for Petranel Ferrao.

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UTILISING A NOVEL PREDICTOR TO STRATIFY PATIENTS WITH THERAPY-RESISTANT PANCREATIC CANCER FOR TREATMENT WITH CHK INHIBITOR DRUGS TO IMPROVE RESPONSES AND OUTCOMES

2017 - 2018
Completed
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Overcoming Receptor Tyrosine Kinase mediated resistance to BRAF Inhibitors in metastatic melanoma, colorectal and lung cancers.

The drug Vemurafenib results in good responses in melanoma patients. However, patients become resistant to treatment. We have identified spe..

2013 - 2017
Completed
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Predictors of Sensitivity to CHK Inhibitors in Melanoma

Computational Behavioral Science: Modeling, Analysis, and Visualization of Social and Communicative Behavior Lead PI/Institution: James M. R..

2012 - 2015
Completed

3

Projects

Project Types

3

Research Grant

Additional Information

Scholarly Works

Displaying the 7 most recent scholarly works from 7 for Petranel Ferrao.

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Editorial: Cancer Plasticity and the Microenvironment: Implications for Immunity and Therapy Response

Andreas Behren, Erik W Thompson, Robin L Anderson, Petranel T Ferrao

Journal article  |  2019  |  FRONTIERS IN ONCOLOGY

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PO-508 A novel predictor for stratifying pancreatic cancer patients to DNA damage checkpoint inhibitors

D Yeo, R Jorissen, M Nikfarjam, P Ferrao

Journal article  |  2018  |  ESMO Open

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Taking out the JNK: A window of opportunity to improve cancer therapy

Petranel T Ferrao

Journal article  |  2016  |  MOLECULAR & CELLULAR ONCOLOGY

c-JUN-N-terminal kinase (JNK) signaling is a stress-induced response that enables survival of normal cells and is also utilized by..

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The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma

Rachel Ramsdale, Robert N Jorissen, Frederic Z Li, Sheren Al-Obaidi, Teresa Ward, Karen E Sheppard, Patricia E Bukczynska, Richard J Young, Samantha E Boyle, Mark Shackleton, Gideon Bollag, Georgina V Long, Eugene Tulchinsky, Helen Rizos, Richard B Pearson, Grant A McArthur, Amardeep S Dhillon, Petranel T Ferrao

Journal article  |  2015  |  SCIENCE SIGNALING

Most patients with BRAF-mutant metastatic melanoma display remarkable but incomplete and short-lived responses to inhibitors of th..

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Editorial: Cellular and phenotypic plasticity in cancer

Petranel T Ferrao, Andreas Behren, Robin L Anderson, Erik W Thompson

Journal article  |  2015  |  FRONTIERS IN ONCOLOGY

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Pnenotype switching in melanoma: implications for progression and therapy

Frederic Zhentao Li, Amardeep Singh Dhillon, Robin L Anderson, Grant McArthur, Petranel T Ferrao

Journal article  |  2015  |  FRONTIERS IN ONCOLOGY

Epithelial-mesenchymal transition (EMT) is a key process associated with the progression of epithelial cancers to metastatic disea..

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Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells

PT Ferrao, EP Bukczynska, RW Johnstone, GA McArthur

Journal article  |  2012  |  ONCOGENE

CHK1 and CHK2 function as effectors of cell cycle checkpoint arrest following DNA damage. Small molecule inhibitors of CHK protein..

7

Scholarly Works

Keyword Analysis

Oncology and Carcinogenesis
Clinical Health
Expanding Knowledge

Credentials

Positions

Honorary

Clinical Pathology

Honorary

Surgery - Austin Health

Education

Bachelor of Science

Adelaide University

Bachelor of Science (Honours, first class)

Adelaide University

Doctor of Philosophy

Adelaide University