Lara Shekerdemian

An Analysis of Hospital Mortality After Cardiac Operations in Children With Down Syndrome.

Gurpreet S Dhillon, Nancy S Ghanayem, Christopher R Broda, Seema R Lalani, Carlos M Mery, Lara S Shekerdemian, Steven J Staffa, Shaine A Morris

Journal article  |  2020  |  Seminars in Thoracic and Cardiovascular Surgery

Children with Down syndrome (DS) have lower mortality compared to nonsyndromic (NS) children after atrioventricular septal defect ..

Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units.

Lara S Shekerdemian, Nabihah R Mahmood, Katie K Wolfe, Becky J Riggs, Catherine E Ross, Christine A McKiernan, Sabrina M Heidemann, Lawrence C Kleinman, Anita I Sen, Mark W Hall, Margaret A Priestley, John K McGuire, Konstantinos Boukas, Matthew P Sharron, Jeffrey P Burns, undefined International COVID-19 PICU Collaborative

Journal article  |  2020  |  JAMA Pediatrics

Importance: The recent and ongoing coronavirus disease 2019 (COVID-19) pandemic has taken an unprecedented toll on adults critical..

Epidemiology and Outcomes of Acute Decompensated Heart Failure in Children.

Javier J Lasa, Michael Gaies, Lauren Bush, Wenying Zhang, Mousumi Banerjee, Jeffrey A Alten, Ryan J Butts, Antonio G Cabrera, Paul A Checchia, Justin Elhoff, Angela Lorts, Joseph W Rossano, Kurt Schumacher, Lara S Shekerdemian, Jack F Price

Journal article  |  2020  |  Circulation: Heart Failure

BACKGROUND: Acute decompensated heart failure (ADHF) is a highly morbid condition among adults. Little is known about outcomes in ..

Extracorporeal Membrane Oxygenation Mortality in High-Risk Populations: An Analysis of the Pediatric Health Information System Database.

Ryan D Coleman, Jordana Goldman, Brady Moffett, Danielle Guffey, Laura Loftis, James Thomas, Lara S Shekerdemian

Journal article  |  2020  |  ASAIO Journal

The number of children receiving extracorporeal membrane oxygenation (ECMO) has increased substantially, and includes a growing po..

The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants.

Andrew B Goldstone, Michael Baiocchi, David Wypij, Christian Stopp, Dean B Andropoulos, Joseph Atallah, Andrew M Atz, John Beca, Mary T Donofrio, Kim Duncan, Nancy S Ghanayem, Caren S Goldberg, Hedwig Hövels-Gürich, Fukiko Ichida, Jeffrey P Jacobs, Robert Justo, Beatrice Latal, Jennifer S Li, William T Mahle, Patrick S McQuillen, et al.

Journal article  |  2020  |  European Journal of Cardio-Thoracic Surgery

OBJECTIVES: Neurodevelopmental disability is the most common complication among congenital heart surgery survivors. The Bayley sca..

Impact of feeding mode on neurodevelopmental outcome in infants and children with congenital heart disease.

Line Marie Holst, Faridis Serrano, Lara Shekerdemian, Hanne Berg Ravn, Danielle Guffey, Nancy S Ghanayem, Sonia Monteiro

Journal article  |  2019  |  Congenital Heart Disease

OBJECTIVE: To investigate the impact of feeding mode on neurodevelopmental outcomes in children with congenital heart defects. DES..

Another Outcome Lost to the Benefits of Levosimendan?

Peta MA Alexander, Ayse Akcan-Arikan, Lara S Shekerdemian

Journal article  |  2019  |  Pediatric Critical Care Medicine

Changes in Anesthetic and Postoperative Sedation-Analgesia Practice Associated With Early Extubation Following Infant Cardiac Surgery: Experience From the Pediatric Heart Network Collaborative Learning Study.

Venu Amula, David F Vener, Charles G Pribble, Lori Riegger, Elizabeth C Wilson, Lara S Shekerdemian, Zhining Ou, Angela P Presson, Madolin K Witte, Susan C Nicolson

Journal article  |  2019  |  Pediatric Critical Care Medicine

OBJECTIVES: The Pediatric Heart Network sponsored the multicenter Collaborative Learning Study that implemented a clinical practic..

Ancillary referral patterns in infants after initial assessment in a cardiac developmental outcomes clinic.

Sonia A Monteiro, Faridis Serrano, Rocky Tsang, Eboni Smith Hollier, Danielle Guffey, Lisa Noll, Robert G Voigt, Nancy Ghanayem, Lara Shekerdemian

Journal article  |  2019  |  Congenital Heart Disease

OBJECTIVE: Neurodevelopmental impairment is common after surgery for congenital heart disease (CHD) in infancy. While neurodevelop..

Left Atrial Decompression on Venoarterial Extracorporeal Membrane Oxygenation: Getting to the Heart of the Matter.

Ryan D Coleman, Corey A Chartan, Athar M Qureshi, Lara S Shekerdemian

Journal article  |  2019  |  Pediatric Critical Care Medicine

Characteristics and Outcomes of Pediatric Patients Supported With Ventricular Assist Device-A Multi-Institutional Analysis.

Kriti Puri, Marc M Anders, Sebastian C Tume, Antonio G Cabrera, Jeffrey S Heinle, Jamie C Causey, Yunfei Wang, Brady S Moffett, Lara S Shekerdemian

Journal article  |  2019  |  Pediatric Critical Care Medicine

OBJECTIVES: The use of ventricular assist devices for pediatric patients with heart failure is increasing, but is associated with ..

Variation in Implementation and Outcomes of Early Extubation Practices After Infant Cardiac Surgery.

Katherine E Bates, William T Mahle, Lauren Bush, Janet Donohue, Michael G Gaies, Susan C Nicolson, Lara Shekerdemian, Madolin Witte, Michael Wolf, Judy A Shea, Donald S Likosky, Sara K Pasquali

Journal article  |  2019  |  The Annals of Thoracic Surgery

BACKGROUND: The Pediatric Heart Network Collaborative Learning Study (PHN CLS) increased early extubation after infant tetralogy o..

Sustainability of Infant Cardiac Surgery Early Extubation Practices After Implementation and Study.

Michael Gaies, Sara K Pasquali, Susan C Nicolson, Lara Shekerdemian, Madolin Witte, Michael Wolf, Wenying Zhang, Janet E Donohue, William T Mahle, undefined Pediatric Heart Network Investigators

Journal article  |  2019  |  The Annals of Thoracic Surgery

BACKGROUND: The Pediatric Heart Network Collaborative Learning Study (PHN CLS) successfully changed practice at four hospitals to ..

Hospital Costs Related to Early Extubation After Infant Cardiac Surgery.

Kimberly E McHugh, William T Mahle, Matthew A Hall, Mark A Scheurer, Michael-Alice Moga, John Triedman, Susan C Nicolson, Venugopal Amula, David S Cooper, Marcus Schamberger, Michael Wolf, Lara Shekerdemian, Kristin M Burns, Kathleen E Ash, Dustin M Hipp, Sara K Pasquali, undefined Pediatric Heart Network Investigators

Journal article  |  2019  |  The Annals of Thoracic Surgery

BACKGROUND: The Pediatric Heart Network Collaborative Learning Study (PHN CLS) increased early extubation rates after infant tetra..

Cortisol Response in Children After Second Cardiopulmonary Bypass.

Harish Bangalore, Paul A Checchia, Elena C Ocampo, Jeffrey S Heinle, Charles G Minard, Lara S Shekerdemian

Journal article  |  2019  |  Pediatric Cardiology

A surge in cortisol levels is seen after surgery with cardiopulmonary bypass (CPB). Based on evidence of attenuation of the cortis..

Elevated arterial blood pressure after superior cavo-pulmonary anastomosis is associated with elevated pulmonary artery pressure and cerebrovascular dysautoregulation.

Antonio G Cabrera, Kathleen K Kibler, R Blaine Easley, Michelle Goldsworthy, Lara S Shekerdemian, Dean B Andropoulos, Jeffrey Heinle, Erin A Gottlieb, Eric Vu, Ken M Brady

Journal article  |  2018  |  Pediatric Research

BACKGROUND: Elevated arterial blood pressure (ABP) is common after superior bidirectional cavopulmonary anastomosis (BCPA). The ef..

The Pediatric Heart Network Scholar Award programme: a unique mentored award embedded within a multicentre network.

L LuAnn Minich, Victoria L Pemberton, Lara S Shekerdemian, Morgan M Millar, Jane W Newburger, Andrew C Glatz, Eric M Graham, Richard J Czosek, Sara K Pasquali, Mike Seed, William L Border

Journal article  |  2018  |  Cardiology in the Young

BACKGROUND: The Pediatric Heart Network designed a career development award to train the next generation of clinician scientists i..

Characteristics and outcomes of children with ductal-dependent congenital heart disease and esophageal atresia/tracheoesophageal fistula: A multi-institutional analysis.

Kriti Puri, Shaine A Morris, Carlos M Mery, Yunfei Wang, Brady S Moffett, Jeffrey S Heinle, J Ruben Rodriguez, Lara S Shekerdemian, Antonio G Cabrera

Journal article  |  2018  |  Surgery

BACKGROUND: Extracardiac birth defects are associated with worse outcomes in congenital heart disease (CHD). The impact of esophag..

Extracorporeal Cardiopulmonary Resuscitation in the Pediatric Cardiac Population: In Search of a Standard of Care.

Javier J Lasa, Parag Jain, Tia T Raymond, Charles G Minard, Alexis Topjian, Vinay Nadkarni, Michael Gaies, Melania Bembea, Paul A Checchia, Lara S Shekerdemian, Ravi Thiagarajan

Journal article  |  2018  |  Pediatric Critical Care Medicine

OBJECTIVES: Although clinical and pharmacologic guidelines exist for the practice of cardiopulmonary resuscitation in children (Pe..

The slow burn: are we neglecting potential long-term cardiovascular sequelae of critical illness in children?

Justin J Elhoff, Lara S Shekerdemian

Journal article  |  2017  |  The Lancet Child & Adolescent Health

The Total Inotrope Exposure Score: an extension of the Vasoactive Inotrope Score as a predictor of adverse outcomes after paediatric cardiac surgery.

Harish Bangalore, Michael Gaies, Elena C Ocampo, Jeffrey S Heinle, Danielle Guffey, Charles G Minard, Paul Checchia, Lara S Shekerdemian

Journal article  |  2017  |  Cardiology in the Young

OBJECTIVE: The aim of the present study was to explore and compare the association between a new vasoactive score - the Total Inot..

A decade of pediatric tracheostomies: Indications, outcomes, and long-term prognosis.

Mona L McPherson, Lara Shekerdemian, Michelle Goldsworthy, Charles G Minard, Cynthia S Nelson, Fernando Stein, Jeanine M Graf

Journal article  |  2017  |  Pediatric Pulmonology

OBJECTIVE: To define the mortality and long-term outcomes of children undergoing tracheostomy. DESIGN: Retrospective chart and Tex..

Protein Feeding in Pediatric Acute Kidney Injury Is Not Associated With a Delay in Renal Recovery.

Ursula G Kyle, Ayse Akcan-Arikan, Jaime C Silva, Michelle Goldsworthy, Lara S Shekerdemian, Jorge A Coss-Bu

Journal article  |  2017  |  Journal of Renal Nutrition

OBJECTIVE: Critically ill children with acute kidney injury (AKI) are at high risk of underfeeding. Newer guidelines for nutrition..

Impact of levosimendan on brain injury patterns in a lamb model of infant cardiopulmonary bypass

Poongundran Namachivayam, Joseph J Smolich, Amy E Shields, Sandra Rees, Lee Coleman, Steven B Horton, Igor E Konstantinov, Daniel J Penny, Lara S Shekerdemian

Journal article  |  2014  |  Pediatric Research

Remote ischemic preconditioning in cyanosed neonates undergoing cardiopulmonary bypass: A randomized controlled trial

Bryn O Jones, Salvatore Pepe, Freya L Sheeran, Susan Donath, Pollyanna Hardy, Lara Shekerdemian, Daniel J Penny, Ian McKenzie, Stephen Horton, Christian P Brizard, Yves d'Udekem, Igor E Konstantinov, Michael MH Cheung

Journal article  |  2013  |  Journal of Thoracic and Cardiovascular Surgery

Usefulness of Routine Head Ultrasound Scans Before Surgery for Congenital Heart Disease

Danielle R Rios, Stephen E Welty, Julia K Gunn, John Beca, Charles G Minard, Michelle Goldsworthy, Lee Coleman, Jill V Hunter, Dean B Andropoulos, Lara S Shekerdemian

Journal article  |  2013  |  Pediatrics

New White Matter Brain Injury After Infant Heart Surgery Is Associated With Diagnostic Group and the Use of Circulatory Arrest

John Beca, Julia K Gunn, Lee Coleman, Ayton Hope, Peter W Reed, Rodney W Hunt, Kirsten Finucane, Christian Brizard, Brieana Dance, Lara S Shekerdemian

Journal article  |  2013  |  Circulation

Vitamin D status in critically ill children

Constance Rippel, Michael South, Warwick W Butt, Lara S Shekerdemian

Journal article  |  2012  |  INTENSIVE CARE MEDICINE

Perioperative amplitude-integrated EEG and neurodevelopment in infants with congenital heart disease

Julia K Gunn, John Beca, Rodney W Hunt, Monika Olischar, Lara S Shekerdemian

Journal article  |  2012  |  INTENSIVE CARE MEDICINE

Amplitude-Integrated Electroencephalography and Brain Injury in Infants Undergoing Norwood-Type Operations

Julia K Gunn, John Beca, Daniel J Penny, Stephen B Horton, Yves A d'Udekem, Christian P Brizard, Kirsten Finucane, Monika Olischar, Rodney W Hunt, Lara S Shekerdemian

Journal article  |  2012  |  Annals of Thoracic Surgery

Respiratory syncytial virus immunoprophylaxis in high-risk infants with heart disease

MA Alexander, undefined Eastaugh, undefined Royle, AJ Daley, L Shekerdemian, J Penny

Journal article  |  2012  |  Journal of Paediatrics and Child Health

The influence of bypass temperature on the systemic inflammatory response and organ injury after pediatric open surgery: A randomized trial

Christian F Stocker, Lara S Shekerdemian, Stephen B Horton, Katherine J Lee, Rob Eyres, Yves D'Udekem, Christian P Brizard

Journal article  |  2011  |  Journal of Thoracic and Cardiovascular Surgery

Duration of resuscitation prior to rescue extracorporeal membrane oxygenation impacts outcome in children with heart disease

V Ben Sivarajan, Derek Best, Christian P Brizard, Lara S Shekerdemian, Yves d'Udekem, Warwick Butt

Journal article  |  2011  |  Intensive Care Medicine

Rotating inotrope therapy in a pediatric population with decompensated heart failure

Lindsay M Ryerson, Peta MA Alexander, Warwick W Butt, Frank A Shann, Daniel J Penny, Lara S Shekerdemian

Journal article  |  2011  |  Pediatric Critical Care Medicine

Pandemic H1N1 in Children Requiring Intensive Care in Australia and New Zealand During Winter 2009

Michael Yung, Anthony Slater, Marino Festa, Gary Williams, Simon Erickson, Ville Pettila, Janet Alexander, Belinda D Howe, Lara S Shekerdemian

Journal article  |  2011  |  Pediatrics

Three decades of pediatric intensive care: Who was admitted, what happened in intensive care, and what happened afterward

Poongundran Namachivayam, Frank Shann, Lara Shekerdemian, Anna Taylor, Irene van Sloten, Carmel Delzoppo, Claire Daffey, Warwick Butt

Journal article  |  2010  |  Pediatric Critical Care Medicine

The prevalence of seizures in comatose children in the pediatric intensive care unit: A prospective video-EEG study

Amre Shahwan, Catherine Bailey, Lara Shekerdemian, A Simon Harvey

Journal article  |  2010  |  Epilepsia

Validity of the LaFarge equation for estimation of oxygen consumption in ventilated children with congenital heart disease younger than 3 years-A revisit

Jennifer Rutledge, Andrew Bush, Lara Shekerdemian, Ingram Schulze-Neick, Daniel Penny, Sally Cai, Jia Li

Journal article  |  2010  |  American Heart Journal

Correlation of thromboelastography with standard tests of anticoagulation in paediatric patients receiving extracorporeal life support

DC Alexander, WW Butt, JD Best, SM Donath, PT Monagle, LS Shekerdemian

Journal article  |  2010  |  Thrombosis Research

A Systematic Review of Motor and Cognitive Outcomes After Early Surgery for Congenital Heart Disease

Suzanne H Snookes, Julia K Gunn, Bev J Eldridge, Susan M Donath, Rod W Hunt, Mary P Galea, Lara Shekerdemian

Journal article  |  2010  |  Pediatrics

The role of calcium channel blockers, steroids, anticoagulation, antiplatelet drugs, and endothelin receptor antagonists

Ian Adatia, Lara Shekerdemian

Journal article  |  2010  |  Pediatric Critical Care Medicine

Urotensin-II Contributes to Pulmonary Vasoconstriction in a Perinatal Model of Persistent Pulmonary Hypertension of the Newborn Secondary to Meconium Aspiration Syndrome

Catherine M Simpson, Joseph J Smolich, Lara S Shekerdemian, Daniel J Penny

Journal article  |  2010  |  Pediatric Research

Pre-Operative Brain Injury in Newborn Infants With Transposition of the Great Arteries Occurs at Rates Similar to Other Complex Congenital Heart Disease and Is Not Related to Balloon Atrial Septostomy

John Beca, Julia Gunn, Lee Coleman, Ayton Hope, Laura-Clare Whelan, Thomas Gentles, Terrie Inder, Rod Hunt, Lara Shekerdemian

Journal article  |  2009  |  Journal of the American College of Cardiology

Mechanisms of a reduced cardiac output and the effects of milrinone and levosimendan in a model of infant cardiopulmonary bypass

Christian F Stocker, Lara S Shekerdemian, Martin A Norgaard, Christan P Brizard, Jonathan P Mynard, Steven B Horton, Daniel J Penny

Journal article  |  2007  |  Critical Care Medicine