Enes Makalic

ADMANI: Annotated Digital Mammograms and Associated Non-Image Datasets

Helen ML Frazer, Jennifer SN Tang, Michael S Elliott, Katrina M Kunicki, Brendan Hill, Ravishankar Karthik, Chun Fung Kwok, Carlos A Peña-Solorzano, Yuanhong Chen, Chong Wang, Osamah Al-Qershi, Samantha K Fox, Shuai Li, Enes Makalic, Tuong L Nguyen, Daniel F Schmidt, Prabhathi Basnayake Ralalage, Jocelyn F Lippey, Peter Brotchie, John L Hopper, et al.

Journal article  |  2023  |  Radiology: Artificial Intelligence

Evaluating Multiple Next-Generation Sequencing-Derived Tumor Features to Accurately Predict DNA Mismatch Repair Status.

Romy Walker, Peter Georgeson, Khalid Mahmood, Jihoon E Joo, Enes Makalic, Mark Clendenning, Julia Como, Susan Preston, Sharelle Joseland, Bernard J Pope, Ryan A Hutchinson, Kais Kasem, Michael D Walsh, Finlay A Macrae, Aung K Win, John L Hopper, Dmitri Mouradov, Peter Gibbs, Oliver M Sieber, Dylan E O'Sullivan, et al.

Journal article  |  2023  |  J Mol Diagn

Identifying tumor DNA mismatch repair deficiency (dMMR) is important for precision medicine. Tumor features, individually and in c..

External Validation of the United Kingdom Transplant Benefit Score in Australia and New Zealand

Eunice G Lee, Marcos V Perini, Enes Makalic, Gabriel C Oniscu, Michael A Fink

Journal article  |  2022  |  PROGRESS IN TRANSPLANTATION

Introduction: In Australia and New Zealand, liver allocation is needs based (based on model for end-stage liver disease score). An..

Australian genome-wide association study confirms higher female risk for adult glioma associated with variants in the region of CCDC26

Karen Alpen, Claire M Vajdic, Robert J MacInnis, Roger L Milne, Eng-Siew Koh, Elizabeth Hovey, Rosemary Harrup, Fiona Bruinsma, Tuong L Nguyen, Shuai Li, David Joseph, Geza Benke, Pierre-Antoine Dugue, Melissa C Southey, Graham G Giles, Mark Rosenthal, Katharine J Drummond, Anna K Nowak, John L Hopper, Miroslaw Kapuscinski, et al.

Journal article  |  2022  |  NEURO-ONCOLOGY

BACKGROUND: Glioma accounts for approximately 80% of malignant adult brain cancer and its most common subtype, glioblastoma, has o..

Polygenic risk scores for cardiovascular diseases and type 2 diabetes

Chi Kuen Wong, Enes Makalic, Gillian S Dite, Lawrence Whiting, Nicholas M Murphy, John L Hopper, Richard Allman

Journal article  |  2022  |  PLOS ONE

Polygenic risk scores (PRSs) are a promising approach to accurately predict an individual's risk of developing disease. The area u..

Inflammation and Epigenetic Aging Are Largely Independent Markers of Biological Aging and Mortality

Lachlan Cribb, Allison M Hodge, Chenglong Yu, Sherly X Li, Dallas R English, Enes Makalic, Melissa C Southey, Roger L Milne, Graham G Giles, Pierre-Antoine Dugue

Journal article  |  2022  |  JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Limited evidence exists on the link between inflammation and epigenetic aging. We aimed to (a) assess the cross-sectional and pros..

Does genetic predisposition modify the effect of lifestyle-related factors on DNA methylation?

Chenglong Yu, Allison M Hodge, Ee Ming Wong, Jihoon E Joo, Enes Makalic, Daniel F Schmidt, Daniel D Buchanan, Gianluca Severi, John L Hopper, Dallas R English, Graham G Giles, Roger L Milne, Melissa C Southey, Pierre-Antoine Dugue

Journal article  |  2022  |  EPIGENETICS

Lifestyle-related phenotypes have been shown to be heritable and associated with DNA methylation. We aimed to investigate whether ..

Extracellular vesicular lipids as biomarkers for the diagnosis of Alzheimer’s disease

Huaqi Su, Yepy H Rustam, Colin L Masters, Enes Makalic, Catriona McLean, Andrew F Hill, Kevin J Barnham, Gavin E Reid, Laura J Vella

Journal article  |  2021  |  Alzheimer's & Dementia

An increasing number of studies have revealed that dysregulated lipid homeostasis is associated with the pathological processes th..

Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality

Chenglong Yu, Allison M Hodge, Ee Ming Wong, Jihoon Eric Joo, Enes Makalic, Daniel Schmidt, Daniel D Buchanan, John L Hopper, Graham G Giles, Melissa C Southey, Pierre-Antoine Dugue

Journal article  |  2021  |  CELLS

Genetic variants in FOXO3 are associated with longevity. Here, we assessed whether blood DNA methylation at FOXO3 was associated w..

Smoking Methylation Marks for Prediction of Urothelial Cancer Risk

Chenglong Yu, Kristina M Jordahl, Julie K Bassett, Jihoon Eric Joo, Ee Ming Wong, Maree T Brinkman, Daniel F Schmidt, Damien M Bolton, Enes Makalic, Theodore M Brasky, Aladdin H Shadyab, Lesley F Tinker, Anthony Longano, John L Hopper, Dallas R English, Roger L Milne, Parveen Bhatti, Melissa C Southey, Graham G Giles, Pierre-Antoine Dugue

Journal article  |  2021  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

BACKGROUND: Self-reported information may not accurately capture smoking exposure. We aimed to evaluate whether smoking-associated..