Peter Gibbs

Prognostic significance of postsurgery circulating tumorDNAin nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies

Jeanne Tie, Joshua D Cohen, Serigne N Lo, Yuxuan Wang, Lu Li, Michael Christie, Margaret Lee, Rachel Wong, Suzanne Kosmider, Iain Skinner, Hui Li Wong, Belinda Lee, Matthew E Burge, Desmond Yip, Christos S Karapetis, Timothy J Price, Niall C Tebbutt, Andrew M Haydon, Janine Ptak, Mary J Schaeffer, et al.

Journal article  |  2020  |  International Journal of Cancer

Studies in multiple solid tumor types have demonstrated the prognostic significance of ctDNA analysis after curative intent surger..

Treatment outcomes for patients with metastatic castrate-resistant prostate cancer following docetaxel for hormone-sensitive disease

Andrew Schmidt, Angelyn Anton, Julia Shapiro, Shirley Wong, Arun Azad, Edmond Kwan, Lavinia Spain, Arun Muthusamy, Javier Torres, Phillip Parente, Francis Parnis, Jeffrey Goh, Anthony M Joshua, David Pook, Peter Gibbs, Ben Tran, Andrew Weickhardt

Journal article  |  2020  |  Asia-Pacific Journal of Clinical Oncology

AIM: Optimal treatment for newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC) has evolved, with many patients de..

Subgroup analysis of the ASPirin in Reducing Events in the Elderly randomized clinical trial suggest aspirin did not improve outcomes in older adults with chronic kidney disease.

Rory Wolfe, James B Wetmore, Robyn L Woods, John J McNeil, Hugh Gallagher, Paul Roderick, Rowan Walker, Mark R Nelson, Christopher M Reid, Raj C Shah, Michael E Ernst, Jessica E Lockery, Andrew M Tonkin, Walter P Abhayaratna, Peter Gibbs, Erica M Wood, Suzanne E Mahady, Jeff D Williamson, Geoffrey A Donnan, Geoffrey C Cloud, et al.

Journal article  |  2020  |  Kidney International

The role of aspirin for primary prevention in older adults with chronic kidney disease (CKD) is unclear. Therefore, post hoc analy..

Defining the susceptibility of colorectal cancers to BH3-mimetic compounds.

Ming-Jie Luo, Michelle Palmieri, Chris D Riffkin, Anuratha Sakthianandeswaren, Tirta Mario Djajawi, Yumiko Hirokawa, Victoria Shuttleworth, David H Segal, Christine A White, Duong Nhu, Guillaume Lessene, Margaret Lee, Peter Gibbs, David CS Huang, Oliver M Sieber, Jia-Nan Gong

Journal article  |  2020  |  Cell Death & Disease

Novel targets are required to improve the outcomes for patients with colorectal cancers. In this regard, the selective inhibitor o..

Cancer history and risk factors in healthy older people enrolling in the ASPREE clinical trial

Suzanne G Orchard, Jessica E Lockery, Peter Gibbs, Galina Polekhina, Rory Wolfe, John Zalcberg, Andrew Haydon, John J McNeil, Mark R Nelson, Christopher M Reid, Brenda Kirpach, Anne M Murray, Robyn L Woods

Journal article  |  2020  |  Contemporary Clinical Trials

BACKGROUND: Cancer is a leading cause of death globally. Given the elevated risk of cancer with age and an ageing population, it i..

Simulating Progression-Free and Overall Survival for First-Line Doublet Chemotherapy With or Without Bevacizumab in Metastatic Colorectal Cancer Patients Based on Real-World Registry Data

Koen Degeling, Hui-Li Wong, Hendrik Koffijberg, Azim Jalali, Jeremy Shapiro, Suzanne Kosmider, Rachel Wong, Belinda Lee, Matthew Burge, Jeanne Tie, Desmond Yip, Louise Nott, Adnan Khattak, Stephanie Lim, Susan Caird, Peter Gibbs, Maarten IJzerman

Journal article  |  2020  |  PharmacoEconomics

BACKGROUND: Simulation models utilizing real-world data have potential to optimize treatment sequencing strategies for specific pa..

Metastasectomy and BRAF mutation; an analysis of survival outcome in metastatic colorectal cancer.

Thiru Prasanna, Rachel Wong, Timothy Price, Jeremy Shapiro, Jeanne Tie, Hui-Li Wong, Louise Nott, David Roder, Margaret Lee, Suzanne Kosmider, Azim Jalali, Matthew Burge, Robert Padbury, Guy Maddern, Scott Carruthers, James Moore, Michael Sorich, Christos S Karapetis, Peter Gibbs, Desmond Yip

Journal article  |  2020  |  Current Problems in Cancer

BACKGROUND: Resection of oligometastases improves survival in metastatic colorectal cancer (mCRC). It is unclear whether the benef..

Real-World Treatment and Outcomes of Metastatic Colorectal Cancer Patients With a Poor or Very Poor Performance Status.

Avraham Travers, Azim Jalali, Stephen Begbie, Christine Semira, Suzanne Kosmider, Sumitra Ananda, Rachel Wong, Margaret Lee, Jeremy Shapiro, Matthew Burge, Desmond Yip, Javier Torres, Brigette Ma, Louise Nott, Andrew Dean, Jeanne Tie, Adnan Khattak, Stephanie Lim, Hui-Li Wong, Peter Gibbs

Journal article  |  2020  |  Clinical Colorectal Cancer

BACKGROUND: The management of metastatic colorectal cancer patients with a poor performance status (PS) continues to be a clinical..

Effect of aspirin on cancer incidence and mortality in older adults.

John J McNeil, Peter Gibbs, Suzanne G Orchard, Jessica E Lockery, Wendy B Bernstein, Yin Cao, Leslie Ford, Andrew Haydon, Brenda Kirpach, Finlay Macrae, Catriona McLean, Jeremy Millar, Anne M Murray, Mark R Nelson, Galina Polekhina, Christopher M Reid, Ellen Richmond, Luz Maria Rodríguez, Raj C Shah, Jeanne Tie, et al.

Journal article  |  2020  |  JNCI: Journal of the National Cancer Institute

BACKGROUND: ASPirin in Reducing Events in the Elderly (ASPREE), a randomized double-blind placebo-controlled trial (RCT) of daily ..

Real-world impact of anti-HER2 therapy-related cardiotoxicity in patients with advanced HER2-positive breast cancer

C Conduit, RH de Boer, S Lok, P Gibbs, L Malik, Z Loh, B Yeo, S Greenberg, B Devitt, J Lombard, M Nottage, I Collins, J Torres, M Nolan, L Nott

Journal article  |  2020  |  Asia-Pacific Journal of Clinical Oncology

BACKGROUND: Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly in the sett..

Impact of prior (neo)adjuvant trastuzumab (NAT) exposure on the efficacy of HER2-targeted therapy for metastatic breast cancer

Yada Kanjanapan, Sheau Wen Lok, Peter Gibbs, Richard De Boer, Belinda Yeo, Sally Greenberg, Frances Barnett, Louise Knott, Gary Richardson, Rachel Wong, Michelle Nottage, Ian M Collins, Javier Torres, Janine Lombard, Julie Johns, Michael Harold, Laeeq Malik

Journal article  |  2020  |  Breast Cancer Research and Treatment

PURPOSE: Trastuzumab, pertuzumab, and docetaxel are the standard first-line therapy for HER2-positive (HER2+) metastatic breast ca..

Defining key design elements of registry-based randomised controlled trials: a scoping review

Bill Karanatsios, Khic-Houy Prang, Ebony Verbunt, Justin M Yeung, Margaret Kelaher, Peter Gibbs

Journal article  |  2020  |  TRIALS

BACKGROUND: Traditional randomised controlled trials remain the gold standard for improving clinical care but they do have their l..

Circulating Tumor DNA as a Prognostic Marker in Stage III Colon Cancer Reply

Zhengyi Zhao, Shangli Cai, Zhijie Wang

Journal article  |  2020  |  JAMA Oncology

Neoadjuvant Chemoradiotherapy and Tumor Recurrence in Patients with Early T-Stage Cancer of the Lower Rectum

Ian P Hayes, Elasma Milanzi, Peter Gibbs, Jeanette C Reece

Journal article  |  2020  |  Annals of Surgical Oncology

BACKGROUND: The role neoadjuvant chemoradiotherapy (nCRT) plays in oncological outcomes in early T-stage rectal cancer is uncertai..

Health Economic Models for Metastatic Colorectal Cancer: A Methodological Review

Koen Degeling, Martin Vu, Hendrik Koffijberg, Hui-Li Wong, Miriam Koopman, Peter Gibbs, Maarten IJzerman

Journal article  |  2020  |  PharmacoEconomics

OBJECTIVE: The aim of this systematic review was to provide a comprehensive and detailed review of structural and methodological a..

Systematic Review of Efficacy and Health Economic Implications of Real-world Treatment Sequencing in Prostate Cancer: Where Do the Newer Agents Enzalutamide and Abiraterone Fit in?

Amanda Pereira-Salgado, Edmond Michael Kwan, Ben Tran, Peter Gibbs, Johann De Bono, Maarten IJzerman

Journal article  |  2020  |  European Urology Focus

CONTEXT: Optimal treatment sequencing of abiraterone and enzalutamide in chemotherapy-naïve metastatic castration-resistant prosta..

Trifluridine/tipiracil: A practical guide to its use in the management of refractory metastatic colorectal cancer in Australia

Timothy Price, Matthew Burge, Lorraine Chantrill, Peter Gibbs, Nick Pavlakis, Jeremy Shapiro, Katrin Sjoquist

Journal article  |  2020  |  Asia-Pacific Journal of Clinical Oncology

The prognostic role of inflammatory markers in patients with metastatic colorectal cancer treated with bevacizumab: A translational study [ASCENT]

Stephen John Clarke, Matthew Burge, Kynan Feeney, Peter Gibbs, Kristian Jones, Gavin Marx, Mark P Molloy, Timothy Price, William HH Reece, Eva Segelov, Niall C Tebbutt

Journal article  |  2020  |  PLoS One

BACKGROUND: In spite of demonstrating prognostic and possibly predictive benefit in retrospective cohorts and meta-analyses of can..

Assessing aneuploidy with repetitive element sequencing

Christopher Douville, Joshua D Cohen, Janine Ptak, Maria Popoli, Joy Schaefer, Natalie Silliman, Lisa Dobbyn, Robert E Schoen, Jeanne Tie, Peter Gibbs, Michael Goggins, Christopher L Wolfgang, Tian-Li Wang, Ie-Ming Shih, Rachel Karchin, Anne Marie Lennon, Ralph H Hruban, Cristian Tomasetti, Chetan Bettegowda, Kenneth W Kinzler, et al.

Journal article  |  2020  |  Proceedings of the National Academy of Sciences

We report a sensitive PCR-based assay called Repetitive Element AneupLoidy Sequencing System (RealSeqS) that can detect aneuploidy..

Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer

David S Williams, Dmitri Mouradov, Clare Browne, Michelle Palmieri, Meg J Elliott, Rebecca Nightingale, Catherine G Fang, Rita Li, John M Mariadason, Ian Faragher, Ian T Jones, Leonid Churilov, Niall C Tebbutt, Peter Gibbs, Oliver M Sieber

Journal article  |  2020  |  Modern Pathology

TP53 mutations drive colorectal cancer development, with missense mutations frequently leading to accumulation of abnormal TP53 pr..

Resection of colorectal cancer liver metastases in older patients

Seema Kumari, Christine Semira, Margaret Lee, Belinda Lee, Rachel Wong, Louise Nott, Jeremy Shapiro, Peter Gibbs

Journal article  |  2020  |  ANZ Journal of Surgery

BACKGROUND: Colorectal cancer remains a common cancer in the western world, with liver resection being the only potentially curati..

Utilisation of systemic therapy options in routine treatment of metastatic colorectal cancer in Australia

Rachel Delahunty, Margaret Lee, Hui-Li Wong, Julie Johns, Joseph Mckendrick, Belinda Lee, Suzanne Kosmider, Prasad Cooray, Sumitra Ananda, Jayesh Desai, Ben Tran, Jeanne Tie, Peter Gibbs, Rachel Wong

Journal article  |  2020  |  Internal Medicine Journal

CART-WHEEL.org: An Ethically Approved Online Database for Patient-Entered Data to Facilitate Rare Cancer Research.

Damien Kee, Clare Parker, Susie Bae, Katherine M Tucker, Michelle Harrison, Ibrahim Tohidi-Esfahani, Marita Black, Rachel Delahunty, Sumitra Ananda, Michael Friedlander, Heather E Cunliffe, Peter Gibbs, Jayesh Desai, Judith Trotman, Clare L Scott

Journal article  |  2020  |  JCO Clinical Cancer Informatics

PURPOSE: Rare cancers are challenging for researchers, as clinicians and scientists have difficulty recruiting sufficient patient ..

Quality of life in the FOXFIRE, SIRFLOX and FOXFIRE-global randomised trials of selective internal radiotherapy for metastatic colorectal cancer

Jane Wolstenholme, Francesco Fusco, Alastair M Gray, Joanna Moschandreas, Pradeep S Virdee, Sharon Love, Guy Van Hazel, Peter Gibbs, Harpreet S Wasan, Ricky A Sharma

Journal article  |  2020  |  International Journal of Cancer

CD8( ) tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

Rosemary Millen, Shona Hendry, Vignesh Narasimhan, Rebecca Abbott, Matthew Croxford, Peter Gibbs, Jeanne Tie, Hui-Li Wong, Ian Jones, Suzanne Kosmider, David Byrne, John Zalcberg, Stephen Fox, Jayesh Desai, Kumar Visvanathan, Robert G Ramsay, Ben Tran

Journal article  |  2020  |  Clinical and Translational Immunology

Circulating Tumour DNA to Guide Treatment of Gastrointestinal Malignancies

YH To, B Lee, HL Wong, P Gibbs, J Tie

Journal article  |  2020  |  Visceral Medicine

Background: Gastrointestinal cancers are among the most common cancers worldwide and account for a high proportion of cancer-relat..

Demonstrating the feasibility of collecting secondary, de-identified data on Australian patients receiving treatment as part of a Medicine Access Programme

Sheau W Lok, Richard De Boer, Cassandra Cordwell, Gavin Marx, Peter Fox, Csilla Hasovits, Joseph Rutovitz, Michael Harold, Ben Tran, Hui-Li Wong, Peter Gibbs

Journal article  |  2020  |  Internal Medicine Journal

BACKGROUND: In Australia, data generated from the carefully selected, treated and monitored patients enrolled in clinical trials l..

Epidermal growth factor receptor ligands: targets for optimizing treatment of metastatic colorectal cancer

Siavash Foroughi, Jeanne Tie, Peter Gibbs, Antony Wilks Burgess

Journal article  |  2019  |  Growth Factors

The discovery of epidermal growth factor (EGF) and its receptor (EGFR) revealed the connection between EGF-like ligands, signaling..

Secondary technical resectability of colorectal cancer liver metastases after chemotherapy with or without selective internal radiotherapy in the randomized SIRFLOX trial.

B Garlipp, P Gibbs, GA Van Hazel, R Jeyarajah, RCG Martin, CJ Bruns, H Lang, DM Manas, GM Ettorre, F Pardo, V Donckier, C Benckert, TM van Gulik, D Goéré, M Schoen, J Pratschke, WO Bechstein, AM de la Cuesta, S Adeyemi, J Ricke, et al.

Journal article  |  2019  |  BJS

BACKGROUND: Secondary resection of initially unresectable colorectal cancer liver metastases (CRLM) can prolong survival. The adde..

Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer

Jeanne Tie, Joshua D Cohen, Yuxuan Wang, Michael Christie, Koen Simons, Margaret Lee, Rachel Wong, Suzanne Kosmider, Sumitra Ananda, Joseph McKendrick, Belinda Lee, Jin Hee Cho, Ian Faragher, Ian T Jones, Janine Ptak, Mary J Schaeffer, Natalie Silliman, Lisa Dobbyn, Lu Li, Cristian Tomasetti, et al.

Journal article  |  2019  |  JAMA Oncology

Importance: Adjuvant chemotherapy in patients with stage III colon cancer prevents recurrence by eradicating minimal residual dise..

Circulating tumour DNA in early stage colorectal cancer: can blood tell all?

Yat Hang To, Margaret Lee, Peter Gibbs, Jeanne Tie

Journal article  |  2019  |  Annals of Translational Medicine

How can digital health be used to improve outcomes in pancreatic ductal adenocarcinoma (PDAC)? Examining the potential of the PURPLE translational pancreatic cancer platform

Belinda Lee, Julia Shapiro, Benjamin Thomson, Sumitra Ananda, Lara Lipton, Sue-Anne McLachlan, Rachel Wong, Prasad Cooray, Matthew Burge, Kate Clarke, Sharon Pattison, Mehrdad Nikfarjam, Niall Tebbutt, Marion Harris, Daniel Croagh, David Goldstein, Adnan Nagrial, Rob Zielinski, Amitesh Roy, Cheng Ean Chee, et al.

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Use and impact of perioperative chemotherapy in patients with resected colorectal cancer metastases

Amy Body, Margaret Lee, Hui-Li Wong, Alun Pope, Azim Jalali, Jeremy Shapiro, Suzanne Kosmider, Jeanne Tie, Frances Barnett, Gary Richardson, Desmond Yip, Stephanie Hui-Su Lim, Joe McKendrick, Peter Gibbs, Rachel Wong

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Impact of access to novel therapies on the initial management of castrate-resistant prostate cancer: an Australian multicentre study

Edmond M Kwan, Marie C Semira, Alice RT Bergin, Christine Muttiah, Sophie Beck, Angelyn Anton, David Campbell, Shirley Wong, Mark Rosenthal, Peter Gibbs, Ben Tran

Journal article  |  2019  |  Internal Medicine Journal

BACKGROUND: The impact of regulatory approvals of new therapies for castration-resistant prostate cancer (CRPC) in Australia is un..

Emerging strategies in the initial management of locally advanced rectal cancer

Lucy Gately, Hui-Li Wong, Jeanne Tie, Rachel Wong, Margaret Lee, Belinda Lee, Azim Jalali, Peter Gibbs

Journal article  |  2019  |  Future Oncology

The initial management of locally advanced rectal cancer continues to evolve and formulating the ideal treatment plan remains chal..

Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer

B Lee, L Lipton, J Cohen, J Tie, AA Javed, L Li, D Goldstein, M Burge, P Cooray, A Nagrial, NC Tebbutt, B Thomson, M Nikfarjam, M Harris, A Haydon, B Lawrence, DWM Tai, K Simons, AM Lennon, CL Wolfgang, et al.

Journal article  |  2019  |  Annals of Oncology

BACKGROUND: In early-stage pancreatic cancer, there are currently no biomarkers to guide selection of therapeutic options. This pr..

Clinical Applications of Circulating Tumour DNA in Pancreatic Adenocarcinoma

Matthew Loft, Belinda Lee, Jeanne Tie, Peter Gibbs

Journal article  |  2019  |  Journal of Personalized Medicine

Pancreatic adenocarcinoma remains one of the most aggressive cancers with an ongoing dismal survival rate despite some recent adva..

Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer

Yuxuan Wang, Lu Li, Joshua D Cohen, Isaac Kinde, Janine Ptak, Maria Popoli, Joy Schaefer, Natalie Silliman, Lisa Dobbyn, Jeanne Tie, Peter Gibbs, Cristian Tomasetti, Kenneth W Kinzler, Nickolas Papadopoulos, Bert Vogelstein, Louise Olsson

Journal article  |  2019  |  JAMA Oncology

Importance: For patients with resected, nonmetastatic colorectal cancer (CRC), the optimal surveillance protocol remains unclear. ..

Phase II APEC trial: The impact of primary tumor side on outcomes of first-line cetuximab plus FOLFOX or FOLFIRI in patients with RAS wild-type metastatic colorectal cancer

Timothy Price, Lin Shen, Brigette Ma, Regina Esser, Wenfeng Chen, Peter Gibbs, Robert Lim, Ann-Lii Cheng

Journal article  |  2019  |  Asia-Pacific Journal of Clinical Oncology

The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations

Rachel Wong, Jeanne Tie, Margaret Lee, Joshua Cohen, Yuxuan Wang, Lu Li, Stephen Ma, Michael Christie, Suzanne Kosmider, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs

Journal article  |  2019  |  International Journal of Cancer

Real-World Use of First-Generation Anti-androgens (FGAs): Their Influence on Patient Outcomes and Subsequent Therapies in Metastatic Castration-Resistant Prostate Cancer (mCPRC)

Richard Kelly, Angelyn Anton, Shirley Wong, Julia Shapiro, Andrew Weickhardt, Arun Azad, Edmond Kwan, Lavinia Spain, Arun Muthusamy, Javier Torres, Phillip Parente, Francis Parnis, Jeffrey Goh, Anthony Joshua, David Pook, Peter Gibbs, Ben Tran

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Evaluation of the transferability of survival calculators for stage II/III colon cancer across healthcare systems

Robert N Jorissen, Matthew Croxford, Ian T Jones, Robyn L Wards, Nicholas J Hawkins, Peter Gibbs, Oliver M Sieber

Journal article  |  2019  |  International Journal of Cancer

Inflammation, Biomarkers and Immuno-Oncology Pathways in Pancreatic Cancer

Belinda Lee, Peter Gibbs

Journal article  |  2019  |  Journal of Personalized Medicine

Right versus left sided metastatic colorectal cancer: Teasing out clinicopathologic drivers of disparity in survival

Shehara Mendis, Sophie Beck, Belinda Lee, Margaret Lee, Rachel Wong, Suzanne Kosmider, Jeremy Shapiro, Desmond Yip, Simone Steel, Louise Nott, Ross Jennens, Lara Lipton, Matthew Burge, Kathryn Field, Sumitra Ananda, Hui-Li Wong, Peter Gibbs

Journal article  |  2019  |  Asia-Pacific Journal of Clinical Oncology

Registry-based randomized clinical trials as a method to improve cancer care in Australia

Siavash Foroughi, Hui-li Wong, Lucy Gately, Margaret Lee, Koen Simons, Jeanne Tie, Antony Wilks Burgess, Peter Gibbs

Journal article  |  2019  |  Asia-Pacific Journal of Clinical Oncology

Answering real world questions using real world data: Understanding dynamic treatment decisions and outcomes in metastatic colorectal cancer (mCRC).

Hui-Li Wong, Koen Degeling, Azim Jalali, Jeremy David Shapiro, Suzanne Kosmider, Rachel Wong, Belinda Lee, Matthew E Burge, Jeanne Tie, Desmond Yip, Louise M Nott, Muhammad Adnan Khattak, Stephanie Hui-Su Lim, Susan Caird, Maarten J Ijzerman, Peter Gibbs

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Metastasectomy and BRAF mutation: An analysis of survival outcome in metastatic colorectal cancer.

Thiru Prasanna, Rachel Wong, Timothy Jay Price, Jeremy David Shapiro, Jeanne Tie, Hui-Li Wong, Louise M Nott, David Roder, Margaret Lee, Suzanne Kosmider, Azim Jalali, Matthew E Burge, Robert Padbury, Guy Maddern, James Moore, Scott Carruthers, Michael Sorich, Christos Stelios Karapetis, Peter Gibbs, Desmond Yip

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

A pooled analysis of multicenter cohort studies of post-surgery circulating tumor DNA (ctDNA) in early stage colorectal cancer (CRC).

Jeanne Tie, Joshua Cohen, Yuxuan Wang, Lu Li, Margaret Lee, Rachel Wong, Suzanne Kosmider, Hui-Li Wong, Belinda Lee, Matthew E Burge, Desmond Yip, Christos Stelios Karapetis, Timothy Jay Price, Niall C Tebbutt, Andrew Mark Haydon, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

UNDERSTANDING VARIATION IN TREATMENT SEQUENCES AND OUTCOMES IN METASTATIC COLORECTAL CANCER: USING REAL WORLD DATA TO ANSWER REAL WORLD QUESTIONS

HL Wong, K Degeling, A Jalali, J Shapiro, S Kosmider, R Wong, B Lee, M Burge, J Tie, D Yip, L Nott, A Khattak, S Lim, S Caird, M IJzerman, P Gibbs

Conference Proceedings  |  2019  |  Value in Health

Baseline Characteristics of Participants in the ASPREE (Aspirin in Reducing Events in the Elderly) Study (vol 72, pg 1586, 2019)

John J McNeil, Robyn L Woods, Mark R Nelson, Anne M Murray, Christopher M Reid, Brenda Kirpach, Elsdon Storey, Raj C Shah, Rory S Wolfe, Andrew M Tonkin, Anne B Newman, Jeff D Williamson, Jessica E Lockery, Karen L Margolis, Michael E Ernst, Walter P Abhayaratna, Nigel Stocks, Sharyn M Fitzgerald, Ruth E Trevaks, Suzanne G Orchard, et al.

Journal article  |  2019  |  The Journals of Gerontology: Series A

Chemotherapy and biologic use in the routine management of metastatic colorectal cancer in Australia: is clinical practice following the evidence?

Christine Semira, Hui-Li Wong, Kathryn Field, Margaret Lee, Belinda Lee, Louise Nott, Jeremy Shapiro, Rachel Wong, Jeanne Tie, Ben Tran, Gary Richardson, Allan Zimet, Lara Lipton, Babak Tamjid, Matthew Burge, Brigette Ma, Julie Johns, Michael Harold, Peter Gibbs

Journal article  |  2019  |  Internal Medicine Journal

Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study

Jeanne Tie, Joshua D Cohen, Yuxuan Wang, Lu Li, Michael Christie, Koen Simons, Hany Elsaleh, Suzanne Kosmider, Rachel Wong, Desmond Yip, Margaret Lee, Tran Ben, David Rangiah, Matthew Burge, David Goldstein, Madhu Singh, Iain Skinner, Ian Faragher, Matthew Croxford, Carolyn Bampton, et al.

Journal article  |  2019  |  Gut

The tumor immune microenvironment differs between metastatic castrate resistant prostate cancer (CRPC) and hormone sensitive prostate cancer (HSPC).

Kobe Chi Yung Yuen, Tran Ben, Peter Gibbs, Angelyn Anton, Sanjeev Mariathasan, Shahneen Kaur Sandhu, Edward Ernest Kadel

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes

David S Williams, Dmitri Mouradov, Robert N Jorissen, Marsali R Newman, Elham Amini, David K Nickless, Julie A Teague, Catherine G Fang, Michelle Palmieri, Marie J Parsons, Anuratha Sakthianandeswaren, Shan Li, Robyn L Ward, Nicholas J Hawkins, Ian Faragher, Ian T Jones, Peter Gibbs, Oliver M Sieber

Journal article  |  2019  |  Gut

Evaluation of Emergent Mutations in Circulating Cell-Free DNA and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Treated with Panitumumab in the ASPECCT Study

Marc Peeters, Timothy Price, Michael Boedigheimer, Tae Won Kim, Paul Ruff, Peter Gibbs, Anne Thomas, Gaston Demonty, Kristina Hool, Agnes Ang

Journal article  |  2019  |  Clinical Cancer Research

Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies

Peter Gibbs, Volker Heinemann, Navesh K Sharma, Julien Taieb, Jens Ricke, Marc Peeters, Michael Findlay, Bridget Robinson, Christopher Jackson, Andrew Strickland, Val Gebski, Mark Van Buskirk, Huaqing Zhao, Guy van Hazel

Journal article  |  2018  |  Clinical Colorectal Cancer

Re-inventing the randomized controlled trial in medical oncology: The registry-based trial

Siavash Foroughi, Hui-li Wong, Lucy Gately, Margaret Lee, Koen Simons, Jeanne Tie, Antony Wilks Burgess, Peter Gibbs

Journal article  |  2018  |  Asia-Pacific Journal of Clinical Oncology

Hypertension as a predictor of advanced colorectal cancer outcome and cetuximab treatment response.

S Sud, C O'Callaghan, C Jonker, C Karapetis, T Price, N Tebbutt, J Shapiro, G Van Hazel, N Pavlakis, P Gibbs, M Jeffrey, L Siu, S Gill, R Wong, D Jonker, D Tu, R Goodwin

Journal article  |  2018  |  Current Oncology

Background: Adrenergic receptor stimulation is involved in the development of hypertension (htn) and has been implicated in cancer..

Impact of Emergent Circulating Tumor DNA RAS Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer

Tae Won Kim, Marc Peeters, Anne Thomas, Peter Gibbs, Kristina Hool, Jianqi Zhang, Agnes Lee Ang, Bruce Allen Bach, Timothy Price

Journal article  |  2018  |  Clinical Cancer Research

The survival outcome of patients with metastatic colorectal cancer based on the site of metastases and the impact of molecular markers and site of primary cancer on metastatic pattern

Thiru Prasanna, Christos S Karapetis, David Roder, Jeanne Tie, Robert Padbury, Timothy Price, Rachel Wong, Jeremy Shapiro, Louise Nott, Margaret Lee, Yu Jo Chua, Paul Craft, Cynthia Piantadosi, Michael Sorich, Peter Gibbs, Desmond Yip

Journal article  |  2018  |  Acta Oncologica

Mismatch repair deficiency assessment by immunohistochemistry: for Lynch syndrome screening and beyond

Hui-li Wong, Michael Christie, Lucy Gately, Jeanne Tie, Belinda Lee, Christine Semira, Sheau Wen Lok, Rachel Wong, Peter Gibbs

Journal article  |  2018  |  Future Oncology

Use of folfirinox chemotherapy in an Australasian population of pancreatic cancer

A Jalali, M Lee, C Semira, S Banks, HL Wong, S Ananda, L Lipton, JD Shapiro, P Cooray, K Clarke, M Burge, R Wong, JA Shapiro, SA McLachlan, M Harris, D Croagh, N Tebbutt, P Gibbs, B Lee

Journal article  |  2018  |  Annals of Oncology

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

JJ McNeil, MR Nelson, RL Woods, JE Lockery, R Wolfe, CM Reid, B Kirpach, RC Shah, DG Ives, E Storey, J Ryan, AM Tonkin, AB Newman, JD Williamson, KL Margolis, ME Ernst, WP Abhayaratna, N Stocks, SM Fitzgerald, SG Orchard, et al.

Journal article  |  2018  |  New England Journal of Medicine

Effect of Aspirin on Disability-free Survival in the Healthy Elderly

JJ McNeil, RL Woods, MR Nelson, CM Reid, B Kirpach, R Wolfe, E Storey, RC Shah, JE Lockery, AM Tonkin, AB Newman, JD Williamson, KL Margolis, ME Ernst, WP Abhayaratna, N Stocks, SM Fitzgerald, SG Orchard, RE Trevaks, LJ Beilin, et al.

Journal article  |  2018  |  New England Journal of Medicine

Emerging biomarkers for immunomodulatory cancer treatment of upper gastrointestinal, pancreatic and hepatic cancers

Belinda Lee, Ryan Hutchinson, Hui-Li Wong, Jeanne Tie, Tracy Putoczki, Ben Tran, Peter Gibbs, Michael Christie

Journal article  |  2018  |  Seminars in Cancer Biology

Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series

Enric Domingo, Carme Camps, Pamela J Kaisaki, Marie J Parsons, Dmitri Mouradov, Melissa M Pentony, Seiko Makino, Michelle Palmieri, Robyn L Ward, Nicholas J Hawkins, Peter Gibbs, Hanne Askautrud, Dahmane Oukrif, Haitao Wang, Joe Wood, Evie Tomlinson, Yasmine Bark, Kulvinder Kaur, Elaine C Johnstone, Claire Palles, et al.

Journal article  |  2018  |  The Lancet Gastroenterology & Hepatology

Previous Bevacizumab and Efficacy of Later Anti-Epidermal Growth Factor Receptor Antibodies in Metastatic Colorectal Cancer: Results From a Large International Registry

Matthew Burge, Christine Semira, Belinda Lee, Margaret Lee, Suzanne Kosmider, Rachel Wong, Jeremy Shapiro, Brigette Ma, Andrew P Dean, Allan S Zimet, Simone A Steel, Sheau Wen Lok, Javier Torres, Melissa Eastgate, Hui-li Wong, Peter Gibbs

Journal article  |  2018  |  Clinical Colorectal Cancer

Accuracy of administrative coding data in colorectal cancer resections and short-term outcomes

Caroline MacCallum, Nigel Da Silva, Peter Gibbs, Benjamin NJ Thomson, Anita Skandarajah, Ian Hayes

Journal article  |  2018  |  ANZ Journal of Surgery

Stage-based Variation in the Effect of Primary Tumor Side on All Stages of Colorectal Cancer Recurrence and Survival

Margaret M Lee, Andrew MacKinlay, Christine Semira, Christine Schieber, Antonio Jose Jimeno Yepes, Belinda Lee, Rachel Wong, Chathurika KH Hettiarachchige, Natalie Gunn, Jeanne Tie, Hui-Li Wong, Iain Skinner, Ian T Jones, James Keck, Suzanne Kosmider, Ben Tran, Kathryn Field, Peter Gibbs

Journal article  |  2018  |  Clinical Colorectal Cancer

Bridging health access disparities among culturally and linguistically diverse cancer patients: an ongoing challenge

Christine Semira, Hui-Li Wong, Peter Gibbs

Journal article  |  2018  |  Internal Medicine Journal

The Value of Clinical Colorectal Cancer Registries in Colorectal Cancer Research A Systematic Review

Caroline MacCallum, Anita Skandarajah, Peter Gibbs, Ian Hayes

Journal article  |  2018  |  JAMA Surgery

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

Anuratha Sakthianandeswaren, Marie J Parsons, Dmitri Mouradov, Ruth N MacKinnon, Bruno Catimel, Sheng Liu, Michelle Palmieri, Christopher Love, Robert N Jorissen, Shan Li, Lachlan Whitehead, Tracy L Putoczki, Adele Preaudet, Cary Tsui, Cameron J Nowell, Robyn L Ward, Nicholas J Hawkins, Jayesh Desai, Peter Gibbs, Matthias Ernst, et al.

Journal article  |  2018  |  Cancer Discovery

Circulating tumor DNA as a prognostic biomarker in early stage pancreatic cancer.

Belinda Lee, Lara Rachel Lipton, Joshua Cohen, Jeanne Tie, Ammar Asrar Javed, Lu Li, David Goldstein, Prasad Cooray, Adnan Nagrial, Matthew E Burge, Niall C Tebbutt, Mehrdad Nikfarjam, Marion Harris, Anne Marie Lennon, Christopher Lee Wolfgang, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs

Conference Proceedings  |  2018  |  Journal of Clinical Oncology

Serial circulating tumor DNA (ctDNA) analysis as a prognostic marker and a real-time indicator of adjuvant chemotherapy (CT) efficacy in stage III colon cancer (CC).

Jeanne Tie, Joshua Cohen, Yuxuan Wang, Margaret Lee, Rachel Wong, Suzanne Kosmider, Sumitra Ananda, Jin Hee Cho, Ian Faragher, Joseph James McKendrick, Carmela Corfield, Belinda Lee, Kathryn Maree Field, Ian Jones, Lu Li, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs

Conference Proceedings  |  2018  |  Journal of Clinical Oncology

Incidence of pulmonary embolism in patients with newly diagnosed colorectal cancer

Eric S Daniel, Anastasia E Dean, Mingjoe Lim, Mobin Master, Peter Gibbs, Ian Faragher

Journal article  |  2018  |  ANZ Journal of Surgery

How accurate are medical oncologists' impressions of management of metastatic colorectal cancer in Australia?

Lewis Au, Natalie Turner, Hui-Li Wong, Kathryn Field, Belinda Lee, David Boadle, Prasad Cooray, Deme Karikios, Suzanne Kosmider, Lara Lipton, Louise Nott, Phillip Parente, Jeanne Tie, Ben Tran, Rachel Wong, Desmond Yip, Jeremy Shapiro, Peter Gibbs

Journal article  |  2018  |  Asia-Pacific Journal of Clinical Oncology

Use of Bone-Modifying Agents in Australian Men with Castration-Resistant Prostate Cancer (CRPC)

Angelyn Anton, Phillip Parente, Arun Azad, Andrew Weickhardt, Shirley Wong, Julia Shapiro, Javier Torres, Francis Parnis, Christine Semira, Peter Gibbs, Ben Tran, Carmel Pezaro

Conference Proceedings  |  2018  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Detection and localization of surgically resectable cancers with a multi-analyte blood test

Joshua D Cohen, Lu Li, Yuxuan Wang, Christopher Thoburn, Bahman Afsari, Ludmila Danilova, Christopher Douville, Ammar A Javed, Fay Wong, Austin Mattox, Ralph H Hruban, Christopher L Wolfgang, Michael G Goggins, Marco Dal Molin, Tian-Li Wang, Richard Roden, Alison P Klein, Janine Ptak, Lisa Dobbyn, Joy Schaefer, et al.

Journal article  |  2018  |  Science

Impact of primary tumor side (TS) on outcomes of once-every-2-weeks (q2w) cetuximab plus first-line (1L) FOLFOX or FOLFIRI in patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) in the phase 2 APEC trial.

Timothy Jay Price, Lin Shen, Brigette Ma, Regina Esser, Wen-Feng Chen, Peter Gibbs, Robert SC Lim, Ann-Lii Cheng

Conference Proceedings  |  2018  |  Journal of Clinical Oncology

The prognostic role of inflammatory markers in patients with metastatic colorectal cancer treated with bevacizumab.

Stephen John Clarke, Matthew E Burge, Kynan Feeney, Kristian Jones, Peter Gibbs, Mark P Molloy, Gavin M Marx, Timothy Jay Price, William Reece, Eva Segelov, Niall C Tebbutt

Conference Proceedings  |  2018  |  Journal of Clinical Oncology

Precision oncology using a clinician-directed, tailored approach to molecular profiling

Michael Lam, Ben Tran, Sophie Beck, Jeanne Tie, Dishan Herath, James Whittle, Edmond M Kwan, Stephen B Fox, Andrew Fellowes, Sumitra Ananda, Lara Lipton, Peter Gibbs, Mark A Rosenthal, Jayesh Desai

Journal article  |  2018  |  Asia-Pacific Journal of Clinical Oncology

Adjuvant therapy for resected colon cancer 2017, including the IDEA analysis

Monica Tang, Timothy Jay Price, Jeremy Shapiro, Peter Gibbs, Daniel G Haller, Dirk Arnold, Marc Peeters, Eva Segelov, Amitesh Roy, Niall Tebbutt, Nick Pavlakis, Chris Karapetis, Matthew Burge

Journal article  |  2018  |  Expert Review of Anticancer Therapy

Australian contemporary management of synchronous metastatic colorectal cancer

Phillip Malouf, Peter Gibbs, Jeremy Shapiro, Jim Sockler, Stephen Bell

Journal article  |  2018  |  ANZ Journal of Surgery

Circulating tumor DNA as a biomarker to guide therapy in post-operative locally advanced rectal cancer: the best option?

Jeanne Tie, Christine Semira, Peter Gibbs

Journal article  |  2018  |  Expert Review of Molecular Diagnostics

Targeted therapy for metastatic colorectal cancer

Timothy J Price, Monica Tang, Peter Gibbs, Daniel G Haller, Marc Peeters, Dirk Arnold, Eva Segelov, Amitesh Roy, Niall Tebbutt, Nick Pavlakis, Chris Karapetis, Matthew Burge, Jeremy Shapiro

Journal article  |  2018  |  Expert Review of Anticancer Therapy

Impact of anastomotic leak on recurrence and survival after colorectal cancer surgery: a BioGrid Australia analysis

Tarik Sammour, Ian P Hayes, Ian T Jones, Malcolm C Steel, Ian Faragher, Peter Gibbs

Journal article  |  2018  |  ANZ Journal of Surgery

Safety of selective internal radiation therapy (SIRT) with yttrium-90 microspheres combined with systemic anticancer agents: expert consensus

Andrew Kennedy, Daniel B Brown, Jonas Feilchenfeldt, John Marshall, Harpreet Wasan, Marwan Fakih, Peter Gibbs, Alexander Knuth, Bruno Sangro, Michael C Soulen, Gianfranco Pittari, Ricky A Sharma

Journal article  |  2017  |  Journal of Gastrointestinal Oncology

Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study

John J McNeil, Robyn L Woods, Mark R Nelson, Anne M Murray, Christopher M Reid, Brenda Kirpach, Elsdon Storey, Raj C Shah, Rory S Wolfe, Andrew M Tonkin, Anne B Newman, Jeff D Williamson, Jessica E Lockery, Karen L Margolis, Michael E Ernst, Walter P Abhayaratna, Nigel Stocks, Sharyn M Fitzgerald, Ruth E Trevaks, Suzanne G Orchard, et al.

Journal article  |  2017  |  The Journals of Gerontology: Series A

Adequate SIRT activity dose is as important as adequate chemotherapy dose Reply

Ricky A Sharma, Peter Gibbs, Navesh K Sharma, Jens Ricke, Julien Taieb, Joanna Moschandreas, Pradeep S Virdee, Peter Dutton, Guy van Hazel, Harpreet S Wasan

Journal article  |  2017  |  The Lancet Oncology

Overall survival in the FOXFIRE-SIRFLOX-FOXFIRE global prospective randomized studies of first-line SIRT in patients with mCRC

H Wasan, G van Hazel, V Heinemann, N Sharma, J Taieb, J Ricke, M Peeters, M Findlay, P Virdee, SB Love, J Moschandreas, P Dutton, V Gebski, A Gray, R Sharma, P Gibbs

Journal article  |  2017  |  Annals of Oncology

Understanding the role of primary tumour localisation in colorectal cancer treatment and outcomes

Sebastian Stintzing, Sabine Tejpar, Peter Gibbs, Lars Thiebach, Heinz-Josef Lenz

Journal article  |  2017  |  European Journal of Cancer

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

Joshua D Cohen, Ammar A Javed, Christopher Thoburn, Fay Wong, Jeanne Tie, Peter Gibbs, C Max Schmidt, Michele T Yip-Schneider, Peter J Allen, Mark Schattner, Randall E Brand, Aatur D Singhi, Gloria M Petersen, Seung-Mo Hong, Song Cheol Kim, Massimo Falconi, Claudio Doglioni, Matthew J Weiss, Nita Ahuja, Jin He, et al.

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials

Harpreet S Wasan, Peter Gibbs, Navesh K Sharma, Julien Taieb, Volker Heinemann, Jens Ricke, Marc Peeters, Michael Findlay, Andrew Weaver, Jamie Mills, Charles Wilson, Richard Adams, Anne Francis, Joanna Moschandreas, Pradeep S Virdee, Peter Dutton, Sharon Love, Val Gebski, Alastair Gray, Guy van Hazel, et al.

Journal article  |  2017  |  The Lancet Oncology

The impact of bevacizumab in metastatic colorectal cancer with an intact primary tumor: Results from a large prospective cohort study

Belinda Lee, Hui-Li Wong, Mark Tacey, Jeanne Tie, Rachel Wong, Margaret Lee, Louise Nott, Jeremy Shapiro, Ross Jennens, Natalie Turner, Ben Tran, Sumitra Ananda, Desmond Yip, Gary Richardson, Phillip Parente, Lionel Lim, Greg Stefanou, Matthew Burge, Mahesh Iddawela, Jeremy Power, et al.

Journal article  |  2017  |  Asia-Pacific Journal of Clinical Oncology

Intratumorous heterogeneity for RAS mutations in a treatment-naive colorectal tumour

Sebastian Lunke, Belinda Lee, Sevastjan Kranz, Peter Gibbs, Paul Waring, Michael Christie

Journal article  |  2017  |  Journal of Clinical Pathology

Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies

U-P Rohr, P Herrmann, K Ilm, H Zhang, S Lohmann, A Reiser, A Muranyi, J Smith, S Burock, M Osterland, K Leith, S Singh, P Brunhoeber, R Bowermaster, J Tie, M Christie, H-L Wong, P Waring, K Shanmugam, P Gibbs, et al.

Journal article  |  2017  |  Annals of Oncology

Background: We assessed the novel MACC1 gene to further stratify stage II colon cancer patients with proficient mismatch repair (p..

Overall survival analysis of the FOXFIRE-SIRFLOX-FOXFIRE global prospective randomized studies of first-line selective internal radiotherapy (SIRT) in patients with liver metastases from colorectal cancer.

Harpreet Wasan, Guy van Hazel, Volker Heinemann, Navesh Sharma, Julien Taieb, Jens Ricke, Marc Peeters, Michael Findlay, Pradeep S Virdee, Sharon Love, Joanna Moschandreas, Peter Dutton, Val Gebski, Alastair Gray, Dave Price, Geoff Bower, Amir Montazeri, Daniel Swinson, Ewan Brown, Greg Wilson, et al.

Journal article  |  2017  |  Annals of Oncology

Survival Impact of Adjuvant Chemotherapy for Resected Locally Advanced Rectal Adenocarcinoma

Rebecca Y Tay, Murtaza Jamnagerwalla, Malcolm Steel, Hui-Li Wong, Joseph J McKendrick, Ian Faragher, Suzanne Kosmider, Ian Hastie, Jayesh Desai, Mark Tacey, Peter Gibbs, Rachel Wong

Journal article  |  2017  |  CLINICAL COLORECTAL CANCER

A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pegfilgrastim in Patients Receiving First-Line FOLFOX/Bevacizumab or FOLFIRI/Bevacizumab for Locally Advanced or Metastatic Colorectal Cancer: Final Results of the Pegfilgrastim and Anti-VEGF Evaluation Study (PAVES)

Tamas Pinter, Zandra Klippel, Alvydas Cesas, Adina Croitoru, Jochen Decaestecker, Peter Gibbs, Yevhen Hotko, Jacek Jassem, Galina Kurteva, Jan Novotny, Seamus O'Reilly, Tomas Salek, Maureen Reiner, Phuong Khanh Morrow, Mi Rim Choi, Sadie Whittaker, Charles Blanke

Journal article  |  2017  |  Clinical Colorectal Cancer

Efficacy, Tolerability, and Biomarker Analyses of Once-Every-2-Weeks Cetuximab Plus First-Line FOLFOX or FOLFIRI in Patients With KRAS or All RAS Wild-Type Metastatic Colorectal Cancer: The Phase 2 APEC Study

Ann-Lii Cheng, Gerardo Cornelio, Lin Shen, Timothy Price, Tsai-Sheng Yang, Ik Joo Chung, Guang-Hai Dai, Jen-Kou Lin, Atul Sharma, Kun-Huei Yeh, Brigette Ma, Adel Zaatar, Zhongzhen Guan, Nehal Masood, Vichien Srimuninnimit, Thomas Yau, Peter Gibbs, Xiuwen Wang, Dinesh Chandra Doval, Seung-Taek Oh, et al.

Journal article  |  2017  |  Clinical Colorectal Cancer

Impact of primary tumour location on survival in patients with metastatic colorectal cancer receiving selective internal radiation therapy and chemotherapy as first-line therapy.

Guy van Hazel, Volker Heinemann, Navesh Sharma, Julien Taieb, Jens Ricke, Marc Peeters, Michael Findlay, Peter Gibbs, undefined SIRFLOX and FOXFIRE-Global trial investigators

Journal article  |  2017  |  Annals of Oncology

Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy /- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer.

Pradeep S Virdee, Joanna Moschandreas, Val Gebski, Sharon B Love, E Anne Francis, Harpreet S Wasan, Guy van Hazel, Peter Gibbs, Ricky A Sharma

Journal article  |  2017  |  JMIR Research Protocols

BACKGROUND: In colorectal cancer (CRC), unresectable liver metastases are associated with a poor prognosis. The FOXFIRE (an open-l..

Treatment sequencing and outcomes in synchronous metastatic rectal cancer.

Madeleine Cornelia Strach, Margaret Lee, Anna Lomax, Michael Ng, Mario Guerrieri, Thiru Prasanna, Hui-li Wong, Belinda Lee, Joseph James McKendrick, Lionel Lim, Suzanne Kosmider, Jeanne Tie, Desmond Yip, Louise M Nott, Julie Johns, Michael Harold, Peter Gibbs, Rachel Wong

Conference Proceedings  |  2017  |  Journal of Clinical Oncology

Examining the impact of regular aspirin use and PIK3CA mutations on survival in stage 2 colon cancer

Caitlin Murphy, Natalie Turner, Hui-Li Wong, Mathu Sinnathamby, Jeanne Tie, Belinda Lee, Jayesh Desai, Iain Skinner, Michael Christie, Ryan Hutchinson, Sebastian Lunke, Paul Waring, Peter Gibbs, Tran Ben

Journal article  |  2017  |  Internal Medicine Journal

Mapping EORTC-QLQ-C30 to EQ-5D-3L in patients with colorectal cancer

Emily-Ruth Marriott, Guy van Hazel, Peter Gibbs, Anthony J Hatswell

Journal article  |  2017  |  Journal of Medical Economics

BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression

David Barras, Edoardo Missiaglia, Pratyaksha Wirapati, Oliver M Sieber, Robert N Jorissen, Chris Love, Peter L Molloy, Ian T Jones, Stephen McLaughlin, Peter Gibbs, Justin Guinney, Iris M Simon, Arnaud D Roth, Fred T Bosman, Sabine Tejpar, Mauro Delorenzi

Journal article  |  2017  |  Clinical Cancer Research

Selective Internal Radiation Therapy/Yttrium-90: Have We Found Its Place? Reply

Guy A van Hazel, Peter Gibbs

Journal article  |  2016  |  Journal of Clinical Oncology

Benefit from cytoreductive nephrectomy and the prognostic role of neutrophil-to-lymphocyte ratio in patients with metastatic renal cell carcinoma

D Day, Y Kanjanapan, E Kwan, D Yip, N Lawrentschuk, ID Davis, AA Azad, S Wong, M Rosenthal, P Gibbs, B Tran

Journal article  |  2016  |  Internal Medicine Journal

Impact of Surgical Complications Following Resection of Locally Advanced Rectal Adenocarcinoma on Adjuvant Chemotherapy Delivery and Survival Outcomes

Murtaza Jamnagerwalla, Rebecca Tay, Malcolm Steel, Jamie Keck, Ian Jones, Ian Faragher, Peter Gibbs, Rachel Wong

Journal article  |  2016  |  Diseases of the Colon & Rectum

Primary Tumor Resection and Overall Survival in Patients With Metastatic Colorectal Cancer Treated With Palliative Intent

Shu Fen Wong, Hui Li Wong, Kathryn M Field, Suzanne Kosmider, Jeanne Tie, Rachel Wong, Mark Tacey, Jeremy Shapiro, Louise Nott, Gary Richardson, Prasad Cooray, Ian Jones, Matthew Croxford, Peter Gibbs

Journal article  |  2016  |  Clinical Colorectal Cancer

Insights into the SIRFLOX study

Peter Gibbs

Journal article  |  2016  |  Hepatic Oncology

Girdin (GIV) Expression as a Prognostic Marker of Recurrence in Mismatch Repair-Proficient Stage II Colon Cancer

Pradipta Ghosh, Jeanne Tie, Andrea Muranyi, Shalini Singh, Patrick Brunhoeber, Katherine Leith, Rebecca Bowermaster, Zhiming Liao, Yifei Zhu, Bonnie LaFleur, Ben Tran, Jayesh Desai, Ian Jones, Matthew Croxford, Rodrigo Jover, Ajay Goel, Paul Waring, Song Hu, Volker Teichgraber, Ulrich-Peter Rohr, et al.

Journal article  |  2016  |  Clinical Cancer Research

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Jeanne Tie, Yuxuan Wang, Cristian Tomasetti, Lu Li, Simeon Springer, Isaac Kinde, Natalie Silliman, Mark Tacey, Hui-Li Wong, Michael Christie, Suzanne Kosmider, Iain Skinner, Rachel Wong, Malcolm Steel, Ben Tran, Jayesh Desai, Ian Jones, Andrew Haydon, Theresa Hayes, Tim J Price, et al.

Journal article  |  2016  |  Science Translational Medicine

Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

Nirosha Suraweera, Dmitri Mouradov, Shan Li, Robert N Jorissen, Debbie Hampson, Anil Ghosh, Neel Sengupta, Mohamed Thaha, Shafi Ahmed, Michael Kirwan, Floor Aleva, David Propper, Roger M Feakins, Tom Vulliamy, Ngaire J Elwood, Pei Tian, Robyn L Ward, Nicholas J Hawkins, Zheng-Zhou Xu, Peter L Molloy, et al.

Journal article  |  2016  |  Oncotarget

Sequencing Circulating Cell-Free DNA: The Potential to Refine Precision Cancer Medicine

Jeanne Tie, Peter Gibbs

Journal article  |  2016  |  Clinical Chemistry

Impact of Primary Tumor Site on Bevacizumab Efficacy in Metastatic Colorectal Cancer

Hui-li Wong, Belinda Lee, Kathryn Field, Anna Lomax, Mark Tacey, Jeremy Shapiro, Joe McKendrick, Allan Zimet, Desmond Yip, Louise Nott, Ross Jennens, Gary Richardson, Jeanne Tie, Suzanne Kosmider, Phillip Parente, Lionel Lim, Prasad Cooray, Tran Ben, Jayesh Desai, Rachel Wong, et al.

Journal article  |  2016  |  CLINICAL COLORECTAL CANCER

SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer

Guy A van Hazel, Volker Heinemann, Navesh K Sharma, Michael PN Findlay, Jens Ricke, Marc Peeters, David Perez, Bridget A Robinson, Andrew H Strickland, Tom Ferguson, Javier Rodriguez, Hendrik Kroening, Ido Wolf, Vinod Ganju, Euan Walpole, Eveline Boucher, Thomas Tichler, Einat Shacham-Shmueli, Alex Powell, Paul Eliadis, et al.

Journal article  |  2016  |  Journal of Clinical Oncology

Update on optimal treatment for metastatic colorectal cancer from the ACTG/AGITG expert meeting: ECCO 2015

Timothy J Price, Subotheni Thavaneswaran, Matthew Burge, Eva Segelov, Daniel G Haller, Cornelis JA Punt, Dirk Arnold, Christos S Karapetis, Niall C Tebbutt, Nick Pavlakis, Peter Gibbs, Jeremy D Shapiro

Journal article  |  2016  |  Expert Review of Anticancer Therapy

The rapidly escalating cost of treating colorectal cancer in Australia

Sumitra Ananda, Suzanne Kosmider, Ben Tran, Kathryn Field, Ian Jones, Iain Skinner, Mario Guerrieri, Michael Chapman, Peter Gibbs

Journal article  |  2016  |  Asia-Pacific Journal of Clinical Oncology

Use and impact of bevacizumab in patients undergoing liver resection for metastatic colorectal cancer in routine clinical practice.

Edmond Michael Kwan, Belinda Lee, Hui-Li Wong, Margaret Lee, Rachel Wong, Jeremy David Shapiro, Matthew E Burge, Lara Rachel Lipton, Suzanne Kosmider, Peter Gibbs

Conference Proceedings  |  2016  |  Journal of Clinical Oncology

Hypertension as a predictor of outcome and treatment response to cetuximab: A retrospective analysis of NCIC CTG CO.17.

Shelly Sud, Christopher J O'Callaghan, Caleb Jonker, Christos Stelios Karapetis, Timothy Jay Price, Niall C Tebbutt, Jeremy David Shapiro, Guy A Van Hazel, Nick Pavlakis, Peter Gibbs, Mark Jeffery, Lillian L Siu, Sharlene Gill, Ralph Wong, Derek J Jonker, Dongsheng Tu, Rachel Anne Goodwin

Conference Proceedings  |  2016  |  Journal of Clinical Oncology

Use and impact of selective internal radiation therapy (SIRT) in routine care patients with metastatic colorectal cancer (mCRC).

Belinda Lee, Hui-Li Wong, Kathryn Maree Field, Louise M Nott, Jeremy David Shapiro, Rachel Wong, Jeremy David Power, Suzanne Kosmider, Lionel Lim, Peter Gibbs

Conference Proceedings  |  2016  |  Journal of Clinical Oncology

Survival impact of the Australian National Bowel Cancer Screening Programme

S Ananda, H Wong, I Faragher, IT Jones, M Steele, S Kosmider, J Desai, J Tie, K Field, R Wong, B Tran, S Bae, P Gibbs

Journal article  |  2016  |  Internal Medicine Journal

SIRFLOX: Differences in site of first progression between mFOLFOX6 /- bevacizumab (bev) versus mFOLFOX6 /- bev plus selective internal radiation therapy (SIRT) in first-line patients (pts) with metastatic colorectal cancer (mCRC).

Peter Gibbs, Volker Heinemann, Navesh K Sharma, Michael PN Findlay, Jens Ricke, Marc Peeters, David Perez, Bridget Anne Robinson, Andrew Strickland, Tom Ferguson, Javier Rodriguez, Hendrik Kroening, Ido Wolf, Vinod Ganju, Euan Thomas Walpole, Eveline Boucher, Thomas E Tichler, Val Gebski, Mark Van Buskirk, Guy A Van Hazel

Conference Proceedings  |  2016  |  Journal of Clinical Oncology

Analysis of local chronic inflammatory cell infiltrate combined with systemic inflammation improves prognostication in stage II colon cancer independent of standard clinicopathologic criteria

Natalie Turner, Hui-Li Wong, Arnoud Templeton, Sagarika Tripathy, Te Whiti Rogers, Matthew Croxford, Ian Jones, Mathuranthakan Sinnathamby, Jayesh Desai, Jeanne Tie, Susie Bae, Michael Christie, Peter Gibbs, Ben Tran

Journal article  |  2016  |  International Journal of Cancer

Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer

Rosemary Millen, Jordane Malaterre, Ryan S Cross, Sandra Carpinteri, Jayesh Desai, Ben Tran, Phillip Darcy, Peter Gibbs, Oliver Sieber, Nikolajs Zeps, Paul Waring, Stephen Fox, Lloyd Pereira, Robert G Ramsay

Journal article  |  2016  |  OncoImmunology

Recurrence in patients with stage I colorectal cancer

Patrick Ely Teloken, David Ransom, Ian Faragher, Ian Jones, Peter Gibbs, Cameron Platell

Journal article  |  2016  |  ANZ Journal of Surgery

Multidisciplinary Management of Locally Advanced Rectal Cancer-An Evolving Landscape?

Margaret Lee, Peter Gibbs, Rachel Wong

Journal article  |  2015  |  Clinical Colorectal Cancer

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer

Scott Kopetz, Jayesh Desai, Emily Chan, Joel Randolph Hecht, Peter J O'Dwyer, Dipen Maru, Morris Van, Filip Janku, Arvind Dasari, Woonbook Chung, Jean-Pierre J Issa, Peter Gibbs, Brian James, Garth Powis, Keith B Nolop, Suman Bhattacharya, Leonard Saltz

Journal article  |  2015  |  Journal of Clinical Oncology

SIRFLOX: RANDOMISED PHASE III TRIAL COMPARING FIRST-LINE MFOLFOX6 /- BEVACIZUMAB (BEV) VERSUS MFOLFOX6 /- BEV plus SELECTIVE INTERNAL RADIATION THERAPY (SIRT) IN PATIENTS WITH METASTATIC COLORECTAL CANCER (MCRC) - ANALYSIS BY PRESENCE OR ABSENCE OF EXTRA-HEPATIC METASTASES, BEV TREATMENT AND SITE OF FIRST PROGRESSION

Peter Gibbs, Guy A van Hazel, Volker Heinemann, Navesh K Sharma, Michael PN Findlay, Jens Ricke, Marc Peeters, David Perez, Bridget Robinson, Andrew Strickland, Tom Ferguson, Javier Rodrigez, Hendrik Kroening, Ido Wolf, Vinod Ganju, Euan Walpole, Eveline Boucher, Thomas Tichler, Val Gebski, Mark Van Buskirk

Conference Proceedings  |  2015  |  Asia-Pacific Journal of Clinical Oncology

SMOKING AND THE INFLUENCE OF BEHAVIOURAL FACTORS IN THE OUTCOMES OF PATIENTS WITH COLON CANCER

Rachel Delahunty, Julie Johns, Michael Harold, Peter Gibbs

Conference Proceedings  |  2015  |  Asia-Pacific Journal of Clinical Oncology

Phase II trial of selective internal radiation therapy and systemic chemotherapy for liver-predominant metastases from pancreatic adenocarcinoma

Peter Gibbs, Cuong Do, Lara Lipton, David N Cade, Michael J Tapner, David Price, Geoff D Bower, Richard Dowling, Meir Lichtenstein, Guy A van Hazel

Journal article  |  2015  |  BMC Cancer

Patterns of care for metastatic renal cell carcinoma in Australia

Daphne Day, Yada Kanjanapan, Edmond Kwan, Desmond Yip, Nathan Lawrentschuk, Miles Andrews, Ian D Davis, Arun A Azad, Mark Rosenthal, Shirley Wong, Alice Johnstone, Peter Gibbs, Ben Tran

Journal article  |  2015  |  BJU International

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer

Robert N Jorissen, Michael Christie, Dmitri Mouradov, Anuratha Sakthianandeswaren, Shan Li, Christopher Love, Zheng-Zhou Xu, Peter L Molloy, Ian T Jones, Stephen McLaughlin, Robyn L Ward, Nicholas J Hawkins, Andrew R Ruszkiewicz, James Moore, Antony W Burgess, Dana Busam, Qi Zhao, Robert L Strausberg, Lara Lipton, Jayesh Desai, et al.

Journal article  |  2015  |  British Journal of Cancer

Novel quality indicators for metastatic colorectal cancer management identify significant variations in these measures across treatment centers in Australia

Natalie Heather Turner, Hui-li Wong, Kathryn Field, Rachel Wong, Jeremy Shapiro, Desmond Yip, Louise Nott, Jeanne Tie, Suzanne Kosmider, Ben Tran, Jayesh Desai, Joseph McKendrick, Allan Zimet, Gary Richardson, Mahesh Iddawela, Peter Gibbs

Journal article  |  2015  |  Asia-Pacific Journal of Clinical Oncology

Patterns of care and outcomes for elderly patients with metastatic colorectal cancer in Australia

Sagun Parakh, Hui-Li Wong, Rajat Rai, Sayed Ali, Kathryn Field, Jeremy Shapiro, Rachel Wong, Louise Nott, Peter Gibbs, Desmond Yip

Journal article  |  2015  |  Journal of Geriatric Oncology

Primary Tumor Resection in Patients With Metastatic Colorectal Cancer Is Associated With Reversal of Systemic Inflammation and Improved Survival

Natalie Turner, Ben Tran, Phillip V Tran, Mathuranthakan Sinnathamby, Hui-Li Wong, Ian Jones, Matthew Croxford, Jayesh Desai, Jeanne Tie, Kathryn Maree Field, Suzanne Kosmider, Susie Bae, Peter Gibbs

Journal article  |  2015  |  Clinical Colorectal Cancer

RE: Aspirin and COX-2 Inhibitor Use in Patients With Stage III Colon Cancer

Margaret Lee, Peter Gibbs

Journal article  |  2015  |  JNCI Journal of the National Cancer Institute

Less Surgery, Improved Survival From Stage IV Colorectal Cancer?

Rachel Wong, Peter Gibbs

Journal article  |  2015  |  JAMA Surgery

Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer

J Tie, I Kinde, Y Wang, HL Wong, J Roebert, M Christie, M Tacey, R Wong, M Singh, CS Karapetis, J Desai, B Tran, RL Strausberg, LA Diaz, N Papadopoulos, KW Kinzler, B Vogelstein, P Gibbs

Journal article  |  2015  |  Annals of Oncology

Problematic Use of Multiple Subgroup Analyses in Assessing the Impact of Aspirin in Prostate Cancer

Margaret Lee, Hui-Li Wong, Peter Gibbs

Journal article  |  2015  |  Journal of Clinical Oncology

Comparing Oncological Outcomes of Laparoscopic Versus Open Surgery for Colon Cancer: Analysis of a Large Prospective Clinical Database

T Sammour, Ian T Jones, P Gibbs, R Chandra, Malcolm C Steel, Susan M Shedda, M Croxford, I Faragher, Ian P Hayes, Ian A Hastie

Journal article  |  2015  |  Journal of Surgical Oncology

SIRFLOX: Randomized phase III trial comparing first-line mFOLFOX6 /- bevacizumab (bev) versus mFOLFOX6 selective internal radiation therapy (SIRT) /- bev in patients (pts) with metastatic colorectal cancer (mCRC).

Peter Gibbs, Volker Heinemann, Navesh K Sharma, Michael PN Findlay, Jens Ricke, Val Gebski, Mark Van Buskirk, Guy A Van Hazel

Conference Proceedings  |  2015  |  Journal of Clinical Oncology

Association between type 2 diabetes mellitus (T2DM), diabetic therapies and clinical outcomes in patients (pts) with metastatic colorectal cancer (mCRC).

Natalie Heather Turner, Hui-li Wong, Margaret Lee, Soe Yu Aung, Rajat Rai, Claire Maddison, Louise M Nott, Desmond Yip, Kortnye Morris, Kathryn M Field, Jeremy David Shapiro, Suzanne Kosmider, Rachel Wong, Lara Rachel Lipton, Jeremy David Power, Susie Bae, Allan Solomon Zimet, Peter Gibbs

Conference Proceedings  |  2015  |  Journal of Clinical Oncology

Impact of primary tumor stage on survival following resection of metachronous liver and/or lung metastases in colorectal cancer

Hui-Li Wong, Vishal Boolell, Suzanne Kosmider, Kathryn Maree Field, Rachel Wong, Jeremy David Shapiro, Prasad Cooray, Ian Hayes, Ian Faragher, Malcolm Steel, Peter Gibbs

Conference Proceedings  |  2015  |  Journal of Clinical Oncology

Gastrointestinal perforation in metastatic colorectal cancer patients with peritoneal metastases receiving bevacizumab

Aflah Roohullah, Hui-Li Wong, Katrin M Sjoquist, Peter Gibbs, Kathryn Field, Ben Tran, Jeremy Shapiro, Joe Mckendrick, Desmond Yip, Louise Nott, Val Gebski, Weng Ng, Wei Chua, Timothy Price, Niall Tebbutt, Lorraine Chantrill

Journal article  |  2015  |  World Journal of Gastroenterology

Risk-Adjusted Pathologic Margin Positivity Rate: A Problematic Quality Indicator

Natalie H Turner, Hui-Li Wong, Peter Gibbs

Journal article  |  2015  |  Journal of Clinical Oncology

Radioembolization for hepatocellular carcinoma: current role and future directions - the medical oncologist's perspective

Peter Gibbs, Jeanne Tie, Lourens Bester

Journal article  |  2015  |  Hepatic Oncology

Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation

Nishi Kothari, Richard Kim, Robert N Jorissen, Jayesh Desai, Jeanne Tie, Hui-Li Wong, Ian Farragher, Ian Jones, Fiona L Day, Shan Li, Anuratha Sakthinandeswaren, Michelle Palmieri, Lara Lipton, Michael Schell, Jamie K Teer, David Shibata, Timothy Yeatman, Oliver M Sieber, Peter Gibbs, Ben Tran

Journal article  |  2015  |  Acta Oncologica

Blood-Based Protein Biomarker Panel for the Detection of Colorectal Cancer

Kim YC Fung, Bruce Tabor, Michael J Buckley, Ilka K Priebe, Leanne Purins, Celine Pompeia, Gemma V Brierley, Trevor Lockett, Peter Gibbs, Jeanne Tie, Paul McMurrick, James Moore, Andrew Ruszkiewicz, Edouard Nice, Timothy E Adams, Antony Burgess, Leah J Cosgrove

Journal article  |  2015  |  PLOS ONE

Can neutrophil-to-lymphocyte ratio be used to identify patients with metastatic renal cell carcinoma who may gain greater benefit from cytoreductive nephrectomy?

Daphne Dai, Yada Kanjanapan, Edmond Michael Kwan, Desmond Yip, Nathan Lawrentschuk, Ian D Davis, Arun Azad, Mark Rosenthal, Shams Ul Arifeen, Mahmood Alam, Peter Gibbs, Ben Tran

Conference Proceedings  |  2015  |  Journal of Clinical Oncology

Outcomes in the surgical treatment of low rectal cancer: does neoadjuvant treatment equalize results?

William G Pollett, Peter Gibbs, Stephen McLaughlin, Jimmy Eteuati, Michael Harold, Kaye Marion, Shweta Patel, Ian Jones

Journal article  |  2015  |  ANZ Journal of Surgery

A mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer

Fiona Day, Andrea Muranyi, Shalini Singh, Kandavel Shanmugam, David Williams, David Byrne, Kym Pham, Michelle Palmieri, Jeanne Tie, Thomas Grogan, Peter Gibbs, Oliver Sieber, Paul Waring, Jayesh Desai

Journal article  |  2015  |  Targeted Oncology

Treatment and outcomes of metastatic colorectal cancer in Australia: defining differences between public and private practice

K Field, J Shapiro, H-L Wong, M Tacey, L Nott, B Tran, N Turner, S Ananda, G Richardson, R Jennens, R Wong, J Power, M Burge, P Gibbs

Journal article  |  2015  |  Internal Medicine Journal

Comparison of ECOG/WHO Performance Status and ASA Score as a Measure of Functional Status

Jane Young, Tim Badgery-Parker, Timothy Dobbins, Mikaela Jorgensen, Peter Gibbs, Ian Faragher, Ian Jones, David Currow

Journal article  |  2015  |  Journal of Pain and Symptom Management

Effect of DNA-PK dependent phosphorylation of topo-I-S10 on its rate of proteasomal degradation and CPT response.

Ankur K Shah, Vibhu Sachdew, Julian Taylor-Parker, Umit Tapan, Yara Hamade Tohme, Yevgeniya Malinkovich, Ben Tran, Peter Gibbs, Ravi Salgia, Forest M White, Jeffrey Parvin, Ajit Bharti

Conference Proceedings  |  2015  |  Journal of Clinical Oncology

Survival impact of adjuvant chemotherapy for resected early-stage rectal adenocarcinoma.

Rebecca Yin Tay, Murtaza Jamnagerwalla, Malcolm Steel, Hui-Li Wong, Joseph James McKendrick, Ian Faragher, Suzanne Kosmider, Ian Hastie, Jayesh Desai, Peter Gibbs, Rachel Wong

Conference Proceedings  |  2015  |  Journal of Clinical Oncology

Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients

Susie Bae, Hui-Li Wong, Jeanne Tie, Jayesh Desai, Kathryn Field, Suzanne Kosmider, Spiros Fourlanos, Ian Jones, Iain Skinner, Peter Gibbs

Journal article  |  2015  |  Journal of Cancer Epidemiology

Early detection of cancer: past, present, and future.

Joshua D Schiffman, Paul G Fisher, Peter Gibbs

Journal article  |  2015  |  American Society of Clinical Oncology Educational Book

Screening in both healthy and high-risk populations offers the opportunity to detect cancer early and with an increased opportunit..

Current opinion on optimal systemic treatment for metastatic colorectal cancer: outcome of the ACTG/AGITG expert meeting ECCO 2013

Timothy J Price, Eva Segelov, Matthew Burge, Daniel G Haller, Niall C Tebbutt, Christos S Karapetis, Cornelis JA Punt, Nick Pavlakis, Dirk Arnold, Peter Gibbs, Jeremy D Shapiro

Journal article  |  2014  |  Expert Review of Anticancer Therapy

Translation of clinical trial outcomes to metastatic colorectal cancer patients in community practice

Sheau Wen Lok, Hui-li Wong, Suzanne Kosmider, Kathryn Field, Jeanne Tie, Jayesh Desai, Susie Bae, Mark Tacey, Iain Skinner, Ian Jones, Peter Gibbs

Journal article  |  2014  |  Asia Pacific Journal of Clinical Oncology

Selective Internal Radiation Therapy (SIRT) with yttrium-90 resin microspheres plus standard systemic chemotherapy regimen of FOLFOX versus FOLFOX alone as first-line treatment of non-resectable liver metastases from colorectal cancer: the SIRFLOX study

Peter Gibbs, Val Gebski, Mark Van Buskirk, Kenneth Thurston, David N Cade, Guy A Van Hazel

Journal article  |  2014  |  BMC Cancer

Survival, mortality and morbidity outcomes after oesophagogastric cancer surgery in New South Wales, 2001-2008 REPLY

Nicola Creighton, Ross C Smith, David C Currow

Journal article  |  2014  |  Medical Journal of Australia

Survival, mortality and morbidity outcomes after oesophagogastric cancer surgery in New South Wales, 2001-2008

Margaret Lee, Peter Gibbs

Journal article  |  2014  |  Medical Journal of Australia

The role of tissue diagnosis prior to neoadjuvant chemoradiotherapy for locally advanced rectal cancer

ES Daniel, P Gibbs, M Guerrieri, I Faragher

Journal article  |  2014  |  Colorectal Disease

Serious hepatic complications of selective internal radiation therapy with yttrium-90 microsphere radioembolization for unresectable liver tumors

James C Kuo, Andrea Tazbirkova, Robert Allen, Suzanne Kosmider, Peter Gibbs, Desmond Yip

Journal article  |  2014  |  Asia-Pacific Journal of Clinical Oncology

Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer

Lise Lotte Christensen, Anja Holm, Juha Rantala, Olli Kallioniemi, Mads H Rasmussen, Marie S Ostenfeld, Frederik Dagnaes-Hansen, Bodil Oster, Troels Schepeler, Heidi Tobiasen, Kasper Thorsen, Oliver M Sieber, Peter Gibbs, Philippe Lamy, Torben F Hansen, Anders Jakobsen, Eva M Riising, Kristian Helin, Jan Lubinski, Rikke Hagemann-Madsen, et al.

Journal article  |  2014  |  PLoS One

Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H)

J Goldstein, B Tran, J Ensor, P Gibbs, HL Wong, SF Wong, E Vilar, J Tie, R Broaddus, S Kopetz, J Desai, MJ Overman

Journal article  |  2014  |  Annals of Oncology

A systematic review on the safety and efficacy of yttrium-90 radioembolization for unresectable, chemorefractory colorectal cancer liver metastases

Akshat Saxena, Lourens Bester, Leonard Shan, Marlon Perera, Peter Gibbs, Baerbel Meteling, David L Morris

Journal article  |  2014  |  Journal of Cancer Research and Clinical Oncology

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

Chetan Bettegowda, Mark Sausen, Rebecca J Leary, Isaac Kinde, Yuxuan Wang, Nishant Agrawal, Bjarne R Bartlett, Hao Wang, Brandon Luber, Rhoda M Alani, Emmanuel S Antonarakis, Nilofer S Azad, Alberto Bardelli, Henry Brem, John L Cameron, Clarence C Lee, Leslie A Fecher, Gary L Gallia, Peter Gibbs, Dung Le, et al.

Journal article  |  2014  |  Science Translational Medicine

Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution

Sally M Dewhurst, Nicholas McGranahan, Rebecca A Burrell, Andrew J Rowan, Eva Groenroos, David Endesfelder, Tejal Joshi, Dmitri Mouradov, Peter Gibbs, Robyn L Ward, Nicholas J Hawkins, Zoltan Szallasi, Oliver M Sieber, Charles Swanton

Journal article  |  2014  |  Cancer Discovery

PIK3CA, BRAF, and PTEN Status and Benefit from Cetuximab in the Treatment of Advanced Colorectal Cancer-Results from NCIC CTG/AGITG CO.17

Christos S Karapetis, Derek Jonker, Manijeh Daneshmand, Jennifer E Hanson, Christopher J O'Callaghan, Celia Marginean, John R Zalcberg, John Simes, Malcolm J Moore, Niall C Tebbutt, Timothy J Price, Jeremy D Shapiro, Nick Pavlakis, Peter Gibbs, Guy A Van Hazel, Ursula Lee, Rashida Haq, Shakeel Virk, Dongsheng Tu, Ian AJ Lorimer

Journal article  |  2014  |  Clinical Cancer Research

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours

Jerome Galon, Bernhard Mlecnik, Gabriela Bindea, Helen K Angell, Anne Berger, Christine Lagorce, Alessandro Lugli, Inti Zlobec, Arndt Hartmann, Carlo Bifulco, Iris D Nagtegaal, Richard Palmqvist, Giuseppe V Masucci, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Michele Maio, Luigi Laghi, Fabio Grizzi, Martin Asslaber, et al.

Journal article  |  2014  |  Journal of Pathology

Second primary colorectal cancer in the era of prevalent screening and imaging

Susie Bae, Muslim Asadi, Ian Jones, Stephen McLaughlin, Andrew Bui, Malcolm Steele, Jeanne Tie, Peter Gibbs

Journal article  |  2013  |  ANZ Journal of Surgery

Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study

Jiping Wang, Luis G Carvajal-Carmona, Jen-Hwa Chu, Ann G Zauber, Michikai Kubo, Koichi Matsuda, Malcolm Dunlop, Richard S Houlston, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Mark J Ratain, Yusuke Nakamura, Scott T Weiss, Ian Tomlinson, Monica M Bertagnolli

Journal article  |  2013  |  Clinical Cancer Research

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

Dmitri Mouradov, Enric Domingo, Peter Gibbs, Robert N Jorissen, Shan Li, Pik Ying Soo, Lara Lipton, Jayesh Desai, Havard E Danielsen, Dahmane Oukrif, Marco Novelli, Christopher Yau, Christopher C Holmes, Ian T Jones, Stephen McLaughlin, Peter Molloy, Nicholas J Hawkins, Robyn Ward, Rachel Midgely, David Kerr, et al.

Journal article  |  2013  |  American Journal of Gastroenterology

Developing a national database for metastatic colorectal cancer management: perspectives and challenges

K Field, H-L Wong, J Shapiro, S Kosmider, J Tie, S Bae, D Yip, J McKendrick, L Nott, J Desai, M Harold, L Lipton, G Stefanou, L Lim, P Parente, P Gibbs

Journal article  |  2013  |  Internal Medicine Journal

Study design of ASPirin in Reducing Events in the Elderly (ASPREE): A randomized, controlled trial

RH Grimm, JJ McNeil, W Applegate, L Beilin, S Espinoza, C Johnston, B Kirpach, K Margolis, A Murray, MR Nelson, CM Reid, R Shah, E Storey, AM Tonkin, P Wilson, R Wolfe, RL Woods, W Abhayaratna, D Ames, L Cobiac, et al.

Journal article  |  2013  |  Contemporary Clinical Trials

CHemotherapy in older adults with colorectal cancer

C Maddison, HL Wong, P Gibbs

Journal article  |  2013  |  Cancer Forum

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/beta-catenin signalling thresholds for tumourigenesis

M Christie, RN Jorissen, D Mouradov, A Sakthianandeswaren, S Li, F Day, C Tsui, L Lipton, J Desai, IT Jones, S McLaughlin, RL Ward, NJ Hawkins, AR Ruszkiewicz, J Moore, AW Burgess, D Busam, Q Zhao, RL Strausberg, AJ Simpson, et al.

Journal article  |  2013  |  Oncogene

Pharmaco-economic analysis of direct medical costs of metastatic colorectal cancer therapy with XELOX or modified FOLFOX-6 regimens: Implications for health-care utilization in Australia

Giao Tran, Stephen P Hack, Annette Kerr, Leanne Stokes, Peter Gibbs, Timothy Price, Carlene Todd

Journal article  |  2013  |  Asia Pacific Journal of Clinical Oncology

Financial Incentives in Cancer Care and Impact on Prescribing Practice

Hui-li Wong, Kathryn M Field, Jeremy D Shapiro, Joseph J McKendrick, Peter Gibbs

Journal article  |  2013  |  Journal of Clinical Oncology

Co-funded expanded access programmes for new oncology drugs: creating a two-tier system for Australian cancer patients? Reply

J Tie, P Gibbs

Journal article  |  2013  |  Internal Medicine Journal

MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer

Lise Lotte Christensen, Heidi Tobiasen, Anja Holm, Troels Schepeler, Marie S Ostenfeld, Kasper Thorsen, Mads H Rasmussen, Karin Birkenkamp-Demtroeder, Oliver M Sieber, Peter Gibbs, Jan Lubinski, Philippe Lamy, Soren Laurberg, Bodil Oster, Kristian Q Hansen, Rikke Hagemann-Madsen, Kristina Byskov, Torben F Orntoft, Claus L Andersen

Journal article  |  2013  |  International Journal of Cancer

PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer

Fiona L Day, Robert N Jorissen, Lara Lipton, Dmitri Mouradov, Anuratha Sakthianandeswaren, Michael Christie, Shan Li, Cary Tsui, Jeannie Tie, Jayesh Desai, Zheng-Zhou Xu, Peter Molloy, Vicki Whitehall, Barbara A Leggett, Ian T Jones, Stephen McLaughlin, Robyn L Ward, Nicholas J Hawkins, Andrew R Ruszkiewicz, James Moore, et al.

Journal article  |  2013  |  Clinical Cancer Research

Clinical trial participation and outcome for patients with glioblastoma: Multivariate analysis from a comprehensive dataset

Kathryn M Field, Katharine J Drummond, Merve Yilmaz, Mark Tacey, Daniel Compston, Peter Gibbs, Mark A Rosenthal

Journal article  |  2013  |  Journal of Clinical Neuroscience

Association of hypomagnesemia with inferior survival in a phase III, randomized study of cetuximab plus best supportive care versus best supportive care alone: NCIC CTG/AGITG CO.17

MM Vickers, CS Karapetis, D Tu, CJ O'Callaghan, TJ Price, NC Tebbutt, G Van Hazel, JD Shapiro, N Pavlakis, P Gibbs, J Blondal, U Lee, JM Meharchand, RL Burkes, SH Rubin, J Simes, JR Zalcberg, MJ Moore, L Zhu, DJ Jonker

Journal article  |  2013  |  Annals of Oncology

An Australian translational Study to evaluate the prognostic role of inflammatory markers in patients with metastatic ColorEctal caNcer Treated with bevacizumab (Avastin (TM)) [ASCENT]

Stephen Clarke, Matt Burge, Cassandra Cordwell, Peter Gibbs, William Reece, Niall Tebbutt

Journal article  |  2013  |  BMC Cancer

A phase I trial of imatinib in combination with mFOLFOX6-bevacizumab in patients with advanced colorectal cancer

M Michael, J Zalcberg, P Gibbs, L Lipton, M Gouillou, M Jefford, G McArthur, M Copeman, K Lynch, NC Tebbutt

Journal article  |  2013  |  CANCER CHEMOTHERAPY AND PHARMACOLOGY

Overview of biomarkers in metastatic colorectal cancer: Tumour, blood and patient-related factors

Stephen J Clarke, Christos S Karapetis, Peter Gibbs, Nick Pavlakis, Jayesh Desai, Michael Michael, Niall C Tebbutt, Tim J Price, Josep Tabernero

Journal article  |  2013  |  Critical Reviews in Oncology Hematology

Does Adjuvant Chemotherapy in Elderly Patients With Stage III Colon Cancer Really Save Lives?

Hui-li Wong, Peter Gibbs

Journal article  |  2013  |  Journal of Clinical Oncology

Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

Axel Grothey, Eric Van Cutsem, Alberto Sobrero, Salvatore Siena, Alfredo Falcone, Marc Ychou, Yves Humblet, Olivier Bouche, Laurent Mineur, Carlo Barone, Antoine Adenis, Josep Tabernero, Takayuki Yoshino, Heinz-Josef Lenz, Richard M Goldberg, Daniel J Sargent, Frank Cihon, Lisa Cupit, Andrea Wagner, Dirk Laurent

Journal article  |  2013  |  The Lancet

SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer

Nicholas I Fleming, Robert N Jorissen, Dmitri Mouradov, Michael Christie, Anuratha Sakthianandeswaren, Michelle Palmieri, Fiona Day, Shan Li, Cary Tsui, Lara Lipton, Jayesh Desai, Ian T Jones, Stephen McLaughlin, Robyn L Ward, Nicholas J Hawkins, Andrew R Ruszkiewicz, James Moore, Hong-Jian Zhu, John M Mariadason, Antony W Burgess, et al.

Journal article  |  2013  |  CANCER RESEARCH

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

Neel Sengupta, Christopher Yau, Anuratha Sakthianandeswaren, Dmitri Mouradov, Peter Gibbs, Nirosha Suraweera, Jean-Baptiste Cazier, Guadalupe Polanco-Echeverry, Anil Ghosh, Mohamed Thaha, Shafi Ahmed, Roger Feakins, David Propper, Sina Dorudi, Oliver Sieber, Andrew Silver, Cecilia Lai

Journal article  |  2013  |  Molecular Cancer

Serum concentrations of brain-derived neurotrophic factor (BDNF) are decreased in colorectal cancer patients

GV Brierley, IK Priebe, L Purins, KYC Fung, B Tabor, T Lockett, E Nice, P Gibbs, J Tie, P McMurrick, J Moore, A Ruszkiewicz, A Burgess, LJ Cosgrove

Journal article  |  2013  |  Cancer Biomarkers

Treatment with unfunded drugs in oncology: the impact of access programmes and clinical trials

J Tie, P Gibbs

Journal article  |  2013  |  Internal Medicine Journal

Performance of serum lipocalin 2 as a diagnostic marker for colorectal cancer

Kim YC Fung, Ilka Priebe, Leanne Purins, Bruce Tabor, Gemma V Brierley, Trevor Lockett, Edouard Nice, Peter Gibbs, Jeannie Tie, Paul McMurrick, James Moore, Andrew Ruszkiewicz, Antony Burgess, Leah J Cosgrove

Journal article  |  2013  |  Cancer Biomarkers

Cancer classification using the Immunoscore: a worldwide task force

Jerome Galon, Franck Pages, Francesco M Marincola, Helen K Angell, Magdalena Thurin, Alessandro Lugli, Inti Zlobec, Anne Berger, Carlo Bifulco, Gerardo Botti, Fabiana Tatangelo, Cedrik M Britten, Sebastian Kreiter, Lotfi Chouchane, Paolo Delrio, Hartmann Arndt, Martin Asslaber, Michele Maio, Giuseppe V Masucci, Martin Mihm, et al.

Journal article  |  2012  |  Journal of Translational Medicine

An initial watch and wait approach is a valid strategy for selected patients with newly diagnosed metastatic colorectal cancer

M Voskoboynik, S Bae, S Ananda, J Desai, S Kosmider, P Gibbs

Journal article  |  2012  |  Annals of Oncology

Preliminary analysis of the cost-effectiveness of the National Bowel Cancer Screening Program: demonstrating the potential value of comprehensive real world data

B Tran, CL Keating, SS Ananda, S Kosmider, I Jones, M Croxford, KM Field, RC Carter, P Gibbs

Journal article  |  2012  |  Internal Medicine Journal

Microsatellite Instability Status Is Critical to Analysis of Survival in Stage II Colon Cancer

Susie Bae, Jeanne Tie, Jayesh Desai, Peter Gibbs

Journal article  |  2012  |  Journal of Clinical Oncology

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

Sarah L Spain, Luis G Carvajal-Carmona, Kimberley M Howarth, Angela M Jones, Zhan Su, Jean-Baptiste Cazier, Jennet Williams, Lauri A Aaltonen, Paul Pharoah, David J Kerr, Jeremy Cheadle, Li Li, Graham Casey, Pavel Vodicka, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, et al.

Journal article  |  2012  |  Human Molecular Genetics

Surgical oncology issues in locally advanced rectal cancer

Kevin Ooi, Peter Gibbs, Ian Faragher

Journal article  |  2011  |  ANZ Journal of Surgery

Impact of BRAF Mutation and Microsatellite Instability on the Pattern of Metastatic Spread and Prognosis in Metastatic Colorectal Cancer

Ben Tran, Scott Kopetz, Jeanne Tie, Peter Gibbs, Zhi-Qin Jiang, Christopher H Lieu, Atin Agarwal, Dipen M Maru, Oliver Sieber, Jayesh Desai

Journal article  |  2011  |  Cancer

Bending the Cost Curve in Cancer Care

Meghan Good, Chester B Good

Journal article  |  2011  |  New England Journal of Medicine

To the editor

K Field, I Faragher, P Gibbs

Journal article  |  2011  |  New England Journal of Medicine

Use of multiple reaction monitoring for multiplex analysis of colorectal cancer-associated proteins in human feces

Ching-Seng Ang, Julie Rothacker, Heather Patsiouras, Peter Gibbs, Antony W Burgess, Edouard C Nice

Journal article  |  2011  |  Electrophoresis

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

Ian PM Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma EM Jaeger, Susan Farrington, Annabelle Lewis, James GD Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, et al.

Journal article  |  2011  |  PLoS Genetics

Radioembolization in Combination with Systemic Chemotherapy as First-line Therapy for Liver Metastases from Colorectal Cancer

Suzanne Kosmider, Thean H Tan, Desmond Yip, Richard Dowling, Meir Lichtenstein, Peter Gibbs

Journal article  |  2011  |  Journal of Vascular and Interventional Radiology

PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis

Anuratha Sakthianandeswaren, Michael Christie, Carla D'Andreti, Cary Tsui, Robert N Jorissen, Shan Li, Nicholas I Fleming, Peter Gibbs, Lara Lipton, Jordane Malaterre, Robert G Ramsay, Toby J Phesse, Matthias Ernst, Rosemary E Jeffery, Richard Poulsom, Simon J Leedham, Stefania Segditsas, Ian PM Tomlinson, Oliver K Bernhard, Richard J Simpson, et al.

Journal article  |  2011  |  Cancer Research

BioGrid Australia Facilitates Collaborative Medical and Bioinformatics Research Across Hospitals and Medical Research Institutes by Linking Data from Diverse Disease and Data Types

Robert B Merriel, Peter Gibbs, Terence J O'Brien, Marienne Hibbert

Journal article  |  2011  |  Human Mutation

Optimizing targeted therapeutic development: analysis of a colorectal cancer patient population with the BRAF(V600E) mutation

Jeanne Tie, Peter Gibbs, Lara Lipton, Michael Christie, Robert N Jorissen, Antony W Burgess, Matthew Croxford, Ian Jones, Rachel Langland, Suzanne Kosmider, Daniel McKay, Gideon Bollag, Keith Nolop, Oliver M Sieber, Jayesh Desai

Journal article  |  2011  |  International Journal of Cancer

Lymph node yield following colorectal cancer surgery

Kathryn Field, Cameron Platell, Nicholas Rieger, Iain Skinner, David Wattchow, Ian Jones, Frank Chen, Suzanne Kosmider, Tony Wohlers, Marienne Hibbert, Peter Gibbs

Journal article  |  2011  |  ANZ Journal of Surgery

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

Jeanne Tie, Lara Lipton, Jayesh Desai, Peter Gibbs, Robert N Jorissen, Michael Christie, Katharine J Drummond, Benjamin NJ Thomson, Valery Usatoff, Peter M Evans, Adrian W Pick, Simon Knight, Peter WG Carne, Roger Berry, Adrian Polglase, Paul McMurrick, Qi Zhao, Dana Busam, Robert L Strausberg, Enric Domingo, et al.

Journal article  |  2011  |  Clinical Cancer Research

Comorbidity, age and overall survival in cetuximab-treated patients with advanced colorectal cancer (ACRC)-results from NCIC CTG CO.17: a phase III trial of cetuximab versus best supportive care

TR Asmis, E Powell, CS Karapetis, DJ Jonker, D Tu, M Jeffery, N Pavlakis, P Gibbs, L Zhu, D-A Dueck, R Whittom, C Langer, CJ O'Callaghan

Journal article  |  2011  |  Annals of Oncology

Hyaluronan-Irinotecan improves progression-free survival in 5-fluorouracil refractory patients with metastatic colorectal cancer: a randomized phase II trial

Peter Gibbs, Philip R Clingan, Vinod Ganju, Andrew H Strickland, Shirley S Wong, Niall C Tebbutt, Craig R Underhill, Richard M Fox, Steven P Clavant, Jenny Leung, Minh Pho, Tracey J Brown

Journal article  |  2011  |  Cancer Chemotherapy and Pharmacology

Guesstimates are not good enough for determining what is happening in routine care

V Heong, S Ananda, J Tie, P Gibbs

Journal article  |  2010  |  British Journal of Cancer

Predictors of clinic non-attendance: opportunities to improve patient outcomes in colorectal cancer

S Kosmider, S Shedda, IT Jones, S McLaughlin, P Gibbs

Journal article  |  2010  |  Internal Medicine Journal

Communication in and clinician satisfaction with multidisciplinary team meetings in neuro-oncology

KM Field, MA Rosenthal, J Dimou, M Fleet, P Gibbs, K Drummond

Journal article  |  2010  |  Journal of Clinical Neuroscience

Dose rounding of chemotherapy in colorectal cancer: An analysis of clinician attitudes and the potential impact on treatment costs

Kathryn Field, Anna Zelenko, Suzanne Kosmider, Karen Court, Li-Ling Ng, Marienne Hibbert, Peter Gibbs

Journal article  |  2010  |  Asia-Pacific Journal of Clinical Oncology

Linking data from hospital and cancer registry databases: should this be standard practice?

K Field, S Kosmider, J Johns, H Farrugia, I Hastie, M Croxford, M Chapman, M Harold, N Murigu, P Gibbs

Journal article  |  2010  |  Internal Medicine Journal

Adjuvant Chemotherapy Use Among Older Patients With Stage III Colon Cancer

Maggie Moore, Peter Gibbs

Journal article  |  2010  |  JAMA: Journal of the American Medical Association

Patient Comorbidities and Behaviour Once Diagnosed Are Major Contributors to Disparities in Cancer Health Outcomes

Maggie Moore, Jayesh Desai, Matthew Croxford, Kathryn Field, Ian Hastie, Peter Gibbs

Journal article  |  2010  |  Journal of Clinical Oncology

Caution Is Required Before Recommending Routine Carcinoembryonic Antigen and Imaging Follow-Up for Patients With Early-Stage Colon Cancer

Michael Chao, Peter Gibbs

Journal article  |  2009  |  Journal of Clinical Oncology

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

Robert N Jorissen, Peter Gibbs, Michael Christie, Saurabh Prakash, Lara Lipton, Jayesh Desai, David Kerr, Lauri A Aaltonen, Diego Arango, Mogens Kruhoffer, Torben F Orntoft, Claus Lindbjerg Andersen, Mike Gruidl, Vidya P Kamath, Steven Eschrich, Timothy J Yeatman, Oliver M Sieber

Journal article  |  2009  |  Clinical Cancer Research

Initial impact of Australia's National Bowel Cancer Screening Program

Sumitra S Ananda, Stephen J McLaughlin, Frank Chen, Ian P Hayes, Andrew A Hunter, Iain J Skinner, Malcolm CA Steel, Ian T Jones, Ian A Hastie, Nicholas A Rieger, Susan Shedda, Daniel J Compston, Peter Gibbs

Journal article  |  2009  |  Medical Journal of Australia

Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial

Nicole Mittmann, Heather-Jane Au, Dongsheng Tu, Christopher J O'Callaghan, Pierre K Isogai, Christos S Karapetis, John R Zalcberg, William K Evans, Malcolm J Moore, Jehan Siddiqui, Brian Findlay, Bruce Colwell, John Simes, Peter Gibbs, Matthew Links, Niall C Tebbutt, Derek J Jonker

Journal article  |  2009  |  Journal of the National Cancer Institute

Preoperative investigations for metastatic staging of colon and rectal cancer across multiple centres - what is current practice?

S Kosmider, DL Stella, K Field, M Moore, S Ananda, C Oakman, M Singh, P Gibbs

Journal article  |  2009  |  Colorectal Disease

Open-label phase I trial of vandetanib in combination with mFOLFOX6 in patients with advanced colorectal cancer

Michael Michael, Peter Gibbs, Robert Smith, Alex Godwood, Stuart Oliver, Niall Tebbutt

Journal article  |  2009  |  Investigational New Drugs

Impact of Body Mass Index on Colorectal Cancer Treatment and Outcomes: Need for Prospective and Comprehensive Data

Kathryn M Field, Matthew Croxford, Ian Hastie, Frank Chen, Suzanne Kosmider, Jayesh Desai, Peter Gibbs

Journal article  |  2009  |  Journal of Clinical Oncology

A Pilot Human Evaluation of a Formulation of Irinotecan and Hyaluronic Acid in 5-Fluorouracil-Refractory Metastatic Colorectal Cancer Patients

Peter Gibbs, Tracey J Brown, Raymond Ng, Ross Jennens, Edith Cinc, Minh Pho, Michael Michael, Richard M Fox

Journal article  |  2009  |  Chemotherapy

Response to "Disparities in the Use of Chemotherapy and Monoclonal Antibody Therapy for Elderly Advanced Colorectal Cancer Patients in the Community Oncology Setting"

Maggie Moore, Suzanne Kosmider, Kathryn Field, Jayesh Desai, Lionel Lim, Frances Barnett, Peter Gibbs

Journal article  |  2009  |  The Oncologist

DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal Cancers

Robert N Jorissen, Lara Lipton, Peter Gibbs, Matthew Chapman, Jayesh Desai, Ian T Jones, Timothy J Yeatman, Philip East, Ian PM Tomlinson, Hein W Verspaget, Lauri A Aaltonen, Mogens Kruhoffer, Torben F Orntoft, Claus Lindbjerg Andersen, Oliver M Sieber

Journal article  |  2008  |  Clinical Cancer Research

Re: Residual Treatment Disparities After Oncology Referral for Rectal Cancer

Kathryn M Field, Suzanne Kosmider, Jayesh Desai, Lionel C Lim, Frances S Barnett, Stephen McLaughlin, Ian T Jones, Peter Gibbs

Journal article  |  2008  |  Journal of the National Cancer Institute

Re: Residual Treatment Disparities After Oncology Referral for Rectal Cancer

Kathryn M Field, Suzanne Kosmider, Jayesh Desai, Lionel C Lim, Frances S Barnett, Stephen McLaughlin, Ian T Jones, Peter Gibbs

Journal article  |  2008  |  Journal of the National Cancer Institute

APER Rate Has Multiple Limitations as an Indicator of Quality in Rectal Cancer Surgery

Susan Shedda, Matthew Croxford, Ian Jones, Peter Gibbs

Journal article  |  2008  |  Annals of Surgery

Chemotherapy treatments for metastatic colorectal cancer: is evidence-based medicine in practice?

Kathryn M Field, Suzanne Kosmider, Michael Jefford, Ross Jennens, Michael Green, Peter Gibbs

Journal article  |  2008  |  Journal of Oncology Practice

Treatment options for colorectal cancer have expanded to include multiple oxaliplatin- and irinotecan-based regimens and more biol..

Successful Treatment of Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum with Radiation Therapy: Report of a Case

Marcus Foo, Michael WT Chao, Peter Gibbs, Michael Guiney, Rodney Jacobs

Journal article  |  2008  |  Diseases of the Colon and Rectum

Patient age and comorbidity are major determinants of adjuvant chemotherapy use for stage III colon cancer in routine clinical practice

Sumitra Ananda, Kathryn M Field, Suzanne Kosmider, Daniel Compston, Jayesh Desai, Lionel C Lim, Frances S Barnett, Ian T Jones, Iain Skinner, Peter Gibbs

Journal article  |  2008  |  Journal of Clinical Oncology

Towards establishing a national colorectal cancer database: Lessons learnt from Bio21 molecular medicine informatics model

Suzanne Kosmider, Ian Jones, Marienne Hibbert, Andrew Hunter, Steve McLaughlin, Julie Johns, Matthew Chapman, Peter Gibbs

Journal article  |  2008  |  ANZ Journal of Surgery

Colorectal cancer screening: ensuring benefits outweigh the risks

Suzanne Kosmider, Kathryn M Field, Finlay A Macrae, Peter Gibbs

Journal article  |  2008  |  Medical Journal of Australia

Long-term outcomes of patients with localized rectal cancer treated with chemoradiation or radiotherapy alone because of medical inoperability or patient refusal

L Lim, M Chao, J Shapiro, JL Millar, D Kipp, A Rezo, A Fong, IT Jones, S McLaughlin, P Gibbs

Journal article  |  2008  |  coloproctology

Feasibility of conducting a primary prevention trial of low-dose aspirin for major adverse cardiovascular events in older people in Australia: results from the ASPirin in Reducing Events in the Elderly (ASPREE) pilot study

Mark R Nelson, Christopher M Reid, David A Ames, Lawrence J Beilin, Geoffrey A Donnan, Peter Gibbs, Colin I Johnston, Henry Krum, Elsdon Storey, Andrew Tonkin, Rory Wolfe, Robyn Woods, John J McNeil

Journal article  |  2008  |  Medical Journal of Australia

Surveillance following treatment for colorectal cancer in Australia. Has best practice been adopted by medical oncologists?

S Kosmider, K Field, M Jefford, R Jennens, P Gibbs

Journal article  |  2008  |  Internal Medicine Journal

A critical review of the Glasgow prognostic score for colorectal cancer

Suzanne Kosmider, Ian Faragher, Ian Jones, Peter Gibbs

Journal article  |  2008  |  Annals of Surgery

Value of database linkage: are patients at risk of familial colorectal cancer being referred for genetic counselling and testing?

C Wong, P Gibbs, J Johns, I Jones, I Faragher, E Lynch, F Macrae, L Lipton

Journal article  |  2008  |  Internal Medicine Journal

Chemotherapy dosing strategies in the obese, elderly, and thin patient: results of a nationwide survey.

Kathryn M Field, Suzanne Kosmider, Michael Jefford, Michael Michael, Ross Jennens, Michael Green, Peter Gibbs

Journal article  |  2008  |  Journal of Oncology Practice

PURPOSE: Determining the optimal starting dose of chemotherapy (CHT) presents a considerable challenge when using body-surface are..

Single-institution experience of adjuvant 5-fluorouracil-based chemotherapy for stage III colon cancer

P Gibbs, D Handolias, S McLaughlin, M Chapman, J Johns, I Faragher

Journal article  |  2008  |  Internal Medicine Journal

Cytosine methylation profiling of cancer cell lines

Mathias Ehrich, Julia Turner, Peter Gibbs, Lara Lipton, Mara Giovanneti, Charles Cantor, Dirk van den Boom

Journal article  |  2008  |  Proceedings of the National Academy of Sciences of the United States of America

Anticoagulation prophylaxis for central venous catheter-associated thrombosis in cancer patients: An Australian perspective

Suzanne Kosmider, Kathryn M Field, Michael Jefford, Peter Gibbs

Journal article  |  2008  |  Asia-Pacific Journal of Clinical Oncology

A novel magnetic bead-based assay with high sensitivity and selectivity for analysis of telomerase in exfoliated cells from patients with bladder and colon cancer

Julie Rothacker, Robert G Ramsay, Daniel Ciznadija, Emma Gras, Craig B Neylon, Ngaire J Elwood, David Bouchier-Hayes, Peter Gibbs, Mark A Rosenthal, Edouard C Nice

Journal article  |  2007  |  Electrophoresis

The Molecular Medicine Informatics Model (MMIM)

M Hibbert, P Gibbs, T O'Brien, P Colman, R Merriel, N Rafael, M Georgeff

Journal article  |  2007  |  Studies in Health Technology and Informatics

Long-term outcomes of patients with localized rectal cancer treated with chemoradiation or radiotherapy alone because of medical inoperability or patient refusal

L Lim, M Chao, J Shapiro, JL Millar, D Kipp, A Rezo, A Fong, IT Jones, S McLaughlin, P Gibbs

Journal article  |  2007  |  Diseases of the Colon and Rectum

Optimizing the approach to patients with potentially resectable liver metastases from colorectal cancer

Elgene Lim, Benjamin NJ Thomson, Stefan Heinze, Michael Chao, Dishan Gunawardana, Peter Gibbs

Journal article  |  2007  |  ANZ Journal of Surgery

Comparing survival outcomes for patients with colorectal cancer treated in public and private hospitals

Niall C Tebbutt

Journal article  |  2007  |  Medical Journal of Australia

Comparing survival outcomes for patients with colorectal cancer treated in public and private hospitals

Suzanne Kosmider, Ian T Jones, Ian P Hayes, Peter Gibbs

Journal article  |  2007  |  Medical Journal of Australia

An incorrect diagnosis of metastatic colorectal cancer: The need for tissue diagnosis prior to treatment

Suzanne Kosmider, Peter Gibbs

Journal article  |  2007  |  Asia-Pacific Journal of Clinical Oncology

Type 2 Diabetes Mellitus, Smoking, and Colorectal Cancer

Peter Gibbs, Simone Steel, Steven McLaughlin, Ian Jones, Ian Faragher, Iain Skinner, Matthew Croxford, Julie Johns, Matthew Chapman, Lara Lipton

Journal article  |  2007  |  American Journal of Gastroenterology

Type 2 diabetes mellitus, smoking, and colorectal cancer

Peter Gibbs, Simone Steel, Steven McLaughlin, Ian Jones, Ian Faragher, Iain Skinner, Matthew Croxford, Julie Johns, Matthew Chapman, Lara Lipton

Journal article  |  2007  |  American Journal of Gastroenterology

Radioembolization of liver metastases from colorectal cancer using yttrium-90 microspheres with concomitant systemic oxaliplatin, fluorouracil, and leucovorin chemotherapy

Ricky A Sharma, Guy A Van Hazel, Bruno Morgan, David P Berry, Keith Blanshard, David Price, Geoffrey Bower, Jennifer A Shannon, Peter Gibbs, William P Steward

Journal article  |  2007  |  Journal of Clinical Oncology

Quality of pathology reporting impacts on lymph node yield in colon cancer

Nicholas A Rieger, Frances S Barnett, James WE Moore, Sumitra S Ananda, Matthew Croxford, Julie Johns, Peter Gibbs

Journal article  |  2007  |  Clinical Oncology

The Molecular Medicine Informatics Model (MMIM)

Marienne Hibbert, Peter Gibbs, Terence O'Brien, Peter Colman, Robert Merriel, Naomi Rafael, Michael Georgeff

Book Chapter  |  2007  |  Studies in Health Technology and Informatics

The Molecular Medicine Informatics Model (MMIM)

Marienne Hibbert, Peter Gibbs, Terence O'Brien, Peter Colman, Robert Merriel, Naomi Rafael, Michael Georgeff

Journal article  |  2007  |  Studies in Health Technology and Informatics

Re: Completion of therapy by medicare patients with stage III colon cancer

Peter Gibbs, Stephen McLaughlin, Iain Skinner, Ian Jones, Ian Hayes, Matthew Chapman, Julie Johns, Lionel Lim, Ian Faragher

Journal article  |  2006  |  Journal of the National Cancer Institute

Re: Completion of Therapy by Medicare Patients With Stage III Colon Cancer

Peter Gibbs, Stephen McLaughlin, Iain Skinner, Ian Jones, Ian Hayes, Matthew Chapman, Julie Johns, Lionel Lim, Ian Faragher

Journal article  |  2006  |  Journal of the National Cancer Institute

The influence of language spoken on colorectal cancer diagnosis and management

J Rodrigues, E Lim, S McLaughlin, I Faragher, I Skinner, M Chao, M Chapman, P Gibbs

Journal article  |  2006  |  ANZ Journal of Surgery

Acute arterial ischaemia secondary to multiple tumour emboli

BHC Le, DS Williams, P Gibbs

Journal article  |  2006  |  Internal Medicine Journal

Pancreatic cancer - current management.

Benjamin NJ Thomson, Simon W Banting, Peter Gibbs

Journal article  |  2006  |  Australian Family Physician

BACKGROUND: Pancreatic cancer remains a common and lethal cancer with a median survival of approximately 6 months. OBJECTIVE: This..

Preoperative chemoradiation for rectal cancer causes prolonged pudendal nerve terminal motor latency.

Jit F Lim, Joe J Tjandra, Richard Hiscock, Michael WT Chao, Peter Gibbs

Journal article  |  2006  |  Diseases of the Colon & Rectum

PURPOSE: A worsened anorectal function after chemoradiation for high-risk rectal cancer is often attributed to radiation damage of..

A prospective evaluation of treatment with Selective Internal Radiation Therapy (SIR-spheres) in patients with unresectable liver metastases from colorectal cancer previously treated with 5-FU based chemotherapy

L Lim, P Gibbs, D Yip, JD Shapiro, R Dowling, D Smith, A Little, W Bailey, M Liechtenstein

Journal article  |  2005  |  BMC CANCER

Squamous cell carcinoma arising in a giant condyloma acuminatum (Buschke-Lowenstein tumour).

Michael WT Chao, Peter Gibbs