Paul Ramsland

Draft genome of the bluefin tuna blood fluke, Cardicola forsteri

Lachlan Coff, Andrew J Guy, Bronwyn E Campbell, Barbara F Nowak, Paul A Ramsland, Nathan J Bott

Journal article  |  2022  |  PLOS ONE

The blood fluke Cardicola forsteri (Trematoda: Aporocotylidae) is a pathogen of ranched bluefin tuna in Japan and Australia. Genom..

Helicobacter pylori and the Role of Lipopolysaccharide Variation in Innate Immune Evasion.

Daniel Sijmons, Andrew J Guy, Anna K Walduck, Paul A Ramsland

Journal article  |  2022  |  Front Immunol

Helicobacter pylori is an important human pathogen that infects half the human population and can lead to significant clinical out..

Profiling the glycome of Cardicola forsteri, a blood fluke parasitic to bluefin tuna

Lachlan Coff, Jodie L Abrahams, Simon Collett, Cecilia Power, Barbara F Nowak, Daniel Kolarich, Nathan J Bott, Paul A Ramsland

Journal article  |  2022  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

Infections by blood flukes (Cardicola spp.) are considered the most significant health issue for ranched bluefin tuna, a major aqu..

Expression of monoclonal antibodies for functional and structural studies

V Irani, C Soliman, MA Raftis, AJ Guy, A Elbourne, PA Ramsland

Book Chapter  |  2022  |  Methods in Microbiology

Monoclonal antibodies are a mainstay of the research laboratory, with increasing focus on human IgG that best reflects the human a..

Combination of baicalein and trans-chalcone synergistically reduces amyloid beta and its toxicity in yeast

S Dhakal, IG Macreadie, B Adhikari, P Ramsland

Journal article  |  2021  |  Alzheimer's and Dementia

Background: There has been a long quest to uncover effective therapeutic strategy to prevent or cure AD as current strategies only..

Trans-Chalcone Plus Baicalein Synergistically Reduce Intracellular Amyloid Beta (A beta(42)) and Protect from A beta(42) Induced Oxidative Damage in Yeast Models of Alzheimer's Disease

Sudip Dhakal, Paul A Ramsland, Benu Adhikari, Ian Macreadie

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Finding an effective therapeutic to prevent or cure AD has been difficult due to the complexity of the brain and limited experimen..

Serum Anti-Carbohydrate Antibodies and Hyperacute Rejection

AJ Guy, PA Ramsland

Book Chapter  |  2021

Investigating virus-host cell interactions: Comparative binding forces between hepatitis C virus-like particles and host cell receptors in 2D and 3D cell culture models

Simon Collett, Joseph Torresi, Linda Earnest Silveira, Vi Khanh Truong, Dale Christiansen, Bang M Tran, Elizabeth Vincan, Paul A Ramsland, Aaron Elbourne

Journal article  |  2021  |  JOURNAL OF COLLOID AND INTERFACE SCIENCE

Cell cultures have been successfully used to study hepatitis C virus (HCV) for many years. However, most work has been done using ..

Effect of structural stability on endolysosomal degradation and T-cell reactivity of major shrimp allergen tropomyosin

Sandip D Kamath, Sandra Scheiblhofer, Christopher M Johnson, Yoan Machado, Thomas McLean, Aya C Taki, Paul A Ramsland, Swati Iyer, Isabella Joubert, Heidi Hofer, Michael Wallner, Josef Thalhamer, Jennifer Rolland, Robyn O'Hehir, Peter Briza, Fatima Ferreira, Richard Weiss, Andreas L Lopata

Journal article  |  2020  |  ALLERGY

Background Tropomyosins are highly conserved proteins, an attribute that forms the molecular basis for their IgE antibody cross‐re..

Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody

Caroline Soliman, Andrew J Guy, Jia Xin Chua, Mireille Vankemmelbeke, Richard S McIntosh, Sarah Eastwood, Vi Khanh Truong, Aaron Elbourne, Ian Spendlove, Lindy G Durrant, Paul A Ramsland

Journal article  |  2020  |  BIOCHEMICAL JOURNAL

Immunotherapy has been successful in treating many tumour types. The development of additional tumour-antigen binding monoclonal a..