Andrew Lawrence

Assessing methamphetamine-related cue reactivity in people with methamphetamine use disorder relative to controls

Alexandre A Guerin, Katherine D Drummond, Yvonne Bonomo, Andrew J Lawrence, Susan L Rossell, Jee Hyun Kim

Journal article  |  2021  |  ADDICTIVE BEHAVIORS

Methamphetamine use disorder involves methamphetamine-related cues invoking intense craving leading to relapse. Such cue reactivit..

Repeated, moderate footshock reduces the propensity to relapse to alcohol seeking in female, but not male, iP rats.

Erin J Campbell, Xavier J Maddern, Andrew J Lawrence

Journal article  |  2021  |  Behav Neurosci

Persistent alcohol use despite negative consequences is a key feature of alcohol use disorder (AUD) and is typically assessed usin..

N-acetylcysteine reduces addiction-like behaviour towards high-fat high-sugar food in diet-induced obese rats

Diana Sketriene, Damien Battista, Christina J Perry, Priya Sumithran, Andrew J Lawrence, Robyn M Brown

Journal article  |  2021  |  EUROPEAN JOURNAL OF NEUROSCIENCE

Compulsive forms of eating displayed by some obese individuals share similarities with compulsive drug-taking behaviour, a hallmar..

Muscarinic M-4 and M-5 receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol-preferring rats

Leigh C Walker, Kate L Huckstep, Nicola A Chen, Lexi J Hand, Craig W Lindsley, Christopher J Langmead, Andrew J Lawrence

Journal article  |  2021  |  BRITISH JOURNAL OF PHARMACOLOGY

BACKGROUND AND PURPOSE: Muscarinic acetylcholine receptors mediate alcohol consumption and seeking in rats. While M4 and M5 recept..

Mu-opioid receptors in septum mediate the development of behavioural sensitization to a single morphine exposure in male rats

Yu-Ling Li, Shoupeng Wei, Qing Liu, Qi Gong, Qing-Jie Zhang, Tian-Ge Zheng, Zheng Yong, Feng Chen, Andrew J Lawrence, Jian-Hui Liang

Journal article  |  2021  |  ADDICTION BIOLOGY

Behavioural sensitization (BS) is characterized by enhanced psychomotor responses to a dose of substance of abuse after prior repe..

The 5-HT2C receptor as a therapeutic target for alcohol and methamphetamine use disorders: A pilot study in treatment-seeking individuals

Erin J Campbell, Yvonne Bonomo, Adam Pastor, Lisa Collins, Amanda Norman, Peter Galettis, Janice Johnstone, Andrew J Lawrence

Journal article  |  2021  |  PHARMACOLOGY RESEARCH & PERSPECTIVES

Alcohol use disorder (AUD) and methamphetamine use disorder (MUD) are prevalent and have high adverse impacts on both the individu..

Genes and Cognitive Deficits in Adolescent-Onset Methamphetamine Use Disorder: Preliminary Evidence From a Cross-Sectional Study

Alexandre Guerin, Yvonne Bonomo, Kiymet Bozaoglu, Brian Dean, Andrew Lawrence, Michael Berk, Susan Rossell, Jee Hyun Kim

Conference Proceedings  |  2021  |  BIOLOGICAL PSYCHIATRY

Should we or shouldn't we? Preface to the Special Issue "Neurochemistry of Reward-Seeking"

Andrew J Lawrence

Journal article  |  2021  |  JOURNAL OF NEUROCHEMISTRY

Reward-seeking is critical for survival. Learning about the relationship between actions and outcomes helps us to make decisions a..

Reward Motivation and Cognitive Flexibility in Tau Null-Mutation Mice

Sara Oberrauch, Jeremy A Metha, Maddison L Brian, Samuel A Barnes, Travis J Featherby, Andrew J Lawrence, Daniel Hoyer, Carsten Murawski, Laura H Jacobson

Journal article  |  2021  |  Neurobiology of Aging

The reduction of tau or hyperphosphorylated tau (p-tau) has been proposed as a therapeutic strategy for Alzheimer's disease (AD) a..

New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies

Kirsten C Morley, Christina J Perry, Joshua Watt, Tristan Hurzeler, Lorenzo Leggio, Andrew J Lawrence, Paul Haber

Journal article  |  2021  |  EXPERT OPINION ON PHARMACOTHERAPY

introduction: The number of medications approved for AUD is small and they generally have limited efficacy. We need new pharmacoth..