Andrew Lawrence

Extinction and drug-induced reinstatement of cocaine seeking following self-administration or conditioned place preference in adolescent and adult rats

Alexandre A Guerin, Isabel C Zbukvic, Sophia J Luikinga, Katherine D Drummond, Andrew J Lawrence, Heather B Madsen, Jee Hyun Kim

Journal article  |  2020  |  Developmental Psychobiology

Adolescence marks a particularly vulnerable period to developing substance use disorders, and people who start using drugs in adol..

Adolescent chronic intermittent toluene inhalation dynamically regulates the transcriptome and neuronal methylome within the rat medial prefrontal cortex

Alec LW Dick, Qiongyi Zhao, Rose Crossin, Danay Baker-Andresen, Xiang Li, Janette Edson, Simone Roeh, Victoria Marshall, Timothy W Bredy, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2020  |  Addiction Biology

Inhalants containing the volatile solvent toluene are misused to induce euphoria or intoxication. Inhalant abuse is most common du..

New author guidelines and launch ofShort Reports

Andrew J Lawrence, Michael F Jarvis

Journal article  |  2020  |  Pharmacology Research & Perspectives

A review of tropical dry forest ecosystem service research in the Caribbean – gaps and policy-implications

HP Nelson, ES Devenish-Nelson, BL Rusk, M Geary, AJ Lawrence

Journal article  |  2020  |  Ecosystem Services

Brucine N-Oxide Reduces Ethanol Intake and Preference in Alcohol-Preferring Male Fawn-Hooded Rats

Shoupeng Wei, Yu-ling Li, Qi Gong, Hui Liang, Qing Liu, Rick E Bernardi, Han-Ting Zhang, Feng Chen, Andrew J Lawrence, Jian-hui Liang

Journal article  |  2020  |  Alcoholism: Clinical and Experimental Research

BACKGROUND: Alcohol use disorder places a heavy burden on global public health systems and thus is in urgent need of improved phar..

A sleeping giant: Suvorexant for the treatment of alcohol use disorder?

Erin J Campbell, Nathan J Marchant, Andrew J Lawrence

Journal article  |  2020  |  Brain Research

There are currently 3 FDA approved treatments for alcohol use disorder (AUD) in the USA, opioid receptor antagonists such as naltr..

Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents.

Leigh C Walker, Alice E Berizzi, Nicola A Chen, Patricia Rueda, Victoria M Perreau, Katherine Huckstep, Jirawoot Srisontiyakul, Piyarat Govitrapong, Jia Xiaojian, Craig W Lindsley, Carrie K Jones, Darren M Riddy, Arthur Christopoulos, Christopher J Langmead, Andrew J Lawrence

Journal article  |  2020  |  Biological Psychiatry

BACKGROUND: Alcohol use disorder (AUD) is a major socioeconomic burden on society, and current pharmacotherapeutic treatment optio..

Pattern of neural activation following yohimbine-induced reinstatement of alcohol seeking in rats

Leigh C Walker, Hanna E Kastman, Andrew J Lawrence

Journal article  |  2020  |  European Journal of Neuroscience

Alcohol use disorders represent an extensive socioeconomic burden, yet effective treatment options are suboptimal. A major hurdle ..

Suvorexant to treat alcohol use disorder and comorbid insomnia: Plan for a phase II trial

Erin J Campbell, Amanda Norman, Yvonne Bonomo, Andrew J Lawrence

Journal article  |  2020  |  Brain Research

Alcohol use disorder (AUD) is a complex neuropsychiatric disease state in which currently approved pharmacotherapeutics are of rel..

Allosteric modulation of muscarinic receptors in alcohol and substance use disorders.

Leigh C Walker, Andrew J Lawrence

Book Chapter  |  2020  |  Advances in Pharmacology

Alcohol and substance use disorders are chronic relapsing disorders, characterized by a compulsion to take drugs and loss of contr..

Interpretive nutrient profiling algorithms are a limited tool for assessing the healthiness of countries' packaged food and beverage supplies, and the conclusions are not substantiated by the data

Mark Lawrence, Anita Lawrence, Rosemary Stanton, Christina Pollard, Claire Pulker, Julie Woods, Bronwyn Ashton

Journal article  |  2019  |  Obesity Reviews

Cognition and Related Neural Findings on Methamphetamine Use Disorder: Insights and Treatment Implications From Schizophrenia Research

Alexandre A Guerin, Yvonne Bonomo, Andrew John Lawrence, Bernhard Theodor Baune, Eric J Nestler, Susan L Rossell, Jee Hyun Kim

Journal article  |  2019  |  Frontiers in Psychiatry

Chronic voluntary alcohol consumption causes persistent cognitive deficits and cortical cell loss in a rodent model

Annai J Charlton, Carlos May, Sophia J Luikinga, Emma L Burrows, Jee Hyun Kim, Andrew J Lawrence, Christina J Perry

Journal article  |  2019  |  Scientific Reports

Adolescent Vulnerability to Methamphetamine Use: Rodent and Human Findings

Jee Hyun Kim, Danni Jiang, Peter Hamilton, Christina Perry, Katherine Drummond, Kiymet Bozaoglu, Sophia Luikinga, Leonid Churilov, Yvonne Bonomo, Ross Bathgate, Eric Nestler, Susan Rossell, Andrew Lawrence, Alexandre Guerin

Conference Proceedings  |  2019  |  NEUROPSYCHOPHARMACOLOGY

Phenotyping neurons activated in the mouse brain during restoration of salt debt

Craig M Smith, Joshua Cross, Izel M Eraslan, Aparna Attawar, Sarah Ch'ng, Poshmaal Dhar, Rasika Samarasinghe, Laura Gray, Andrew J Lawrence

Journal article  |  2019  |  Journal of Chemical Neuroanatomy

Salt overconsumption contributes to hypertension, which is a major risk factor for stroke, heart and kidney disease. Characterisin..

Characterization of the relaxin family peptide receptor 3 system in the mouse bed nucleus of the stria terminalis

Sarah S Ch'ng, Jingjing Fu, Robyn M Brown, Craig M Smith, Mohammed Akhter Hossain, Stuart J McDougall, Andrew J Lawrence

Journal article  |  2019  |  Journal of Comparative Neurology

The bed nucleus of the stria terminalis (BNST) is a critical node involved in stress and reward-related behaviors. Relaxin family ..

The importance of sex differences in pharmacology research

Andrea Gogos, Christopher Langmead, Jennifer C Sullivan, Andrew J Lawrence

Journal article  |  2019  |  British Journal of Pharmacology

This article is part of a themed section on The Importance of Sex Differences in Pharmacology Research. To view the other articles..

A model of emotional stress-induced binge eating in female mice with no history of food restriction

Roberta G Anversa, Erin J Campbell, Sarah S Ch'ng, Andrea Gogos, Andrew J Lawrence, Robyn M Brown

Journal article  |  2019  |  Genes, Brain and Behavior

Overeating is a major contributing factor to obesity and related health complications. For women, in particular, negative emotions..

Environmental enrichment reduces the propensity to relapse following punishment-imposed abstinence of alcohol seeking

Erin J Campbell, Shubo Jin, Andrew J Lawrence

Journal article  |  2019  |  Physiology & Behavior

Environmental enrichment during periods of abstinence can reduce the risk of relapse to drug-seeking behavior. We trained rats to ..

The influence of opioid dependence on salt consumption and related psychological parameters in mice and humans

Craig M Smith, Joshua BB Garfield, Aparna Attawar, Dan I Lubman, Andrew J Lawrence

Journal article  |  2019  |  Drug and Alcohol Dependence

An imperfect model is still useful

Christina J Perry, Andrew J Lawrence

Journal article  |  2019  |  Addiction

GAL(3) receptor knockout mice exhibit an alcohol-preferring phenotype

Shannyn G Genders, Karlene J Scheller, Emily J Jaehne, Bradley J Turner, Andrew J Lawrence, Susanne M Brunner, Barbara Kofler, Maarten van den Buuse, Elvan Djouma

Journal article  |  2019  |  Addiction Biology

Galanin is a neuropeptide which mediates its effects via three G-protein coupled receptors (GAL1-3 ). Administration of a GAL3 ant..

Effects of Methamphetamine Exposure on Fear Learning and Memory in Adult and Adolescent Rats

Sophia J Luikinga, Christina J Perry, Heather B Madsen, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2019  |  Neurochemical Research

Methamphetamine (meth) use is often comorbid with anxiety disorders, with both conditions predominant during adolescence. Conditio..

The subfornical organ in sodium appetite: Recent insights

Sarah S Ch'ng, Andrew J Lawrence

Journal article  |  2019  |  Neuropharmacology

To maintain sodium homeostasis, animals will readily seek and ingest salt when salt-depleted, even at concentrations that they typ..

The effect of acute or repeated stress on the corticotropin releasing factor system in the CRH-IRES-Cre mouse: A validation study

Leigh C Walker, Lara C Cornish, Andrew J Lawrence, Erin J Campbell

Journal article  |  2019  |  Neuropharmacology

Corticotropin releasing factor (CRF) is a key component of stress responsivity, modulating related behaviors including anxiety and..

The effect of adolescent inhalant abuse on energy balance and growth

Rose Crossin, Ashleigh Qama, Zane B Andrews, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2019  |  Pharmacology Research & Perspectives

The role of the orexin (hypocretin) system in context-induced relapse to alcohol seeking

E Campbell, M Hill, N Marchant, A Lawrence

Conference Proceedings  |  2019  |  JOURNAL OF NEUROCHEMISTRY

The role of the orexin (hypocretin) system in context-induced relapse to alcohol seeking

E Campbell, M Hill, N Marchant, A Lawrence

Conference Proceedings  |  2019  |  JOURNAL OF NEUROCHEMISTRY

Kazuhiro Ikenaka (1952-2018) OBITUARY

Akio Wanaka, Andrew J Lawrence, Yukio Yoneda, Bernard Zalc, Alfreda Stadlin, Juana Maria Pasquini, Philip M Beart

Journal article  |  2019  |  Journal of Neurochemistry

A Neuroethics Framework for the Australian Brain Initiative

Adrian Carter, Linda J Richards

Journal article  |  2019  |  NEURON

Anterior Insular Cortex is Critical for the Propensity to Relapse Following Punishment-Imposed Abstinence of Alcohol Seeking

Erin J Campbell, Jeremy PM Flanagan, Leigh C Walker, Mitchell KR Hill, Nathan J Marchant, Andrew J Lawrence

Journal article  |  2019  |  The Journal of Neuroscience

Novel approaches to alcohol rehabilitation: Modification of stress-responsive brain regions through environmental enrichment

Terence Y Pang, Anthony J Hannan, Andrew J Lawrence

Journal article  |  2019  |  Neuropharmacology

Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies

R Crossin, AJ Lawrence, ZB Andrews, L Churilov, JR Duncan

Journal article  |  2019  |  Human & Experimental Toxicology

Altered body weight associated with substance abuse: a look beyond food intake

Rose Crossin, Andrew J Lawrence, Zane B Andrews, Jhodie R Duncan

Journal article  |  2019  |  Addiction Research & Theory

The intersection of stress and reward: BNST modulation of aversive and appetitive states

Sarah Ch'ng, Jingjing Fu, Robyn M Brown, Stuart J McDougall, Andrew J Lawrence

Journal article  |  2018  |  Progress in Neuro-Psychopharmacology and Biological Psychiatry

Glucose Availability Predicts the Feeding Response to Ghrelin in Male Mice, an Effect Dependent on AMPK in AgRP Neurons

Sarah H Lockie, Romana Stark, Mathieu Mequinion, Sarah Ch'ng, Dong Kong, David C Spanswick, Andrew J Lawrence, Zane B Andrews

Journal article  |  2018  |  Endocrinology

Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs

J-L Rault, AJ Lawrence, CR Ralph

Journal article  |  2018  |  Domestic Animal Endocrinology

The galanin receptor-3 antagonist, SNAP 37889, inhibits cue-induced reinstatement of alcohol-seeking and increases c-Fos expression in the nucleus accumbens shell of alcohol-preferring rats

Kira-Elise Wilson, Sigrid Limburg, Melissa K Duggan, Adam J Lawther, Spencer J Williams, Andrew J Lawrence, Matthew W Hale, Elvan Djouma

Journal article  |  2018  |  Journal of Psychopharmacology

CRITICAL ROLE FOR THE ANTERIOR INSULAR CORTEX IN THE PROPENSITY TO RELAPSE FOLLOWING PUNISHMENT-IMPOSED ABSTINENCE TO ALCOHOL SEEKING

EJ Campbell, J Flanagan, NJ Marchant, AJ Lawrence

Conference Proceedings  |  2018  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

ML375 A NOVEL NEGATIVE ALLOSTERIC MODULATOR (NAM) OF (M-5) MUSCARINIC RECEPTOR (MACHR) ATTENUATES ALCOHOL DRINKING AND SEEKING IN GENETICALLY SELECTED IP RATS THROUGH MODULATION OF DORSOLATERAL STRIATUM M5 RECEPTORS

AJ Lawrence, A Berizzi, CJ Perry, DM Shackleford, CW Lindsley, CK Jones, N Chen, PM Sexton, A Christopoulos, CJ Langmead

Conference Proceedings  |  2018  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Adolescent inhalant abuse induces an endocrine disorder analogous to adrenal insufficiency

Rose Crossin, Andrew J Lawrence, Brian Oldfield, Aneta Stefanidis, Zane B Andrews, Terence Pang, Jhodie R Duncan

Conference Proceedings  |  2018  |  CLINICAL ENDOCRINOLOGY

Muscarinic M-5 receptors modulate ethanol seeking in rats

Alice E Berizzi, Christina J Perry, David M Shackleford, Craig W Lindsley, Carrie K Jones, Nicola A Chen, Patrick M Sexton, Arthur Christopoulos, Christopher J Langmead, Andrew J Lawrence

Journal article  |  2018  |  Neuropsychopharmacology

New steps for treating alcohol use disorder

Erin J Campbell, Andrew J Lawrence, Christina J Perry

Journal article  |  2018  |  Psychopharmacology

A call to action for climate change research on Caribbean dry forests

HP Nelson, ES Devenish-Nelson, BL Rusk, M Geary, AJ Lawrence

Journal article  |  2018  |  Regional Environmental Change

Distinct Accumbens Shell Output Pathways Promote versus Prevent Relapse to Alcohol Seeking

Gabrielle D Gibson, Asheeta A Prasad, Philip Jean-Richard-dit-Bressel, Joanna OY Yau, E Zayra Millan, Yu Liu, Erin J Campbell, Jun Lim, Nathan J Marchant, John M Power, Simon Killcross, Andrew J Lawrence, Gavan P McNally

Journal article  |  2018  |  Neuron

Reduced alcohol-seeking in male offspring of sires exposed to alcohol self-administration followed by punishment-imposed abstinence

Erin J Campbell, Jeremy PM Flanagan, Nathan J Marchant, Andrew J Lawrence

Journal article  |  2018  |  Pharmacology Research & Perspectives

The persistence of growth impairments associated with adolescent inhalant abuse following sustained abstinence

Rose Crossin, Sheree Cairney, Andrew John Lawrence, Jhodie Rubina Duncan

Journal article  |  2018  |  Addiction Research & Theory

Salt Appetite, and the Influence of Opioids

Craig M Smith, Andrew J Lawrence

Journal article  |  2018  |  Neurochemical Research

Investigational drug therapies in phase I and phase II clinical trials for alcohol use disorders

Leigh C Walker, Andrew J Lawrence

Journal article  |  2018  |  Expert Opinion on Investigational Drugs

Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments

Rose Crossin, Zane B Andrews, Natalie A Sims, Terence Pang, Michael Mathai, Jonathan H Gooi, Aneta Stefanidis, Brian J Oldfield, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2018  |  Neuroendocrinology

Investigational drugs for alcohol use disorders: a review of preclinical data

Sarah S Ch'Ng, Andrew J Lawrence

Journal article  |  2018  |  Expert Opinion on Investigational Drugs

Nucleus incertus corticotrophin-releasing factor 1 receptor signalling regulates alcohol seeking in rats

Leigh C Walker, Hanna E Kastman, Jan A Koeleman, Craig M Smith, Christina J Perry, Elena V Krstew, Andrew L Gundlach, Andrew J Lawrence

Journal article  |  2017  |  Addiction Biology

Central amygdala relaxin-3/relaxin family peptide receptor 3 signalling modulates alcohol seeking in rats

Leigh C Walker, Hanna E Kastman, Elena V Krstew, Andrew L Gundlach, Andrew J Lawrence

Journal article  |  2017  |  British Journal of Pharmacology

Extinction of conditioned cues attenuates incubation of cocaine craving in adolescent and adult rats.

Heather B Madsen, Isabel C Zbukvic, Sophia J Luikinga, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2017  |  Neurobiology of Learning and Memory

Relapse to drug use is often precipitated by exposure to drug associated cues that evoke craving. Cue-induced drug craving has bee..

KCTD12 modulation of GABA(B) receptor function

Melody Li, Carol J Milligan, Haiyan Wang, Andrew Walker, Leonid Churilov, Andrew J Lawrence, Christopher A Reid, Seth C Hopkins, Steven Petrou

Journal article  |  2017  |  Pharmacology Research & Perspectives

Hurdles in Basic Science Translation

Christina J Perry, Andrew J Lawrence

Journal article  |  2017  |  Frontiers in Pharmacology

The galanin-3 receptor antagonist, SNAP 37889, suppresses alcohol drinking and morphine self-administration in mice

Karlene J Scheller, Spencer J Williams, Andrew J Lawrence, Elvan Djouma

Journal article  |  2017  |  Neuropharmacology

Aripiprazole Facilitates Extinction of Conditioned Fear in Adolescent Rats

Despina E Ganella, Liubov Lee-Kardashyan, Sophia J Luikinga, Danny LD Nguyen, Heather B Madsen, Isabel C Zbukvic, Russell Coulthard, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2017  |  Frontiers in Behavioral Neuroscience

Addiction-like Synaptic Impairments in Diet-Induced Obesity

Robyn Mary Brown, Yonatan Michael Kupchik, Sade Spencer, Constanza Garcia-Keller, David C Spanswick, Andrew John Lawrence, Stephanie Elise Simonds, Danielle Joy Schwartz, Kelsey Ann Jordan, Thomas Clayton Jhou, Peter William Kalivas

Journal article  |  2017  |  Biological Psychiatry

MDMA-induced neurotoxicity of serotonin neurons involves autophagy and rilmenidine is protective against its pathobiology

Linda D Mercer, Gavin C Higgins, Chew L Lau, Andrew J Lawrence, Philip M Beart

Journal article  |  2017  |  Neurochemistry International

Prefrontal Dopaminergic Mechanisms of Extinction in Adolescence Compared to Adulthood in Rats

Isabel C Zbukvic, Chun Hui J Park, Despina E Ganella, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2017  |  Frontiers in Behavioral Neuroscience

CRF and the nucleus incertus: a node for integration of stress signals

Leigh C Walker, Andrew J Lawrence

Journal article  |  2017  |  Nature Reviews Neuroscience

Adolescent inhalant abuse leads to other drug use and impaired growth; implications for diagnosis

Rose Crossin, Sheree Cairney, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2017  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH

Reduced heart rate variability in pet dogs affected by anxiety-related behaviour problems

Dennis Wormald, Andrew J Lawrence, Gabrielle Carter, Andrew D Fisher

Journal article  |  2017  |  Physiology & Behavior

mGlu5 Signaling: A Target for Addiction Therapeutics?

Christina J Perry, M Foster Olive, Andrew J Lawrence

Book Chapter  |  2017

Addiction, cognitive decline and therapy: seeking ways to escape a vicious cycle

CJ Perry, AJ Lawrence

Journal article  |  2017  |  GENES BRAIN AND BEHAVIOR

The Role of Orexins/Hypocretins in Alcohol Use and Abuse

Leigh C Walker, Andrew J Lawrence

Book Chapter  |  2017  |  Current topics in behavioral neurosciences

Addiction is a chronic relapsing disorder characterized by compulsive drug seeking and drug taking despite negative consequences. ..

Role of Lateral Hypothalamic Orexin (Hypocretin) Neurons in Alcohol Use and Abuse: Recent Advances

LC Walker, SS Ch’ng, AJ Lawrence

Journal article  |  2016  |  Current Pharmacology Reports

The Nicotinic alpha 6-Subunit Selective Antagonist bPiDI Reduces Alcohol Self-Administration in Alcohol-Preferring Rats

Jirawoot Srisontiyakul, Hanna E Kastman, Elena V Krstew, Piyarat Govitrapong, Andrew J Lawrence

Journal article  |  2016  |  Neurochemical Research

Toluene inhalation in adolescent rats reduces flexible behaviour in adulthood and alters glutamatergic and GABAergic signalling

Teri M Furlong, Jhodie R Duncan, Laura H Corbit, Caroline D Rae, Benjamin D Rowlands, Anthony D Maher, Fatima A Nasrallah, Carol J Milligan, Steven Petrou, Andrew J Lawrence, Bernard W Balleine

Journal article  |  2016  |  Journal of Neurochemistry

Endogenous central amygdala mu-opioid receptor signaling promotes sodium appetite in mice

Craig M Smith, Lesley L Walker, Tanawan Leeboonngam, Michael J McKinley, Derek A Denton, Andrew J Lawrence

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Nucleus incertus Orexin(2) receptors mediate alcohol seeking in rats

Hanna E Kastman, Anna Blasiak, Leigh Walker, Marcin Siwiec, Elena V Krstew, Andrew L Gundlach, Andrew J Lawrence

Journal article  |  2016  |  Neuropharmacology

Knockdown of corticotropin-releasing factor 1 receptors in the ventral tegmental area enhances conditioned fear

Nicola A Chen, Despina E Ganella, Ross AD Bathgate, Alon Chen, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2016  |  European Neuropsychopharmacology

Analysis of correlations between early social exposure and reported aggression in the dog

Dennis Wormald, Andrew J Lawrence, Gabrielle Carter, Andrew D Fisher

Journal article  |  2016  |  Journal of Veterinary Behavior

Physiological stress coping and anxiety in greyhounds displaying inter-dog aggression

Dennis Wormald, Andrew J Lawrence, Gabrielle Carter, Andrew D Fisher

Journal article  |  2016  |  Applied Animal Behaviour Science

Validation of modified open field behaviour as a measure of trait anxiety in the dog

Dennis Wormald, Andrew J Lawrence, Gabrielle Carter, Andrew D Fisher

Journal article  |  2016  |  Applied Animal Behaviour Science

Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats

Isabel C Zbukvic, Despina E Ganella, Christina J Perry, Heather B Madsen, Christopher R Bye, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2016  |  CEREBRAL CORTEX

Orexin-1 receptor signalling in the prelimbic cortex and ventral tegmental area regulates cue-induced reinstatement of ethanol-seeking in iP rats

Robyn Mary Brown, Andrezza K Kim, Shaun Yon-Seng Khoo, Jee Hyun Kim, Bianca Jupp, Andrew John Lawrence

Journal article  |  2016  |  Addiction Biology

Metabotropic Glutamate 5 Modulators: Potential Agents for Treating Cocaine Addiction

CJ Perry, AJ Lawrence

Book Chapter  |  2016

Adenosine 2A receptors modulate reward behaviours for methamphetamine

Rose Chesworth, Robyn M Brown, Jee Hyun Kim, Catherine Ledent, Andrew J Lawrence

Journal article  |  2016  |  Addiction Biology

The metabotropic glutamate 5 receptor is necessary for extinction of cocaine-associated cues

Christina J Perry, Felicia Reed, Isabel C Zbukvic, Jee Hyun Kim, Andrew J Lawrence

Journal article  |  2016  |  BRITISH JOURNAL OF PHARMACOLOGY

Special Issue in Honour of Philip M Beart Foreword

Andrew J Lawrence, Andrew L Gundlach

Journal article  |  2016  |  Neurochemical Research

Fear extinction in 17 day old rats is dependent on metabotropic glutamate receptor 5 signaling

Despina E Ganella, Pushbalela Thangaraju, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2016  |  Behavioural Brain Research

Diet-induced obesity causes ghrelin resistance in reward processing tasks

Sarah H Lockie, Tara Dinan, Andrew J Lawrence, Sarah J Spencer, Zane B Andrews

Journal article  |  2015  |  Psychoneuroendocrinology

Chronic intermittent toluene inhalation in adolescent rats results in metabolic dysfunction with altered glucose homeostasis

ALW Dick, A Simpson, A Qama, Z Andrews, AJ Lawrence, JR Duncan

Journal article  |  2015  |  BRITISH JOURNAL OF PHARMACOLOGY

Relaxin-3 receptor (Rxfp3) gene deletion reduces operant sucrose-but not alcohol-responding in mice

AW Walker, CM Smith, AL Gundlach, AJ Lawrence

Journal article  |  2015  |  Genes, Brain and Behavior

NMDA receptor binding is reduced within mesocorticolimbic regions following chronic inhalation of toluene in adolescent rats

Alec Lindsay Ward Dick, Tine Pooters, Sarah Gibbs, Emma Giles, Ashleigh Qama, Andrew John Lawrence, Jhodie Rubina Duncan

Journal article  |  2015  |  Brain Research

Persistent variations in neuronal DNA methylation following cocaine self-administration and protracted abstinence in mice.

Danay Baker-Andresen, Qiongyi Zhao, Xiang Li, Bianca Jupp, Rose Chesworth, Andrew J Lawrence, Timothy Bredy

Journal article  |  2015  |  Neuroepigenetics

Continued vulnerability to relapse during abstinence is characteristic of cocaine addiction and suggests that drug-induced neuroad..

Involvement of central relaxin-3 signalling in sodium (salt) appetite

Craig M Smith, Lesley L Walker, Berenice E Chua, Michael J McKinley, Andrew L Gundlach, Derek A Denton, Andrew J Lawrence

Journal article  |  2015  |  EXPERIMENTAL PHYSIOLOGY

Distribution of the orexin-1 receptor ((OXR)-R-1.) in the mouse forebrain and rostral brainstem: A characterisation of OX1R-eGFP mice

Sarah Sulaiman Ch'ng, Andrew J Lawrence

Journal article  |  2015  |  Journal of Chemical Neuroanatomy

Experimental design and analysis and their reporting: new guidance for publication in BJP

Michael J Curtis, Richard A Bond, Domenico Spina, Amrita Ahluwalia, Stephen PA Alexander, Mark A Giembycz, Annette Gilchrist, Daniel Hoyer, Paul A Insel, Angelo A Izzo, Andrew J Lawrence, David J MacEwan, Lawrence DF Moon, Sue Wonnacott, Arthur H Weston, John C McGrath

Journal article  |  2015  |  BRITISH JOURNAL OF PHARMACOLOGY

Spatial Learning Requires mGlu5 Signalling in the Dorsal Hippocampus

Shawn Zheng Kai Tan, Despina E Ganella, Alec Lindsay Ward Dick, Jhodie R Duncan, Emma Ong-Palsson, Ross AD Bathgate, Jee Hyun Kim, Andrew J Lawrence

Journal article  |  2015  |  Neurochemical Research

Extinction of a cocaine-taking context that protects against drug-primed reinstatement is dependent on the metabotropic glutamate 5 receptor

Jee Hyun Kim, Christina Perry, Sophia Luikinga, Isabel Zbukvic, Robyn M Brown, Andrew J Lawrence

Journal article  |  2015  |  Addiction Biology

Role of alpha 4-and alpha 6-containing nicotinic receptors in the acquisition and maintenance of nicotine self-administration

Heather B Madsen, Harcharan S Koghar, Tine Pooters, Jim S Massalas, John Drago, Andrew J Lawrence

Journal article  |  2015  |  Addiction Biology

Relaxin-3 Receptor (RXFP3) Signalling Mediates Stress-Related Alcohol Preference in Mice

Andrew W Walker, Craig M Smith, Berenice E Chua, Elena V Krstew, Cary Zhang, Andrew L Gundlach, Andrew J Lawrence

Journal article  |  2015  |  PLOS ONE

Motor and behavioral phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cells

Luning Jiang, Claire O'Leary, Hyun Ah Kim, Clare L Parish, Jim Massalas, John L Waddington, Michelle E Ehrlich, Guenter Schuetz, Ilse Gantois, Andrew J Lawrence, John Drago

Journal article  |  2015  |  Neurobiology of Disease

Orexin/hypocretin role in reward: implications for opioid and other addictions

Corey Baimel, Selena E Bartlett, Lih-Chu Chiou, Andrew J Lawrence, John W Muschamp, Omkar Patkar, Li-Wei Tung, Stephanie L Borgland

Journal article  |  2015  |  British Journal of Pharmacology

DISTRIBUTION OF OREXIN-1 RECEPTOR-GREEN FLUORESCENT PROTEIN- (OX1-GFP) EXPRESSING NEURONS IN THE MOUSE BRAIN STEM AND PONS: CO-LOCALIZATION WITH TYROSINE HYDROXYLASE AND NEURONAL NITRIC OXIDE SYNTHASE

A Darwinkel, D Stanic, LC Booth, CN May, AJ Lawrence, ST Yao

Journal article  |  2014  |  NEUROSCIENCE

Found in translation? Commentary on a BJP themed issue about animal models in neuropsychiatry research

Andrew J Lawrence, John F Cryan

Journal article  |  2014  |  British Journal of Pharmacology

Role of cues and contexts on drug-seeking behaviour

Christina J Perry, Isabel Zbukvic, Jee Hyun Kim, Andrew J Lawrence

Journal article  |  2014  |  British Journal of Pharmacology

Chronic intermittent toluene inhalation initiated during adolescence in rats does not alter voluntary consumption of ethanol in adulthood

Alec LW Dick, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2014  |  ALCOHOL

Exploring the Modulation of Hypoxia-Inducible Factor (HIF)-1 alpha by Volatile Anesthetics as a Possible Mechanism Underlying Volatile Anesthetic-Induced CNS Injury

Emma K Giles, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2014  |  NEUROCHEMICAL RESEARCH

The effect of the mGlu5 negative allosteric modulator MTEP and NMDA receptor partial agonist D-cycloserine on Pavlovian conditioned fear

Charlotte E Handford, Shawn Tan, Andrew J Lawrence, Jee Hyun Kim

Journal article  |  2014  |  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Knockdown of CRF1 Receptors in the Ventral Tegmental Area Attenuates Cue- and Acute Food Deprivation Stress-Induced Cocaine Seeking in Mice

Nicola A Chen, Bianca Jupp, Yehezkel Sztainberg, Maya Lebow, Robyn M Brown, Jee Hyun Kim, Alon Chen, Andrew J Lawrence

Journal article  |  2014  |  JOURNAL OF NEUROSCIENCE

The partial agonist of the dopamine receptor 2, Aripiprazole, facilitates extinction in adolescent rats

DE Ganella, HB Madsen, IC Zbukvic, RW Coulthard, L Lee-Kardashyan, AJ Lawrence, JH Kim

Conference Proceedings  |  2014  |  JOURNAL OF NEUROCHEMISTRY

Drugs currently in Phase II clinical trials for cocaine addiction

Jee Hyun Kim, Andrew J Lawrence

Journal article  |  2014  |  Expert Opinion on Investigational Drugs

Characterization of a novel Neisseria gonorrhoeae penicillinase-producing plasmid isolated in Australia in 2012.

Ella Trembizki, Cameron Buckley, Andrew Lawrence, Monica Lahra, David Whiley, undefined GRAND Study Investigators

Journal article  |  2014  |  Antimicrobial Agents and Chemotherapy

Role of alpha4-and alpha6-containing nicotinic receptors in the acquisition & maintenance of nicotine self-administration

HB Madsen, HS Koghar, T Pooters, JS Massalas, J Drago, AJ Lawrence

Journal article  |  2014  |  Addiction Biology

mGlu5 & extinction of drug-seeking

AJ Lawrence

Conference Proceedings  |  2014  |  JOURNAL OF NEUROCHEMISTRY

Relaxin-3 mRNA levels in nucleus incertus correlate with alcohol and sucrose intake in rats

PJ Ryan, EV Krstew, M Sarwar, AL Gundlach, AJ Lawrence

Journal article  |  2014  |  DRUG AND ALCOHOL DEPENDENCE

Brucine suppresses ethanol intake and preference in alcohol-preferring Fawn-Hooded rats

Yu-ling Li, Qing Liu, Qi Gong, Jun-xu Li, Shou-peng Wei, Yan-ting Wang, Hui Liang, Min Zhang, Li Jing, Zheng Yong, Andrew J Lawrence, Jian-hui Liang

Journal article  |  2014  |  Acta Pharmacologica Sinica

Galanin-3 Receptor Antagonism by SNAP 37889 Reduces Motivation to Self-administer Alcohol and Attenuates Cue-Induced Reinstatement of Alcohol-Seeking in iP Rats

Belinda L Ash, Tim Quach, Spencer J Williams, Andrew J Lawrence, Elvan Djouma

Journal article  |  2014  |  Journal of Pharmacological Sciences

ENVIRONMENTAL MODIFICATION DURING ABSTINENCE PREVENTS MANIFESTATION OF DEPRESSIVE PHENOTYPE IN A MOUSE MODEL OF CHRONIC ALCOHOL CONSUMPTION

TY Pang, C Mo, X Du, W Catchlove, T Renoir, AJ Lawrence, AJ Hannan

Conference Proceedings  |  2014  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Escherichia coli Nissle 1917-derived factors reduce cell death and late apoptosis and increase transepithelial electrical resistance in a model of 5-fluorouracil-induced intestinal epithelial cell damage.

Hanru Wang, Susan EP Bastian, Ker Y Cheah, Andrew Lawrence, Gordon S Howarth

Journal article  |  2014  |  Cancer Biology & Therapy

We evaluated the capacity for supernatants (SNs) derived from Escherichia coli Nissle 1917 (EcN), cultured under different growth ..

The mGlu5 receptor regulates extinction of cocaine-driven behaviours

Michael K Bird, Peter Lohmann, Billy West, Robyn M Brown, Jeppe Kirchhoff, Clarke R Raymond, Andrew J Lawrence

Journal article  |  2014  |  DRUG AND ALCOHOL DEPENDENCE

Specific impairments in instrumental learning following chronic intermittent toluene inhalation in adolescent rats

Alec LW Dick, Martin Axelsson, Andrew J Lawrence, Jhodie R Duncan

Journal article  |  2014  |  PSYCHOPHARMACOLOGY

Chronic intermittent toluene inhalation in adolescent rats alters behavioural responses to amphetamine and MK801

Jhodie Rubina Duncan, Sarah Jane Gibbs, Andrew John Lawrence

Journal article  |  2014  |  EUROPEAN NEUROPSYCHOPHARMACOLOGY

Acamprosate Produces Its Anti-Relapse Effects Via Calcium

Rainer Spanagel, Valentina Vengeliene, Bernd Jandeleit, Wolf-Nicolas Fischer, Kent Grindstaff, Xuexiang Zhang, Mark A Gallop, Elena V Krstew, Andrew J Lawrence, Falk Kiefer

Journal article  |  2014  |  Neuropsychopharmacology

Chaperone heat shock protein 70 in nucleus accumbens core: a novel biological target of behavioural sensitization to morphine in rats

Yan-Ting Wang, Wang-Jun Qin, Qing Liu, Yu-Ling Li, Hui Liang, Feng Chen, Andrew J Lawrence, Xiang-Lin Zhang, Jian-Hui Liang

Journal article  |  2014  |  International Journal of Neuropsychopharmacology

Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells

Hyun Ah Kim, Luning Jiang, Heather Madsen, Clare L Parish, Jim Massalas, Arthur Smardencas, Claire O'Leary, Ilse Gantois, Colm O'Tuathaigh, John L Waddington, Michelle E Ehrlich, Andrew J Lawrence, John Drago

Journal article  |  2014  |  NEUROBIOLOGY OF DISEASE

An improved method to prepare an injectable microemulsion of the galanin-receptor 3 selective antagonist, SNAP 37889, using Kolliphor(®) HS 15.

Karlene J Scheller, Spencer J Williams, Andrew J Lawrence, Bevyn Jarrott, Elvan Djouma

Journal article  |  2014  |  MethodsX

Research into the galanin-3 (GAL3) receptor has many challenges, including the lack of commercially available selective ligands. W..

mGlu5 Receptors and Extinction of Drug-Seeking

Andrew J Lawrence

Journal article  |  2014  |  CURRENT NEUROPHARMACOLOGY

Relaxin-3 Regulates Stress-Induced Alcohol-Seeking in Rats

Andrew J Lawrence, Hanna Kastman, Phillip Ryan, Elena Krstew, Andrew L Gundlach

Conference Proceedings  |  2014  |  JOURNAL OF PHARMACOLOGICAL SCIENCES

Relaxin-3/RXFP3 system regulates alcohol-seeking

Philip J Ryan, Hanna E Kastman, Elena V Krstew, K Johan Rosengren, Mohammed Akhter Hossain, Leonid Churilov, John D Wade, Andrew L Gundlach, Andrew J Lawrence

Journal article  |  2013  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine

Jee Hyun Kim, Doron Lavan, Nicola Chen, Cecilia Flores, Helen Cooper, Andrew J Lawrence

Journal article  |  2013  |  PSYCHOPHARMACOLOGY

Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases

Arthur Smardencas, Kerelos Rizkalla, Hyun Ah Kim, Jim Massalas, Claire O'Leary, Michelle E Ehrlich, Guenter Schuetz, Andrew J Lawrence, John Drago

Journal article  |  2013  |  BMC NEUROSCIENCE

Central orexin (hypocretin) 2 receptor antagonism reduces ethanol self-administration, but not cue-conditioned ethanol-seeking, in ethanol-preferring rats

Robyn Mary Brown, Shaun Yon-Seng Khoo, Andrew John Lawrence

Journal article  |  2013  |  International Journal of Neuropsychopharmacology

Ascending otexinergic pathways and alcohol-seeking

Robyn Mary Brown, Andrew John Lawrence

Journal article  |  2013  |  Current Opinion in Neurobiology

Conventional Concepts and New Perspectives for Understanding the Addictive Properties of Inhalants

Jhodie Rubina Duncan, Andrew John Lawrence

Journal article  |  2013  |  JOURNAL OF PHARMACOLOGICAL SCIENCES

The Metabotropic Glutamate 5 Receptor Modulates Extinction and Reinstatement of Methamphetamine-Seeking in Mice

Rose Chesworth, Robyn M Brown, Jee Hyun Kim, Andrew J Lawrence

Journal article  |  2013  |  PLOS ONE

Depression-related behaviours displayed by female C57BL/6J mice during abstinence from chronic ethanol consumption are rescued by wheel-running

Terence Y Pang, Thibault Renoir, Xin Du, Andrew J Lawrence, Anthony J Hannan

Journal article  |  2013  |  European Journal of Neuroscience

Differences in galanin receptor binding in the nucleus accumbens may mediate alcohol consumption in alcohol-preferring rats

BL Ash, T Quach, SJ Williams, AJ Lawrence, E Djouma

Conference Proceedings  |  2013  |  JOURNAL OF NEUROCHEMISTRY

Central relaxin-3 receptor (RXFP3) activation decreases anxiety- and depressive-like behaviours in the rat

Philip J Ryan, Elena Buechler, Fazel Shabanpoor, Mohammed Akhter Hossain, John D Wade, Andrew J Lawrence, Andrew L Gundlach

Journal article  |  2013  |  BEHAVIOURAL BRAIN RESEARCH

The long-term consequences of inhalant abuse during adolescence; potential neuro-adaptations in reward pathways?

JR Duncan, A Dick, S Gibbs, AJ Lawrence

Conference Proceedings  |  2013  |  JOURNAL OF NEUROCHEMISTRY

Molecular chaperone heat shock protein 70 participates in the labile phase of the development of behavioural sensitization induced by a single morphine exposure in mice

Wang-Jun Qin, Yan-Ting Wang, Min Zhang, Rui-Ting Wen, Qing Liu, Yu-Ling Li, Feng Chen, Andrew J Lawrence, Jian-Hui Liang

Journal article  |  2013  |  International Journal of Neuropsychopharmacology

Behavioural and Anatomical Characterization of Mutant Mice With Targeted Deletion of D-1 Dopamine Receptor-Expressing Cells: Response to Acute Morphine

Daniela Babovic, Luning Jiang, Satoshi Goto, Ilse Gantois, Guenter Schuetz, Andrew J Lawrence, John L Waddington, John Drago

Journal article  |  2013  |  Journal of Pharmacological Sciences

Overview of Animal Models of Drug Addiction: Commonalities to Human Addiction

David H Overstreet, Robyn Brown, Andrew J Lawrence, Amir H Rezvani

Book Chapter  |  2013

Positive environmental modification of depressive phenotype and abnormal hypothalamic-pituitary-adrenal axis activity in female C57BL/6J mice during abstinence from chronic ethanol consumption

Terence Y Pang, Xin Du, William A Catchlove, Thibault Renoir, Andrew J Lawrenceand, Anthony J Hannan

Journal article  |  2013  |  Frontiers in Pharmacology

Maternally Administered Sustained-Release Naltrexone in Rats Affects Offspring Neurochemistry and Behaviour in Adulthood

Waleed O Farid, Andrew J Lawrence, Elena V Krstew, Robert J Tait, Gary K Hulse, Sarah A Dunlop

Journal article  |  2012  |  PLoS One

The Phosphodiesterase-4 (PDE4) Inhibitor Rolipram Decreases Ethanol Seeking and Consumption in Alcohol-Preferring Fawn-Hooded Rats

Rui-Ting Wen, Min Zhang, Wang-Jun Qin, Qing Liu, Wei-Ping Wang, Andrew J Lawrence, Han-Ting Zhang, Jian-Hui Liang

Journal article  |  2012  |  Alcoholism - Clinical and Experimental Research

The role of orexins/hypocretins in alcohol use and abuse: an appetitive-reward relationship

Andrezza K Kim, Robyn M Brown, Andrew J Lawrence

Journal article  |  2012  |  Frontiers in Behavioral Neuroscience

RECENT DEVELOPMENTS IN ADDICTION NEUROSCIENCE AND THEIR RELEVANCE TO CLINICAL PRACTICE

Dan Lubman, Murat Yucel, Andrew Lawrence, Rob Hester, Antonio Verdejo Garcia

Conference Proceedings  |  2012  |  DRUG AND ALCOHOL REVIEW

The role of metabotropic glutamate 5 receptor in addiction

JH Kim, AJ Lawrence

Book Chapter  |  2012

Adolescent Toluene Inhalation in Rats Affects White Matter Maturation with the Potential for Recovery Following Abstinence

Jhodie Rubina Duncan, Alec Lindsay Ward Dick, Gary Egan, Scott Kolbe, Maria Gavrilescu, David Wright, Dan Ian Lubman, Andrew John Lawrence

Journal article  |  2012  |  PLOS ONE

mGlu5 and adenosine A(2A) receptor interactions regulate the conditioned effects of cocaine

Robyn M Brown, Jhodie R Duncan, Monique R Stagnitti, Catherine Ledent, Andrew J Lawrence

Journal article  |  2012  |  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Novel medication targets for the treatment of alcoholism: preclinical studies.

Amir H Rezvani, Andrew J Lawrence, Maria P Arolfo, Edward D Levin, David H Overstreet

Journal article  |  2012  |  Recent Patents on CNS Drug Discovery

Alcoholism is a complex heterogeneous disease and a number of neurotransmitter and neuromodulator systems have been implicated in ..

THE PHOSPHODIESTERASE-4 (PDE4) INHIBITOR ROLIPRAM DECREASES ETHANOL SEEKING AND CONSUMPTION IN ALCOHOL-PREFERRING FAWN-HOODED RATS

RT Wen, M Zhang, WJ Qin, Q Liu, WP Wang, AJ Lawrence, HT Zhang, JH Liang

Conference Proceedings  |  2012  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The mGlu5 receptor antagonist MTEP attenuates opiate self-administration and cue-induced opiate-seeking behaviour in mice

Robyn M Brown, Monique R Stagnitti, Jhodie R Duncan, Andrew J Lawrence

Journal article  |  2012  |  Drug and Alcohol Dependence

The septal nuclei are selectively involved in the development of behavioural sensitization induced by a single morphine injection in rats

Q Liu, M Zhang, W-J Qin, Y-T Wang, Y-L Li, L Jing, J-X Li, AJ Lawrence, J-H Liang

Conference Proceedings  |  2012  |  BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Septal nuclei critically mediate the development of behavioral sensitization to a single morphine injection in rats

Qing Liu, Min Zhang, Wang-Jun Qin, Yan-Ting Wang, Yu-Ling Li, Li Jing, Jun-Xu Li, Andrew J Lawrence, Jian-Hui Liang

Journal article  |  2012  |  Brain Research

Investigation of the neuroanatomical substrates of reward seeking following protracted abstinence in mice

Heather B Madsen, Robyn M Brown, Jennifer L Short, Andrew J Lawrence

Journal article  |  2012  |  JOURNAL OF PHYSIOLOGY-LONDON

COMPULSIVE USE OF DOPAMINE REPLACEMENT THERAPY IN PARKINSON'S DISEASE: INSIGHTS INTO THE NEUROBIOLOGY OF ADDICTION

Robyn M Brown, Andrew J Lawrence

Journal article  |  2012  |  Addiction

The role of metabotropic glutamate receptors in addiction: Evidence from preclinical models

Jhodie R Duncan, Andrew J Lawrence

Journal article  |  2012  |  Pharmacology, Biochemistry and Behavior

Relaxin-3 null mutation mice display a circadian hypoactivity phenotype

CM Smith, IT Hosken, SW Sutton, AJ Lawrence, AL Gundlach

Journal article  |  2012  |  Genes, Brain and Behavior

CREB1 and CREB-binding protein in striatal medium spiny neurons regulate behavioural responses to psychostimulants

Heather B Madsen, Srigala Navaratnarajah, Jessica Farrugia, Elvan Djouma, Michelle Ehrlich, Theo Mantamadiotis, Jan Van Deursen, Andrew J Lawrence

Journal article  |  2012  |  Psychopharmacology

Molecular Neuroscience and Genetics

Jhodie R Duncan, Andrew J Lawrence

Book Chapter  |  2012

mGlu5 receptor functional interactions and addiction

Robyn M Brown, Sanam Mustafa, Mohammed Akli Ayoub, Peter R Dodd, Kevin DG Pfleger, Andrew J Lawrence

Journal article  |  2012  |  FRONTIERS IN PHARMACOLOGY

Comparative mutant mouse studies on the D1 receptor-mediated regulation of orofacial movement: forebrain vs striatum

Katsunori Tomiyama, Hyun Ah Kim, Anthony Kinsella, Michelle E Ehrlich, Guenter Schuetz, Noriaki Koshikawa, Andrew J Lawrence, John L Waddington, John Drago

Conference Proceedings  |  2012  |  JOURNAL OF PHARMACOLOGICAL SCIENCES

Neuroplasticity in addiction: cellular and transcriptional perspectives

Heather B Madsen, Robyn M Brown, Andrew J Lawrence

Journal article  |  2012  |  Frontiers in Molecular Neuroscience

Phenotypic Disruption to Orofacial Movement Topography in Conditional Mutants With Generalized CamKIIa/Cre D1Tox Versus Striatal-Specific DARPP-32/Cre D1Tox Ablation of D1 Dopamine Receptor-Expressing Cells

Katsunori Tomiyama, Hyun Ah Kim, Anthony Kinsella, Michelle E Ehrlich, Guenter Schuetz, Noriaki Koshikawa, Andrew J Lawrence, John L Waddington, John Drago

Journal article  |  2011  |  Synapse

mGLU5 AND ADENOSINE A(2A) RECEPTOR INTERACTIONS REGULATE THE CONDITIONED REINFORCING EFFECTS OF COCAINE

RM Brown, JR Duncan, MR Stagnitti, C Ledent, AJ Lawrence

Conference Proceedings  |  2011  |  JOURNAL OF NEUROCHEMISTRY

THE EFFECT OF ADOLESCENT TOLUENE EXPOSURE ON BEHAVIOURAL RESPONSES TO COCAINE IN ADULTHOOD: IMPACT OF DOSE AND EXPOSURE FREQUENCY

JR Duncan, A Lory, AJ Lawrence

Conference Proceedings  |  2011  |  JOURNAL OF NEUROCHEMISTRY

Audiogenic seizure proneness requires the contribution of two susceptibility loci in mice

M Catharine Jawahar, Carolina I Sari, Yvette M Wilson, Andrew J Lawrence, Thomas Brodnicki, Mark Murphy

Journal article  |  2011  |  Neurogenetics

CREB1 AND CREB BINDING PROTEIN IN STRIATAL MEDIUM SPINY NEURONS REGULATE BEHAVIOURAL RESPONSES TO PSYCHOSTIMULANTS

HB Madsen, S Navaratnarajah, J Farrugia, E Djouma, M Ehrlich, T Mantamadiotis, J Van Deursen, AJ Lawrence

Conference Proceedings  |  2011  |  JOURNAL OF NEUROCHEMISTRY

Beer promotes high levels of alcohol intake in adolescent and adult alcohol-preferring rats

Garth A Hargreaves, Emyo YJ Wang, Andrew J Lawrence, Iain S McGregor

Journal article  |  2011  |  Alcohol

Imaging - the interface with pharmacology: looking to the future

Andrew J Lawrence, Andreas Heinz

Journal article  |  2011  |  British Journal of Pharmacology

Relation of addiction genes to hypothalamic gene changes subserving genesis and gratification of a classic instinct, sodium appetite

Wolfgang B Liedtke, Michael J McKinley, Lesley L Walker, Hao Zhang, Andreas R Pfenning, John Drago, Sarah J Hochendoner, Donald L Hilton, Andrew J Lawrence, Derek A Denton

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation

Maithili Sashindranath, Andre Laval Samson, Catherine Eliza Downes, Peter John Crack, Andrew John Lawrence, Qiao-Xin Li, Ashley Quan Ping Ng, Nigel Charles Jones, Jessica Jade Farrugia, Eman Abdella, Jean-Dominique Vassalli, Rime Madani, Robert Lindsay Medcalf

Journal article  |  2011  |  Laboratory Investigation

The Necessity of alpha 4* Nicotinic Receptors in Nicotine-Driven Behaviors: Dissociation Between Reinforcing and Motor Effects of Nicotine

Elizabeth Cahir, Katie Pillidge, John Drago, Andrew J Lawrence

Journal article  |  2011  |  Neuropsychopharmacology

The orexin(1) receptor antagonist SB-334867 dissociates the motivational properties of alcohol and sucrose in rats

Bianca Jupp, Bedrija Krivdic, Elena Krstew, Andrew J Lawrence

Journal article  |  2011  |  Brain Research

Effect of the histone deacetylase inhibitors on behavioural sensitization to a single morphine exposure in mice

Li Jing, Juan Luo, Min Zhang, Wang-Jun Qin, Yu-Ling Li, Qing Liu, Yan-Ting Wang, Andrew J Lawrence, Jian-Hui Liang

Journal article  |  2011  |  Neuroscience Letters

Congenic Mouse Strains Enable Discrimination of Genetic Determinants Contributing to Fear and Fear Memory

Yvette M Wilson, Thomas C Brodnicki, Andrew J Lawrence, Mark Murphy

Journal article  |  2011  |  Behavior Genetics

Transcription and protein synthesis inhibitors reduce the induction of behavioural sensitization to a single morphine exposure and regulate Hsp70 expression in the mouse nucleus accumbens

Juan Luo, Li Jing, Wang-Jun Qin, Min Zhang, Andrew J Lawrence, Feng Chen, Jian-Hui Liang

Journal article  |  2011  |  International Journal of Neuropsychopharmacology

Discrete cue-conditioned alcohol-seeking after protracted abstinence: pattern of neural activation and involvement of orexin(1) receptors

B Jupp, E Krstew, G Dezsi, AJ Lawrence

Journal article  |  2011  |  British Journal of Pharmacology

The galanin-3 receptor antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring rats

Belinda L Ash, Shannon D Zanatta, Spencer J Williams, Andrew J Lawrence, Elvan Djouma

Journal article  |  2011  |  REGULATORY PEPTIDES

The galanin-3 receptor (GALR3) antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring (iP) rats

Elvan Djouma, Belinda L Ash, Andrew J Lawrence, Shannon D Zanatta, Spencer J Williams

Conference Proceedings  |  2011  |  JOURNAL OF PHARMACOLOGICAL SCIENCES

Traditional Chinese Medicine for Treatment of Alcoholism: from Ancient to Modern

Qing Liu, Andrew J Lawrence, Jian-Hui Liang

Journal article  |  2011  |  The American Journal of Chinese Medicine

Identification of Brain Nuclei Implicated in Cocaine-Primed Reinstatement of Conditioned Place Preference: A Behaviour Dissociable from Sensitization

Robyn Mary Brown, Jennifer Lynn Short, Andrew John Lawrence

Journal article  |  2010  |  PLoS ONE

MGLU5 RECEPTOR INTERACTIONS WITH OTHER GPCRS: RELEVANCE TO ALCOHOL-SEEKING

AJ Lawrence, M Stagnitti, RM Brown, MK Bird, C Adams, B West

Conference Proceedings  |  2010  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Deletion of CREB1 from the Dorsal Telencephalon Reduces Motivational Properties of Cocaine

Cameron S McPherson, Theo Mantamadiotis, Seong-Seng Tan, Andrew J Lawrence

Journal article  |  2010  |  Cerebral Cortex

Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice

Michael K Bird, Christopher A Reid, Feng Chen, Heneu O Tan, Steven Petrou, Andrew J Lawrence

Journal article  |  2010  |  International Journal of Neuropsychopharmacology

Regulation of alcohol-seeking by orexin (hypocretin) neurons

Andrew J Lawrence

Journal article  |  2010  |  Brain Research

Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptors

CL Adams, JL Short, AJ Lawrence

Journal article  |  2010  |  British Journal of Pharmacology

Age-related behavioural phenotype and cellular characterisation of mice with progressive ablation of D1 dopamine receptor-expressing cells

Daniela Babovic, Luning Jiang, Ilse Gantois, Andrew J Lawrence, Vincenzo Ferreri, Guenter Schuetz, John L Waddington, John Drago

Journal article  |  2010  |  Behavioural Brain Research

Systemic Administration of Arecoline Reduces Ethanol-Induced Sleeping Through Activation of Central Muscarinic Receptor in Mice

Yan-Ping Sun, Qing Liu, Juan Luo, Ping Guo, Feng Chen, Andrew J Lawrence, Jian-Hui Liang

Journal article  |  2010  |  Alcoholism - Clinical and Experimental Research

New horizons for therapeutics in drug and alcohol abuse

Bianca Jupp, Andrew J Lawrence

Journal article  |  2010  |  Pharmacology and Therapeutics

Effect of agmatine on alcohol-drinking behavior in alcohol-preferring FH/Wjd rats

L Jing, Y Qiu, M Zhang, WP Wang, F Chen, AJ Lawrence, J Li, JH Liang

Journal article  |  2009  |  Chinese Journal of New Drugs

The promiscuous mGlu5 receptor - a range of partners for therapeutic possibilities?

Michael K Bird, Andrew J Lawrence

Journal article  |  2009  |  Trends in Pharmacological Sciences

Factors regulating stress-induced alcohol-seeking and pharmacotherapeutic treatments: Brief introduction and rationale

Andrew J Lawrence

Journal article  |  2009  |  Alcohol

Suppression of Heavy Drinking and Alcohol Seeking by a Selective ALDH-2 Inhibitor

Maria P Arolfo, David H Overstreet, Lina Yao, Peidong Fan, Andrew J Lawrence, Guoxin Tao, Wing-Ming Keung, Bert L Vallee, M Foster Olive, Justin T Gass, Emanuel Rubin, Helen Anni, Clyde W Hodge, Joyce Besheer, Jeff Zablocki, Kwan Leung, Brent K Blackburn, Louis G Lange, Ivan Diamond

Journal article  |  2009  |  Alcoholism - Clinical and Experimental Research

Neurochemistry Underlying Relapse to Opiate Seeking Behaviour

Robyn M Brown, Andrew J Lawrence

Journal article  |  2009  |  Neurochemical Research

SELECTIVE ABLATION OF D1 RECEPTOR-EXPRESSING NEURONS IN THE STRIATUM IS ASSOCIATED WITH PARKINSONISM BUT NOT DYSTONIA

HA Kim, L Jiang, C O'Tuathaigh, JL Waddington, ME Ehrlich, AJ Lawrence, J Drago

Conference Proceedings  |  2009  |  JOURNAL OF NEUROCHEMISTRY

The galanin-3 antagonist, SNAP37889, reduces preference for operant-responding for ethanol in alcohol-preferring iP rats

E Djouma, AJ Lawrence, SD Zanatta, SJ Williams

Conference Proceedings  |  2009  |  European Neuropsychopharmacology

PRECLINICAL ASSESSMENT OF INTERVENTIONS TO PREVENT RELAPSE TO ALCOHOL-SEEKING

AJ Lawrence, MK Bird, C Adams, B Krivdic

Conference Proceedings  |  2009  |  JOURNAL OF NEUROCHEMISTRY

A Differential Role for the Adenosine A(2A) Receptor in Opiate Reinforcement vs Opiate-Seeking Behavior

Robyn Mary Brown, Jennifer Lynn Short, Michael Scott Cowen, Catherine Ledent, Andrew John Lawrence

Journal article  |  2009  |  Neuropsychopharmacology

Characteristics of alcohol-preferring behavior in FH/Wjd rats

L Jing, ZH Zhang, WP Wang, M Zhang, J Luo, F Chen, AJ Lawrence, JH Liang

Journal article  |  2009  |  Chinese Journal of Pharmacology and Toxicology

Behavioral Phenotyping of Mixed Background (129S5:B6) Relaxin-3 Knockout Mice

Craig M Smith, Andrew J Lawrence, Steve W Sutton, Andrew L Gundlach

Conference Proceedings  |  2009  |  Annals of the New York Academy of Science

APPROACHES TO THE STUDY OF THE GENETICS OF BEHAVIOURAL VARIATION USING MICE AND RATS

MC Jawahar, YM Wilson, AJ Lawrence, TC Brodnicki, M Murphy

Book Chapter  |  2009

Relaxin Family Peptides and Receptors in Mammalian Brain Anatomical Insights and Diverse Functional Possibilities

Andrew L Gundlach, Sherie Ma, Qian Sang, Pei-Juan Shen, Loretta Piccenna, Katayoun Sedaghat, Craig M Smith, Ross AD Bathgate, Andrew J Lawrence, Geoffrey W Tregear, John D Wade, David I Finkelstein, Pascal Bonaventure, Changlu Liu, Timothy W Lovenberg, Steve W Sutton

Journal article  |  2009  |  Annals of The New York Academy of Sciences

Group I metabotropic glutamate receptors: involvement in drug-seeking and drug-induced plasticity.

MK Bird, AJ Lawrence

Journal article  |  2009  |  Current Molecular Pharmacology

L-glutamate is the principal excitatory neurotransmitter at fast synapses in the mammalian central nervous system, and signals tho..

Type I mGLU receptors, drug-seeking & plasticity

AJ Lawrence, MS Cowen, CC Adams, MK Bird

Conference Proceedings  |  2008  |  NEUROPHARMACOLOGY

Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice

Michael K Bird, Jeppe Kirchhoff, Elvan Djouma, Andrew J Lawrence

Journal article  |  2008  |  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Differential between spatial learning and Pavlovian conditioning in mGlu5 deficient C57BL46J mice

MK Bird, AJ Lawrence

Conference Proceedings  |  2008  |  NEUROPHARMACOLOGY

Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways

Malcolm K Horne, Joohyung Lee, Feng Chen, Katherine Lanning, Doris Tomas, Andrew J Lawrence

Journal article  |  2008  |  Journal of Neurochemistry

Mglurs: Targets for alcohol therapeutics?

AJ Lawrence

Conference Proceedings  |  2008  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinaesia

Joohyung Lee, Wen-Mei Zhu, Davor Stanic, David I Finkelstein, Marjorie H Horne, Jasmine Henderson, Andrew J Lawrence, Louise O'Connor, Doris Tomas, John Drago, Malcolm K Horne

Journal article  |  2008  |  Brain

A novel, reversible and highly selective inhibitor of ALDH2, exhibits anxiolytic, anti-drinking and anti-addictive properties

Ivan Diamond, MP Arolfo, David H Overstreet, Andrew J Lawrence

Conference Proceedings  |  2008  |  ALCOHOL

Neuropharmacology of addiction - setting the scene

AJ Lawrence, PM Beart, PW Kalivas

Journal article  |  2008  |  British Journal of Pharmacology

Persistent downregulation of hippocampal CREB mRNA parallels a Y-maze deficit in adolescent rats following semi-chronic amphetamine administration

T Featherby, M van den Buuse, DI Lubman, AJ Lawrence

Journal article  |  2008  |  British Journal of Pharmacology

Inhalant abuse among adolescents: neurobiological considerations

DI Lubman, M Yucel, AJ Lawrence

Journal article  |  2008  |  British Journal of Pharmacology

Combined antagonism of glutamate mGlu5 and adenosine A(2A) receptors interact to regulate alcohol-seeking in rats

Cameron L Adams, Michael S Cowen, Jennifer L Short, Andrew J Lawrence

Journal article  |  2008  |  International Journal of Neuropsychopharmacology

Does angiotensin interact with dopaminergic mechanisms in the brain to modulate prepulse inhibition in mice?

Sally Martin, M Andrea Markus, Brian J Morris, Robin L Davisson, Andrew J Lawrence, Maarten van den Buuse

Journal article  |  2008  |  Neuropharmacology

Inhalant abuse among adolescents: neurobiological considerations

DI Lubman, M Yucel, AJ Lawrence

Journal article  |  2008  |  British Journal of Pharmacology

Quantification of phosphorylated cAMP-response element-binding protein expression throughout the brain of amphetamine-sensitized rats: activation of hypothalamic orexin a-containing neurons

Cameron S McPherson, Travis Featherby, Elena Krstew, Andrew J Lawrence

Journal article  |  2007  |  Journal of Pharmacology and Experimental Therapeutics

Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation

Yaroslav Teper, Douglas Whyte, Elizabeth Cahir, Henry A Lester, Sharon R Grady, Michael J Marks, Bruce N Cohen, Carlos Fonck, Tristan McClure-Begley, J Michael McIntosh, Cesar Labarca, Andrew Lawrence, Feng Chen, Ilse Gantois, Philip J Davies, Steven Petrou, Mark Murphy, John Waddington, Malcolm K Horne, Samuel F Berkovic, et al.

Journal article  |  2007  |  Neuroscience

The nuclear transcription factor CREB: Involvement in addiction, deletion models and looking forward

Cameron S McPherson, Andrew J Lawrence

Journal article  |  2007  |  Current Neuropharmacology

CGP7930: A positive allosteric modulator of the GABA(B) receptor

CL Adams, AJ Lawrence

Journal article  |  2007  |  CNS Drug Reviews

Central overexpression of angiotensin AT(1A) receptors prevents dopamine D-2 receptor regulation of alcohol consumption in mice

Rosanna Moore, Elena V Krstew, Jeppe Kirchhoff, Robin L Davisson, Andrew J Lawrence

Journal article  |  2007  |  Alcoholism - Clinical and Experimental Research

Optimisation of anti-psychotic therapeutics: a balancing act?

AJ Lawrence

Journal article  |  2007  |  British Journal of Pharmacology

Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior

Ilse Gantois, Ke Fang, Luning Jiang, Daniela Babovic, Andrew J Lawrence, Vincenzo Ferreri, Yaroslav Teper, Bianca Jupp, Jenna Ziebell, Cristina M Morganti-Kossmann, Terence J O'Brien, Rachel Nally, Guenter Schuetz, John Waddington, Gary F Egan, John Drago

Journal article  |  2007  |  Proceedings of the National Academy of Sciences of the United States of America

Changes in the serotonergic system in the main olfactory bulb of rats unilaterally deprived from birth to adulthood

C Gomez, JG Brinon, L Orio, MI Colado, AJ Lawrence, FC Zhou, M Vidal, MV Barbado, JR Alonso

Journal article  |  2007  |  Journal of Neurochemistry

Therapeutics for alcoholism: what's the future?

Andrew J Lawrence

Journal article  |  2007  |  Drug and Alcohol Review

Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control

David H Overstreet, Amir H Rezvani, Elvan Djouma, Abbas Parsian, Andrew J Lawrence

Journal article  |  2007  |  Neuroscience and Biobehavioral Reviews

Assessing appetitive and consummatory phases of ethanol self-administration in C57BL/6J mice under operant conditions: regulation by mGlu5 receptor antagonism

Michael S Cowen, Elena Krstew, Andrew J Lawrence

Journal article  |  2007  |  Psychopharmacology

Dopamine transporter and D-2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity

Xu-Feng Huang, Katerina Zavitsanou, Xin Huang, Yinghua Yu, HongQin Wang, Feng Chen, Andrew J Lawrence, Chao Deng

Journal article  |  2006  |  Behavioural Brain Research

Glutamate and GABA: Avenues for therapeutics?

Andrew J Lawrence

Conference Proceedings  |  2006  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment

David H Overstreet, Amir H Rezvani, Michael Cowen, Chen Feng, Andrew J Lawrence

Journal article  |  2006  |  Addiction Biology

Interactions between adenosine 2A receptors and metabotropic glutamate type 5 receptors regulate alcohol self-administration in iP rats

Cameron L Adams, Michael S Cowen, Jennifer L Short, Andrew J Lawrence

Conference Proceedings  |  2006  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The GABAB receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alchol-preferring rats (vol 50, pg 632, 2006)

Jian-Hui Liang, Feng Chen, Elena Krstew, Micael S Cowen, Fiona Y Carroll, Duncan Crawford, Phillip M Beart, Andrew J Lawrence

Journal article  |  2006  |  Neuropharmacology

Different effects of arecoline on ethanol- and pentobarbital-induced central suppression in mice

Jian-Hui Liang, Yan-Ping Sun, Rong Han, Juan Luo, Feng Chen, Andrew John Lawrence

Conference Proceedings  |  2006  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Exposure to amphetamine in rats during periadolescence establishes behavioural and extrastriatal neural sensitization in adulthood

Cameron S McPherson, Andrew J Lawrence

Journal article  |  2006  |  International Journal of Neuropsychopharmacology

The orexin system regulates alcohol-seeking in rats

Andrew J Lawrence, Michael S Cowen, Hong-Ju Yang, Feng Chen, Brian Oldfield

Journal article  |  2006  |  British Journal of Pharmacology

Assessing the role of the mGlu5 receptor in drug-seeking behaviour

AJ Lawrence

Conference Proceedings  |  2006  |  JOURNAL OF NEUROCHEMISTRY

The CRF1 receptor antagonist, antalarmin, reverses isolation-induced up-regulation of dopamine D-2 receptors in the amygdala and nucleus accumbens of Fawn-Hooded rats

Elvan Djouma, Katie Card, Daniel J Lodge, Andrew J Lawrence

Journal article  |  2006  |  European Journal of Neuroscience

The GABAB receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats

Jian-Hui Liang, Feng Chen, Elena Krstew, Michael S Cowen, Fiona Y Carroll, Duncan Crawford, Philip M Beart, Andrew J Lawrence

Journal article  |  2006  |  Neuropharmacology

The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats

JH Liang, F Chen, E Krstew, MS Cowen, FY Carroll, D Crawford, PM Beart, AJ Lawrence

Journal article  |  2006  |  Neuropharmacology

Alcoholism and neuropeptides: an update.

MS Cowen, AJ Lawrence

Journal article  |  2006  |  CNS & Neurological Disorders

As with other addictions, human alcoholism is characterised as a chronically relapsing condition. Consequently, the "holy grail" f..

Comparison of ethanol preference and neurochemical measures of mesolimbic dopamine and adenosine systems across different strains of mice

JL Short, J Drago, AJ Lawrence

Journal article  |  2006  |  Alcoholism - Clinical and Experimental Research

P2X purinoceptor subtypes on paraventricular nucleus neurones projecting to the rostral ventrolateral medulla in the rat

JL Cham, NC Owens, JA Barden, AJ Lawrence, E Badoer

Journal article  |  2006  |  Experimental Physiology

Receptor crosstalk: Characterization of mice deficient in dopamine D-1 and adenosine A(2A) receptors

JL Short, C Ledent, J Drago, AJ Lawrence

Journal article  |  2006  |  Neuropsychopharmacology

Genetic interdependence of adenosine and dopamine receptors: Evidence from receptor knockout mice

JL Short, C Ledent, E Borrelli, J Drago, AJ Lawrence

Journal article  |  2006  |  Neuroscience

Central autonomic integration of psychological stressors: Focus on cardiovascular modulation

SJ McDougall, RE Widdop, AJ Lawrence

Journal article  |  2005  |  Autonomic Neuroscience: Basic and Clinical

Central autonomic integration of psychological stressors: Focus on cardiovascular modulation

Stuart J McDougall, Robert E Widdop, Andrew J Lawrence

Journal article  |  2005  |  Autonomic Neuroscience - Basic & Clinical

The metabotropic glutamate 5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems

MS Cowen, E Djouma, AJ Lawrence

Journal article  |  2005  |  Journal of Pharmacology and Experimental Therapeutics

Mice lacking the alpha 4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and possess impaired dopamine transporter function

CL Parish, J Nunan, DI Finkelstein, FN McNamara, JY Wong, JL Waddington, RM Brown, AJ Lawrence, MK Horne, J Drago

Journal article  |  2005  |  Molecular Pharmacology

The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system

MS Cowen, C Adams, T Kraehenbuehl, V Vengeliene, AJ Lawrence

Journal article  |  2005  |  Addiction Biology

Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats

AJ Lawrence, CL Parish, F Chen, DJ Lodge, EV Krstew, K Card, DI Finkelstein, MK Horne

Journal article  |  2005  |  Journal of Neurochemistry

Alcohol and reward: Behavioural and neurochemical approaches to study craving and addiction

AJ Lawrence

Conference Proceedings  |  2005  |  JOURNAL OF NEUROCHEMISTRY

Purinergic modulation of cardiovascular function in the rat locus coeruleus

ST Yao, AJ Lawrence

Journal article  |  2005  |  British Journal of Pharmacology

A comparative autoradiographic study of the density of [H-3]SR95531, [H-3]MK-801 and [H-3]cGMP binding in the locus coeruleus and central pontine grey of spontaneously hypertensive and Wistar-Kyoto rats

ST Yao, AJ Lawrence

Journal article  |  2005  |  Naunyn-Schmiedeberg's Archives of Pharmacology

Differential gene expression in WKY and SHR brain following acute and chronic air-puff stress

SJ McDougall, RE Widdop, AJ Lawrence

Journal article  |  2005  |  Molecular Brain Research

Minocycline treatment attenuates microglia activation and non-angiotensin II[I-125]CGP42112 binding in brainstem following nodose ganglionectomy

CL Roulston, AJ Lawrence, RE Widdop, B Jarrott

Journal article  |  2005  |  Neuroscience

Differential cardiovascular responses to stressors in hypertensive and normotensive rats

SJ McDougall, AJ Lawrence, RE Widdop

Journal article  |  2005  |  Experimental Physiology

Medial prefrontal cortical integration of psychological stress in rats

SJ McDougall, RE Widdop, AJ Lawrence

Journal article  |  2004  |  European Journal of Neuroscience

Central alpha 2B-adrenoceptor antagonist prevents salt-induced hypertension in mice with brain-selective overexpression of angiotensin II AT1a receptors

NL Kanagy, E Lazartigues, X Tian, AJ Lawrence, RL Davisson

Conference Proceedings  |  2004  |  HYPERTENSION

Prepulse inhibition in fawn-hooded rats: increased sensitivity to 5-HT1A receptor stimulation

S Martin, AJ Lawrence, M van den Buuse

Journal article  |  2004  |  European Neuropsychopharmacology

Renovascular hypertension in mice with brain-selective overexpression of AT(1a) receptors is buffered by increased nitric oxide production in the periphery

E Lazartigues, AJ Lawrence, FS Lamb, RL Davisson

Journal article  |  2004  |  Circulation Research