Andrew Lawrence

Addiction-like behaviour towards high-fat high-sugar food predicts relapse propensity in both obesity prone and obesity resistant C57BL/6 J mice.

Anna L Horton, Erin J Campbell, Timothy D Aumann, Katrina R O'Brien, Andrew J Lawrence, Robyn M Brown

Journal article  |  2023  |  Prog Neuropsychopharmacol Biol Psychiatry

Compulsive overeating of palatable food is thought to underlie some forms of obesity. Similarities are often observed in the behav..

Journal of Neurochemistry embraces Transparent Peer Review

Andrew J Lawrence, Marco AM Prado

Journal article  |  2023  |  JOURNAL OF NEUROCHEMISTRY

In this editorial we explain how the Journal of Neurochemistry will embrace Transparent Peer Review. Our goal is to enhance the ex..

Cocaine regulates sensory filtering in cortical pyramidal neurons

Sean C Murphy, Luca Godenzini, Robertas Guzulaitis, Andrew J Lawrence, Lucy M Palmer

Journal article  |  2023  |  CELL REPORTS

Exposure to cocaine leads to robust changes in the structure and function of neurons within the mesocorticolimbic pathway. However..

The Effects of Transcranial Focused Ultrasound Stimulation of Nucleus Accumbens on Neuronal Gene Expression and Brain Tissue in High Alcohol-Preferring Rats.

Erdem Deveci, Fahri Akbaş, Arif Şanlı Ergun, Ayse Kurtulmuş, Ali Barlas Koçak, Rabia Kevser Boyraz, Olgu Enis Tok, Mehmet Şerif Aydın, Özge Kılıç, Ayhan Bozkurt, Ömer Uysal, Mukaddes Eşrefoğlu, Abdurrahim Koçyiğit, Ahmet Öztürk, Andrew J Lawrence, Ismet Kırpınar

Journal article  |  2023  |  Mol Neurobiol

We investigated the effect of low-intensity focused ultrasound (LIFU) on gene expression related to alcohol dependence and histolo..

Organisation of enkephalin inputs and outputs of the central nucleus of the amygdala in mice.

Aida Viden, Sarah S Ch'ng, Leigh C Walker, Arnav Shesham, Sabine M Hamilton, Craig M Smith, Andrew J Lawrence

Journal article  |  2022  |  J Chem Neuroanat

The central nucleus of the amygdala (CeA) is a key hub integrating sensory inputs and modulating behavioural outputs. The CeA is a..

Can we enhance the clinical efficacy of cognitive and psychological approaches to treat substance use disorders through understanding their neurobiological mechanisms?

Xavier J Maddern, Leigh C Walker, Erin J Campbell, Shalini Arunogiri, Paul S Haber, Kirsten Morley, Victoria Manning, E Zayra Millan, Gavan P McNally, Dan I Lubman, Andrew J Lawrence

Journal article  |  2022  |  Neurosci Biobehav Rev

Despite decades of research in the field of addiction, relapse rates for substance use disorders remain high. Consequently, there ..

Default Mode Network Modulation by Psychedelics: A Systematic Review

James J Gattuso, Daniel Perkins, Simon Ruffell, Andrew J Lawrence, Daniel Hoyer, Laura H Jacobson, Christopher Timmermann, David Castle, Susan L Rossell, Luke A Downey, Broc A Pagni, Nicole L Galvao-Coelho, David Nutt, Jerome Sarris

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Psychedelics are a unique class of drug which commonly produce vivid hallucinations as well as profound psychological and mystical..

Clinical Effectiveness of Muscarinic Receptor-Targeted Interventions in Neuropsychiatric Disorders: A Systematic Review

Shivani Vaidya, Alexandre A Guerin, Leigh C Walker, Andrew J Lawrence

Journal article  |  2022  |  CNS DRUGS

BACKGROUND: For decades, treatment of mood disorders, psychoses, anxiety and dementia have been confounded by limited efficacy and..

Examining ventral subiculum and basolateral amygdala projections to the nucleus accumbens shell: Differential expression of VGLuT1, VGLuT2 and VGaT in the rat.

Shubo Jin, Xavier J Maddern, Erin J Campbell, Andrew J Lawrence

Journal article  |  2022  |  Neurosci Lett

Projections to the striatum are well-identified. For example, in the ventral striatum, two major inputs to the medial nucleus accu..

How the brain regulates alcohol intake

Leigh C Walker, Paulo Pinares-Garcia, Andrew J Lawrence

Journal article  |  2022  |  ELIFE

A neural pathway involved in goal-oriented behaviours becomes dysregulated during binge drinking and alcohol use disorder.