Neil Young

High-quality reference genome for Clonorchis sinensis.

Neil D Young, Andreas J Stroehlein, Liina Kinkar, Tao Wang, Woon-Mok Sohn, Bill CH Chang, Parwinder Kaur, David Weisz, Olga Dudchenko, Erez Lieberman Aiden, Pasi K Korhonen, Robin B Gasser

Journal article  |  2021  |  Genomics

The Chinese liver fluke, Clonorchis sinensis, causes the disease clonorchiasis, affecting ~35 million people in regions of China, ..

Bulinus truncatus transcriptome – a resource to enable molecular studies of snail and schistosome biology

Andreas J Stroehlein, Pasi K Korhonen, David Rollinson, J Russell Stothard, Ross S Hall, Robin B Gasser, Neil D Young

Journal article  |  2021  |  Current Research in Parasitology & Vector-Borne Diseases

Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): Implications for snail systematics and schistosome epidemiology

Neil D Young, Liina Kinkar, Andreas J Stroehlein, Pasi K Korhonen, J Russell Stothard, David Rollinson, Robin B Gasser

Journal article  |  2021  |  Current Research in Parasitology & Vector-Borne Diseases

Major SCP/TAPS protein expansion in Lucilia cuprina is associated with novel tandem array organisation and domain architecture

Yair DJ Prawer, Andreas J Stroehlein, Neil D Young, Shilpa Kapoor, Ross S Hall, Razi Ghazali, Phillip Batterham, Robin B Gasser, Trent Perry, Clare A Anstead

Journal article  |  2020  |  Parasites & Vectors

BACKGROUND: Larvae of the Australian sheep blowfly, Lucilia cuprina, parasitise sheep by feeding on skin excretions, dermal tissue..

Toward integrative 'omics of the barber's pole worm and related parasitic nematodes

Guangxu Ma, Robin B Gasser, Tao Wang, Pasi K Korhonen, Neil D Young

Journal article  |  2020  |  Infection Genetics and Evolution

Advances in nucleic acid sequencing, mass spectrometry and computational biology have facilitated the identification, annotation a..

High-quality nuclear genome for Sarcoptes scabiei-A critical resource for a neglected parasite

Pasi K Korhonen, Robin B Gasser, Guangxu Ma, Tao Wang, Andreas J Stroehlein, Neil D Young, Ching-Seng Ang, Deepani D Fernando, Hieng C Lu, Sara Taylor, Simone L Reynolds, Ehtesham Mofiz, Shivashankar H Najaraj, Harsha Gowda, Anil Madugundu, Santosh Renuse, Deborah Holt, Akhilesh Pandey, Anthony T Papenfuss, Katja Fischer

Journal article  |  2020  |  PLoS Neglected Tropical Diseases

The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin of humans and animals worldwide. I..

Molecular characterisation and vaccine efficacy of two novel developmentally regulated surface tegument proteins of Fasciola hepatica

Paul McCusker, Hayley Toet, Vignesh Rathinasamy, Neil Young, Travis Beddoe, Glenn Anderson, Robert Dempster, Paul McVeigh, Erin McCammick, Duncan Wells, Angela Mousley, Nikki J Marks, Aaron G Maule, Terry W Spithill

Journal article  |  2020  |  Veterinary Parasitology

The surface tegument of Fasciola hepatica is a crucial tissue due to its key role at the host-parasite interface. We characterised..

Combined use of feature engineering and machine-learning to predict essential genes in Drosophila melanogaster.

Tulio L Campos, Pasi K Korhonen, Andreas Hofmann, Robin B Gasser, Neil D Young

Journal article  |  2020  |  NAR Genom Bioinform

Characterizing genes that are critical for the survival of an organism (i.e. essential) is important to gain a deep understanding ..

Diversity in the intrinsic apoptosis pathway of nematodes

Neil D Young, Tiffany J Harris, Marco Evangelista, Sharon Tran, Merridee A Wouters, Tatiana P Soares da Costa, Nadia J Kershaw, Robin B Gasser, Brian J Smith, Erinna F Lee, W Douglas Fairlie

Journal article  |  2020  |  Communications Biology

Early studies of the free-living nematode C. elegans informed us how BCL-2-regulated apoptosis in humans is regulated. However, su..

First record of a tandem-repeat region within the mitochondrial genome ofClonorchis sinensisusing a long-read sequencing approach

Liina Kinkar, Neil D Young, Woon-Mok Sohn, Andreas J Stroehlein, Pasi K Korhonen, Robin B Gasser

Journal article  |  2020  |  PLoS Neglected Tropical Diseases

BACKGROUND: Mitochondrial genomes provide useful genetic markers for systematic and population genetic studies of parasitic helmin..