Neil Young

The developmental phosphoproteome of Haemonchus contortus.

Tao Wang, Guangxu Ma, Ching-Seng Ang, Pasi K Korhonen, Andreas J Stroehlein, Neil D Young, Andreas Hofmann, Bill CH Chang, Nicholas A Williamson, Robin B Gasser

Journal article  |  2020  |  Journal of Proteomics

Protein phosphorylation plays essential roles in many cellular processes. Despite recent progress in the genomics, transcriptomics..

High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing

Andreas J Stroehlein, Pasi K Korhonen, Teik Min Chong, Yan Lue Lim, Kok Gan Chan, Bonnie Webster, David Rollinson, Paul J Brindley, Robin B Gasser, Neil D Young

Journal article  |  2019  |  GigaScience

BACKGROUND: Schistosoma haematobium causes urogenital schistosomiasis, a neglected tropical disease affecting >100 million people ..

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

Tao Wang, Guangxu Ma, Ching-Seng Ang, Pasi K Korhonen, Anson Koehler, Neil D Young, Shuai Nie, Nicholas A Williamson, Robin B Gasser

Journal article  |  2019  |  Journal of Proteomics

Parasitic nematodes of humans, animals and plants have a major, adverse impact on global health and agricultural production worldw..

Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

Guangxu Ma, Tao Wang, Pasi K Korhonen, Neil D Young, Shuai Nie, Ching-Seng Ang, Nicholas A Williamson, Gavin E Reid, Robin B Gasser

Journal article  |  2019  |  PLOS Pathogens

Here, we discovered an endogenous dafachronic acid (DA) in the socioeconomically important parasitic nematode Haemonchus contortus..

Comparative genome analysis indicates high evolutionary potential of pathogenicity genes in Colletotrichum tanaceti

Ruvini Lelwala, Pasi K Korhonen, Neil D Young, Jason B Scott, Peter K Ades, Robin B Gasser, Paul WJ Taylor

Journal article  |  2019  |  PLOS ONE

Exploration of antibiotic resistance risks in a veterinary teaching hospital with Oxford Nanopore long read sequencing

Kanishka Indiwari Kamathewatta, Rhys Nathan Bushell, Neil David Young, Mark Anthony Stevenson, Helen Billman-Jacobe, Glenn Francis Browning, Marc Serge Marenda

Journal article  |  2019  |  PLOS ONE

A systematic study towards evolutionary and epidemiological dynamics of currently predominant H5 highly pathogenic avian influenza viruses in Vietnam

Thanh Nguyen Lam, Simon M Firestone, Mark A Stevenson, Neil D Young, Leslie D Sims, Huy Chu Duc, Ngoc Nguyen Tien, Van Nguyen Long, Thanh Le Tung, Van Nguyen Hung, Nam Nguyen Hung, Ngoc Tien Tien, Dang Nguyen Tho, Ngoc Tran Bich, Keita Matsuno, Masatoshi Okamatsu, Hiroshi Kida, Yoshihiro Sakoda

Journal article  |  2019  |  Scientific Reports

Long-read sequencing reveals a 4.4kb tandem repeat region in the mitogenome of Echinococcus granulosus (sensu stricto) genotype G1

Liina Kinkar, Pasi K Korhonen, Huimin Cai, Charles G Gauci, Marshall W Lightowlers, Urmas Saarma, David J Jenkins, Jiandong Li, Junhua Li, Neil D Young, Robin B Gasser

Journal article  |  2019  |  Parasites & Vectors

Dauer signalling pathway model for Haemonchus contortus

Guangxu Ma, Tao Wang, Pasi K Korhonen, Andreas J Stroehlein, Neil D Young, Robin B Gasser

Journal article  |  2019  |  Parasites & Vectors

Transcriptional alterations in Caenorhabditis elegans following exposure to an anthelmintic fraction of the plant Picria fel-terrae Lour.

Rasika Kumarasingha, Neil D Young, Tiong-Chia Yeo, Diana SL Lim, Chu-Lee Tu, Enzo A Palombo, Jillian M Shaw, Robin B Gasser, Peter R Boag

Journal article  |  2019  |  Parasites & Vectors

Common workflow language (CWL)-based software pipeline for de novo genome assembly from long- and short-read data

Pasi K Korhonen, Ross S Hall, Neil D Young, Robin B Gasser

Journal article  |  2019  |  GigaScience

Molecular evidence for distinct modes of nutrient acquisition between visceral and neurotropic schistosomes of birds

Roman Leontovyc, Neil D Young, Pasi K Korhonen, Ross S Hall, Jana Bulantova, Veronika Jerabkova, Martin Kasny, Robin B Gasser, Petr Horak

Journal article  |  2019  |  Scientific Reports

Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity

Patpicha Arunsan, Wannaporn Ittiprasert, Michael J Smout, Christina J Cochran, Victoria H Mann, Sujittra Chaiyadet, Shannon E Karinshak, Banchob Sripa, Neil David Young, Javier Sotillo, Alex Loukas, Paul J Brindley, Thewarach Laha

Journal article  |  2019  |  eLife

Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host

Guangxu Ma, Tao Wang, Pasi K Korhonen, Shuai Nie, Gavin E Reid, Andreas J Stroehlein, Anson V Koehler, Bill CH Chang, Andreas Hofmann, Neil D Young, Robin B Gasser

Journal article  |  2019  |  Parasit Vectors

Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobium

Harald Oey, Martha Zakrzewski, Kerstin Gravermann, Neil D Young, Pasi K Korhonen, Geoffrey N Gobert, Sujeevi Nawaratna, Shihab Hasan, David M Martinez, Hong You, Martin Lavin, Malcolm K Jones, Mark A Ragan, Jens Stoye, Ana Oleaga, Aidan M Emery, Bonnie Webster, David Rollinson, Robin B Gasser, Donald P McManus, et al.

Journal article  |  2019  |  PLOS Pathogens

Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite-host cross talk

Eline P Hansen, Bastian Fromm, Sidsel D Andersen, Antonio Marcilla, Kasper L Andersen, Anne Borup, Andrew R Williams, Aaron R Jex, Robin B Gasser, Neil D Young, Ross S Hall, Allan Stensballe, Vladimir Ovchinnikov, Yan Yan, Merete Fredholm, Stig M Thamsborg, Peter Nejsum

Journal article  |  2019  |  Journal of Extracellular Vesicles

An Evaluation of Machine Learning Approaches for the Prediction of Essential Genes in Eukaryotes Using Protein Sequence-Derived Features

Tulio L Campos, Pasi K Korhonen, Robin B Gasser, Neil D Young

Journal article  |  2019  |  Computational and Structural Biotechnology Journal

The availability of whole-genome sequences and associated multi-omics data sets, combined with advances in gene knockout and knock..

Interactive online application for the prediction, ranking and prioritisation of drug targets in Schistosoma haematobium

Andreas J Stroehlein, Robin B Gasser, Ross S Hall, Neil D Young

Journal article  |  2018  |  Parasites & Vectors

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control

Guangxu Ma, Tao Wang, Pasi K Korhonen, Ching-Seng Ang, Nicholas A Williamson, Neil D Young, Andreas J Stroehlein, Ross S Hall, Anson V Koehler, Andreas Hofmann, Robin B Gasser

Journal article  |  2018  |  International Journal for Parasitology

Improved genomic resources and new bioinformatic workflow for the carcinogenic parasite Clonorchis sinensis: Biotechnological implications

Daxi Wang, Pasi K Korhonen, Robin B Gasser, Neil D Young

Journal article  |  2018  |  Biotechnology Advances

Advances in kinome research of parasitic worms - implications for fundamental research and applied biotechnological outcomes

Andreas J Stroehlein, Neil D Young, Robin B Gasser

Journal article  |  2018  |  Biotechnology Advances

Best practice data life cycle approaches for the life sciences

Philippa Griffin, Jyoti Khadake, Kate LeMay, Suzanna Lewis, Sandra Orchard, Andrew Pask, Bernard Pope, Ute Roessner, Keith Russell, Torsten Seemann, Andrew Treloar, Sonika Tyagi, Jeffrey Christiansen, Saravanan Dayalan, Simon Gladman, Sandra Hangartner, Helen Hayden, William WH Ho, Gabriel Keeble-Gagnère, Pasi Korhonen, et al.

Journal article  |  2018  |  F1000Research

Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested by advance..

A Novel Glaesserella sp Isolated from Pigs with Severe Respiratory Infections Has a Mosaic Genome with Virulence Factors Putatively Acquired by Horizontal Transfer

Anne E Watt, Glenn F Browning, Alistair R Legione, Rhys N Bushell, Andrew Stent, Ross S Cutler, Neil D Young, Marc S Marenda

Journal article  |  2018  |  Applied and Environmental Microbiology

Improved strategy for the curation and classification of kinases, with broad applicability to other eukaryotic protein groups

Andreas J Stroehlein, Neil D Young, Robin B Gasser

Journal article  |  2018  |  Scientific Reports

The small RNA complement of adult Schistosoma haematobium

Andreas J Stroehlein, Neil D Young, Pasi K Korhonen, Ross S Hall, Aaron R Jex, Bonnie L Webster, David Rollinson, Paul J Brindley, Robin B Gasser

Journal article  |  2018  |  PLOS Neglected Tropical Diseases

Innate immune genes in persistent mating-induced endometritis in horses

Christina D Marth, Simon M Firestone, Dave Hanlon, Lisa Y Glenton, Glenn F Browning, Neil D Young, Natali Krekeler

Journal article  |  2018  |  Reproduction, Fertility and Development

Clonorchis sinensis and Clonorchiasis: The Relevance of Exploring Genetic Variation

Daxi Wang, Neil D Young, Pasi K Korhonen, Robin B Gasser

Journal article  |  2018  |  Advances in parasitology

Opisthorchis viverrini Draft Genome - Biomedical Implications and Future Avenues

Neil D Young, Robin B Gasser

Journal article  |  2018  |  Advances in Parasitology

Whipworm kinomes reflect a unique biology and adaptation to the host animal

Andreas J Stroehlein, Neil D Young, Pasi K Korhonen, Bill CH Chang, Peter Nejsum, Edoardo Pozio, Giuseppe La Rosa, Paul W Sternberg, Robin B Gasser

Journal article  |  2017  |  International Journal for Parasitology

Use of a bioinformatic-assisted primer design strategy to establish a new nested PCR-based method for Cryptosporidium

Anson V Koehler, Pasi K Korhonen, Ross S Hall, Neil D Young, Tao Wang, Shane R Haydon, Robin B Gasser

Journal article  |  2017  |  Parasites & Vectors

yy Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain

Sarah Preston, Pasi K Korhonen, Laurent Mouchiroud, Matteo Cornaglia, Sean L McGee, Neil D Young, Rohan A Davis, Simon Crawford, Cameron Nowell, Brendan RE Ansell, Gillian M Fisher, Katherine T Andrews, Bill CH Chang, Martin AM Gijs, Paul W Sternberg, Johan Auwerx, Jonathan Baell, Andreas Hofmann, Abdul Jabbar, Robin B Gasser

Journal article  |  2017  |  The FASEB Journal

A novel ex vivo immunoproteomic approach characterising Fasciola hepatica tegumental antigens identified using immune antibody from resistant sheep

Timothy C Cameron, Ira Cooke, Pierre Faou, Hayley Toet, David Piedrafita, Neil Young, Vignesh Rathinasamy, Travis Beddoe, Glenn Anderson, Robert Dempster, Terry W Spithill

Journal article  |  2017  |  International Journal for Parasitology

Genomics of worms, with an emphasis on Opisthorchis viverrini - opportunities for fundamental discovery and biomedical outcomes

Robin B Gasser, Patrick Tan, Bin Tean Teh, Sopit Wongkham, Neil D Young

Journal article  |  2017  |  PARASITOLOGY INTERNATIONAL

Genomics of worms, with an emphasis on Opisthorchis viverrini - opportunities for fundamental discovery and biomedical outcomes.

Robin B Gasser, Patrick Tan, Bin Tean Teh, Sopit Wongkham, Neil D Young

Journal article  |  2017  |  Parasitology International

Neglected tropical diseases cause substantial morbidity and mortality in animals and people globally. Opisthorchiasis is one such ..

Best Practice Data Life Cycle Approaches for the Life Sciences

Philippa Griffin, Jyoti Khadake, Kate LeMay, Suzanna Lewis, Sandra Orchard, Andrew Pask, Bernard Pope, Ute Roessner, Keith Russell, Torsten Seemann, Andrew Treloar, Sonika Tyagi, Jeffrey Christiansen, Saravanan Dayalan, Simon Gladman, Sandra Hangartner, Helen Hayden, William Ho, Gabriel Keeble-Gagnère, Pasi Korhonen, et al.

Journal article  |  2017  |  F1000Research

Abstract Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested b..

Mitochondrial genomic comparison of Clonorchis sinensis from South Korea with other isolates of this species

Daxi Wang, Neil D Young, Anson V Koehler, Patrick Tan, Woon-Mok Sohn, Pasi K Korhonen, Robin B Gasser

Journal article  |  2017  |  Infection, Genetics and Evolution

Probing function and structure of trehalose-6phosphate phosphatases from pathogenic organisms suggests distigroupingsnct molecular

Megan Cross, Romain Lepage, Siji Rajan, Sonja Biberacher, Neil D Young, Bo-Na Kim, Mark J Coster, Robin B Gasser, Jeong-Sun Kim, Andreas Hofmann

Journal article  |  2017  |  The FASEB Journal

The apicoplast genomes of two taxonomic units of Babesia from sheep

Tao Wang, Guiquan Guan, Pasi K Korhonen, Anson V Koehler, Ross S Hall, Neil D Young, Hong Yin, Robin B Gasser

Journal article  |  2017  |  Veterinary Parasitology

Best practice data life cycle approaches for the life sciences.

Philippa C Griffin, Jyoti Khadake, Kate S LeMay, Suzanna E Lewis, Sandra Orchard, Andrew Pask, Bernard Pope, Ute Roessner, Keith Russell, Torsten Seemann, Andrew Treloar, Sonika Tyagi, Jeffrey H Christiansen, Saravanan Dayalan, Simon Gladman, Sandra B Hangartner, Helen L Hayden, William WH Ho, Gabriel Keeble-Gagnère, Pasi K Korhonen, et al.

Journal article  |  2017  |  F1000Research

Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested by advance..

The Battle Against Flystrike - Past Research and New Prospects Through Genomics

Clare A Anstead, Trent Perry, Stephen Richards, Pasi K Korhonen, Neil D Young, Vernon M Bowles, Philip Batterham, Robin B Gasser

Journal article  |  2017  |  Advances in Parasitology

Best practice data life cycle approaches for the life sciences.

Philippa C Griffin, Jyoti Khadake, Kate S LeMay, Suzanna E Lewis, Sandra Orchard, Andrew Pask, Bernard Pope, Ute Roessner, Keith Russell, Torsten Seemann, Andrew Treloar, Sonika Tyagi, Jeffrey H Christiansen, Saravanan Dayalan, Simon Gladman, Sandra B Hangartner, Helen L Hayden, William WH Ho, Gabriel Keeble-Gagnère, Pasi K Korhonen, et al.

Journal article  |  2017  |  F1000Research

Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested by advance..

Mitochondrial genomes of two Babesia taxa from sheep in China as a foundation for population genetic and epidemiological investigations

Tao Wang, Guiquan Guan, Pasi K Korhonen, Anson V Koehler, Neil D Young, Ross S Hall, Hong Yin, Robin B Gasser

Journal article  |  2017  |  Infection, Genetics and Evolution

Isolation of Tasmanian Rickettsia-like organism (RLO) from farmed salmonids: identification of multiple serotypes and confirmation of pathogenicity

RN Morrison, ND Young, G Knowles, MC Cornish, J Carson

Journal article  |  2016  |  Diseases of Aquatic Organisms

Oestrous cycle-dependent equine uterine immune response to induced infectious endometritis

CD Marth, SM Firestone, LY Glenton, GF Browning, ND Young, N Krekeler

Journal article  |  2016  |  Veterinary research

Oestrous cycle-dependent equine uterine immune response to induced infectious endometritis

Christina D Marth, Simon M Firestone, Lisa Y Glenton, Glenn F Browning, Neil D Young, Natali Krekeler

Journal article  |  2016  |  Veterinary Research

Genomic resources for a unique, low-virulence Babesia taxon from China

Guiquan Guan, Pasi K Korhonen, Neil D Young, Anson V Koehler, Tao Wang, Youquan Li, Zhijie Liu, Jianxun Luo, Hong Yin, Robin B Gasser

Journal article  |  2016  |  Parasites & Vectors

Genomic resources for a unique, low-virulence Babesia taxon from China

G Guan, PK Korhonen, ND Young, AV Koehler, T Wang, Y Li, Z Liu, J Luo, H Yin, RB Gasser

Journal article  |  2016  |  Parasites & vectors

Making sense of genomes of parasitic worms: Tackling bioinformatic challenges

Pasi K Korhonen, Neil D Young, Robin B Gasser

Journal article  |  2016  |  Biotechnology Advances

Analyses of Compact Trichinella Kinomes Reveal a MOS-Like Protein Kinase with a Unique N-Terminal Domain

Andreas J Stroehlein, Neil D Young, Pasi K Korhonen, Bill CH Chang, Paul W Sternberg, Giuseppe La Rosa, Edoardo Pozio, Robin B Gasser

Journal article  |  2016  |  G3: Genes|Genomes|Genetics

A blow to the fly - Lucilia cuprina draft genome and transcriptome to support advances in biology and biotechnology

Clare A Anstead, Philip Batterham, Pasi K Korhonen, Neil D Young, Ross S Hall, Vernon M Bowles, Stephen Richards, Maxwell J Scott, Robin B Gasser

Journal article  |  2016  |  Biotechnology Advances

CAP protein superfamily members in Toxocara canis

Andreas J Stroehlein, Neil D Young, Ross S Hall, Pasi K Korhonen, Andreas Hofmann, Paul W Sternberg, Abdul Jabbar, Robin B Gasser

Journal article  |  2016  |  Parasites & Vectors

MicroRNAs of Toxocara canis and their predicted functional roles

Guangxu Ma, Yongfang Luo, Honghong Zhu, Yongli Luo, Pasi K Korhonen, Neil D Young, Robin B Gasser, Rongqiong Zhou

Journal article  |  2016  |  Parasites & Vectors

Pipeline for the identification and classification of ion channels in parasitic flatworms

Bahiyah Nor, Neil D Young, Pasi K Korhonen, Ross S Hall, Patrick Tan, Andrew Lonie, Robin B Gasser

Journal article  |  2016  |  Parasites & Vectors

The complement of family M1 aminopeptidases of Haemonchus contortus - Biotechnological implications

Namitha Mohandas, Neil D Young, Abdul Jabbar, Pasi K Korhonen, Anson V Koehler, Ross S Hall, Min Hu, Andreas Hofmann, Robin B Gasser

Journal article  |  2016  |  Biotechnology Advances

Reconstruction of the insulin-like signalling pathway of Haemonchus contortus

Namitha Mohandas, Min Hu, Andreas J Stroehlein, Neil D Young, Paul W Sternberg, James B Lok, Robin B Gasser

Journal article  |  2016  |  Parasites & Vectors

Phylogenomic and biogeographic reconstruction of the Trichinella complex

Pasi K Korhonen, Edoardo Pozio, Giuseppe La Rosa, Bill CH Chang, Anson V Koehler, Eric P Hoberg, Peter R Boag, Patrick Tan, Aaron R Jex, Andreas Hofmann, Paul W Sternberg, Neil D Young, Robin B Gasser

Journal article  |  2016  |  Nature Communications

Whole transcriptome profiling of adult and infective stages of the trematode Opisthorchis felineus

Mikhail Yu Pomaznoy, Maria D Logacheva, Neil D Young, Aleksey A Penin, Nikita I Ershov, Alexey V Katokhin, Viatcheslav A Mordvinov

Journal article  |  2016  |  Parasitology International

Comparative Transcriptomic Exploration Reveals Unique Molecular Adaptations of Neuropathogenic Trichobilharzia to Invade and Parasitize Its Avian Definitive Host

Roman Leontovyc, Neil D Young, Pasi K Korhonen, Ross S Hall, Patrick Tan, Libor Mikes, Martin Kasny, Petr Horak, Robin B Gasser

Journal article  |  2016  |  PLOS Neglected Tropical Diseases

Understanding Haemonchus contortus Better Through Genomics and Transcriptomics

RB Gasser, EM Schwarz, PK Korhonen, ND Young

Book Chapter  |  2016  |  Advances in Parasitology

Exploring the molecular mechanisms of parasite-host interactions with a view towards new therapeutics and vaccines.

Megan Cross, Emma Klepzig, Madeleine Dallaston, Neil D Young, Ulla-Maja Bailey, Lyndel Mason, Malcolm K Jones, Robin B Gasser, Andreas Hofmann

Journal article  |  2016  |  Postepy biochemii

Despite the massive disease burden worldwide caused by parasitic nematodes and other infectious pathogens, the molecular basis of ..

Effect of ovarian hormones on the healthy equine uterus: a global gene expression analysis

Christina D Marth, Neil D Young, Lisa Y Glenton, Drew M Noden, Glenn F Browning, Natali Krekeler

Journal article  |  2016  |  Reproduction, Fertility and Development

Harnessing the Toxocara Genome to Underpin Toxocariasis Research and New Interventions

Robin B Gasser, Pasi K Korhonen, Xing-Quan Zhux, Neil D Young

Book Chapter  |  2016  |  Advances in Parasitology

The Haemonchus contortus kinome - a resource for fundamental molecular investigations and drug discovery

Andreas J Stroehlein, Neil D Young, Pasi K Korhonen, Abdul Jabbar, Andreas Hofmann, Paul W Sternberg, Robin B Gasser

Journal article  |  2015  |  Parasites & Vectors

Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets

Andreas J Stroehlein, Neil D Young, Aaron R Jex, Paul W Sternberg, Patrick Tan, Peter R Boag, Andreas Hofmann, Robin B Gasser

Journal article  |  2015  |  Scientific Reports

The barber's pole worm CAP protein superfamily - A basis for fundamental discovery and biotechnology advances

Namitha Mohandas, Neil D Young, Abdul Jabbar, Pasi K Korhonen, Anson V Koehler, Parisa Amani, Ross S Hall, Paul W Sternberg, Aaron R Jex, Andreas Hofmann, Robin B Gasser

Journal article  |  2015  |  Biotechnology Advances

Exploring molecular variation in Schistosoma japonicum in China

Neil D Young, Kok-Gan Chan, Pasi K Korhonen, Teik Min Chong, Robson Ee, Namitha Mohandas, Anson V Koehler, Yan-Lue Lim, Andreas Hofmann, Aaron R Jex, Baozhen Qian, Neil B Chilton, Geoffrey N Gobert, Donald P McManus, Patrick Tan, Bonnie L Webster, David Rollinson, Robin B Gasser

Journal article  |  2015  |  Scientific Reports

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites

Brendan RE Ansell, Malcolm J McConville, Louise Baker, Pasi K Korhonen, Neil D Young, Ross S Hall, Cristian AA Rojas, Staffan G Svard, Robin B Gasser, Aaron R Jex

Journal article  |  2015  |  PLOS Neglected Tropical Diseases

Deep sequencing of the uterine immune response to bacteria during the equine oestrous cycle

Christina D Marth, Neil D Young, Lisa Y Glenton, Drew M Noden, Glenn F Browning, Natali Krekeler

Journal article  |  2015  |  BMC Genomics

A practical Java tool for small-molecule compound appraisal

Parisa Amani, Todd Sneyd, Sarah Preston, Neil D Young, Lyndel Mason, Ulla-Maja Bailey, Jonathan Baell, David Camp, Robin B Gasser, Alain-Dominique Gorse, Paul Taylor, Andreas Hofmann

Journal article  |  2015  |  Journal of Cheminformatics

Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions

Clare A Anstead, Pasi K Korhonen, Neil D Young, Ross S Hall, Aaron R Jex, Shwetha C Murali, Daniel ST Hughes, Siu F Lee, Trent Perry, Andreas J Stroehlein, Brendan RE Ansell, Bert Breugelmans, Andreas Hofmann, Jiaxin Qu, Shannon Dugan, Sandra L Lee, Hsu Chao, Huyen Dinh, Yi Han, Harsha V Doddapaneni, et al.

Journal article  |  2015  |  Nature Communications

Flatworms have lost the right open reading frame kinase 3 gene during evolution

Bert Breugelmans, Brendan RE Ansell, Neil D Young, Parisa Amani, Andreas J Stroehlein, Paul W Sternberg, Aaron R Jex, Peter R Boag, Andreas Hofmann, Robin B Gasser

Journal article  |  2015  |  Scientific Reports

Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates

Mark S Pearson, Luke Becker, Patrick Driguez, Neil D Young, Soraya Gaze, Tiago Mendes, Xiao-Hong Li, Denise L Doolan, Nicholas Midzi, Takafira Mduluza, Donald P McManus, R Alan Wilson, Jeffrey M Bethony, Norman Nausch, Francisca Mutapi, Philip L Felgner, Alex Loukas

Journal article  |  2015  |  Frontiers in Immunology

New Research Tools for Urogenital Schistosomiasis

Gabriel Rinaldi, Neil D Young, Jared D Honeycutt, Paul J Brindley, Robin B Gasser, Michael H Hsieh

Journal article  |  2015  |  Journal of Infectious Diseases

Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver

Cristian A Alvarez Rojas, Brendan RE Ansell, Ross S Hall, Robin B Gasser, Neil D Young, Aaron R Jex, Jean-Pierre Y Scheerlinck

Journal article  |  2015  |  Parasites & Vectors

Genetic blueprint of the zoonotic pathogen Toxocara canis

Xing-Quan Zhu, Pasi K Korhonen, Huimin Cai, Neil D Young, Peter Nejsum, Georg von Samson-Himmelstjerna, Peter R Boag, Patrick Tan, Qiye Li, Jiumeng Min, Yulan Yang, Xiuhua Wang, Xiaodong Fang, Ross S Hall, Andreas Hofmann, Paul W Sternberg, Aaron R Jex, Robin B Gasser

Journal article  |  2015  |  Nature Communications

Prospects for Vector-Based Gene Silencing to Explore Immunobiological Features of Schistosoma mansoni

Jana Hagen, Jean-Pierre Y Scheerlinck, Neil D Young, Robin B Gasser, Bernd H Kalinna

Journal article  |  2015  |  Advances in Parasitology

Mitochondrial genomes of Trichinella species and genotypes - a basis for diagnosis, and systematic and epidemiological explorations

Namitha Mohandas, Edoardo Pozio, Giuseppe La Rosa, Pasi K Korhonen, Neil D Young, Anson V Koehler, Ross S Hall, Paul W Sternberg, Peter R Boag, Aaron R Jex, Bill CH Chang, Robin B Gasser

Journal article  |  2014  |  International Journal for Parasitology

Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo

Jana Hagen, Neil D Young, Alison L Every, Charles N Pagel, Corinna Schnoeller, Jean-Pierre Y Scheerlinck, Robin B Gasser, Bernd H Kalinna

Journal article  |  2014  |  Nature Communications

Support for the coevolution of Neoparamoeba and their endosymbionts, Perkinsela amoebae-like organisms

Neil D Young, Iva Dykova, Philip BB Crosbie, Matthias Wolf, Richard N Morrison, Andrew R Bridle, Barbara F Nowak

Journal article  |  2014  |  European Journal of Protistology

Proteomics elucidates key molecules involved in exsheathment in vitro in Oesophagostomum dentatum

Martina Ondrovics, Katja Silbermayr, Makedonka Mitreva, Neil D Young, Robin B Gasser, Anja Joachim

Journal article  |  2014  |  International Journal for Parasitology

Bioinformatic exploration of RIO protein kinases of parasitic and free-living nematodes

Bert Breugelmans, Aaron R Jex, Pasi K Korhonen, Stefano Mangiola, Neil D Young, Paul W Sternberg, Peter R Boag, Andreas Hofmann, Robin B Gasser

Journal article  |  2014  |  International Journal for Parasitology

First insight into CD59-like molecules of adult Fasciola hepatica

Yunliang Shi, Hayley Toet, Vignesh Rathinasamy, Neil D Young, Robin B Gasser, Travis Beddoe, Weiyi Huang, Terry W Spithill

Journal article  |  2014  |  Experimental Parasitology

The Opisthorchis viverrini genome provides insights into life in the bile duct

Neil D Young, Niranjan Nagarajan, Suling Joyce Lin, Pasi K Korhonen, Aaron R Jex, Ross S Hall, Helena Safavi-Hemami, Worasak Kaewkong, Denis Bertrand, Song Gao, Qihui Seet, Sopit Wongkham, Bin Tean Teh, Chaisiri Wongkham, Pewpan Maleewong Intapan, Wanchai Maleewong, Xinhua Yang, Min Hu, Zuo Wang, Andreas Hofmann, et al.

Journal article  |  2014  |  Nature Communications

Genome and transcriptome of the porcine whipworm Trichuris suis

Aaron R Jex, Peter Nejsum, Erich M Schwarz, Li Hu, Neil D Young, Ross S Hall, Pasi K Korhonen, Shengguang Liao, Stig Thamsborg, Jinquan Xia, Pengwei Xu, Shaowei Wang, Jean-Pierre Y Scheerlinck, Andreas Hofmann, Paul W Sternberg, Jun Wang, Robin B Gasser

Journal article  |  2014  |  Nature Genetics

Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics

Tulio DL Campos, Neil D Young, Pasi K Korhonen, Ross S Hall, Stefano Mangiola, Andrew Lonie, Robin B Gasser

Journal article  |  2014  |  Parasites & Vectors

Combined Proteomic and Transcriptomic Interrogation of the Venom Gland of Conus geographus Uncovers Novel Components and Functional Compartmentalization*

Helena Safavi-Hemami, Hao Hu, Dhana G Gorasia, Pradip K Bandyopadhyay, Paul D Veith, Neil D Young, Eric C Reynolds, Mark Yandell, Baldomero M Olivera, Anthony W Purcell

Journal article  |  2014  |  Molecular and Cellular Proteomics

Complete mitochondrial genomes of the 'intermediate form' of Fasciola and Fasciola gigantica, and their comparison with F. hepatica

Guo-Hua Liu, Robin B Gasser, Neil D Young, Hui-Qun Song, Lin Ai, Xing-Quan Zhu

Journal article  |  2014  |  Parasites & Vectors

Analysis of the transcriptome of adult Dictyocaulus filaria and comparison with Dictyocaulus viviparus, with a focus on molecules involved in host-parasite interactions

Stefano Mangiola, Neil D Young, Paul W Sternberg, Christina Strube, Pasi K Korhonen, Makedonka Mitreva, Jean-Pierre Scheerlinck, Andreas Hofmann, Aaron R Jex, Robin B Gasser

Journal article  |  2014  |  International Journal for Parasitology

Apoptosis in schistosomes: toward novel targets for the treatment of schistosomiasis

Erinna F Lee, Neil D Young, Nicholas TY Lim, Robin B Gasser, W Douglas Fairlie

Journal article  |  2014  |  Trends in Parasitology

Insights into the immuno-molecular biology of Angiostrongylus vasorum through transcriptomics-Prospects for new interventions

Brendan RE Ansell, Manuela Schnyder, Peter Deplazes, Pasi K Korhonen, Neil D Young, Ross S Hall, Stefano Mangiola, Peter R Boag, Andreas Hofmann, Paul W Sternberg, Aaron R Jex, Robin B Gasser

Journal article  |  2013  |  Biotechnology Advances

Getting the most out of parasitic helminth transcriptomes using HelmDB: Implications for biology and biotechnology

Stefano Mangiola, Neil D Young, Pasi Korhonen, Alinda Mondal, Jean-Pierre Scheerlinck, Paul W Sternberg, Cinzia Cantacessi, Ross S Hall, Aaron R Jex, Robin B Gasser

Journal article  |  2013  |  Biotechnology Advances

SOX9 Duplication Linked to Intersex in Deer

Regina Kropatsch, Gabriele Dekomien, Denis A Akkad, Wanda M Gerding, Elisabeth Petrasch-Parwez, Neil D Young, Janine Altmueller, Peter Nuernberg, Robin B Gasser, Joerg T Epplen

Journal article  |  2013  |  PLoS One

Proteomic Analysis of Oesophagostomum dentatum (Nematoda) during Larval Transition, and the Effects of Hydrolase Inhibitors on Development

Martina Ondrovics, Katja Silbermayr, Makedonka Mitreva, Neil D Young, Ebrahim Razzazi-Fazeli, Robin B Gasser, Anja Joachim

Journal article  |  2013  |  PLoS One

SchistoDB: an updated genome resource for the three key schistosomes of humans

Adhemar Zerlotini, Eric RGR Aguiar, Fudong Yu, Huayong Xu, Yixue Li, Neil D Young, Robin B Gasser, Anna V Protasio, Matthew Berriman, David S Roos, Jessica C Kissinger, Guilherme Oliveira

Journal article  |  2013  |  Nucleic Acids Research

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

Erich M Schwarz, Pasi K Korhonen, Bronwyn E Campbell, Neil D Young, Aaron R Jex, Abdul Jabbar, Ross S Hall, Alinda Mondal, Adina C Howe, Jason Pell, Andreas Hofmann, Peter R Boag, Xing-Quan Zhu, T Ryan Gregory, Alex Loukas, Brian A Williams, Igor Antoshechkin, C Titus Brown, Paul W Sternberg, Robin B Gasser

Journal article  |  2013  |  Genome Biology

Decoding the Ascaris suum Genome using Massively Parallel Sequencing and Advanced Bioinformatic Methods - Unprecedented Prospects for Fundamental and Applied Research

Aaron R Jex, Shiping Liu, Bo Li, Neil D Young, Ross S Hall, Yingrui Li, Peter Geldhof, Peter Nejsum, Paul W Sternberg, Jun Wang, Huanming Yang, Robin B Gasser

Book Chapter  |  2013

A Deep Exploration of the Transcriptome and "Excretory/Secretory" Proteome of Adult Fascioloides magna

Cinzia Cantacessi, Jason Mulvenna, Neil D Young, Martin Kasny, Petr Horak, Ammar Aziz, Andreas Hofmann, Alex Loukas, Robin B Gasser

Journal article  |  2012  |  Molecular and Cellular Proteomics

Molecular Changes in Opisthorchis viverrini (Southeast Asian Liver Fluke) during the Transition from the Juvenile to the Adult Stage

Aaron R Jex, Neil D Young, Jittiyawadee Sripa, Ross S Hall, Jean-Pierre Scheerlinck, Thewarach Laha, Banchob Sripa, Robin B Gasser

Journal article  |  2012  |  PLoS Neglected Tropical Diseases

Harnessing Genomic Technologies to Explore the Molecular Biology of Liver Flukes-Major Implications for Fundamental and Applied Research

ND Young, AR Jex, C Cantacessi, BE Campbell, RB Gasser

Book Chapter  |  2012

Recent Progress in Transcriptomics of Key Gastrointestinal Nematodes of Animals - Fundamental Research Toward New Intervention Strategies

C Cantacessi, BE Campbell, AR Jex, RS Hall, ND Young, MJ Nolan, RB Gasser

Book Chapter  |  2012

Description of an Atlantic salmon (Salmo salar L.) type II interleukin-1 receptor cDNA and analysis of interleukin-1 receptor expression in amoebic gill disease-affected fish

RN Morrison, ND Young, BF Nowak

Journal article  |  2012  |  Fish and Shellfish Immunology

Bioinformatics meets parasitology

C Cantacessi, BE Campbell, AR Jex, ND Young, RS Hall, S Ranganathan, RB Gasser

Journal article  |  2012  |  Parasite Immunology

Insights into SCP/TAPS Proteins of Liver Flukes Based on Large-Scale Bioinformatic Analyses of Sequence Datasets

Cinzia Cantacessi, Andreas Hofmann, Neil D Young, Ursula Broder, Ross S Hall, Alex Loukas, Robin B Gasser

Journal article  |  2012  |  PLoS One

Whole-genome sequence of Schistosoma haematobium

Neil D Young, Aaron R Jex, Bo Li, Shiping Liu, Linfeng Yang, Zijun Xiong, Yingrui Li, Cinzia Cantacessi, Ross S Hall, Xun Xu, Fangyuan Chen, Xuan Wu, Adhemar Zerlotini, Guilherme Oliveira, Andreas Hofmann, Guojie Zhang, Xiaodong Fang, Yi Kang, Bronwyn E Campbell, Alex Loukas, et al.

Journal article  |  2012  |  Nature Genetics

Ascaris suum draft genome

Aaron R Jex, Shiping Liu, Bo Li, Neil D Young, Ross S Hall, Yingrui Li, Linfeng Yang, Na Zeng, Xun Xu, Zijun Xiong, Fangyuan Chen, Xuan Wu, Guojie Zhang, Xiaodong Fang, Yi Kang, Garry A Anderson, Todd W Harris, Bronwyn E Campbell, Johnny Vlaminck, Tao Wang, et al.

Journal article  |  2011  |  Nature

Exploring the Fasciola hepatica tegument proteome

R Alan Wilson, Janelle M Wright, William de Castro-Borges, Sophie J Parker-Manuel, Adam A Dowle, Peter D Ashton, Neil D Young, Robin B Gasser, Terry W Spithill

Journal article  |  2011  |  International Journal for Parasitology

Specialisation of the Venom Gland Proteome in Predatory Cone Snails Reveals Functional Diversification of the Conotoxin Biosynthetic Pathway

Helena Safavi-Hemami, William A Siero, Dhana G Gorasia, Neil D Young, David MacMillan, Nicholas A Williamson, Anthony W Purcell

Journal article  |  2011  |  Journal of Proteome Research

RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini

Jittiyawadee Sripa, Porntip Pinlaor, Paul J Brindley, Banchob Sripa, Sasithorn Kaewkes, Mark W Robinson, Neil D Young, Robin B Gasser, Alex Loukas, Thewarach Laha

Journal article  |  2011  |  Parasitology International

The Transcriptome of Trichuris suis - First Molecular Insights into a Parasite with Curative Properties for Key Immune Diseases of Humans

Cinzia Cantacessi, Neil D Young, Peter Nejsum, Aaron R Jex, Bronwyn E Campbell, Ross S Hall, Stig M Thamsborg, Jean-Pierre Scheerlinck, Robin B Gasser

Journal article  |  2011  |  PLoS One

Deep insights into Dictyocaulus viviparus transcriptomes provides unique prospects for new drug targets and disease intervention

Cinzia Cantacessi, Robin B Gasser, Christina Strube, Thomas Schnieder, Aaron R Jex, Ross S Hall, Bronwyn E Campbell, Neil D Young, Shoba Ranganathan, Paul W Sternberg, Makedonka Mitreva

Journal article  |  2011  |  Biotechnology Advances

A Portrait of the Transcriptome of the Neglected Trematode, Fasciola gigantica-Biological and Biotechnological Implications

Neil D Young, Aaron R Jex, Cinzia Cantacessi, Ross S Hall, Bronwyn E Campbell, Terence W Spithill, Sirikachorn Tangkawattana, Prasarn Tangkawattana, Thewarach Laha, Robin B Gasser

Journal article  |  2011  |  PLoS Neglected Tropical Diseases

Amoebic gill disease (AGD) in Atlantic salmon (Salmo salar) farmed in Chile

Patricio A Bustos, Neil D Young, Marco A Rozas, Harry M Bohle, Ricardo S Ildefonso, Richard N Morrison, Barbara F Nowak

Journal article  |  2011  |  Aquaculture

Infection with the carcinogenic human liver fluke, Opisthorchis viverrini

Michael J Smout, Banchob Sripa, Thewarach Laha, Jason Mulvenna, Robin B Gasser, Neil D Young, Jeffrey M Bethony, Paul J Brindleye, Alex Loukas

Journal article  |  2011  |  Molecular BioSystems

Cryptic Parasite Revealed: Improved Prospects for Treatment and Control of Human Cryptosporidiosis Through Advanced Technologies

Aaron R Jex, Huw V Smith, Matthew J Nolan, Bronwyn E Campbell, Neil D Young, Cinzia Cantacessi, Robin B Gasser

Journal article  |  2011  |  Advances in Parasitology

Soil-Transmitted Helminths of Humans in Southeast Asia-Towards Integrated Control

Aaron R Jex, Yvonne AL Lim, Jeffrey M Bethony, Peter J Hotez, Neil D Young, Robin B Gasser

Book Chapter  |  2011  |  Advances in Parasitology

First transcriptomic analysis of the economically important parasitic nematode, Trichostrongylus colubriformis, using a next-generation sequencing approach

Cinzia Cantacessi, Makedonka Mitreva, Bronwyn E Campbell, Ross S Hall, Neil D Young, Aaron R Jex, Shoba Ranganathan, Robin B Gasser

Journal article  |  2010  |  Infection Genetics and Evolution

Progress on the transcriptomics of carcinogenic liver flukes of humans-Unique biological and biotechnological prospects

Neil D Young, Aaron R Jex, Cinzia Cantacessi, Bronwyn E Campbell, Thewarach Laha, Woon-Mok Sohn, Banchob Sripa, Alex Loukas, Paul J Brindley, Robin B Gasser

Journal article  |  2010  |  Biotechnology Advances

Proteomic Interrogation of Venom Delivery in Marine Cone Snails: Novel Insights into the Role of the Venom Bulb

Helena Safavi-Hemami, Neil D Young, Nicholas A Williamson, Anthony W Purcell

Journal article  |  2010  |  Journal of Proteome Research

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing

Cinzia Cantacessi, Aaron R Jex, Ross S Hall, Neil D Young, Bronwyn E Campbell, Anja Joachim, Matthew J Nolan, Sahar Abubucker, Paul W Sternberg, Shoba Ranganathan, Makedonka Mitreva, Robin B Gasser

Journal article  |  2010  |  Nucleic Acids Research

Unlocking the Transcriptomes of Two Carcinogenic Parasites, Clonorchis sinensis and Opisthorchis viverrini

Neil D Young, Bronwyn E Campbell, Ross S Hall, Aaron R Jex, Cinzia Cantacessi, Thewarach Laha, Woon-Mok Sohn, Banchob Sripa, Alex Loukas, Paul J Brindley, Robin B Gasser

Journal article  |  2010  |  PLoS Neglected Tropical Diseases

Massively Parallel Sequencing and Analysis of the Necator americanus Transcriptome

Cinzia Cantacessi, Makedonka Mitreva, Aaron R Jex, Neil D Young, Bronwyn E Campbell, Ross S Hall, Maria A Doyle, Stuart A Ralph, Elida M Rabelo, Shoba Ranganathan, Paul W Sternberg, Alex Loukas, Robin B Gasser

Journal article  |  2010  |  PLoS Neglected Tropical Diseases

Characterisation of Nitric Oxide Synthase in Three Cnidarian-Dinoflagellate Symbioses

Helena Safavi-Hemami, Neil D Young, Jason Doyle, Lyndon Llewellyn, Anke Klueter

Journal article  |  2010  |  PLoS One

Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortus

Cinzia Cantacessi, Bronwyn E Campbell, Neil D Young, Aaron R Jex, Ross S Hall, Paul JA Presidente, Jodi L Zawadzki, Weiwei Zhong, Boanerges Aleman-Meza, Alex Loukas, Paul W Sternberg, Robin B Gasser

Journal article  |  2010  |  BMC Genomics

Elucidating the transcriptome of Fasciola hepatica - A key to fundamental and biotechnological discoveries for a neglected parasite

Neil D Young, Ross S Hall, Aaron R Jex, Cinzia Cantacessi, Robin B Gasser

Journal article  |  2010  |  Biotechnology Advances

Analysis of nucleotide variation within the triose-phosphate isomerase gene of Giardia duodenalis from sheep and its zoonotic implications

Matthew J Nolan, Aaron R Jex, Aradhana Pangasa, Neil D Young, Angus J Campbell, Melita Stevens, Robin B Gasser

Journal article  |  2010  |  Electrophoresis

In situ stress testing to identify Australian black tiger prawns (Penaeus monodon) free of gill-associated virus and Mourilyan virus

JA Cowley, GJ Coman, ML Salmon, ND Young, KV Rajendran, KJ Wilson, NP Preston

Journal article  |  2009  |  Australian Veterinary Journal

Coordinated down-regulation of the antigen processing machinery in the gills of amoebic gill disease-affected Atlantic salmon (Salmo salar L.)

ND Young, GA Cooper, BF Nowak, BF Koop, RN Morrison

Journal article  |  2008  |  Molecular Immunology

Development of a diagnostic PCR to detect Neoparamoeba perurans, agent of amoebic gill disease

ND Young, I Dykova, BF Nowak, RN Morrison

Journal article  |  2008  |  Journal of Fish Diseases

Neoparamoeba perurans is a cosmopolitan aetiological agent of amoebic gill disease

Neil D Young, Iva Dykova, Kevin Snekvik, Barbara F Nowak, Richard N Morrison

Journal article  |  2008  |  Diseases of Aquatic Organisms

Neoparamoeba perurans n. sp., an agent of amoebic gill disease of Atlantic salmon (Salmo salar)

ND Young, PBB Crosbie, MB Adams, BF Nowak, RN Morrison

Journal article  |  2007  |  International Journal for Parasitology

Microbial community dynamics in a larval aquaculture system of the tropical rock lobster, Panulirus ornatus

DG Bourne, N Young, N Webster, M Payne, M Salmon, S Demel, M Hall

Journal article  |  2004  |  Aquaculture