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Dr

James Dowty

Statistician (Mega)
Melbourne School of Population and Global Health
science & technology
life sciences & biomedicine
cancer
prevention
genetics
oncology
clinical research
breast cancer
2 aetiology
James Dowty's Profile Picture
Dr

James Dowty

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Genetic epidemiology
James Dowty's Profile Picture
Dr

James Dowty

 
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Projects

Displaying the 10 most recent projects from 11 for James Dowty.

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Evidence-based translation of epigenetic testing to increase the precision of prostate cancer risk and progression prediction

2019 - 2022
Completed
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HERITABLE METHYLATION MARKS ASSOCIATED WITH COLORECTAL CANCER RISK

2019 - 2022
Completed
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Heritable epigenetic risk factors for prostate cancer.

2017 - 2019
Completed
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WHAT IS THE RISK OF CANCER FOR MUTATION CARRIERS?

People with the genetic Lynch syndrome are more likely to get cancer but we cannot accurately predict who will get cancer and when. Doctors ..

2014 - 2016
Completed
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Do the effects of the environment and lifestyle on a woman's risk of breast cancer depend on her underlying genetic and familial susceptibility?

This study will provide new and credible information on how the effects of environmental and lifestyle factors on breast cancer risk depend ..

2011 - 2014
Completed
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Cancer and low-dose radiation - possible effects of CT scans in childhood

Despite 100 years of research there is uncertainty about effects of low dose radiation from background and medical X-rays. We will measure t..

2008 - 2013
Completed
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Discovering new genes for bowel cancer

Our aim is to discover new genes that greatly increase bowel cancer risk. If we can identify these carriers we may be able to prevent them g..

2010 - 2013
Completed
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Translational research to better use genetic testing to reduce the morbidity and mortality of breast cancer in Victoria

2009 - 2013
Completed
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Translational research to better use genetic testing to reduce the morbidity and mortality of breast cancer in Victoria

2009 - 2013
Completed
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How do your genes affect your risk of allergic diseases?

It is biologically plausible that the association of known environmental risk factors for asthma may be different for genetically susceptibl..

2010 - 2012
Completed

11

Projects

Project Types

11

Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works from 111 for James Dowty.

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Update of penetrance estimates in Birt-Hogg-Dubé syndrome.

Fiona Jane Bruinsma, James G Dowty, Aung Ko Win, Laura C Goddard, Prachi Agrawal, Domenico Attina', Nabil Bissada, Monica De Luise, Daniel B Eisen, Mitsuko Furuya, Giuseppe Gasparre, Maurizio Genuardi, Anne-Marie Gerdes, Thomas Van Overeem Hansen, Arjan C Houweling, Paul Christiaan Johannesma, André Lencastre, Derek Lim, Noralane M Lindor, Valentina Luzzi, et al.

Journal article  |  2023  |  J Med Genet

BACKGROUND: Birt-Hogg-Dubé (BHD) syndrome is a rare genetic syndrome caused by pathogenic or likely pathogenic germline variants i..

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Heritable methylation marks associated with prostate cancer risk.

James G Dowty, Chenglong Yu, Mahnaz Hosseinpour, Jihoon Eric Joo, Ee Ming Wong, Tu Nguyen-Dumont, Joseph Rosenbluh, Graham G Giles, Roger L Milne, Robert J MacInnis, Pierre-Antoine Dugué, Melissa C Southey

Journal article  |  2023  |  Fam Cancer

DNA methylation marks that are inherited from parents to offspring are known to play a role in cancer risk and could explain part ..

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The CRISP Trial: RCT of a decision support tool for risk-stratified colorectal cancer screening

Jon Emery, Mark A Jenkins, Sibel Saya, Patty Chondros, Jasmeen Oberoi, Shakira Milton, Kitty Novy, Emily Habgood, Napin Karnchanachari, Marie Pirotta, Lyndal Trevena, Adrian Bickerstaffe, Richard de Abreu Lourenco, Crothers Anna, Driss Ait Ouakrim, Louisa Flander, James G Dowty, Fiona M Walter, Malcolm Clark, Sally Doncovio, et al.

Journal article  |  2023  |  British Journal of General Practice

Background: A risk-stratified approach to colorectal cancer (CRC) screening could result in more acceptable balance of benefits an..

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Psychiatric genetic counseling: A survey of Australian genetic counselors' practice and attitudes

Joanne Isbister, Adrienne Sexton, Laura E Forrest, Paul James, James Dowty, Jessica Taylor, Jehannine Austin, Ingrid Winship

Journal article  |  2022  |  JOURNAL OF GENETIC COUNSELING

Genetic counseling plays a critical role in supporting individuals and their families' adaption to psychiatric conditions, address..

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Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Pal Moller, Toni Seppala, James G Dowty, Saskia Haupt, Mev Dominguez-Valentin, Lone Sunde, Inge Bernstein, Christoph Engel, Stefan Aretz, Maartje Nielsen, Gabriel Capella, Dafydd Gareth Evans, John Burn, Elke Holinski-Feder, Lucio Bertario, Bernardo Bonanni, Annika Lindblom, Zohar Levi, Finlay Macrae, Ingrid Winship, et al.

Journal article  |  2022  |  HEREDITARY CANCER IN CLINICAL PRACTICE

OBJECTIVE: To compare colorectal cancer (CRC) incidences in carriers of pathogenic variants of the MMR genes in the PLSD and IMRC ..

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Novel Germline Mutations in a Cohort of Men with Familial Prostate Cancer

Romy Mondschein, Damien Bolton, David Clouston, James Dowty, Liam Kavanagh, Declan Murphy, Prudence Scott, Renea A Taylor, Heather Thorne

Journal article  |  2022  |  CANCERS

Background: Germline mutations in BRCA2 are associated with aggressive prostate cancer. Additional information regarding the clini..

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Genetic Aspects of Mammographic Density Measures Associated with Breast Cancer Risk

Shuai Li, Tuong L Nguyen, Nguyen-Dumont Tu, James G Dowty, Gillian S Dite, Zhoufeng Ye, Ho N Trinh, Christopher F Evans, Maxine Tan, Joohon Sung, Mark A Jenkins, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2022  |  CANCERS

Cumulus, Altocumulus, and Cirrocumulus are measures of mammographic density defined at increasing pixel brightness thresholds, whi..

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MP58-13 ATM MUTATIONS ARE ASSOCIATED WITH HIGH-RISK ARCHITECTURAL FEATURES IN MEN WITH FAMILIAL PROSTATE CANCER

Romy Mondschein, Bolton Damien, David Clouston, Declan Murphy, Prudence Scott, Renea Taylor, James Dowty, Heather Thorne

Journal article  |  2022  |  Journal of Urology

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Population-based estimates of age-specific cumulative risk of breast cancer for pathogenic variants in ATM

Anne-Laure Renault, James G Dowty, Jason A Steen, Shuai Li, Ingrid M Winship, Graham G Giles, John L Hopper, Melissa C Southey, Tu Nguyen-Dumont

Journal article  |  2022  |  BREAST CANCER RESEARCH

BACKGROUND: Multigene panel tests for breast cancer predisposition routinely include ATM as it is now a well-established breast ca..

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Association between maternal adversity, DNA methylation, and cardiovascular health of offspring: a longitudinal analysis of the ALSPAC cohort study

Natalie K Hyde, James G Dowty, Anna Scovelle, Gregory Armstrong, Georgina Sutherland, Lisa Olive, Kate Lycett, Adrienne O'Neil

Journal article  |  2022  |  BMJ OPEN

OBJECTIVES: Maternal adversity during pregnancy has been shown to be associated with some health outcomes in the offspring. This s..

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Scholarly Works

Keyword Analysis

Oncology and Carcinogenesis
Clinical Health
Epidemiology
Expanding Knowledge
Specific Population Health (excl. Indigenous Health)
Public Health
Health Services and Systems
Clinical Sciences
Statistics
Genetics

News

Displaying the 1 most recent news article from 1 for James Dowty.

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Filling in the genetic blanks of breast cancer predisposition

Eric Joo, James Dowty, Melissa Southey

A prolonged and focused research effort identified the breast cancer predisposition genes BRCA1 and BRCA2 in the mid 1990s, revealing mutat..

November 23, 2017
pursuit Article

1

News Articles

Credentials

Positions

Statistician (Mega)

Melbourne School of Population and Global Health

Education

Master of Science

University of Melbourne

Doctor of Pholosophy

University of Melbourne

Bachelor of Science (Honours)

University of Melbourne

Bachelor of Science

University of Melbourne

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