Sacha Pidot

Endofungal bacteria boost anthelminthic host protection with the biosurfactant symbiosin

Hannah Buettner, Sacha J Pidot, Kirstin Scherlach, Christian Hertweck

Journal article  |  2022  |  CHEMICAL SCIENCE

Effective protection of soil fungi from predators is crucial for their survival in the niche. Thus, fungi have developed efficient..

A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides.

Sarah P Niehs, Kirstin Scherlach, Benjamin Dose, Zerrin Uzum, Timothy P Stinear, Sacha J Pidot, Christian Hertweck

Journal article  |  2022  |  PNAS Nexus

The tight association of the pathogenic fungus Rhizopus microsporus and its toxin-producing, bacterial endosymbionts (Mycetohabita..

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria.

Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Shabbir Ahmed, Desalegne Abebew, Nicholas J Tobias, Peter Grün, Jan J Crames, Laura Pöschel, Wolfgang Kuttenlochner, Christian Richter, Jennifer Herrmann, Rolf Müller, Aunchalee Thanwisai, Sacha J Pidot, Timothy P Stinear, Michael Groll, Yonggyun Kim, Helge B Bode

Journal article  |  2022  |  Nat Chem

Microorganisms contribute to the biology and physiology of eukaryotic hosts and affect other organisms through natural products. X..

Genome sequences of Arthrobacter spp. that use a modified sulfoglycolytic Embden-Meyerhof-Parnas pathway

Arashdeep Kaur, Phillip L van der Peet, Janice W-Y Mui, Marion Herisse, Sacha Pidot, Spencer J Williams

Journal article  |  2022  |  ARCHIVES OF MICROBIOLOGY

Sulfoglycolysis pathways enable the breakdown of the sulfosugar sulfoquinovose and environmental recycling of its carbon and sulfu..

Lithography-free synthesis of periodic, vertically-aligned, multi-walled carbon nanotube arrays

Ruiting Chen, Yafei Xue, Xinyue Xu, Hui Yang, Tengfei Qiu, Lingling Shui, Xin Wang, Guofu Zhou, Michael Giersig, Sacha Pidot, James A Hutchison, Eser Metin Akinoglu

Journal article  |  2022  |  NANOTECHNOLOGY

Until now, the growth of periodic vertically aligned multi-walled carbon nanotube (VA-MWCNT) arrays was dependent on at least one ..

Mobilization of cryptic antibiotic biosynthesis loci from human-pathogenic Nocardia.

Marion Herisse, Sacha J Pidot

Book Chapter  |  2022  |  Methods in Enzymology

The cloning and heterologous expression of natural product biosynthetic gene clusters has helped to identify many new bioactive mo..

Bacterial endosymbionts protect beneficial soil fungus from nematode attack

Hannah Buettner, Sarah P Niehs, Koen Vandelannoote, Zoltan Cseresnyes, Benjamin Dose, Ingrid Richter, Ruman Gerst, Marc Thilo Figge, Timothy P Stinear, Sacha J Pidot, Christian Hertweck

Journal article  |  2021  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fungi of the genus Mortierella occur ubiquitously in soils where they play pivotal roles in carbon cycling, xenobiont degradation,..

Accessible Platform for High-Throughput COVID-19 Molecular Diagnostics and Genome Sequencing Using a Repurposed 3D Printer for RNA Extraction

Koen Vandelannoote, Andrew H Buultjens, Lucy Li, Liam K Sharkey, Marion Herisse, Sacha J Pidot, Hoang Tuyet, Benjamin P Howden, Ian R Monk, Torsten Seemann, Jean YH Lee, Timothy P Stinear

Journal article  |  2021  |  ACS BIOMATERIALS SCIENCE & ENGINEERING

The COVID-19 pandemic has exposed the dependence of diagnostic laboratories on a handful of large corporations with market monopol..

Multi-Omic Analysis of Symbiotic Bacteria Associated With Aedes aegypti Breeding Sites

Katherine D Mosquera, Luis E Martinez Villegas, Sacha J Pidot, Chinhda Sharif, Sven Klimpel, Timothy P Stinear, Luciano A Moreira, Nicholas J Tobias, Marcelo G Lorenzo

Journal article  |  2021  |  FRONTIERS IN MICROBIOLOGY

Mosquito breeding sites are complex aquatic environments with wide microbial diversity and physicochemical parameters that can cha..

Microfluidics Reveals Trapping of Endosymbiotic Bacteria Inside a Fungus

Ingrid Richter, Zerrin Uzum, Calire Stanley, Sacha Pidot, Christian Hertweck

Conference Proceedings  |  2021  |  Proceedings of the Emerging Investigators in Microfluidics Conference