Freya Sheeran

Adaptations in Protein Expression and Regulated Activity Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure

Freya L Sheeran, Julie Angerosa, Norman Y Liaw, Michael M Cheung, Salvatore Pepe

Journal article  |  2019  |  Oxidative Medicine and Cellular Longevity

Mitochondrial Bioenergetics and Dysfunction in Failing Heart.

Freya L Sheeran, Salvatore Pepe

Book Chapter  |  2017  |  Advances in Experimental Medicine and Biology

Energy insufficiency has been recognized as a key feature of systolic heart failure. Although mitochondria have long been known to..

Posttranslational modifications and dysfunction of mitochondrial enzymes in human heart failure.

Freya L Sheeran, Salvatore Pepe

Journal article  |  2016  |  American Journal of Physiology-Endocrinology and Metabolism

Deficiency of energy supply is a major complication contributing to the syndrome of heart failure (HF). Because the concurrent act..

Molecular markers of programmed cell death in donor hearts before transplantation

Silvana F Marasco, Freya L Sheeran, Krishanu Chaudhuri, Matthew Vale, Michael Bailey, Salvatore Pepe

Journal article  |  2014  |  The Journal of Heart and Lung Transplantation

Remote ischemic preconditioning in cyanosed neonates undergoing cardiopulmonary bypass: A randomized controlled trial

Bryn O Jones, Salvatore Pepe, Freya L Sheeran, Susan Donath, Pollyanna Hardy, Lara Shekerdemian, Daniel J Penny, Ian McKenzie, Stephen Horton, Christian P Brizard, Yves d'Udekem, Igor E Konstantinov, Michael MH Cheung

Journal article  |  2013  |  Journal of Thoracic and Cardiovascular Surgery

Postnatal shifts in ischemic tolerance and cell survival signaling in murine myocardium

Norman Y Liaw, Louise See Hoe, Freya L Sheeran, Jason N Peart, John P Headrick, Michael MH Cheung, Salvatore Pepe

Journal article  |  2013  |  American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

Effect of Remote Ischemic Preconditioning on Phosphorylated Protein Signaling in Children Undergoing Tetralogy of Fallot Repair: A Randomized Controlled Trial

Salvatore Pepe, Norman Y Liaw, Michele Hepponstall, Freya L Sheeran, Matthew S Yong, Yves d'Udekem, Michael M Cheung, Igor E Konstantinov

Journal article  |  2013  |  Journal of the American Heart Association

Oxidation of Myofibrillar Proteins in Human Heart Failure

Marcella Canton, Sara Menazza, Freya L Sheeran, Patrizia Polverino de laureto, Fabio Di Lisa, Salvatore Pepe

Journal article  |  2011  |  Journal of the American College of Cardiology

Mitochondrial dysfunction in CD4 lymphocytes from stavudine-treated HIV patients

Lloyd Einsiedel, Catherine L Cherry, Freya L Sheeran, Anna Friedhuber, Steve L Wesselingh, Salvatore Pepe

Journal article  |  2010  |  Mitochondrion

Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium

Freya L Sheeran, Jan Rydstrom, Mikhail I Shakhparonov, Nikolay B Pestov, Salvatore Pepe

Journal article  |  2010  |  Biochimica et Biophysica Acta - General Subjects