Andrew Kompa

Sphingolipid imbalance and inflammatory effects induced by uremic toxins in heart and kidney cells are reversed by dihydroceramide desaturase 1 inhibition

Feby Savira, Ruth Magaye, Carmen Scullino, Bernard L Flynn, Stuart M Pitson, Dovile Anderson, Darren J Creek, Yue Hua, Xin Xiong, Li Huang, Danny Liew, Christopher Reid, David Kaye, Andrew R Kompa, Bing Hui Wang

Journal article  |  2021  |  TOXICOLOGY LETTERS

Non-dialysable protein-bound uremic toxins (PBUTs) contribute to the development of cardiovascular disease (CVD) in chronic kidney..

The impact of coronary heart disease prevention on work productivity: a 10-year analysis.

Feby Savira, Bing H Wang, Andrew R Kompa, Zanfina Ademi, Alice J Owen, Danny Liew, Ella Zomer

Journal article  |  2021  |  Eur J Prev Cardiol

AIMS: To determine the impact of preventing new (incident) cases of coronary heart disease (CHD) on years of life and productivity..

Apoptosis signal-regulating kinase 1 inhibition reverses deleterious indoxyl sulfate-mediated endothelial effects

Feby Savira, Andrew R Kompa, Ruth Magaye, Xin Xiong, Li Huang, Beat M Jucker, Robert N Willette, Darren J Kelly, Bing H Wang

Journal article  |  2021  |  LIFE SCIENCES

AIMS: Indoxyl sulfate (IS), a protein-bound uremic toxin, is implicated in endothelial dysfunction, which contributes to adverse c..

The impact of coronary heart disease prevention on work productivity: a 10-year analysis

Feby Savira, Bing H Wang, Andrew R Kompa, Zanfina Ademi, Alice J Owen, Danny Liew, Ella Zomer

Journal article  |  2021  |  EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY

AIM: To assess the cost-effectiveness of dapagliflozin in addition to standard care versus standard care alone in patients with ch..

The Preventable Productivity Burden of Kidney Disease in Australia.

Feby Savira, Zanfina Ademi, Bing H Wang, Andrew R Kompa, Alice J Owen, Danny Liew, Ella Zomer

Journal article  |  2021  |  J Am Soc Nephrol

BACKGROUND: Kidney disease is associated with impaired work productivity. However, the collective effect of missed work days, redu..

Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction

Andrew R Kompa, David W Greening, Anne M Kong, Paul J McMillan, Haoyun Fang, Ritika Saxena, Raymond CB Wong, Jarmon G Lees, Priyadharshini Sivakumaran, Andrew E Newcomb, Bakhos A Tannous, Cameron Kos, Lina Mariana, Thomas Loudovaris, Derek J Hausenloy, Shiang Y Lim

Journal article  |  2021  |  CARDIOVASCULAR RESEARCH

AIMS: To establish pre-clinical proof of concept that sustained subcutaneous delivery of the secretome of human cardiac stem cells..

RE: Blockade of apoptosis signal-regulating kinase 1 ameliorates cardiac dysfunction in cardiorenal syndrome via enhancing angiogenesis

Feby Savira, Andrew R Kompa, Amanda J Edgley, Beat M Jucker, Robert N Willette, Darren J Kelly, Bing H Wang

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF CARDIOLOGY

RE: Inhibition of apoptosis signal-regulating kinase 1 might be a novel therapeutic target in the treatment of cardiorenal syndrome

Feby Savira, Amanda J Edgley, Beat M Jucker, Robert N Willette, Henry Krum, Darren J Kelly, Andrew R Kompa, Bing H Wang

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF CARDIOLOGY

Cost-effectiveness of dapagliflozin in chronic heart failure: an analysis from the Australian healthcare perspective

F Savira, BH Wang, AR Kompa, Z Ademi, A Owen, A Tonkin, S Zoungas, D Liew, E Zomer

Conference Proceedings  |  2020  |  EUROPEAN HEART JOURNAL

Abstract Background The Dapagliflozin and Prevention of Adverse Outcomes in He..

The impact of coronary heart disease on productivity in Australia over ten years

F Savira, BH Wang, AR Kompa, Z Ademi, A Owen, D Liew, E Zomer

Conference Proceedings  |  2020  |  EUROPEAN HEART JOURNAL

Abstract Background Coronary heart disease (CHD) is the highest individual dis..