Rick Liu

Proopiomelanocortin gene delivery induces apoptosis in melanoma through NADPH oxidase 4-mediated ROS generation (vol 70, pg 14, 2014)

Guei-Sheung Liu, Jian-Ching Wu, Han-En Tsai, Gregory J Dusting, Elsa C Chan, Chieh-Shan Wu, Ming-Hong Tai

Journal article  |  2021  |  FREE RADICAL BIOLOGY AND MEDICINE

The authors regret the omission of one of the affiliations of Chieh-Shan Wu. Authors: Guei-Sheung Liu a,b,1, Jian-Ching Wu c,1, Ha..

Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update

Fan-Li Lin, Peng-Yuan Wang, Yu-Fan Chuang, Jiang-Hui Wang, Vickie HY Wong, Bang Bui, Guei-Sheung Liu

Journal article  |  2020  |  MOLECULAR THERAPY

Aberrant growth of blood vessels (neovascularization) is a key feature of severe eye diseases that can cause legal blindness, incl..

A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization

Jinying Chen, Fan-Li Lin, Jacqueline YK Leung, Leilei Tu, Jiang-Hui Wang, Yu-Fan Chuang, Fan Li, Hsin-Hui Shen, Gregory J Dusting, Vickie HY Wong, Leszek Lisowski, Alex W Hewitt, Bang V Bui, Jingxiang Zhong, Guei-Sheung Liu

Journal article  |  2020  |  ANGIOGENESIS

Gene therapies that chronically suppress vascular endothelial growth factor (VEGF) represent a new approach for managing retinal v..

Comparison of CRISPR/Cas Endonucleases forin vivoRetinal Gene Editing

Fan Li, Kristof Wing, Jiang-Hui Wang, Chi D Luu, James A Bender, Jinying Chen, Qi Wang, Qinyi Lu, Minh Thuan Nguyen Tran, Kaylene M Young, Raymond CB Wong, Alice Pebay, Anthony L Cook, Sandy SC Hung, Guei-Sheung Liu, Alex W Hewitt

Journal article  |  2020  |  FRONTIERS IN CELLULAR NEUROSCIENCE

CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demons..

Updates on Gene Therapy for Diabetic Retinopathy

Jiang-Hui Wang, Georgina Eloise Roberts, Guei-Sheung Liu

Journal article  |  2020  |  CURRENT DIABETES REPORTS

PURPOSE OF REVIEW: Diabetic retinopathy (DR), a leading cause of visual impairment in the developed country, is characterized by v..

Topical Application of Hyaluronic Acid-RGD Peptide-Coated Gelatin/Epigallocatechin-3 Gallate (EGCG) Nanoparticles Inhibits Corneal Neovascularization via Inhibition of VEGF Production

Takuya Miyagawa, Zhi-Yu Chen, Che-Yi Chang, Ko-Hua Chen, Yang-Kao Wang, Guei-Sheung Liu, Ching-Li Tseng

Journal article  |  2020  |  PHARMACEUTICS

Neovascularization (NV) of the cornea disrupts vision which leads to blindness. Investigation of antiangiogenic, slow-release and ..

An oral bait vaccination approach for the Tasmanian devil facial tumor diseases

Andrew S Flies, Emily J Flies, Samantha Fox, Amy Gilbert, Shylo R Johnson, Guei-Sheung Liu, A Bruce Lyons, Amanda L Patchett, David Pemberton, Ruth J Pye

Journal article  |  2020  |  EXPERT REVIEW OF VACCINES

Introduction: The Tasmanian devil (Sarcophilus harrisii) is the largest extant carnivorous marsupial. Since 1996, its population h..

Development of Kaempferol-Loaded Gelatin Nanoparticles for the Treatment of Corneal Neovascularization in Mice

Yu-Lun Chuang, Hsu-Wei Fang, Aditya Ajitsaria, Ko-Hua Chen, Chen-Ying Su, Guei-Sheung Liu, Ching-Li Tseng

Journal article  |  2019  |  PHARMACEUTICS

Cornea is the transparent layer in front of the eye that does not contain blood vessels. Among eye diseases, corneal neovasculariz..

Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina

Fan Li, Sandy SC Hung, Mohd Khairul Nizam Mohd Khalid, Jiang-Hui Wang, Vicki Chrysostomou, Vickie HY Wong, Vikrant Singh, Kristof Wing, Leilei Tu, James A Bender, Alice Pebay, Anna E King, Anthony L Cook, Raymond CB Wong, Bang Bui, Alex W Hewitt, Guei-Sheung Liu

Journal article  |  2019  |  HUMAN GENE THERAPY

Safe delivery of CRISPR/Cas endonucleases remains one of the major barriers to the widespread application of in vivo genome editin..

CRISPR/Cas-mediated base editing of the AMD high-risk Y402H complement factor H variant

Alex W Hewitt, Peter Tran, Mohd Khairul Nizam Mohd Khalid, Alice Pebay, Anthony L Cook, Helena Liang, Raymond Wong, Jamie E Craig, Guei-Sheung Liu, Sandy Hung

Journal article  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE