James Ziogas

Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae

Maytham Hussein, Raad Jasim, Hakan Gocol, Mark Baker, Varsha JJ Thombare, James Ziogas, Aayush Purohit, Gauri GG Rao, Jian Li, Tony Velkov

Journal article  |  2023  |  MSPHERE

Outer membrane vesicles (OMVs) secreted by Gram-negative bacteria serve as transporters for the delivery of cargo such as virulenc..

Comparative proteomic analysis of ventricular and cisternal cerebrospinal fluid in haemorrhagic stroke patients.

Katherine Hopkins, Benjamin Price, James Ziogas, Alexios Adamides, Jonathan Mangum

Journal article  |  2023  |  J Clin Neurosci

BACKGROUND: Analysis of cerebrospinal fluid (CSF) using mass spectrometry is a relatively novel analytical tool, and comparisons o..

Trace residue identification, characterization, and longitudinal monitoring of the novel synthetic opioid beta-U10, from discarded drug paraphernalia

Henry West, John L Fitzgerald, Katherine L Hopkins, Michael G Leeming, Matthew DiRago, Dimitri Gerostamoulos, Nicolas Clark, Paul Dietze, Jonathan M White, James Ziogas, Gavin E Reid

Journal article  |  2022  |  DRUG TESTING AND ANALYSIS

Empirical data regarding dynamic alterations in illicit drug supply markets in response to the COVID-19 pandemic, including the po..

The role of haptoglobin and hemopexin in the prevention of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage: a review of current literature

Sean Griffiths, Jeremy Clark, Alexios A Adamides, James Ziogas

Journal article  |  2020  |  NEUROSURGICAL REVIEW

Delayed cerebral ischaemia (DCI) after aneurysmal subarachnoid haemorrhage (aSAH) is a major cause of mortality and morbidity. The..

Differential activation of human mast cells by the antibiotics polymyxin B and colistin

Graham Mackay, Stephanie Zhang, Nithya Fernandopulle, James Ziogas, Paul Soeding

Conference Proceedings  |  2020  |  BRITISH JOURNAL OF PHARMACOLOGY

Association between elevated cerebrospinal fluid D-dimer levels and delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage

Sujeevan Jayamanoharan, Jonathan E Mangum, Stanley Stylli, James Ziogas, Alexios A Adamides

Journal article  |  2020  |  JOURNAL OF CLINICAL NEUROSCIENCE

Delayed cerebral ischaemia (DCI) after aneurysmal subarachnoid haemorrhage (aSAH) is a major contributor to morbidity and mortalit..

FInal Report: Rapid and Precise Intelligence on Drugs Pilot (RAPID) Program

John Fitzgerald, Gavin Reid, Peter Scales, James Ziogas, Nico Clarke, Paul Dietze, Nicholas Thomson, Shaun Greene

Report  |  2020

Using high-resolution Twin-Ion Metabolite Extraction (HiTIME) mass spectrometry with stable isotope labelling to investigate the metabolism of valproic acid in vivo

Michael G Leeming, Noel Cranswick, Christine E Wright, James Ziogas, Terence J O'Brien, William A Donald, Richard AJ O'Hair

Journal article  |  2019  |  INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Valproic acid (VPA) is a medication that is widely used in the treatment of epilepsy and bipolar disorder, despite a known potenti..

Association of copeptin, a surrogate marker of arginine vasopressin, with cerebral vasospasm and delayed ischemic neurologic deficit after aneurysmal subarachnoid hemorrhage

Sandra J Fernandez, Ibraham Barakat, James Ziogas, Tony Frugier, Stanley S Stylli, John D Laidlaw, Andrew H Kaye, Alexios A Adamides

Journal article  |  2019  |  JOURNAL OF NEUROSURGERY

OBJECTIVEDelayed ischemic neurological deficit (DIND) is a leading cause of mortality and morbidity after aneurysmal subarachnoid ..

Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain-associated conditions

Maria Roitman, Laura E Edgington-Mitchell, Jon Mangum, James Ziogas, Alexios A Adamides, Paul Myles, Hearan Choo-Bunnett, Nigel W Bunnett, Jenny M Gunnersen

Journal article  |  2019  |  PAIN REPORTS

INTRODUCTION: Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain ..