Paul Whitney

Screening and development of monoclonal antibodies for identification of ferret T follicular helper cells

Wenbo Jiang, Julius Wong, Hyon-Xhi Tan, Hannah G Kelly, Paul G Whitney, Ian Barr, Daniel S Layton, Stephen J Kent, Adam K Wheatley, Jennifer A Juno

Journal article  |  2021  |  SCIENTIFIC REPORTS

The ferret is a key animal model for investigating the pathogenicity and transmissibility of important human viruses, and for the ..

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

Marcel Doerflinger, Yexuan Deng, Paul Whitney, Ranja Salvamoser, Sven Engel, Andrew J Kueh, Lin Tai, Annabell Bachem, Elise Gressier, Niall D Geoghegan, Stephen Wilcox, Kelly L Rogers, Alexandra L Garnham, Michael A Dengler, Stefanie M Bader, Gregor Ebert, Jaclyn S Pearson, Dominic De Nardo, Nancy Wang, Chenying Yang, et al.

Journal article  |  2020  |  IMMUNITY

Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necropt..

SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines

Ian G Barr, Cleve Rynehart, Paul Whitney, Julian Druce

Journal article  |  2020  |  EUROSURVEILLANCE

The advent of COVID-19, has posed a risk that human respiratory samples containing human influenza viruses may also contain SARS-C..

Dissecting the molecular mechanisms underpinning T cell help for Dendritic Cell

Elise Marie Gressier, Paul Whitney, Susanne Schmidt, Sammy Bedoui

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

The regulation of T cell responses by cytohesins

A Solomatina, F Tolksdorf, PG Whitney, IR van Driel, EL Hartland, W Kolanus

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8( ) T Cells

Annabel Bachem, Christina Makhlouf, Katrina J Binger, David P de Souza, Deidra Tull, Katharina Hochheiser, Paul G Whitney, Daniel Fernandez-Ruiz, Sabrina Dahling, Wolfgang Kastemuller, Johanna Jonsson, Elise Gressier, Andrew M Lew, Carolina Perdomo, Andreas Kupz, William Figgett, Fabienne Mackay, Moshe Oleshansky, Brendan E Russ, Ian A Parish, et al.

Journal article  |  2019  |  IMMUNITY

Interactions with the microbiota influence many aspects of immunity, including immune cell development, differentiation, and funct..

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

Christopher M Harpur, Yu Kato, Shinta T Dewi, Sanda Stankovic, Darryl N Johnson, Sammy Bedoui, Paul G Whitney, Mireille H Lahoud, Irina Caminschi, William R Heath, Andrew G Brooks, Thomas Gebhardt

Journal article  |  2019  |  JOURNAL OF IMMUNOLOGY

CD4+ T cell responses are crucial for the control of many intracellular pathogens, yet the requirements for their induction are no..

Unexpected overlapping roles of multiple caspases and programmed cell death pathways in the response to bacterial infection

Ranja Salvamoser, Paul G Whitney, Marcel Doerflinger, Sammy Bedoui, Andreas Strasser, Clare Bryant, Marco J Herold

Conference Proceedings  |  2019  |  CELL DEATH DISCOVERY

Optimal protection against Salmonella infection requires noncirculating memory

Joseph M Benoun, Newton G Peres, Nancy Wang, Oanh H Pham, Victoria L Rudisill, Zachary N Fogassy, Paul G Whitney, Daniel Fernandez-Ruiz, Thomas Gebhardt, Pham Quynh-Mai, Lynn Puddington, Sammy Bedoui, Richard A Strugnell, Stephen J McSorley

Journal article  |  2018  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

While CD4 Th1 cells are required for resistance to intramacrophage infections, adoptive transfer of Th1 cells is insufficient to p..

Effective Priming of Herpes Simplex Virus-Specific CD8( ) T Cells In Vivo Does Not Require Infected Dendritic Cells

Paul G Whitney, Christina Makhlouf, Beth MacLeod, Joel Z Ma, Elise Gressier, Marie Greyer, Katharina Hochheiser, Annabell Bachem, Ali Zaid, David Voehringer, William R Heath, Mayura V Wagle, Ian Parish, Tiffany A Russell, Stewart A Smith, David C Tscharke, Thomas Gebhardt, Sammy Bedoui

Journal article  |  2018  |  JOURNAL OF VIROLOGY

Resolution of virus infections depends on the priming of virus-specific CD8+ T cells by dendritic cells (DC). While this process r..