Sue-Anne McLachlan

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

Iris Kramer, Maartje J Hooning, Nasim Mavaddat, Michael Hauptmann, Renske Keeman, Ewout W Steyerberg, Daniele Giardiello, Antonis C Antoniou, Paul DP Pharoah, Sander Canisius, Zumuruda Abu-Ful, Irene L Andrulis, Hoda Anton-Culver, Kristan J Aronson, Annelie Augustinsson, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, et al.

Journal article  |  2020  |  American Journal of Human Genetics

Previous research has shown that polygenic risk scores (PRSs) can be used to stratify women according to their risk of developing ..

107P Safety and efficacy of trifluridine/tipiracil (FTD/TPI) in previously treated metastatic colorectal cancer (mCRC): Results from the Australian cohort of the phase IIIb, international, open-label, early-access PRECONNECT study

TJ Price, M Burge, L Chantrill, YJ Chua, L Horvath, S-A McLachlan, N Pavlakis, J Shapiro, S Thavaneswaran, B Tran, D Yip, G Tancock

Conference Proceedings  |  2020  |  Annals of Oncology

Surviving glioblastoma and a sense of disconnection

L Gately, SA McLachlan, A Dowling, J Philip

Journal article  |  2020  |  Journal of Clinical Neuroscience

Given the poor prognosis of glioblastoma, little focus has been placed on the needs of long-term survivors (those alive at least t..

Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium

Hongyan Li, Mary Beth Terry, Antonis C Antoniou, Kelly-Anne Phillips, Karin Kast, Thea M Mooij, Christoph Engel, Catherine Nogues, Dominique Stoppa-Lyonnet, Christine Lasset, Pascaline Berthet, Veronique Mari, Olivier Caron, Daniel Barrowdale, Debra Frost, Carole Brewer, D Gareth Evans, Louise Izatt, Lucy Side, Lisa Walker, et al.

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: Tobacco smoking and alcohol consumption have been intensively studied in the general population to assess their effect..

Impact of type 2 diabetes on hospitalization and mortality in people with malignancy

KV Kiburg, GM Ward, S Vogrin, K Steele, E Mulrooney, M Loh, SA McLachlan, V Sundararajan, RJ MacIsaac

Journal article  |  2020  |  Diabetic Medicine

AIM: To compare the characteristics of and outcomes for people with malignancies with and without a co-diagnosis of diabetes. METH..

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R Barnes, Jamie Allen, Siddhartha Kar, Karen A Pooley, Joe Dennis, Kyriaki Michailidou, Constance Turman, Penny Soucy, Audrey Lemacon, Michael Lush, Jonathan P Tyrer, Maya Ghoussaini, Mahdi Moradi Marjaneh, Xia Jiang, Simona Agata, Kristiina Aittomaki, M Rosario Alonso, et al.

Journal article  |  2020  |  Nature Genetics

Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underl..

Alcohol consumption, cigarette smoking, and familial breast cancer risk: findings from the Prospective Family Study Cohort (ProF-SC)

Nur Zeinomar, Julia A Knight, Jeanine M Genkinger, Kelly-Anne Phillips, Mary B Daly, Roger L Milne, Gillian S Dite, Rebecca D Kehm, Yuyan Liao, Melissa C Southey, Wendy K Chung, Graham G Giles, Sue-Anne McLachlan, Michael L Friedlander, Prue C Weideman, Gord Glendon, Stephanie Nesci, Irene L Andrulis, Saundra S Buys, Esther M John, et al.

Journal article  |  2019  |  Breast Cancer Research

BACKGROUND: Alcohol consumption and cigarette smoking are associated with an increased risk of breast cancer (BC), but it is uncle..

Community knowledge of and attitudes to palliative care: A descriptive study

Anna Collins, Sue-Anne McLachlan, Jennifer Philip

Journal article  |  2019  |  Palliative Medicine

BACKGROUND: Palliative care is predominantly accessed late in the course of an illness, despite evidence to suggest the benefits o..

Development and validation of a targeted gene sequencing panel for application to disparate cancers

Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, undefined kConFab, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, et al.

Journal article  |  2019  |  Scientific Reports

Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology ..

How can digital health be used to improve outcomes in pancreatic ductal adenocarcinoma (PDAC)? Examining the potential of the PURPLE translational pancreatic cancer platform

Belinda Lee, Julia Shapiro, Benjamin Thomson, Sumitra Ananda, Lara Lipton, Sue-Anne McLachlan, Rachel Wong, Prasad Cooray, Matthew Burge, Kate Clarke, Sharon Pattison, Mehrdad Nikfarjam, Niall Tebbutt, Marion Harris, Daniel Croagh, David Goldstein, Adnan Nagrial, Rob Zielinski, Amitesh Roy, Cheng Ean Chee, et al.

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY