Julie McAuley

Validation of a single-step, single-tube reverse transcription loop-mediated isothermal amplification assay for rapid detection of SARS-CoV-2 RNA.

Jean YH Lee, Nickala Best, Julie McAuley, Jessica L Porter, Torsten Seemann, Mark B Schultz, Michelle Sait, Nicole Orlando, Karolina Mercoulia, Susan A Ballard, Julian Druce, Thomas Tran, Mike G Catton, Melinda J Pryor, Huanhuan L Cui, Angela Luttick, Sean McDonald, Arran Greenhalgh, Jason C Kwong, Norelle L Sherry, et al.

Journal article  |  2020  |  Journal of Medical Microbiology

Introduction. The SARS-CoV-2 pandemic of 2020 has resulted in unparalleled requirements for RNA extraction kits and enzymes requir..

Passaging of an influenza A(H1N1)pdm09 virus in a difluoro sialic acid inhibitor selects for a novel, but unfit I106M neuraminidase mutant

Jennifer L McKimm-Breschkin, Susan Barrett, Charley McKenzie-Kludas, Julie McAuley, Victor A Streltsov, Stephen G Withers

Journal article  |  2019  |  Antiviral Research

An influenza A(H1N1)pdm09 and an influenza B virus were passaged in 3-fluoro(eq)-4-guanidino difluoro sialic acid (3Feq4Gu DFSA), ..

The Role of the Cell Surface Mucin MUC1 as a Barrier to Infection and Regulator of Inflammation

Poshmaal Dhar, Julie McAuley

Journal article  |  2019  |  Frontiers in Cellular and Infection Microbiology

The family of cell surface (cs-) mucins are constitutively expressed at the cell surface by nearly all epithelial cells, beneath t..

Influenza Virus Neuraminidase Structure and Functions

Julie L McAuley, Brad P Gilbertson, Sanja Trifkovic, Lorena E Brown, Jennifer L McKimm-Breschkin

Journal article  |  2019  |  Frontiers in Microbiology

The role of the NLRP3 inflammasome in regulation of antiviral responses to influenza A virus infection

Soroush T Sarvestani, Julie L McAuley

Journal article  |  2017  |  Antiviral Research

The cell surface mucin MUC1 limits the severity of influenza A virus infection

JL McAuley, L Corcilius, H-X Tan, RJ Payne, MA McGuckin, LE Brown

Journal article  |  2017  |  Mucosal Immunology

Rapid evolution of the PB1-F2 virulence protein expressed by human seasonal H3N2 influenza viruses reduces inflammatory responses to infection

Julie McAuley, Yi-Mo Deng, Brad Gilbertson, Charley Mackenzie-Kludas, Ian Barr, Lorena Brown

Journal article  |  2017  |  Virology Journal

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome

Anita Pinar, Jennifer K Dowling, Natalie J Bitto, Avril AB Robertson, Eicke Latz, Cameron R Stewart, Grant R Drummond, Matthew A Cooper, Julie L McAuley, Michelle D Tate, Ashley Mansell

Journal article  |  2017  |  Journal of Biological Chemistry

Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survival

M Tate, A Pinar, J Dowling, J McAuley, A Robertson, M Cooper, A Mansell

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Michelle D Tate, James DH Ong, Jennifer K Dowling, Julie L McAuley, Avril B Robertson, Eicke Latz, Grant R Drummond, Matthew A Cooper, Paul J Hertzog, Ashley Mansell

Journal article  |  2016  |  Scientific Reports

Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation

Patricia Hoi Yee Lee, Nicola Bird, Charley MacKenzie-Kludas, Ashley Mansell, Katherine Kedzierska, Lorena Brown, Julie McAuley

Journal article  |  2016  |  Immunology & Cell Biology

Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-cell responses

Hyon-Xhi Tan, Brad P Gilbertson, Sinthujan Jegaskanda, Sheilajen Alcantara, Thakshila Amarasena, John Stambas, Julie L McAuley, Stephen J Kent, Robert De Rose

Journal article  |  2016  |  Vaccine

Host immunological factors enhancing mortality of young adults during the 1918 influenza pandemic

Julie L McAuley, Katherine Kedzierska, Lorena E Brown, G Dennis Shanks

Journal article  |  2015  |  Frontiers in Immunology

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

Julie L McAuley, Michelle D Tate, Charley J MacKenzie-Kludas, Anita Pinar, Weiguang Zeng, Andrea Stutz, Eicke Latz, Lorena E Brown, Ashley Mansell

Journal article  |  2013  |  PLOS PATHOGENS

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

Amber M Smith, Frederick R Adler, Ruy M Ribeiro, Ryan N Gutenkunst, Julie L McAuley, Jonathan A McCullers, Alan S Perelson

Journal article  |  2013  |  PLoS Pathogens

Influenza a virus protein PB1-F2 activates the NLRP3 inflammasome to induce inflammation

A Mansell, J McAuley, M Tate, E Latz

Conference Proceedings  |  2012  |  Cytokine

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82

Irina V Alymova, Amanda M Green, Nicholas van de Velde, Julie L McAuley, Kelli L Boyd, Hazem E Ghoneim, Jonathan A McCullers

Journal article  |  2011  |  Journal of Virology

Pro-inflammatory effects of H5N1 and 20th century pandemic influenza virus PB1-F2 proteins are mediated by macrophages

Julie L McAuley, Jonathan A McCullers

Conference Proceedings  |  2011  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Bacterial super-infections: the other side of influenza pathogenesis

Julie L McAuley, Jonathan A McCullers

Conference Proceedings  |  2011  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Influenza Virus Primes Mice for Pneumonia From Staphylococcus aureus

Amy R Iverson, Kelli L Boyd, Julie L McAuley, Lisa R Plano, Mark E Hart, Jonathan A McCullers

Journal article  |  2011  |  The Journal of Infectious Diseases

Effect of 1918 PB1-F2 Expression on Influenza A Virus Infection Kinetics

Amber M Smith, Frederick R Adler, Julie L McAuley, Ryan N Gutenkunst, Ruy M Ribeiro, Jonathan A McCullers, Alan S Perelson

Journal article  |  2011  |  PLoS Computational Biology

Influenza Enhances Susceptibility to Natural Acquisition of and Disease due to Streptococcus pneumoniae in Ferrets

Jonathan A McCullers, Julie L McAuley, Sarah Browall, Amy R Iverson, Kelli L Boyd, Birgitta Henriques Normark

Journal article  |  2010  |  The Journal of Infectious Diseases

PB1-F2 Proteins from H5N1 and 20(th) Century Pandemic Influenza Viruses Cause Immunopathology

Julie L McAuley, Jerry E Chipuk, Kelli L Boyd, Nick Van de Velde, Douglas R Green, Jonathan A McCullers

Journal article  |  2010  |  PLoS Pathogens

The Effects of Influenza A Virus PB1-F2 Protein on Polymerase Activity Are Strain Specific and Do Not Impact Pathogenesis

Julie L McAuley, Kelly Zhang, Jonathan A McCullers

Journal article  |  2010  |  Journal of Virology

Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse

PA Dawson, S Huxley, B Gardiner, T Tran, JL McAuley, S Grimmond, MA McGuckin, D Markovich

Journal article  |  2009  |  Gut

Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia

Julie L McAuley, Felicita Hornung, Kelli L Boyd, Amber M Smith, Raelene McKeon, Jack Bennink, Jonathan W Yewdell, Jonathan A McCullers

Journal article  |  2007  |  Cell Host & Microbe

Muc1 mucin limits both Helicobacter pylori colonization of the murine gastric mucosa and associated gastritis

Michael A Mcguckin, Alison L Every, Caroline D Skene, Sara K Linden, Yok Teng Chionh, Agnieszka Swierczak, Julie Mcauley, Stacey Harbour, Maria Kaparakis, Richard Ferrero, Philip Sutton

Journal article  |  2007  |  Gastroenterology

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

Julie L McAuley, Sara K Linden, Chin Wen Png, Rebecca M King, Helen L Pennington, Sandra J Gendler, Timothy H Florin, Geoff R Hill, Victoria Korolik, Michael A McGuckin

Journal article  |  2007  |  Journal of Clinical Investigation

Bacterial sinusitis and otitis media following influenza virus infection in ferrets

VT Peltola, KL Boyd, JL McAuley, JE Rehg, JA McCullers

Journal article  |  2006  |  Infection and Immunity