Associate Professor Sally Gras is a Reader in the Department of Chemical and Biomolecular Engineering at The University of Melbourne and Director of The ARC Dairy Innovation Hub.
Current Research Activities
- Nano and Biomolecular Engineering
- Nanostructured Materials
- Tailored Biomaterials and Emulsions
- Nano-diagnostics, nano-toxicology, nano-therapeutics
- Fermentation processes and scale-up
Find out more about Sally Gras' experience
Sally Gras' highlights
Sally Gras' selected work
Heat induced denaturation, aggregation and gelation of almond proteins in skim and full fa..
Displaying the 81 most recent projects by Sally Gras.
Dairy Innovation Hub: Transformational Research To Underpin The Future Of The Australian Dairy Manufacturing Industry (Internal Record)
The University of Melbourne, The University of Queensland and Dairy Innovation Australia will join in this Research Hub to address significa..
Internal Research Grant
Displaying the 143 most recent scholarly works by Sally Gras.
Heat induced denaturation, aggregation and gelation of almond proteins in skim and full fat almond milk
Bhanu Devnani, Lydia Ong, Sandra Kentish, Sally Gras
Journal article | 2020 | Food Chemistry
The effect of thermal treatment (45-95 ⁰C for 30 minutes) on the structure of almond milk proteins was assessed, as the unfolding ..
The role of cations in regulating reaction pathways driven by Bacillus circulans β-galactosidase
M Karimi Alavijeh, AS Meyer, S Gras, SE Kentish
Journal article | 2020 | Chemical Engineering Journal
A β-galactosidase (EC 220.127.116.11) from Bacillus circulans (Biolacta FN5) can catalyse transgalactosylation reactions with lactose as..
Formation of Cheddar cheese analogues using canola oil and ultrasonication – a comparison between single and double emulsion systems
Thomas SH Leong, Lydia Ong, Charitha J Gamlath, Sally L Gras, Muthupandian Ashokkumar, Gregory JO Martin
Journal article | 2020 | International Dairy Journal
Cheddar cheese analogues were produced from skim milk in which canola oil was emulsified using ultrasound to form either single (O..
High-Efficiency Biocatalytic Conversion of Thebaine to Codeine
Xu Li, Konrad Krysiak-Baltyn, Luke Richards, Ailsa Jarrold, Geoffrey W Stevens, Tim Bowser, Robert E Speight, Sally L Gras
Journal article | 2020 | ACS Omega
An enzymatic biosynthesis approach is described for codeine, the most widely used medicinal opiate, providing a more environmental..
Tailoring the structure of casein micelles through a multifactorial approach to manipulate rennet coagulation properties
F Lazzaro, A Bouchoux, J Raynes, R Williams, L Ong, E Hanssen, V Lechevalier, S Pezennec, HJ Cho, A Logan, S Gras, F Gaucheron
Journal article | 2020 | Food Hydrocolloids
The properties of casein micelles are known to be affected by modifications to the environment, such as variations in pH or the ad..
The Effect of Salt on the Structure of Individual Fat Globules and the Microstructure of Dry Salted Cheddar Cheese
L Ong, P D’Incecco, L Pellegrino, HTH Nguyen, SE Kentish, SL Gras
Journal article | 2020 | Food Biophysics
Salting is an essential step in the production of Cheddar and other cheese varieties and is a well-studied process but the effect ..
Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture
M Karimi Alavijeh, AS Meyer, S Gras, SE Kentish
Journal article | 2020 | Biochemical Engineering Journal
N-acetyllactosamine (LacNAc) is an important lactose-derived molecule which can act as an effective prebiotic. In this study a pro..
Structural-rheological characteristics of Chaplin E peptide at the air/water interface; a comparison with β-lactoglobulin and β-casein.
Mina Dokouhaki, Emma L Prime, Greg G Qiao, Stefan Kasapis, Li Day, Sally L Gras
Journal article | 2020 | International Journal of Biological Macromolecules
The Chaplin E peptide is a surface-active agent that can adsorb to the air/water interface and form interfacial films that display..
The microstructure and textural properties of Australian cream cheese with differing composition
Phoebe E Macdougall, Lydia Ong, Martin Palmer, Sally L Gras
Journal article | 2019 | International Dairy Journal
Confocal laser scanning microscopy was used to compare the microstructure of six Australian commercial cream cheese products. The ..
Production of metabolites of the anti-cancer drug noscapine using a P450BM3 mutant library.
Luke Richards, Adrian Lutz, David K Chalmers, Ailsa Jarrold, Tim Bowser, Geoffrey W Stevens, Sally L Gras
Journal article | 2019 | Biotechnology Reports
Cytochrome P450 enzymes are a promising tool for the late-stage diversification of lead drug candidates and can provide an alterna..
Exciton-Driven Chemical Sensors Based on Excitation-Dependent Photoluminescent Two-Dimensional SnS
Azmira Jannat, Farjana Haque, Kai Xu, Chunhua Zhou, Bao Yue Zhang, Nitu Syed, Md Mohiuddin, Kibret A Messalea, Xu Li, Sally L Gras, Xiaoming Wen, Zhengdong Fei, Enamul Haque, Sumeet Walia, Torben Daeneke, Ali Zavabeti, Jian Zhen Ou
Journal article | 2019 | ACS Applied Materials & Interfaces
Excitation wavelength-dependent photoluminescence (PL) in two-dimensional (2D) transition-metal chalcogenides enables a strong exc..
The characterisation of Mozzarella cheese microstructure using high resolution synchrotron transmission and ATR-FTIR microspectroscopy
Anita P Pax, Lydia Ong, Jitraporn Vongsvivut, Mark J Tobin, Sandra E Kentish, Sally L Gras
Journal article | 2019 | Food Chemistry
Synchrotron Fourier transform infrared (S-FTIR) microspectroscopy allows the label-free examination of material microstructure but..
Impact of processing conditions on microstructure, texture and chemical properties of model cheese from sheep milk
A Aldalur, L Ong, MÁ Bustamante, SL Gras, LJR Barron
Journal article | 2019 | Food and Bioproducts Processing
Cutting and cooking settings have a strong effect on curd particle features, whey syneresis and cheese properties. In the present ..
Comparison of physical characteristics and dewatering behaviour between granular and floccular sludges generated from the same sewage source
Konrad Krysiak-Baltyn, Raul Cavalida, Ben Thwaites, Petra J Reeve, Peter J Scales, Ben Van den Akker, Lydia Ong, Gregory JO Martin, Anthony D Stickland, Sally L Gras
Journal article | 2019 | Journal of Water Process Engineering
Aerobic granular sludge can improve the efficacy of wastewater treatment in existing sequencing batch reactors (SBRs) compared to ..
A pilot scale study on the concentration of milk and whey by forward osmosis.
George Chen, A Artemi, J Lee, S Gras, Sandra Kentish
Journal article | 2019 | Separation and Purification Technology
The concentration of skim milk and whey was investigated at a pilot scale using forward osmosis membranes with an installed membra..
A fluorescence in situ staining method for investigating spores and vegetative cells of Clostridia by confocal laser scanning microscopy and structured illuminated microscopy
P D'Incecco, L Ong, S Gras, L Pellegrino
Journal article | 2018 | Micron
Non-pathogenic spore-forming Clostridia are of increasing interest due to their application in biogas production and their capabil..
Small scale production of cream cheese: A comparison of batch centrifugation and cloth bag methods
Lydia Ong, Sandra E Kentish, Sally L Gras
Journal article | 2018 | International Dairy Journal
Cream cheese production is well established at large scale but an effective small scale process could facilitate higher throughput..
Effect of temperature on the microstructure of fat globules and the immunoglobulin-mediated interactions between fat and bacteria in natural raw milk creaming
P D'Incecco, L Ong, L Pellegrino, F Faoro, A Barbiroli, S Gras
Journal article | 2018 | Journal of Dairy Science
Natural creaming of raw milk is the first step in production of Grana Padano and Parmigiano Reggiano Protected Denomination of Ori..
Recent advances in macro ATR-FTIR microspectroscopic technique for high resolution surface characterisation at Australian Synchrotron IR Beamline
J Vongsvivut, VK Truong, N Hameed, DA Beattie, M Krasowska, S Gras, GS Watson, JA Watson, D Perez-Guaita, P Heraud, BR Wood, J Morikawa, S Juodkazis, EP Ivanova, MJ Tobin
Conference Proceedings | 2018 | High-Brightness Sources and Light-driven Interactions
Microstructure and physicochemical properties reveal differences between high moisture buffalo and bovine Mozzarella cheeses
Hanh TH Nguyen, Lydia Ong, Christelle Lopez, Sandra E Kentish, Sally L Gras
Journal article | 2017 | Food Research International
Mozzarella cheese is a classical dairy product but most research to date has focused on low moisture products. In this study, the ..
Biofilm communities and biodegradation within permeable reactive barriers at fuel spill sites in Antarctica
Benjamin L Freidman, Lachlan BM Speirs, Jack Churchill, Sally L Gras, Joe Tucci, Ian Snape, Geoffrey W Stevens, Kathryn A Mumford
Journal article | 2017 | International Biodeterioration & Biodegradation
Effect of elevated temperature on the microstructure of full fat Cheddar cheese during ripening
Kevany Soodam, Lydia Ong, Ian B Powell, Sandra E Kentish, Sally L Gras
Journal article | 2017 | Food Structure
Elevated temperatures have been widely studied as a route to accelerate cheese ripening and decrease energy and storage requiremen..
A proteomic characterization shows differences in the milk fat globule membrane of buffalo and bovine milk
Hanh TH Nguyen, Lydia Ong, Ashfaqul Hoque, Sandra E Kentish, Nicholas Williamson, Ching-Seng Ang, Sally L Gras
Journal article | 2017 | Food Bioscience
The proteins of the milk fat globule membrane (MFGM) have a number of functions, such as the regulation of milk fat secretion and ..
Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis
Yasmin M Ramdzan, Mikhail M Trubetskov, Angelique R Ormsby, Estella A Newcombe, Xiaojing Sui, Mark J Tobin, Marie N Bongiovanni, Sally L Gras, Grant Dewson, Jason ML Miller, Steven Finkbeiner, Nagaraj S Moily, Jonathan Niclis, Clare L Parish, Anthony W Purcell, Michael J Baker, Jacqueline A Wilce, Saboora Waris, Diana Stojanovski, Till Bocking, et al.
Journal article | 2017 | Cell reports
Direct demonstration of lipid phosphorylation in the lipid bilayer of the biomimetic bicontinuous cubic phase using the confined enzyme lipid A phosphoethanolamine transferase
Leonie van't Hag, Anandhi Anandan, Shane A Seabrook, Sally L Gras, Calum J Drummond, Alice Vrielink, Charlotte E Conn
Journal article | 2017 | Soft Matter
Effect of Lipid-Based Nanostructure on Protein Encapsulation within the Membrane Bilayer Mimetic Lipidic Cubic Phase Using Transmembrane and Lipo-proteins from the Beta-Barrel Assembly Machinery
Leonie van't Hag, Hsin-Hui Shen, Tsung-Wu Lin, Sally L Gras, Calum J Drummond, Charlotte E Conn
Journal article | 2016 | Langmuir
The dynamics of the biological membrane surrounding the buffalo milk fat globule investigated as a function of temperature
Hanh TH Nguyen, Marie-Noelle Madec, Lydia Ong, Sandra E Kentish, Sally L Gras, Christelle Lopez
Journal article | 2016 | Food Chemistry
The biological membrane surrounding fat globules in milk (the MFGM) is poorly understood, despite its importance in digestion and ..
Exploring the in meso crystallization mechanism by characterizing the lipid mesophase microenvironment during the growth of single transmembrane alpha-helical peptide crystals
Leonie van 't Hag, Konstantin Knoblich, Shane A Seabrook, Nigel M Kirby, Stephen T Mudie, Deborah Lau, Xu Li, Sally L Gras, Xavier Mulet, Matthew E Call, Melissa J Call, Calum J Drummond, Charlotte E Conn
Journal article | 2016 | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Using SANS with Contrast-Matched Lipid Bicontinuous Cubic Phases To Determine the Location of Encapsulated Peptides, Proteins, and Other Biomolecules
Leonie van 't Hag, Liliana de Campo, Christopher J Garvey, George C Feast, Anna E Leung, Nageshwar Rao Yepuri, Robert Knott, Tamar L Greaves, Tran Nhiem, Sally L Gras, Calum J Drummond, Charlotte E Conn
Journal article | 2016 | The Journal of Physical Chemistry Letters
How Peptide Molecular Structure and Charge Influence the Nanostructure of Lipid Bicontinuous Cubic Mesophases: Model Synthetic WALP Peptides Provide Insights
Leonie van 't Hag, Xu Li, Thomas G Meikle, Soren V Hoffmann, Nykola C Jones, Jan Skov Pedersen, Adrian M Hawley, Sally L Gras, Charlotte E Conn, Calum J Drummond
Journal article | 2016 | Langmuir
The addition of calcium chloride in combination with a lower draining pH to change the microstructure and improve fat retention in Cheddar cheese
Lydia Ong, Kevany Soodam, Sandra E Kentish, Ian B Powell, Sally L Gras
Journal article | 2015 | International Dairy Journal
Calcium chloride addition and the whey draining pH are known to impact on cheese making. The effect of 100 or 300 mg kg−1 calcium ..
Buffalo milk fat globules and their biological membrane: in situ structural investigations
Hanh TH Nguyen, Lydia Ong, Eric Beaucher, Marie-Noelle Madec, Sandra E Kentish, Sally L Gras, Christelle Lopez
Journal article | 2015 | Food Research International
Milk fat globules and their surrounding biological membrane (the MFGM) are not well understood despite the importance of these mil..
The Effect of Fermentation Temperature on the Microstructure, Physicochemical and Rheological Properties of Probiotic Buffalo Yoghurt
Hanh TH Nguyen, Lydia Ong, Sandra E Kentish, Sally L Gras
Journal article | 2014 | Food and Bioprocess Technology
The properties of buffalo and bovine milk differ and the procedures developed to make bovine yoghurt may require optimisation for ..
The Microstructure and Physicochemical Properties of Probiotic Buffalo Yoghurt During Fermentation and Storage: a Comparison with Bovine Yoghurt
Thi Hong Nguyen Hanh, Lydia Ong, Christophe Lefevre, Sandra Elizabeth Kentish, Sally Louise Gras
Journal article | 2014 | Food and Bioprocess Technology
The physicochemical and rheological properties of yoghurt made from unstandardised unhomogenised buffalo milk were investigated du..
A radish seed antifungal peptide with a high amyloid fibril-forming propensity
Megan Garvey, Sarah Meehan, Sally L Gras, Horst J Schirra, David J Craik, Nicole L Van der Weerden, Marilyn A Anderson, Juliet A Gerrard, John A Carver
Journal article | 2013 | Biochimica et Biophysica Acta-Proteins and Proteomics
Microstructure and Composition of Full Fat Cheddar Cheese Made with Ultrafiltered Milk Retentate.
Lydia Ong, Raymond R Dagastine, Sandra E Kentish, Sally L Gras
Journal article | 2013 | Foods
Milk protein is often standardised prior to cheese-making using low concentration factor ultrafiltration retentate (LCUFR) but the..
Self-assembling nanomaterials: monitoring the formation of amyloid fibrils, with a focus on small-angle X-ray scattering.
Elizabeth B Sawyer, Sally L Gras
Journal article | 2013 | Methods in Molecular Biology
Amyloid fibrils are attractive targets for applications in biotechnology. These thin, nanoscale protein fibers are highly ordered ..
Polymorphism and higher order structures of protein nanofibers from crude mixtures of fish lens crystallins: Toward useful materials
Jackie Healy, Kang Wong, Elizabeth B Sawyer, Clement Roux, Laura Domigan, Sally L Gras, Margaret Sunde, Nigel G Larsen, Juliet Gerrard, Madhusudan Vasudevamurthy
Journal article | 2012 | Biopolymers
Metastability of Native Proteins and the Phenomenon of Amyloid Formation
Andrew J Baldwin, Tuomas PJ Knowles, Gian Gaetano Tartaglia, Anthony W Fitzpatrick, Glyn L Devlin, Sarah Lucy Shammas, Christopher A Waudby, Maria F Mossuto, Sarah Meehan, Sally L Gras, John Christodoulou, Spencer J Anthony-Cahill, Paul D Barker, Michele Vendruscolo, Christopher M Dobson
Journal article | 2011 | Journal of the American Chemical Society
Feasibility study of enzyme immobilization on polymeric membrane: A case study with enzymatically galacto-oligosaccharides production from lactose
Dwaipayan Sen, Ankur Sarkar, Aaron Gosling, Sally L Gras, Geoff W Stevens, Sandra E Kentish, PK Bhattacharya, Andrew R Barber, Chiranjib Bhattacharjee
Journal article | 2011 | Journal of Membrane Science
Facile Pretreatment of Bacilius circulans beta-Galactosidase Increases the Yield of Galactosyl Oligosaccharides in Milk and Lactose Reaction Systems
Aaron Gosling, Johan Alftren, Geoff W Stevens, Andrew R Barber, Sandra E Kentish, Sally L Gras
Journal article | 2009 | Journal of Agricultural and Food Chemistry
Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of alpha-Synuclein in a pH-Dependent Manner
Chi LL Pham, Su Ling Leong, Feda E Ali, Vijaya B Kenche, Andrew F Hill, Sally L Gras, Kevin J Barnham, Roberto Cappai
Journal article | 2009 | Journal of Molecular Biology
The component polypeptide chains of bovine insulin nucleate or inhibit aggregation of the parent protein in a conformation-dependent manner
Glyn L Devlin, Tuomas PJ Knowles, Adam Squires, Margaret G McCammon, Sally L Gras, Melanie R Nilsson, Carol V Robinson, Christopher M Dobson, Cait E MacPhee
Journal article | 2006 | Journal of Molecular Biology
Displaying the 2 most recent news articles by Sally Gras.
Honours, Awards and Fellowships
Certificate of Excellence for Most Engaged Research Group
Victoria Fellowship - Science Technology and Innovation - Industrial and research centres in Ireland, the UK and Europe to take a new look at cheese
Funding travel to Joint Research Unit for the Science and Technology of Milk and Eggs (INRA) Rennes (Brittany)
Young Scientists Exchange Scheme to China
Attend Teaching Conference Virginia USA
Young Investigator Commendation (oral presentation)
Selby Research Award
Australian French Association for Science and Technology
Australasian Society for Biomaterials
Australian Research Council Nanotechnology Network
Institute Of Chemical Engineers
Doctor of Philosophy (Biophysics and Nanotechnology)
University of Cambridge
Bachelor of Engineering (Chemical Engineering) (Honours)
University of Melbourne
Bachelor of Science (Biochemistry & Molecular Biology) (Honours)
University of Melbourne