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Prof

Ingrid Winship

Chair In Adult Clinical Genetics
Medicine - Royal Melbourne Hospital
Familial cancer
Genodermatoses
Heritable diseases
science & technology
life sciences & biomedicine
humans
female
male
adult
Ingrid Winship's Profile Picture
Prof

Ingrid Winship

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Clinical genetics
Ingrid Winship's Profile Picture
Prof

Ingrid Winship

 
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Ingrid's  Short Profile
 

Ingrid Winship is a clinician scientist and is the Inaugural Chair of Adult Clinical Genetics at the University of Melbourne and The Royal Melbourne Hospital. Her career has combined clinical practice, biomedical research and the translation of research into practice and policy.

While she works across many domains within clinical genetics, her research interests have been focused on colorectal cancer, and in particular the potential for cancer prevention. She has used the knowledge generated by her and other’s research to optimise and implement state of the art clinical genetic services in adult medicine, with a focus on familial cancer and cancer prevention. She is an expert in heritable skin disorders. As Melbourne Health’s Executive Director of Research (2006-2018) she facilitated the embedding of research into clinical practice in this large academic teaching hospital and established the Clinical Trials Centre on the city campus. She is a practicing clinician, providing academic and clinical leadership in the inherited cancer clinics. She served on a number of high level committees within Australia, and internationally; she is currently a Director of the Boards of the Australian Genome Research Facility and Global Variome. She is Chair of the Australian Health Ethics Committee and a member of the NHMRC Council. In June 2020, Professor Winship was appointed Officer of the Order of Australia for "distinguished service to medicine, particularly to clinical genetics and research, to cancer prevention, and as a role model and mentor."

Projects

Displaying the 10 most recent projects by Ingrid Winship.

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SCRIPT: AN RCT OF GENOMIC-BASED STRATIFIED COLORECTAL CANCER SCREENING IN PRIMARY CARE.

2020 - 2023
Active
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WHY DOES COLONOSCOPY FAIL TO PREVENT COLON CANCER IN PEOPLE WITH LYNCH SYNDROME?

2020 - 2022
Active
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HERITABLE METHYLATION MARKS ASSOCIATED WITH COLORECTAL CANCER RISK

2019 - 2021
Active
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A PATIENT-CENTRIC MEASURE-MODEL-MANUFACTURE-MANAGE (4M) PLATFORM FOR PERSONALISED IMPLANT INNOVATION

2018 - 2020
Completed
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TAKING BREAST CANCER RISK PREDICTION TO THE NEXT LEVEL AND MAKING IT ACCESSIBLE.

Women vary enormously in their risk of breast cancer, but screening and prevention programs in Australia and across the world have largely i..

2018 - 2021
Active
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TAKING BREAST CANCER RISK PREDICTION TO THE NEXT LEVEL AND MAKING IT ACCESSIBLE.

Women vary enormously in their risk of breast cancer, but screening and prevention programs in Australia and across the world have largely i..

2018 - 2021
Active
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CLINICAL UTILITY AND COST-EFFECTIVENMESS OF GENOME SEQUENCING FOR REFRACTORY EPILEPSY IN CHILDREN AND ADULTS: A MULTICENTRE RANDOMISED CONTROLLED TRIAL

A large number of genomic variants have been found to underpin common types of epilepsy and to predict adverse drug reactions. However, the ..

2018 - 2021
Active
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THE CRISP TRIAL: AN RCT OF RISK ASSESSMENT AND DECISION SUPPORT TO IMPLEMENT RISK-STRATIFIED COLORECTAL CANCER SCREENING IN PRIMARY CARE.

There is a mismatch between people’s use of bowel cancer screening tests through faecal occult blood testing or colonoscopy and their indivi..

2017 - 2020
Active
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MUIR TORRE SYNDROME: THE ROLE OF IHC AND GENOTYPING IN SEBACEOUS NEOPLASIA TO FACILITATE PREVENTION STRATEGIES IN COLORECTAL AND ENDOMETRIAL CANCER

Sebaceous neoplasia (SN), may be an early warning sign for Lynch syndrome (LS), an inherited cancer predisposition caused by mutations in a ..

2017 - 2019
Completed
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EXPANDING DIAGNOSTIC APPROACHES FOR LYNCH SYNDROME

Currently, there are ~1,000 families who have attended Family Cancer Clinics across Australia who have the hallmarks of having Lynch syndrom..

2017 - 2019
Completed

22

Projects

Project Types

22

Research Grant

Scholarly Works

Displaying the 10 most recent scholarly works by Ingrid Winship.

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The Impact of a Comprehensive Risk Prediction Model for Colorectal Cancer on a Population Screening Program

Sibel Saya, Jon D Emery, James G Dowty, Jennifer G McIntosh, Ingrid M Winship, Mark A Jenkins

Journal article  |  2020  |  JNCI Cancer Spectrum

Abstract Background In many countries, population colorectal cancer (CRC) scre..

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Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia.

Marie E Faughnan, Johannes J Mager, Steven W Hetts, Valerie A Palda, Kelly Lang-Robertson, Elisabetta Buscarini, Erik Deslandres, Raj S Kasthuri, Andrea Lausman, David Poetker, Felix Ratjen, Mark S Chesnutt, Marianne Clancy, Kevin J Whitehead, Hanny Al-Samkari, Murali Chakinala, Miles Conrad, Daniel Cortes, Claudia Crocione, Jama Darling, et al.

Journal article  |  2020  |  Annals of Internal Medicine

DESCRIPTION: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with an estimated prevalence of 1 in 500..

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Is CHEK2 a moderate-risk breast cancer gene or the younger sister of Li-Fraumeni?

Dilanka L De Silva, Ingrid Winship

Journal article  |  2020  |  BMJ Case Reports

The CHEK2 gene is mostly considered as a moderate breast cancer gene with the result that many clinicians have a narrow focus. We ..

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More than meets the eye: Palmoplantar keratoderma and arrhythmogenic right ventricular cardiomyopathy in a patient with loss of the DSP gene.

Jessica Victoria Yao, Ingrid Winship

Journal article  |  2020  |  JAAD Case Reports

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A Genomic Test for Colorectal Cancer Risk: Is This Acceptable and Feasible in Primary Care?

Sibel Saya, Jennifer G McIntosh, Ingrid M Winship, Mark Clendenning, Shakira Milton, Jasmeen Oberoi, James G Dowty, Daniel D Buchanan, Mark A Jenkins, Jon D Emery

Journal article  |  2020  |  Public Health Genomics

INTRODUCTION: Genomic tests can predict risk and tailor screening recommendations for colorectal cancer (CRC). Primary care could ..

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Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Mev Dominguez-Valentin, Julian R Sampson, Toni T Seppälä, Sanne W Ten Broeke, John-Paul Plazzer, Sigve Nakken, Christoph Engel, Stefan Aretz, Mark A Jenkins, Lone Sunde, Inge Bernstein, Gabriel Capella, Francesc Balaguer, Huw Thomas, D Gareth Evans, John Burn, Marc Greenblatt, Eivind Hovig, Wouter H de Vos Tot Nederveen Cappel, Rolf H Sijmons, et al.

Artefact  |  2020  |  Genetics in Medicine

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database

Mev Dominguez-Valentin, Toni T Seppala, Christoph Engel, Stefan Aretz, Finlay Macrae, Ingrid Winship, Gabriel Capella, Huw Thomas, Eivind Hovig, Maartje Nielsen, Rolf H Sijmons, Lucio Bertario, Bernardo Bonanni, Maria Grazia Tibiletti, Giulia Martina Cavestro, Miriam Mints, Nathan Gluck, Lior Katz, Karl Heinimann, Carlos A Vaccaro, et al.

Journal article  |  2020  |  Journal of Clinical Medicine

PURPOSE: To survey risk-reducing hysterectomy and bilateral salpingo-oophorectomy (BSO) practice and advice regarding hormone repl..

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Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

Paul Lacaze, Robert Sebra, Moeen Riaz, Jane Tiller, Jerico Revote, James Phung, Emily J Parker, Suzanne G Orchard, Jessica E Lockery, Rory Wolfe, Maya Strahl, Ying C Wang, Rong Chen, Daniel Sisco, Todd Arnold, Bryony A Thompson, Daniel D Buchanan, Finlay A Macrae, Paul A James, Walter P Abhayaratna, et al.

Journal article  |  2020  |  Genetics in Medicine

PURPOSE: To measure the prevalence of medically actionable pathogenic variants (PVs) among a population of healthy elderly individ..

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Phenotypic discordance between siblings with junctional epidermolysis bullosa-pyloric atresia

KP Verma, SJ Robertson, IM Winship

Journal article  |  2020  |  Clinical and Experimental Dermatology

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Mismatch repair gene pathogenic germline variants in a population-based cohort of breast cancer

Tu Nguyen-Dumont, Jason A Steen, Ingrid Winship, Daniel J Park, Bernard J Pope, Fleur Hammet, Maryam Mahmoodi, Helen Tsimiklis, Derrick Theys, Mark Clendenning, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2020  |  Familial Cancer

The advent of gene panel testing is challenging the previous practice of using clinically defined cancer family syndromes to infor..

268

Scholarly Works

Keyword Analysis

Clinical Health (organs, Diseases and Abnormal Conditions)
Oncology and Carcinogenesis
Clinical Sciences
Public Health and Health Services
Clinical (organs, Diseases and Abnormal Conditions)
Specific Population Health (excl. Indigenous Health)
Genetics
Health and Support Services
Expanding Knowledge
Public Health (excl. Specific Population Health)

News

Displaying the 1 most recent news article by Ingrid Winship.

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Precision medicine offers the hope of cures made just for you

Ingrid Winship, Timothy Smith

January 29, 2015

1

News Articles

Honours, Awards and Fellowships

2020

Officer of the Order of Australia

1998

Clinical Geneticist

Human Genetics Society of Australasia
2017

FAICD - Fellow of the Australian Institute of Company Directors

2008

FACD - Fellow of the Australasian College of Dermatologists

2002

FRACP - Fellow of the Royal Australasian College of Physicians

5

Awards

Credentials

Positions

Positions

Chair In Adult Clinical Genetics

Medicine - Royal Melbourne Hospital

Education

Education

Doctor of Medicine

University of Cape Town

MBChB

University of Cape Town

Links

Links