My principal research interests lie in understanding the evolution of drug resistance in bacteria as well as use of metagenomics as a tool for understanding microbiome dynamics of the built environment. I am currently employed as a Postdoctoral Research Fellow in Bioinformatics at the Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne.
We use computational approaches to detect, characterise and resolve outbreaks for public and clinical health surveillance. In previous roles, I have worked as a postdoctoral fellow in genomics and bioinformatics (Holt Lab UoM; Division of Infection and Immunity WEHI) and travelled on biological surveys as a marine and freshwater biologist to remote areas including Antarctica, Indonesia, Vietnam and New Guinea. An up-to-date list of my publications can be found at https://goo.gl/py55BT
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Co-Evolution Of Heavy Metal And Antibiotic Resistance In Hot-Spring Microbes
Internal Research Grant
The changing landscape of vancomycin-resistant Enterococcus faecium in Australia: a popula..
Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-..
Genomic exploration of sequential clinical isolates reveals a distinctive molecular signat..
Displaying the 2 most recent projects by Mark Schultz.
Displaying the 48 most recent scholarly works by Mark Schultz.
Isolation and rapid sharing of the 2019 novel coronavirus (SAR-CoV-2) from the first patient diagnosed with COVID-19 in Australia
Leon Caly, Julian Druce, Jason Roberts, Katherine Bond, Thomas Tran, Renata Kostecki, Yano Yoga, William Naughton, George Taiaroa, Torsten Seemann, Mark B Schultz, Benjamin P Howden, Tony M Korman, Sharon R Lewin, Deborah A Williamson, Mike G Catton
Journal article | 2020 | Medical Journal of Australia
OBJECTIVES: To describe the first isolation and sequencing of SARS-CoV-2 in Australia and rapid sharing of the isolate. SETTING: S..
Genomic investigation of Staphylococcus aureus recovered from Gambian women and newborns following an oral dose of intra-partum azithromycin
Abdoulie Bojang, Sarah L Baines, Liam Donovan, Romain Guerillot, Kerrie Stevens, Charlie Higgs, Christian Bottomley, Ousman Secka, Mark B Schultz, Anders Goncalves da Silva, Torsten Seemann, Timothy P Stinear, Anna Roca, Benjamin P Howden
Journal article | 2019 | Journal of Antimicrobial Chemotherapy
BACKGROUND: Oral azithromycin given during labour reduces carriage of bacteria responsible for neonatal sepsis, including Staphylo..
Genomics for Molecular Epidemiology and Detecting Transmission of Carbapenemase-Producing Enterobacterales in Victoria, Australia, 2012 to 2016
Norelle L Sherry, Courtney R Lane, Jason C Kwong, Mark Schultz, Michelle Sait, Kerrie Stevens, Susan Ballard, Anders Goncalves da Silva, Torsten Seemann, Claire L Gorrie, Timothy P Stinear, Deborah A Williamson, Judith Brett, Annaliese van Diemen, Marion Easton, Benjamin P Howden
Journal article | 2019 | Journal of Clinical Microbiology
Background Carbapenemase-producing Enterobacterales (CPE) are being increasingly reported in Australia, and i..
Reconstruction of the Genomes of Drug-Resistant Pathogens for Outbreak Investigation through Metagenomic Sequencing
Andre Mu, Jason C Kwong, Nicole S Isles, Anders Goncalves da Silva, Mark B Schultz, Susan A Ballard, Courtney R Lane, Glen P Carter, Deborah A Williamson, Torsten Seemann, Timothy P Stinear, Benjamin P Howden
Journal article | 2019 | mSphere
The changing landscape of vancomycin-resistant Enterococcus faecium in Australia: a population-level genomic study
Robyn S Lee, Anders Goncalves da Silva, Sarah L Baines, Janet Strachan, Susan Ballard, Glen P Carter, Jason C Kwong, Mark B Schultz, Dieter M Bulach, Torsten Seemann, Timothy P Stinear, Benjamin P Howden
Journal article | 2018 | Journal of Antimicrobial Chemotherapy
Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)
Romain Guerillot, Lucy Li, Sarah Baines, Brian Howden, Mark B Schultz, Torsten Seemann, Ian Monk, Sacha J Pidot, Wei Gao, Stefano Giulieri, Anders Goncalves da Silva, Anthony D'Agata, Takehiro Tomita, Anton Y Peleg, Timothy P Stinear, Benjamin P Howden
Journal article | 2018 | Genome Medicine
Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia
Stefano G Giulieri, Sarah L Baines, Romain Guerillot, Torsten Seemann, Anders Goncalves da Silva, Mark Schultz, Ruth C Massey, Natasha E Holmes, Timothy P Stinear, Benjamin P Howden
Journal article | 2018 | Genome Medicine
The changing landscape of VREfm in Victoria, Australia: a State-wide genomic snapshot
Robyn Lee, Anders Gonçalves da Silva, Sarah Baines, Janet Strachan, Susan Ballard, Glen Carter, Jason Kwong, Mark Schultz, Dieter Bulach, Torsten Seemann, Timothy Stinear, Benjamin Howden
Journal article | 2018
Abstract Vancomycin-resistant Enterococcus faecium (VREfm) represent a major source of nosocomial infection worldwide. In Australi..
Genomic Exploration of Within-Host Microevolution Reveals a Distinctive Molecular Signature of Persistent Staphylococcus aureus Bacteraemia
Stefano Giulieri, Sarah Baines, Romain Guerillot, Torsten Semann, Anders Goncalves da Silva, Mark Schultz, Ruth Massey, Natasha Holmes, Timothy Stinear, Benjamin Howden
Journal article | 2018 | Genome Medicine
Background: Large-scale genomic studies of within-host evolution during Staphylococcus aureus bacteraemia (SAB) are needed to unde..
Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus
Glen P Carter, Mark B Schultz, Sarah L Baines, Anders Goncalves da Silva, Helen Heffernan, Audrey Tiong, Peter H Pham, Ian R Monk, Timothy P Stinear, Benjamin P Howden, Deborah A Williamson
Journal article | 2018 | Antimicrobial Agents and Chemotherapy
Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: evidence from a complex multi-institutional KPC outbreak
Jason C Kwong, Courtney R Lane, Finn Romanes, Anders Goncalves da Silva, Marion Easton, Katie Cronin, Mary Jo Waters, Takehiro Tomita, Kerrie Stevens, Mark B Schultz, Sarah L Baines, Norelle L Sherry, Glen P Carter, Andre Mu, Michelle Sait, Susan A Ballard, Torsten Seemann, Timothy P Stinear, Benjamin P Howden
Journal article | 2018 | PeerJ
A Supervised Statistical Learning Approach for Accurate Legionella pneumophila Source Attribution during Outbreaks
Andrew H Buultjens, Kyra YL Chua, Sarah L Baines, Jason Kwong, Wei Gao, Zoe Cutcher, Stuart Adcock, Susan Ballard, Mark B Schultz, Takehiro Tomita, Nela Subasinghe, Glen P Carter, Sacha J Pidot, Lucinda Franklin, Torsten Seemann, Anders Goncalves Da Silva, Benjamin P Howden, Timothy P Stinear
Journal article | 2017 | Applied and Environmental Microbiology
Real-time genomic and epidemiological investigation of a multi-institution outbreak of KPC-producing Enterobacteriaceae: a translational study
JC Kwong, C Lane, F Romanes, A Gonçalves da Silva, M Easton, K Cronin, MJ Waters, T Tomita, K Stevens, MB Schultz, SL Baines, NL Sherry, G Carter, A Mu, M Sait, SA Ballard, T Seemann, TP Stinear, BP Howden
Journal article | 2017
ABSTRACT Background Until recently, KPC-producing Enterobacteriaceae were rarely identified in Australia. Following an increase in..
Target-Specific Assay for Rapid and Quantitative Detection of Mycobacterium chimaera DNA
Enrique Zozaya-Valdes, Jessica L Porter, John Coventry, Janet AM Fyfe, Glen P Carter, Anders Goncalves da Silva, Mark B Schultz, Torsten Seemann, Paul DR Johnson, Andrew J Stewardson, Ivan Bastian, Sally A Roberts, Benjamin P Howden, Deborah A Williamson, Timothy P Stinear
Journal article | 2017 | Journal of Clinical Microbiology
A supervised statistical learning approach for accurate Legionella pneumophila source attribution during outbreaks
Andrew Buultjens, Kyra Chua, Sarah Baines, Jason Kwong, Wei Gao, Zoe Cutcher, Stuart Adcock, Susan Ballard, Mark Schultz, Takehiro Tomita, Nela Subasinghe, Glen Carter, Sacha Pidot, Lucinda Franklin, Torsten Seemann, Anders Gonçalves Da Silva, Benjamin Howden, Timothy Stinear
Journal article | 2017
Abstract Public health agencies are increasingly relying on genomics during Legionnaires’ disease investigations. However, the cau..
Donor-derived Mycoplasma hominis and an apparent cluster of M. hominis cases in solid organ transplant recipients
OC Smibert, HL Wilson, A Sohail, S Narayanasamy, MB Schultz, SA Ballard, JC Kwong, J de Boer, O Morrissey, AY Peleg, undefined others
Journal article | 2017 | Clinical Infectious Diseases
Genomic Insights into a Sustained National Outbreak of Yersinia pseudotuberculosis
Deborah A Williamson, Sarah L Baines, Glen P Carter, Anders Goncalves da silva, Xiaoyun Ren, Jill Sherwood, Muriel Dufour, Mark B Schultz, Nigel P French, Torsten Seemann, Timothy P Stinear, Benjamin P Howden
Journal article | 2016 | Genome Biology and Evolution
First comprehensive multi-tissue transcriptome of Cherax quadricarinatus (Decapoda: Parastacidae) reveals unexpected diversity of endogenous cellulase
Mun Hua Tan, Han Ming Gan, Huan You Gan, Yin Peng Lee, Larry J Croft, Mark B Schultz, Adam D Miller, Christopher M Austin
Journal article | 2016 | Organisms Diversity & Evolution
Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward
Mark B Schultz, Pham Thanh Duy, Tran Do Hoan Nhu, Ryan R Wick, Danielle J Ingle, Jane Hawkey, David J Edwards, Johanna J Kenyon, Phu Huong Lan Nguyen, James I Campbell, Guy Thwaites, Thi Khanh Nhu Nguyen, Ruth M Hall, Alexandre Fournier-Level, Stephen Baker, Kathryn E Holt
Journal article | 2016 | Microbial Genomics
Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
Kathryn E Holt, Heiman Wertheim, Ruth N Zadoks, Stephen Baker, Chris A Whitehouse, David Dance, Adam Jenney, Thomas R Connor, Li Yang Hsu, Juliette Severin, Sylvain Brisse, Hanwei Cao, Jonathan Wilksch, Claire Gorrie, Mark B Schultz, David J Edwards, Van Nguyen Kinh, Vu Nguyen Trung, Tuyet Dao Trinh, Martijn Mensinke, et al.
Journal article | 2015 | Proceedings of the National Academy of Sciences
MitoPhAST, a new automated mitogenomic phylogeny tool in the post-genomic era with a case study of 89 decapod mitogenomes including eight new freshwater crayfish mitogenomes
Mun Hua Tan, Han Ming Gan, Mark B Schultz, Christopher M Austin
Journal article | 2015 | Molecular Phylogenetics and Evolution
Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant Staphylococcus aureus
Sarah L Baines, Kathryn E Holt, Mark B Schultz, Torsten Seemann, Brian O Howden, Slade O Jensen, Sebastiaan J van Hal, Geoffrey W Coombs, Neville Firth, David R Powell, Timothy P Stinear, Benjamin P Howden
Journal article | 2015 | mBio
Multiple drivers of decline in the global status of freshwater crayfish (Decapoda: Astacidea)
Nadia I Richman, Monika Boehm, Susan B Adams, Fernando Alvarez, Elizabeth A Bergey, John JS Bunn, Quinton Burnham, Jay Cordeiro, Jason Coughran, Keith A Crandall, Kathryn L Dawkins, Robert J DiStefano, Niall E Doran, Lennart Edsman, Arnold G Eversole, Leopold Fuereder, James M Furse, Francesca Gherardi, Premek Hamr, David M Holdich, et al.
Journal article | 2015 | Philosophical Transactions of the Royal Society B: Biological Sciences
Mitochondrial DNA analyses reveal widespread tardigrade diversity in Antarctica
Alejandro Velasco-Castrillon, Sandra J McInnes, Mark B Schultz, Maria Arroniz-Crespo, Cyrille A D'Haese, John AE Gibson, Byron J Adams, Timothy J Page, Andrew D Austin, Steven JB Cooper, Mark I Stevens
Journal article | 2015 | INVERTEBRATE SYSTEMATICS
Phylogeography of var gene repertoires reveals fine-scale geospatial clustering of Plasmodium falciparum populations in a highly endemic area
Sofonias K Tessema, Stephanie L Monk, Mark B Schultz, Livingstone Tavul, John C Reeder, Peter M Siba, Ivo Mueller, Alyssa E Barry
Journal article | 2015 | Molecular Ecology
Nuclear and Mitochondrial Patterns of Population Structure in North Pacific False Killer Whales (Pseudorca crassidens)
Karen K Martien, Susan J Chivers, Robin W Baird, Frederick I Archer, Antoinette M Gorgone, Brittany L Hancock-Hanser, David Mattila, Daniel J McSweeney, Erin M Oleson, Carol Palmer, Victoria L Pease, Kelly M Robertson, Gregory S Schorr, Mark B Schultz, Daniel L Webster, Barbara L Taylor
Journal article | 2014 | Journal of Heredity
Phylogenetic analyses reveal extensive cryptic speciation and host specialization in an economically important mite taxon
Adam D Miller, Anna Skoracka, Denise Navia, Renata Santos de Mendonca, Wiktoria Szydlo, Mark B Schultz, C Michael Smith, Graciela Truol, Ary A Hoffmann
Journal article | 2013 | Molecular Phylogenetics and Evolution
Evolution underground: A molecular phylogenetic investigation of Australian burrowing freshwater crayfish (Decapoda: Parastacidae) with particular focus on Engaeus Erichson
Mark B Schultz, Sarah A Smith, Pierre Horwitz, Alastair MM Richardson, Keith A Crandall, Christopher M Austin
Journal article | 2009 | Molecular Phylogenetics and Evolution
Sea-level changes and palaeo-ranges: reconstruction of ancient shorelines and river drainages and the phylogeography of the Australian land crayfish Engaeus sericatus Clark (Decapoda: Parastacidae)
Mark B Schultz, Daniel A Ierodiaconou, Sarah A Smith, Pierre Horwitz, Alastair MM Richardson, Keith A Crandall, Christopher M Austin
Journal article | 2008 | Molecular Ecology
Cryptic diversity in Engaeus Erichson, Geocharax Clark and Gramastacus Riek (Decapoda : parastacidae) revealed by mitochondrial 16S rDNA sequences
Mark B Schultz, Sarah A Smith, Alastair MM Richardson, Pierre Horwitz, Keith A Crandall, Christopher M Austin
Journal article | 2007 | Invertebrate Systematics
Validation of a single-step, single-tube reverse transcription-loop-mediated isothermal amplification assay for rapid detection of SARS-CoV-2 RNA
Jean YH Lee, Nickala Best, Julie McAuley, Jessica L Porter, Torsten Seemann, Mark B Schultz, Michelle Sait, Nicole Orlando, Karolina Mercoulia, Susan A Ballard, Julian Druce, Thomas Tran, Mike G Catton, Melinda J Pryor, Huanhuan L Cui, Angela Luttick, Sean McDonald, Arran Greenhalgh, Jason C Kwong, Norelle L Sherry, et al.
2.AbstractIntroductionThe SARS-CoV-2 pandemic of 2020 has resulted in unparalleled requirements for RNA extraction kits and enzyme..
Honours, Awards and Fellowships
Trends in Parasitology prize for Best Collaborative Work at the 2011 Malaria in Melbourne conference, Royal Melbourne Hospital
Microbiology And Immunology
American Society for Microbiology
International Society for Computational Biology
British Society for Antimicrobial Chemotherapy (BSAC)
International Society of Chemotherapy (ISC)
Victorian Infection and Immunity Network (VIIN)
Australian Society of Antimicrobials (ASA)
Doherty Institute'S Eqis Committee
Equity in Science (EQiS) Committee, Doherty Institute
Australasian Society for Infectious Diseases (ASID)
Australasian Genomics Technologies Association (AGTA)
Australian Bioinformatics and Computational Biology Society (ABACBS)
Doctor of Philosophy
Charles Darwin University
Bachelor of Science (Honours)
Bachelor of Science (Aquatic Science)