Lianyi Zhang

Porphyromonas gingivalis Gingipains Display Transpeptidation Activity

Lianyi Zhang, Paul D Veith, N Laila Huq, Yu-Yen Chen, Christine A Seers, Keith J Cross, Dhana G Gorasia, Eric C Reynolds

Journal article  |  2018  |  JOURNAL OF PROTEOME RESEARCH

Porphyromonas gingivalis is a keystone periodontal pathogen that has been associated with autoimmune disorders. The cell surface p..

PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System

Jacqueline E Heath, Christine A Seers, Paul D Veith, Catherine A Butler, Nor A Nor Muhammad, Yu-Yen Chen, Nada Slakeski, Benjamin Peng, Lianyi Zhang, Stuart G Dashper, Keith J Cross, Steven M Cleal, Caroline Moore, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

Porphyromonas gingivalis utilises the Bacteroidetes-specific type IX secretion system (T9SS) to export proteins across the outer m..

Characterisation of the Porphyromonas gingivalis Manganese Transport Regulator Orthologue

Lianyi Zhang, Catherine A Butler, Hasnah SG Khan, Stuart G Dashper, Christine A Seers, Paul D Veith, Jian-Guo Zhang, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

PgMntR is a predicted member of the DtxR family of transcriptional repressors responsive to manganese in the anaerobic periodontal..

The interplay between iron, haem and manganese in Porphyromonas gingivalis

CA Butler, SG Dashper, HSG Khan, L Zhang, EC Reynolds

Journal article  |  2015  |  Journal of Oral Biosciences

Background Transition metals including iron and manganese are necessary for life because of their ability to donate and accept ele..

The interplay between iron, haem and manganese in Porphyromonas gingivalis

Catherine A Butler, Stuart G Dashper, Hasnah SG Khan, Lianyi Zhang, Eric C Reynolds

Journal article  |  2015  |  JOURNAL OF ORAL BIOSCIENCES

Receptor-interacting Protein Kinase 4 and Interferon Regulatory Factor 6 Function as a Signaling Axis to Regulate Keratinocyte Differentiation

Mei Qi Kwa, Jennifer Huynh, Jiamin Aw, Lianyi Zhang, Nguyen Thao, Eric C Reynolds, Matthew J Sweet, John A Hamilton, Glen M Scholz

Journal article  |  2014  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Receptor-interacting protein kinase 4 (RIPK4) and interferon regulatory factor 6 (IRF6) are critical regulators of keratinocyte di..

The Porphyromonas gingivalis Ferric Uptake Regulator Orthologue Binds Hemin and Regulates Hemin-Responsive Biofilm Development

Catherine A Butler, Stuart G Dashper, Lianyi Zhang, Christine A Seers, Helen L Mitchell, Deanne V Catmull, Michelle D Glew, Jacqueline E Heath, Yan Tan, Hasnah SG Khan, Eric C Reynolds

Journal article  |  2014  |  PLOS ONE

Porphyromonas gingivalis is a Gram-negative pathogen associated with the biofilm-mediated disease chronic periodontitis. P. gingiv..

Propeptide-Mediated Inhibition of Cognate Gingipain Proteinases

N Laila Huq, Christine A Seers, Elena CY Toh, Stuart G Dashper, Nada Slakeski, Lianyi Zhang, Brent R Ward, Vincent Meuric, Dina Chen, Keith J Cross, Eric C Reynolds

Journal article  |  2013  |  PLOS ONE

Porphyromonas gingivalis is a major pathogen associated with chronic periodontitis. The organism's cell-surface cysteine proteinas..

Reversible redox regulation of specificityof Arg-gingipain B in Porphyromonas gingivalis

Yu-Yen Chen, Christine A Seers, Nada Slakeski, Caroline Moore, Lianyi Zhang, Eric C Reynolds

Journal article  |  2013  |  FEBS LETTERS

Arg-gingipain B (RgpB), a major virulence factor secreted by the periodontal pathogen Porphyromonas gingivalis is an Arg-specific ..

Electron paramagnetic resonance characterization of the copper-resistance protein PcoC from Escherichia coli

Simon C Drew, Karrera Y Djoko, Lianyi Zhang, Melissa Koay, John F Boas, John R Pilbrow, Zhiguang Xiao, Kevin J Barnham, Anthony G Wedd

Journal article  |  2008  |  JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Continuous-wave and pulsed electron paramagnetic resonance have been applied to the study of the Cu(II) site of the copper-resista..