Katrina Walsh

Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis

Georgina E Riddiough, Theodora Fifis, Katrina A Walsh, Vijayaragavan Muralidharan, Christopher Christophi, Bang M Tran, Elizabeth Vincan, Marcos V Perini

Journal article  |  2021  |  CANCERS

(1) Background: Recent clinical and experimental data suggests that the liver's regenerative response following partial hepatectom..

A review of T helper 17 cell-related cytokines in serum and saliva in periodontitis

Nidhi Medara, Jason C Lenzo, Katrina A Walsh, Eric C Reynolds, Ivan B Darby, Neil M O'Brien-Simpson

Journal article  |  2021  |  CYTOKINE

Periodontitis is a chronic inflammatory disease with a complex underlying immunopathology. Cytokines, as molecular mediators of in..

Peripheral memory T-cell profile is modified in patients undergoing periodontal management

Nidhi Medara, Jason C Lenzo, Katrina A Walsh, James A Holden, Eric C Reynolds, Ivan B Darby, Neil M O'Brien-Simpson

Journal article  |  2020  |  JOURNAL OF CLINICAL PERIODONTOLOGY

AIMS: T-cells are known to have a role in periodontitis, however, the effect of periodontal therapy on peripheral memory T-cells i..

Peripheral T helper cell profiles during management of periodontitis

Nidhi Medara, Jason C Lenzo, Katrina A Walsh, Neil M O'Brien-Simpson, Eric C Reynolds, Ivan B Darby

Journal article  |  2020  |  JOURNAL OF CLINICAL PERIODONTOLOGY

AIM: Periodontitis has been associated with other systemic diseases with underlying inflammation responsible for the shared link. ..

Acute phase protein and cytokine levels in serum and saliva: A comparison of detectable levels and correlations in a depressed and healthy adolescent sample (vol 34, pg 164, 2013)

Michelle L Byrne, Neil M O'Brien-Simpson, Eric C Reynolds, Katrina A Walsh, Katrina Laughton, Joanna M Waloszek, Michael J Woods, John Trinder, Nicholas B Allen

Journal article  |  2020  |  BRAIN BEHAVIOR AND IMMUNITY

The authors regret that upon further inspection of the data from this study, although the four acute phase proteins reported in th..

T helper 17 cell-related cytokines in serum and saliva during management of periodontitis

Nidhi Medara, Jason C Lenzo, Katrina A Walsh, Ivan B Darby, Neil M O'Brien-Simpson, Eric C Reynolds

Journal article  |  2020  |  CYTOKINE

AIM: T helper (Th)17 cells are implicated in the pathogenesis of periodontitis. This study investigated the effect of periodontal ..

Peripheral neutrophil phenotypes during management of periodontitis

Nidhi Medara, Jason C Lenzo, Katrina A Walsh, Eric C Reynolds, Neil M O'Brien-Simpson, Ivan B Darby

Journal article  |  2020  |  JOURNAL OF PERIODONTAL RESEARCH

BACKGROUND AND OBJECTIVES: Neutrophils are emerging as a key player in periodontal pathogenesis. The surface expression of cellula..

Immunomodulatory effects of renin-angiotensin system inhibitors on T lymphocytes in mice with colorectal liver metastases

Dora Lucia Vallejo Ardila, Katrina A Walsh, Theodora Fifis, Rita Paolini, Georgios Kastrappis, Christopher Christophi, Marcos Vinicius Perini

Journal article  |  2020  |  JOURNAL FOR IMMUNOTHERAPY OF CANCER

BACKGROUND: It is now recognized that many anticancer treatments positively modulate the antitumor immune response. Clinical and e..

Inhibition of PAK1 suppresses pancreatic cancer by stimulation of anti-tumour immunity through down-regulation of PD-L1

Kai Wang, Yifan Zhan, Huynh Nhi, Chelsea Dumesny, Xiao Wang, Khashayer Asadi, David Herrmann, Paul Timpson, Yang Yang, Katrina Walsh, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2020  |  CANCER LETTERS

Immunotherapies have not yielded significant clinical benefits for pancreatic ductal adenocarcinoma (PDA) because of the existence..

Renin-angiotensin inhibitors reprogram tumor immune microenvironment: A comprehensive view of the influences on anti-tumor immunity.

Dora L Vallejo-Ardila, Theodora Fifis, Louise M Burrell, Katrina Walsh, Christopher Christophi

Journal article  |  2018  |  Oncotarget

Renin-angiotensin system inhibitors (RASi) have shown potential anti-tumor effects that may have a significant impact in cancer th..